The Josephin domain (JD) containing proteins are predicted to bind to the same interactors: Implications for spinocerebellar ataxia type 3 (SCA3) studies using Drosophila melanogaster mutants
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Josephin domain (JD) containing proteins are predicted to bind to the same interactors: Implications for spinocerebellar ataxia type 3 (SCA3) studies using Drosophila melanogaster mutants
Authors
Keywords
-
Journal
Frontiers in Molecular Neuroscience
Volume 16, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2023-03-15
DOI
10.3389/fnmol.2023.1140719
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A perspective on Drosophila genetics and its insight into human neurodegenerative disease
- (2022) Nancy M. Bonini Frontiers in Molecular Biosciences
- Neurodegenerative phosphoprotein signaling landscape in models of SCA3
- (2021) Anna S. Sowa et al. Molecular Brain
- Highly accurate protein structure prediction with AlphaFold
- (2021) John Jumper et al. NATURE
- Highly accurate protein structure prediction for the human proteome
- (2021) Kathryn Tunyasuvunakool et al. NATURE
- Between Interactions and Aggregates: The PolyQ Balance
- (2021) Pablo Mier et al. Genome Biology and Evolution
- A Novel SCA3 Knock-in Mouse Model Mimics the Human SCA3 Disease Phenotype Including Neuropathological, Behavioral, and Transcriptional Abnormalities Especially in Oligodendrocytes
- (2021) Eva Haas et al. MOLECULAR NEUROBIOLOGY
- The Gene Ontology resource: enriching a GOld mine
- (2020) et al. NUCLEIC ACIDS RESEARCH
- EvoPPI 1.0: a Web Platform for Within- and Between-Species Multiple Interactome Comparisons and Application to Nine PolyQ Proteins Determining Neurodegenerative Diseases
- (2019) Noé Vázquez et al. Interdisciplinary Sciences-Computational Life Sciences
- Altered Levels of Proteins and Phosphoproteins, in the Absence of Early Causative Transcriptional Changes, Shape the Molecular Pathogenesis in the Brain of Young Presymptomatic Ki91 SCA3/MJD Mouse
- (2019) Kalina Wiatr et al. MOLECULAR NEUROBIOLOGY
- ATXN1 N-terminal region explains the binding differences of wild-type and expanded forms
- (2019) Sara Rocha et al. BMC Medical Genomics
- Ensembl 2020
- (2019) Andrew D Yates et al. NUCLEIC ACIDS RESEARCH
- Pathogenesis of SCA3 and implications for other polyglutamine diseases
- (2019) Hayley S. McLoughlin et al. NEUROBIOLOGY OF DISEASE
- Machado-Joseph disease / Spinocerebellar ataxia type 3:lessons from disease pathogenesis and clues into therapy
- (2018) Carlos Matos et al. JOURNAL OF NEUROCHEMISTRY
- Polyglutamine expansion diseases: More than simple repeats
- (2018) Alexandra Silva et al. JOURNAL OF STRUCTURAL BIOLOGY
- Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model
- (2018) Lodewijk J. A. Toonen et al. Molecular Neurodegeneration
- Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function
- (2018) Line V. Kristensen et al. NEUROCHEMISTRY INTERNATIONAL
- Cysteine Metabolism in Neuronal Redox Homeostasis
- (2018) Bindu D. Paul et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Large Scale Analyses and Visualization of Adaptive Amino Acid Changes Projects
- (2018) Noé Vázquez et al. Interdisciplinary Sciences-Computational Life Sciences
- Physiological and pathophysiological characteristics of ataxin-3 isoforms
- (2018) Daniel Weishäupl et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools
- (2018) Huaiyu Mi et al. NUCLEIC ACIDS RESEARCH
- Bioinformatics Protocols for Quickly Obtaining Large-Scale Data Sets for Phylogenetic Inferences
- (2018) Hugo López-Fernández et al. Interdisciplinary Sciences-Computational Life Sciences
- The Evolution and Functional Diversification of the Deubiquitinating Enzyme Superfamily
- (2017) Caitlyn Vlasschaert et al. Genome Biology and Evolution
- FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
- (2017) David P Leader et al. NUCLEIC ACIDS RESEARCH
- Ataxin-3 promotes genome integrity by stabilizing Chk1
- (2017) Yingfeng Tu et al. NUCLEIC ACIDS RESEARCH
- The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes
- (2016) G.C.P. van Zundert et al. JOURNAL OF MOLECULAR BIOLOGY
- Neurodegenerative diseases
- (2016) Marie-Thérèse Heemels NATURE
- Genome evolution in the allotetraploid frog Xenopus laevis
- (2016) Adam M. Session et al. NATURE
- Mitochondrial dynamics and quality control in Huntington's disease
- (2016) Pedro Guedes-Dias et al. NEUROBIOLOGY OF DISEASE
- Promoter Variation and Expression Levels of Inflammatory Genes IL1A, IL1B, IL6 and TNF in Blood of Spinocerebellar Ataxia Type 3 (SCA3) Patients
- (2016) Mafalda Raposo et al. NEUROMOLECULAR MEDICINE
- Studying polyglutamine diseases in Drosophila
- (2015) Zhen Xu et al. EXPERIMENTAL NEUROLOGY
- The I-TASSER Suite: protein structure and function prediction
- (2015) Jianyi Yang et al. NATURE METHODS
- I-TASSER server: new development for protein structure and function predictions
- (2015) Jianyi Yang et al. NUCLEIC ACIDS RESEARCH
- UBA1: At the Crossroads of Ubiquitin Homeostasis and Neurodegeneration
- (2015) Ewout J.N. Groen et al. TRENDS IN MOLECULAR MEDICINE
- Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins
- (2015) Fabian Hosp et al. Cell Reports
- Inactivation of PNKP by Mutant ATXN3 Triggers Apoptosis by Activating the DNA Damage-Response Pathway in SCA3
- (2015) Rui Gao et al. PLoS Genetics
- The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis
- (2015) Arpita Chatterjee et al. PLoS Genetics
- Interactions of ataxin-3 with its molecular partners in the protein machinery that sorts protein aggregates to the aggresome
- (2014) Marcella Bonanomi et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Whole-genome duplication in teleost fishes and its evolutionary consequences
- (2014) Stella M. K. Glasauer et al. MOLECULAR GENETICS AND GENOMICS
- Investigation of the Josephin Domain Protein-Protein Interaction by Molecular Dynamics
- (2014) Marco A. Deriu et al. PLoS One
- Ubiquitin ligase ITCH recruitment suppresses the aggregation and cellular toxicity of cytoplasmic misfolded proteins
- (2014) Deepak Chhangani et al. Scientific Reports
- Aggregation of polyglutamine-expanded ataxin-3 sequesters its specific interacting partners into inclusions: Implication in a loss-of-function pathology
- (2014) Hui Yang et al. Scientific Reports
- Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners
- (2013) Spyros Petrakis et al. BIOESSAYS
- JosD1, a Membrane-targeted Deubiquitinating Enzyme, Is Activated by Ubiquitination and Regulates Membrane Dynamics, Cell Motility, and Endocytosis
- (2013) Takahiro Seki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SUMO-1 Modification on K166 of PolyQ-Expanded aTaxin-3 Strengthens Its Stability and Increases Its Cytotoxicity
- (2013) Ya-Fang Zhou et al. PLoS One
- Impact of whole-genome duplication on vertebrate development and evolution
- (2013) Masanori Kasahara SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases
- (2013) Kyota Fujita et al. Nature Communications
- Brain pathology of spinocerebellar ataxias
- (2012) Kay Seidel et al. ACTA NEUROPATHOLOGICA
- An anatomically comprehensive atlas of the adult human brain transcriptome
- (2012) Michael J. Hawrylycz et al. NATURE
- Development and application of a DNA microarray-based yeast two-hybrid system
- (2012) Bernhard Suter et al. NUCLEIC ACIDS RESEARCH
- Evolution and function of CAG/polyglutamine repeats in protein–protein interaction networks
- (2012) Martin H. Schaefer et al. NUCLEIC ACIDS RESEARCH
- Large-Scale Screen for Modifiers of Ataxin-3-Derived Polyglutamine-Induced Toxicity in Drosophila
