Pathogenicity and virulence of Aspergillus fumigatus

COVID-19-Associated Pulmonary Aspergillosis in a Tertiary Hospital

(2022) García-Clemente Marta et al.   Journal of Fungi

Aspergillus fumigatus—Host Interactions Mediating Airway Wall Remodelling in Asthma

(2022) Sara Namvar et al.   Journal of Fungi

Superinfection is associated with short-term outcome and mortality in viral respiratory tract infections during the fall-winter seasons 2016-2018 in the Greater Paris area: the SUPERFLUOUS study

(2022) Benjamin Davido et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

An Alanine Aminotransferase Is Required for Biofilm-Specific Resistance of Aspergillus fumigatus to Echinocandin Treatment

(2022) Joshua D. Kerkaert et al.   mBio

Increased Deaths From Fungal Infections During the Coronavirus Disease 2019 Pandemic—National Vital Statistics System, United States, January 2020–December 2021

(2022) Jeremy A W Gold et al.   CLINICAL INFECTIOUS DISEASES

Fungal-mediated lung allergic airway disease: The critical role of macrophages and dendritic cells

(2022) Julio Furlong-Silva et al.   PLoS Pathogens

COVID-19 patients share common, corticosteroid-independent features of impaired host immunity to pathogenic molds

(2022) Beeke Tappe et al.   Frontiers in Immunology

COVID-19-associated fungal infections

(2022) Martin Hoenigl et al.   Nature Microbiology

Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational study

(2022) Simon Feys et al.   Lancet Respiratory Medicine

The Clinical Characteristics of Patients With Nonneutropenic Invasive Pulmonary Aspergillosis

(2021) Lulu Liu et al.   Frontiers in Medicine

Mitochondrial Reactive Oxygen Species Regulate Immune Responses of Macrophages to Aspergillus fumigatus

(2021) Remi Hatinguais et al.   Frontiers in Immunology

Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis

(2021) Tonia Akoumianaki et al.   Cell Host & Microbe

Risk factors and outcome of pulmonary aspergillosis in critically ill coronavirus disease 2019 patients—a multinational observational study by the European Confederation of Medical Mycology

(2021) Juergen Prattes et al.   CLINICAL MICROBIOLOGY AND INFECTION

Aspergillus fumigatus In-Host HOG Pathway Mutation for Cystic Fibrosis Lung Microenvironment Persistence

(2021) Brandon S. Ross et al.   mBio

Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response

(2021) Monica Sueiro-Olivares et al.   PLOS BIOLOGY

The IL-1 Receptor Is Required to Maintain Neutrophil Viability and Function During Aspergillus fumigatus Airway Infection

(2021) Benjamin AWR Ralph et al.   Frontiers in Immunology

Transcription in fungal conidia before dormancy produces phenotypically variable conidia that maximize survival in different environments

(2021) Fang Wang et al.   Nature Microbiology

Nitrogen, Iron, and Zinc Acquisition: Key Nutrients to Aspergillus fumigatus Virulence

(2021) Uxue Perez-Cuesta et al.   Journal of Fungi

Characterisation of Aspergillus fumigatus Endocytic Trafficking within Airway Epithelial Cells Using High-Resolution Automated Quantitative Confocal Microscopy

(2021) Nagwa Ben-Ghazzi et al.   Journal of Fungi

Computed tomography features of pulmonary metastases from angiosarcoma: Lessons learned from one case study

(2021) Nina M. Adzic et al.   Radiology Case Reports

Host Lung Environment Limits Aspergillus fumigatus Germination through an SskA-Dependent Signaling Response

(2021) Marina E. Kirkland et al.   mSphere

Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation

(2020) Darin L. Wiesner et al.   Cell Host & Microbe

Influenza-Associated Pulmonary Aspergillosis: A Local or Global Lethal Combination?

