- Home
- Publications
- Publication Search
- Publication Details
Title
Ataxin-3 promotes genome integrity by stabilizing Chk1
Authors
Keywords
-
Journal
NUCLEIC ACIDS RESEARCH
Volume 45, Issue 8, Pages 4532-4549
Publisher
Oxford University Press (OUP)
Online
2017-02-09
DOI
10.1093/nar/gkx095
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress
- (2015) Yeran Yang et al. NUCLEIC ACIDS RESEARCH
- Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage
- (2015) Caroline Park et al. Nature Communications
- Inactivation of PNKP by Mutant ATXN3 Triggers Apoptosis by Activating the DNA Damage-Response Pathway in SCA3
- (2015) Rui Gao et al. PLoS Genetics
- The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis
- (2015) Arpita Chatterjee et al. PLoS Genetics
- USP7 controls Chk1 protein stability by direct deubiquitination
- (2014) Ignacio Alonso-de Vega et al. CELL CYCLE
- ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1
- (2014) Peijing Zhang et al. NATURE CELL BIOLOGY
- Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity
- (2014) Ryotaro Nishi et al. NATURE CELL BIOLOGY
- HERC2-USP20 axis regulates DNA damage checkpoint through Claspin
- (2014) Jian Yuan et al. NUCLEIC ACIDS RESEARCH
- HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability
- (2014) Min Zhu et al. NUCLEIC ACIDS RESEARCH
- Roles of Chk1 in cell biology and cancer therapy
- (2013) Youwei Zhang et al. INTERNATIONAL JOURNAL OF CANCER
- Candidate tumor suppressor BTG3 maintains genomic stability by promoting Lys63-linked ubiquitination and activation of the checkpoint kinase CHK1
- (2013) Y.-C. Cheng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma
- (2012) Jian Hong et al. JOURNAL OF CLINICAL INVESTIGATION
- Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancer
- (2012) J Xu et al. ONCOGENE
- USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation
- (2011) Jean-Hugues Guervilly et al. HUMAN MOLECULAR GENETICS
- The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis
- (2011) Kirsten Kuhlbrodt et al. NATURE CELL BIOLOGY
- Polyglutamine diseases: The special case of ataxin-3 and Machado–Joseph disease
- (2011) Carlos A. Matos et al. PROGRESS IN NEUROBIOLOGY
- Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity
- (2010) Jian-Ming Feng et al. CANCER BIOLOGY & THERAPY
- USP10 Regulates p53 Localization and Stability by Deubiquitinating p53
- (2010) Jian Yuan et al. CELL
- Chk1 Haploinsufficiency Results in Anemia and Defective Erythropoiesis
- (2010) Nathan C. Boles et al. PLoS One
- Understanding the Role of the Josephin Domain in the PolyUb Binding and Cleavage Properties of Ataxin-3
- (2010) Giuseppe Nicastro et al. PLoS One
- Chk1 suppressed cell death
- (2010) Mark Meuth Cell Division
- DDB1 Targets Chk1 to the Cul4 E3 Ligase Complex in Normal Cycling Cells and in Cells Experiencing Replication Stress
- (2009) V. Leung-Pineda et al. CANCER RESEARCH
- Proteomic and biochemical analyses unveil tight interaction of ataxin-3 with tubulin
- (2009) Serena Mazzucchelli et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Novel Positive Feedback Loop between Cdk1 and Chk1 in the Nucleus during G2/M Transition
- (2009) Masato Enomoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The F Box Protein Fbx6 Regulates Chk1 Stability and Cellular Sensitivity to Replication Stress
- (2009) You-Wei Zhang et al. MOLECULAR CELL
- Breaking the chains: structure and function of the deubiquitinases
- (2009) David Komander et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Chk1 deficiency in the mouse small intestine results in p53-independent crypt death and subsequent intestinal compensation
- (2009) K R Greenow et al. ONCOGENE
- Chk1 Is a Histone H3 Threonine 11 Kinase that Regulates DNA Damage-Induced Transcriptional Repression
- (2008) Midori Shimada et al. CELL
- SCA3: Neurological features, pathogenesis and animal models
- (2008) Olaf Riess et al. CEREBELLUM
- Chk1 and Claspin potentiate PCNA ubiquitination
- (2008) X. H. Yang et al. GENES & DEVELOPMENT
- The Deubiquitinating Enzyme Ataxin-3, a Polyglutamine Disease Protein, Edits Lys63Linkages in Mixed Linkage Ubiquitin Chains
- (2008) Brett J. Winborn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deranged Calcium Signaling and Neurodegeneration in Spinocerebellar Ataxia Type 3
- (2008) X. Chen et al. JOURNAL OF NEUROSCIENCE
- Study of subcellular localization and proteolysis of ataxin-3
- (2008) Chiara Pozzi et al. NEUROBIOLOGY OF DISEASE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started