Large-Scale Screen for Modifiers of Ataxin-3-Derived Polyglutamine-Induced Toxicity in Drosophila

The Mitochondrial Chaperone Protein TRAP1 Mitigates α-Synuclein Toxicity

(2012) Erin K. Butler et al.   PLoS Genetics

Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation

(2011) Surendra S. Ambegaokar et al.   HUMAN MOLECULAR GENETICS

Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1

(2011) Wing Man Chan et al.   HUMAN MOLECULAR GENETICS

A Genetic Screening Strategy Identifies Novel Regulators of the Proteostasis Network

(2011) M. Catarina Silva et al.   PLoS Genetics

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

A Genomewide RNA Interference Screen for Modifiers of Aggregates Formation by Mutant Huntingtin in Drosophila

(2010) S. Zhang et al.   GENETICS

Improved Activities of CREB Binding Protein, Heterogeneous Nuclear Ribonucleoproteins and Proteasome Following Downregulation of Noncoding hsr  Transcripts Help Suppress Poly(Q) Pathogenesis in Fly Models

(2010) M. Mallik et al.   GENETICS

Nuclear Aggregation of Polyglutamine-expanded Ataxin-3

(2010) Peter Breuer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute Polyglutamine Expression in Inducible Mouse Model Unravels Ubiquitin/Proteasome System Impairment and Permanent Recovery Attributable to Aggregate Formation

(2010) Z. Ortega et al.   JOURNAL OF NEUROSCIENCE

Autosomal dominant cerebellar ataxias: polyglutamine expansions and beyond

(2010) Alexandra Durr   LANCET NEUROLOGY

A DNAJB Chaperone Subfamily with HDAC-Dependent Activities Suppresses Toxic Protein Aggregation

(2010) Jurre Hageman et al.   MOLECULAR CELL

Repeat expansion disease: progress and puzzles in disease pathogenesis

(2010) Albert R. La Spada et al.   NATURE REVIEWS GENETICS

Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function

(2009) James C Costello et al.   GENOME BIOLOGY

Ontologizer 2.0--a multifunctional tool for GO term enrichment analysis and data exploration

(2008) S. Bauer et al.   BIOINFORMATICS

Reprogramming mRNA translation during stress

(2008) Satoshi Yamasaki et al.   CURRENT OPINION IN CELL BIOLOGY

Sodium dodecyl sulfate-insoluble oligomers are involved in polyglutamine degeneration

(2008) S. L. Alan Wong et al.   FASEB JOURNAL

RNA toxicity is a component of ataxin-3 degeneration in Drosophila

(2008) Ling-Bo Li et al.   NATURE

Polyglutamine Genes Interact to Modulate the Severity and Progression of Neurodegeneration in Drosophila

(2008) Derek Lessing et al.   PLOS BIOLOGY