(2020) Bart J A Rijnders et al.   CLINICAL INFECTIOUS DISEASES

Respiratory mycobiome and suggestion of inter-kingdom network during acute pulmonary exacerbation in cystic fibrosis

(2020) Perrine Soret et al.   Scientific Reports

Monocytes and the Host Response to Fungal Pathogens

(2020) Lena J. Heung   Frontiers in Cellular and Infection Microbiology

Murine Intraepithelial Dendritic Cells Interact With Phagocytic Cells During Aspergillus fumigatus-Induced Inflammation

(2020) Andrey O. Bogorodskiy et al.   Frontiers in Immunology

The Role of Pentraxin 3 in Aspergillosis: Reality and Prospects

(2020) Yuening Kang et al.   MYCOBIOLOGY

Environmental fungal sensitisation associates with poorer clinical outcomes in COPD

(2020) Pei Yee Tiew et al.   EUROPEAN RESPIRATORY JOURNAL

Exposure to mold proteases stimulates mucin production in airway epithelial cells through Ras/Raf1/ERK signal pathway

(2020) Xianxian Wu et al.   PLoS One

Mitochondrial reactive oxygen species as major effectors of antimicrobial immunity

(2020) Elena Shekhova   PLoS Pathogens

Prevalence of putative invasive pulmonary aspergillosis in critically ill patients with COVID-19

(2020) Alexandre Alanio et al.   Lancet Respiratory Medicine

Bronchial Epithelial Cells on the Front Line to Fight Lung Infection-Causing Aspergillus fumigatus

(2020) Jeanne Bigot et al.   Frontiers in Immunology

During Aspergillus Infection, Monocyte-Derived DCs, Neutrophils, and Plasmacytoid DCs Enhance Innate Immune Defense through CXCR3-Dependent Crosstalk

(2020) Yahui Guo et al.   Cell Host & Microbe

The fungal airway microbiome in cystic fibrosis and non-cystic fibrosis bronchiectasis

(2020) Leah Cuthbertson et al.   Journal of Cystic Fibrosis

Influenza Suppresses Neutrophil Recruitment to the Lung and Exacerbates Secondary Invasive Pulmonary Aspergillosis

(2020) Joshua M. Tobin et al.   JOURNAL OF IMMUNOLOGY

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence

(2020) Laure N. A. Ries et al.   PLoS Pathogens

Galectin-3 enhances neutrophil motility and extravasation into the airways during Aspergillus fumigatus infection

(2020) Brendan D. Snarr et al.   PLoS Pathogens

Secondary Bacterial Infections During Pulmonary Viral Disease: Phage Therapeutics as Alternatives to Antibiotics?

(2020) Prasanth Manohar et al.   Frontiers in Microbiology

Hyperglycemia suppresses the regulatory effect of hypoxia-inducible factor-1α in pulmonary Aspergillus fumigatus infection

(2020) Yao Ye et al.   Pathogens and Disease

Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2020) Joan B Soriano et al.   Lancet Respiratory Medicine

Thermotolerant and Thermophilic Mycobiota in Different Steps of Compost Maturation

(2020) Simone Di Piazza et al.   Microorganisms

Factoring in the Complexity of the Cystic Fibrosis Lung to Understand Aspergillus fumigatus and Pseudomonas aeruginosa Interactions

(2020) Emily Beswick et al.   Pathogens

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19

(2020) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

New Clinical Diagnostic Criteria for Allergic Bronchopulmonary Aspergillosis/Mycosis and its Validation

(2020) Koichiro Asano et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against Aspergillus fumigatus

(2020) Xi Wang et al.   JOURNAL OF IMMUNOLOGY

Fungal biofilm architecture produces hypoxic microenvironments that drive antifungal resistance

(2020) Caitlin H. Kowalski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The global impact of Aspergillus infection on COPD

(2020) Emily E. Hammond et al.   BMC Pulmonary Medicine

Phagolysosomal Survival Enables Non-lytic Hyphal Escape and Ramification Through Lung Epithelium During Aspergillus fumigatus Infection

(2020) Constanze Seidel et al.   Frontiers in Microbiology

A Human IRE1 Inhibitor Blocks the Unfolded Protein Response in the Pathogenic Fungus Aspergillus fumigatus and Suggests Noncanonical Functions within the Pathway

