Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein

CHARMM-GUIMembrane Buildertoward realistic biological membrane simulations

(2014) Emilia L. Wu et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

(2014) Smriti Mishra et al.   eLife

On the Origin of Large Flexibility of P-glycoprotein in the Inward-facing State

(2013) Po-Chao Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Mechanistic picture for conformational transition of a membrane transporter at atomic resolution

(2013) M. Moradi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Refined structures of mouse P-glycoprotein

(2013) Jingzhi Li et al.   PROTEIN SCIENCE

DEER Distance Measurements on Proteins

(2012) Gunnar Jeschke   Annual Review of Physical Chemistry

Mechanism of the ABC transporter ATPase domains: catalytic models and the biochemical and biophysical record

(2012) Peter M. Jones et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans

(2012) Mi Sun Jin et al.   NATURE

P-glycoprotein Retains Drug-stimulated ATPase Activity upon Covalent Linkage of the Two Nucleotide Binding Domains at Their C-terminal Ends

(2011) Brandy Verhalen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toward the Fourth Dimension of Membrane Protein Structure: Insight into Dynamics from Spin-Labeling EPR Spectroscopy

(2011) Hassane S. Mchaourab et al.   STRUCTURE

Characterization of an Asymmetric Occluded State of P-glycoprotein with Two Bound Nucleotides

(2010) Alena Siarheyeva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rotamer libraries of spin labelled cysteines for protein studies

(2010) Yevhen Polyhach et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

CHARMM-GUI Membrane Builder for Mixed Bilayers and Its Application to Yeast Membranes

(2009) Sunhwan Jo et al.   BIOPHYSICAL JOURNAL

Mapping Daunorubicin-binding Sites in the ATP-binding Cassette Transporter MsbA Using Site-specific Quenching by Spin Labels

(2009) Smriti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Conformational Cycle of the ABC Transporter MsbA in Liposomes: Detailed Analysis Using Double Electron–Electron Resonance Spectroscopy

(2009) Ping Zou et al.   JOURNAL OF MOLECULAR BIOLOGY

ABC transporters: the power to change

(2009) Douglas C. Rees et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

PRALINETM: a strategy for improved multiple alignment of transmembrane proteins

(2008) W. Pirovano et al.   BIOINFORMATICS

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

ABC multidrug transporters: structure, function and role in chemoresistance

(2007) Frances J Sharom   PHARMACOGENOMICS