- (2012) Hannes Voßfeldt et al. PLoS One
- Compromised mitochondrial complex II in models of Machado–Joseph disease
- (2011) Mário N. Laço et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- An integrative approach to ortholog prediction for disease-focused and other functional studies
- (2011) Yanhui Hu et al. BMC BIOINFORMATICS
- FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3
- (2011) Julieta Araujo et al. HUMAN MOLECULAR GENETICS
- Ataxin-3 Deubiquitination Is Coupled to Parkin Ubiquitination via E2 Ubiquitin-conjugating Enzyme
- (2011) Thomas M. Durcan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
- (2011) F. Sievers et al. Molecular Systems Biology
- CPORT: A Consensus Interface Predictor and Its Performance in Prediction-Driven Docking with HADDOCK
- (2011) Sjoerd J. de Vries et al. PLoS One
- Co-Chaperone HSJ1a Dually Regulates the Proteasomal Degradation of Ataxin-3
- (2011) Xue-Chao Gao et al. PLoS One
- Episodic radiations in the fly tree of life
- (2011) B. M. Wiegmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toward understanding Machado–Joseph disease
- (2011) Maria do Carmo Costa et al. PROGRESS IN NEUROBIOLOGY
- A Genomewide RNA Interference Screen for Modifiers of Aggregates Formation by Mutant Huntingtin in Drosophila
- (2010) S. Zhang et al. GENETICS
- Silencing ataxin-3 mitigates degeneration in a rat model of Machado–Joseph disease: no role for wild-type ataxin-3?
- (2010) Sandro Alves et al. HUMAN MOLECULAR GENETICS
- The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability
- (2010) Thomas M. Durcan et al. HUMAN MOLECULAR GENETICS
- Crystal Structure of a Josephin-Ubiquitin Complex
- (2010) Stephen D. Weeks et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A mitochondrial ubiquitin ligase MITOL controls cell toxicity of polyglutamine-expanded protein
- (2010) Ayumu Sugiura et al. MITOCHONDRION
- I-TASSER: a unified platform for automated protein structure and function prediction
- (2010) Ambrish Roy et al. Nature Protocols
- TranslatorX: multiple alignment of nucleotide sequences guided by amino acid translations
- (2010) Federico Abascal et al. NUCLEIC ACIDS RESEARCH
- FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments
- (2010) Morgan N. Price et al. PLoS One
- Defining the Human Deubiquitinating Enzyme Interaction Landscape
- (2009) Mathew E. Sowa et al. CELL
- The (CAG)n tract of Machado–Joseph Disease gene (ATXN3): a comparison between DNA and mRNA in patients and controls
- (2009) Conceição Bettencourt et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation
- (2009) Zheng Ying et al. HUMAN MOLECULAR GENETICS
- CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3
- (2009) Thorsten Mueller et al. HUMAN MOLECULAR GENETICS
- Proteomic and biochemical analyses unveil tight interaction of ataxin-3 with tubulin
- (2009) Serena Mazzucchelli et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- FastTree: Computing Large Minimum Evolution Trees with Profiles instead of a Distance Matrix
- (2009) M. N. Price et al. MOLECULAR BIOLOGY AND EVOLUTION
- The evolutionary significance of ancient genome duplications
- (2009) Yves Van de Peer et al. NATURE REVIEWS GENETICS
- Increased transcript diversity: novel splicing variants of Machado–Joseph Disease gene (ATXN3)
- (2009) Conceição Bettencourt et al. NEUROGENETICS
- The Deubiquitinating Enzyme Ataxin-3, a Polyglutamine Disease Protein, Edits Lys63Linkages in Mixed Linkage Ubiquitin Chains
- (2008) Brett J. Winborn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Polyglutamine-expanded ataxin-3 causes cerebellar dysfunction of SCA3 transgenic mice by inducing transcriptional dysregulation
- (2008) An-Hsun Chou et al. NEUROBIOLOGY OF DISEASE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started