(2020) José P. Guirao-Abad et al.   mSphere

Transcriptional Profiling of Immune and Inflammatory Responses in the Context of SARS-CoV-2 Fungal Superinfection in a Human Airway Epithelial Model

(2020) Claire Nicolas de Lamballerie et al.   Microorganisms

Particulate β-glucan activates early and delayed phagosomal maturation and autophagy within macrophage in a NOX-2 dependent manner

(2020) Nida Fatima et al.   LIFE SCIENCES

Galactosaminogalactan (GAG) and its multiple roles in Aspergillus pathogenesis

(2019) Cornelia Speth et al.   Virulence

Endocytic Markers Associated with the Internalization and Processing of Aspergillus fumigatus Conidia by BEAS-2B Cells

(2019) Helen R. Clark et al.   mSphere

Pro-Inflammatory Responses in Human Bronchial Epithelial Cells Induced by Spores and Hyphal Fragments of Common Damp Indoor Molds

(2019) Elisabeth Øya et al.   International Journal of Environmental Research and Public Health

Invasive Aspergillosis in Solid Organ Transplant Recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

(2019) Shahid Husain et al.   CLINICAL TRANSPLANTATION

Cystic Fibrosis and Pseudomonas aeruginosa: the Host-Microbe Interface

(2019) Sankalp Malhotra et al.   CLINICAL MICROBIOLOGY REVIEWS

Airway inflammation in COPD- progress to precision medicine

(2019) Christopher Brightling et al.   EUROPEAN RESPIRATORY JOURNAL

“In sickness and in health” – how neutrophil extracellular trap (NET) works in infections, selected diseases and pregnancy

(2019) Paulina Niedźwiedzka-Rystwej et al.   Journal of Inflammation-London

Omalizumab for asthma and allergic bronchopulmonary aspergillosis in adults with cystic fibrosis

(2019) Angela Koutsokera et al.   Journal of Cystic Fibrosis

Human cystic fibrosis monocyte derived macrophages display no defect in acidification of phagolysosomes when measured by optical nanosensors

(2019) Sheonagh M. Law et al.   Journal of Cystic Fibrosis

Mac‐1 triggers neutrophil DNA extracellular trap formation to Aspergillus fumigatus independently of PAD4 histone citrullination

(2019) Juliana C. Silva et al.   JOURNAL OF LEUKOCYTE BIOLOGY

COPD overdiagnosis in primary care: a UK observational study of consistency of airflow obstruction

(2019) Lynn Josephs et al.   npj Primary Care Respiratory Medicine

Fungal biofilm morphology impacts hypoxia fitness and disease progression

(2019) Caitlin H. Kowalski et al.   Nature Microbiology

Aspergillus fumigatus and Aspergillosis in 2019

(2019) Jean-Paul Latgé et al.   CLINICAL MICROBIOLOGY REVIEWS

Aspergillus fumigatus cell wall promotes apical airway epithelial recruitment of human neutrophils

(2019) Michael B. Feldman et al.   INFECTION AND IMMUNITY

Cystic Fibrosis Lung Disease: An Overview

(2019) Nelson L Turcios   Respiratory Care

Global mortality associated with seasonal influenza epidemics: New burden estimates and predictors from the GLaMOR Project

(2019) John Paget et al.   Journal of Global Health

Molecular Mechanisms of Conidial Germination in Aspergillus spp.

(2019) Tim J. H. Baltussen et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

T Cell Antifungal Immunity and the Role of C-Type Lectin Receptors

(2019) Emily A. Speakman et al.   TRENDS IN IMMUNOLOGY

Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance

(2019) Patrícia Alves de Castro et al.   PLoS Genetics

Airway Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease: Role of Cigarette Smoke Exposure

(2018) Mahyar Aghapour et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

NETs in pneumonia: is just enough the right amount?

