Highly accurate protein structure prediction for the human proteome

Crystallographic molecular replacement using an in silico‐generated search model of SARS‐CoV ‐2 ORF8

(2021) Thomas G. Flower et al.   PROTEIN SCIENCE

Critical assessment of protein intrinsic disorder prediction

(2021) Marco Necci et al.   NATURE METHODS

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

High‐accuracy protein structure prediction in CASP14

(2021) Joana Pereira et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structure-based protein function prediction using graph convolutional networks

(2021) Vladimir Gligorijević et al.   Nature Communications

Improved protein structure prediction using potentials from deep learning

(2020) Andrew W. Senior et al.   NATURE

Improved protein structure prediction using predicted interresidue orientations

(2020) Jianyi Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Innovation in the Evolution of the Calcium-Dependent System of the Eukaryotic Endoplasmic Reticulum

(2020) Daniel E. Schäffer et al.   Frontiers in Genetics

Structure and mechanism of human diacylglycerol O-acyltransferase 1

(2020) Lie Wang et al.   NATURE

MobiDB-lite 3.0: fast consensus annotation of intrinsic disorder flavors in proteins

(2020) Marco Necci et al.   BIOINFORMATICS

The Gene Ontology resource: enriching a GOld mine

(2020) et al.   NUCLEIC ACIDS RESEARCH

UniProt: the universal protein knowledgebase in 2021

(2020) et al.   NUCLEIC ACIDS RESEARCH

Protein-level assembly increases protein sequence recovery from metagenomic samples manyfold

(2019) Martin Steinegger et al.   NATURE METHODS

Why do eukaryotic proteins contain more intrinsically disordered regions?

(2019) Walter Basile et al.   PLoS Computational Biology

Advances in protein structure prediction and design

(2019) Brian Kuhlman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Introducing “best single template” models as Reference Baseline for the Continuous Automated Model EvaluatiOn (CAMEO)

(2019) Juergen Haas et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Genome3D: integrating a collaborative data pipeline to expand the depth and breadth of consensus protein structure annotation

(2019) Ian Sillitoe et al.   NUCLEIC ACIDS RESEARCH

The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures

(2019) Antonina Andreeva et al.   NUCLEIC ACIDS RESEARCH

Critical assessment of methods of protein structure prediction (CASP)—Round XIII

(2019) Andriy Kryshtafovych et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Deep learning extends de novo protein modelling coverage of genomes using iteratively predicted structural constraints

(2019) Joe G. Greener et al.   Nature Communications

Protease-associated import systems are widespread in Gram-negative bacteria

(2019) Rhys Grinter et al.   PLoS Genetics

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

P2Rank: machine learning based tool for rapid and accurate prediction of ligand binding sites from protein structure

(2018) Radoslav Krivák et al.   Journal of Cheminformatics

Protein Data Bank: the single global archive for 3D macromolecular structure data

(2018) et al.   NUCLEIC ACIDS RESEARCH

CATH: expanding the horizons of structure-based functional annotations for genome sequences

(2018) Ian Sillitoe et al.   NUCLEIC ACIDS RESEARCH

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

Continuous Automated Model EvaluatiOn (CAMEO) complementing the critical assessment of structure prediction in CASP12

(2017) Jürgen Haas et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Wolfram Syndrome: Diagnosis, Management, and Treatment

(2016) Fumihiko Urano   Current Diabetes Reports

Finding Our Way in the Dark Proteome

(2016) Asmit Bhowmick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The coming of age of de novo protein design

(2016) Po-Ssu Huang et al.   NATURE

Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)

(2015) Kentaro Futatsugi et al.   JOURNAL OF MEDICINAL CHEMISTRY

GPCR-I-TASSER: A Hybrid Approach to G Protein-Coupled Receptor Structure Modeling and the Application to the Human Genome

(2015) Jian Zhang et al.   STRUCTURE

Large-scale determination of previously unsolved protein structures using evolutionary information

(2015) Sergey Ovchinnikov et al.   eLife

lDDT: a local superposition-free score for comparing protein structures and models using distance difference tests

(2013) Valerio Mariani et al.   BIOINFORMATICS

ModBase, a database of annotated comparative protein structure models and associated resources

(2013) Ursula Pieper et al.   NUCLEIC ACIDS RESEARCH

D2P2: database of disordered protein predictions

(2012) Matt E. Oates et al.   NUCLEIC ACIDS RESEARCH

The Proteome Folding Project: Proteome-scale prediction of structure and function

(2011) K. Drew et al.   GENOME RESEARCH

Roles of intrinsic disorder in protein–nucleic acid interactions

(2011) H. Jane Dyson   Molecular BioSystems

Wolfram syndrome and WFS1 gene

(2010) L Rigoli et al.   CLINICAL GENETICS

The structure of KPN03535 (gi|152972051), a novel putative lipoprotein fromKlebsiella pneumoniae, reveals an OB-fold

(2009) Debanu Das et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Protein structure prediction: when is it useful?

(2009) Yang Zhang   CURRENT OPINION IN STRUCTURAL BIOLOGY

Relative Stabilities of Conserved and Non-Conserved Structures in the OB-Fold Superfamily

(2009) Kaitlyn Guardino et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Discovery of a Potent, Selective, and Orally Efficacious Pyrimidinooxazinyl Bicyclooctaneacetic Acid Diacylglycerol Acyltransferase-1 Inhibitor

(2009) Alan M. Birch et al.   JOURNAL OF MEDICINAL CHEMISTRY