(2018) Robert D. Gray   EUROPEAN RESPIRATORY JOURNAL

Good cop, bad cop: anaerobes in cystic fibrosis airways

(2018) Lindsay J. Caverly et al.   EUROPEAN RESPIRATORY JOURNAL

Aspergillus fumigatus Detection and Risk Factors in Patients with COPD–Bronchiectasis Overlap

(2018) Stephanie Everaerts et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Twelve-month clinical outcomes of 206 patients with chronic pulmonary aspergillosis

(2018) Felix Bongomin et al.   PLoS One

Pattern recognition receptors in fungal immunity

(2018) Emmanuel C. Patin et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Airway epithelial phosphoinositide 3-kinase-δ contributes to the modulation of fungi-induced innate immune response

(2018) Jae Seok Jeong et al.   THORAX

Genetic deficiency of NOD2 confers resistance to invasive aspergillosis

(2018) Mark S. Gresnigt et al.   Nature Communications

Management of airway mucus hypersecretion in chronic airway inflammatory disease: Chinese expert consensus (English edition)

(2018) Yongchun Shen et al.   International Journal of Chronic Obstructive Pulmonary Disease

Collision of communicable and non-communicable disease epidemics—the case of HIV and COPD

(2018) Marie Stolbrink et al.   Lancet Global Health

Host-Derived Leukotriene B4 Is Critical for Resistance against Invasive Pulmonary Aspergillosis

(2018) Alayna K. Caffrey-Carr et al.   Frontiers in Immunology

Estimation of direct healthcare costs of fungal diseases in the United States

(2018) Kaitlin Benedict et al.   CLINICAL INFECTIOUS DISEASES

OUP accepted manuscript

(2018)   MEDICAL MYCOLOGY

OUP accepted manuscript

(2018)   MEDICAL MYCOLOGY

OUP accepted manuscript

(2018)   MEDICAL MYCOLOGY

Lung colonization by Aspergillus fumigatus is controlled by ZNF77

(2018) Sara Gago et al.   Nature Communications

Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing

(2018) Emily E. Rosowski et al.   PLoS Pathogens

FIBCD1 Binds Aspergillus fumigatus and Regulates Lung Epithelial Response to Cell Wall Components

(2018) Christine Schoeler Jepsen et al.   Frontiers in Immunology

Dropping acid: why is cystic fibrosis mucus abnormal?

(2018) Bruce K. Rubin et al.   EUROPEAN RESPIRATORY JOURNAL

Aspergillus fumigatus conidia stimulate lung epithelial cells (TC-1 JHU-1) to produce IL-12, IFNγ, IL-13 and IL-17 cytokines: Modulatory effect of propolis extract

(2018) A.R. Khosravi et al.   JOURNAL DE MYCOLOGIE MEDICALE

IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity

(2017) Cristina Cunha et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Corticosteroid treatment is associated with increased filamentous fungal burden in allergic fungal disease

(2017) Marcin G. Fraczek et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Impact of unresolved neutropenia in patients with neutropenia and invasive aspergillosis: a post hoc analysis of the SECURE trial

(2017) Dimitrios P Kontoyiannis et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Diagnostic Value of Galactomannan Antigen Test in Serum and Bronchoalveolar Lavage Fluid Samples from Patients with Nonneutropenic Invasive Pulmonary Aspergillosis

(2017) Wei Zhou et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Pulmonary immune responses against Aspergillus fumigatus are characterized by high frequencies of IL-17 producing T-cells

(2017) Hetty Jolink et al.   JOURNAL OF INFECTION

Estimating the burden of invasive and serious fungal disease in the United Kingdom

(2017) Matthew Pegorie et al.   JOURNAL OF INFECTION

Fungal Pathogens in CF Airways: Leave or Treat?

(2017) A. Singh et al.   MYCOPATHOLOGIA

Aspergillus Bronchitis in Patients with Cystic Fibrosis

(2017) Claudia Brandt et al.   MYCOPATHOLOGIA

Aspergillus fumigatus morphology and dynamic host interactions

(2017) Frank L. van de Veerdonk et al.   NATURE REVIEWS MICROBIOLOGY

Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death

(2017) Neta Shlezinger et al.   SCIENCE

Tuberculosis: Just the FAQs

(2017) Kristine M. Guinn et al.   mBio

Filamentous fungal carbon catabolite repression supports metabolic plasticity and stress responses essential for disease progression

(2017) Sarah R. Beattie et al.   PLoS Pathogens

The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression

(2017) Mark S. Gresnigt et al.   Frontiers in Immunology

Clinical outcome and prognostic factors associated with invasive pulmonary aspergillosis: An 11-year follow-up report from Taiwan

(2017) Kuo-Shao Sun et al.   PLoS One

Calcineurin Orchestrates Lateral Transfer of Aspergillus fumigatus during Macrophage Cell Death

(2016) Anand Shah et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Melanin targets LC3-associated phagocytosis (LAP): A novel pathogenetic mechanism in fungal disease

(2016) Georgios Chamilos et al.   Autophagy

Comparative transcriptome analysis revealing dormant conidia and germination associated genes in Aspergillus species: an essential role for AtfA in conidial dormancy

(2016) Daisuke Hagiwara et al.   BMC GENOMICS

Role of CFTR in epithelial physiology

(2016) Vinciane Saint-Criq et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America

(2016) Thomas F. Patterson et al.   CLINICAL INFECTIOUS DISEASES

Amino acid biosynthetic routes as drug targets for pulmonary fungal pathogens: what is known and why do we need to know more?

(2016) Jorge Amich et al.   CURRENT OPINION IN MICROBIOLOGY

Lung microbiome dynamics in COPD exacerbations

(2016) Zhang Wang et al.   EUROPEAN RESPIRATORY JOURNAL

Th17/Treg-related cytokine imbalance in sulfur mustard exposed and stable chronic obstructive pulmonary (COPD) patients: correlation with disease activity

(2016) Saber Imani et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Chitinase activation in patients with fungus-associated cystic fibrosis lung disease

(2016) Andreas Hector et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Calcineurin inhibitors impair neutrophil activity against Aspergillus fumigatus in allogeneic hematopoietic stem cell transplant recipients

(2016) Sébastien Imbert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inflammatory mechanisms in patients with chronic obstructive pulmonary disease

(2016) Peter J. Barnes   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The contribution of Aspergillus fumigatus stress responses to virulence and antifungal resistance

(2016) Neil A. Brown et al.   JOURNAL OF MICROBIOLOGY

From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

(2016) Gudio Veit et al.   MOLECULAR BIOLOGY OF THE CELL

TheAspergillus fumigatusSchASCH9kinase modulates SakAHOG1MAP kinase activity and it is essential for virulence

(2016) Patrícia Alves de Castro et al.   MOLECULAR MICROBIOLOGY

Aspergillosis and the role of mucins in cystic fibrosis

(2016) Abigail C. Cowley et al.   PEDIATRIC PULMONOLOGY

Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation

(2016) Mark J. Lee et al.   mBio

Heterogeneity among Isolates Reveals that Fitness in Low Oxygen Correlates with Aspergillus fumigatus Virulence

(2016) Caitlin H. Kowalski et al.   mBio

Allergic Bronchopulmonary Aspergillosis: A Perplexing Clinical Entity

(2016) Ashok Shah et al.   Allergy Asthma & Immunology Research

The role of Dectin-1/Raf-1 signal cascade in innate immune of human corneal epithelial cells against Aspergillus fumigatus infection

(2016)   International Journal of Ophthalmology

Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor

(2016) Mark S. Gresnigt et al.   Scientific Reports

A Sweet Response to a Sour Situation: The Role of Soluble Pattern Recognition Receptors in the Innate Immune Response to Invasive Aspergillus fumigatus Infections

(2016) Stefan Bidula et al.   PLoS Pathogens

Interactions of Aspergillus fumigatus Conidia with Airway Epithelial Cells: A Critical Review

(2016) Carys A. Croft et al.   Frontiers in Microbiology

Chronic pulmonary aspergillosis: help is on the way

(2016) The Lancet Respiratory Medicine   Lancet Respiratory Medicine

Developments in the diagnosis and treatment of allergic bronchopulmonary aspergillosis

(2016) Ritesh Agarwal et al.   Expert Review of Respiratory Medicine

Viral Evasion Strategies in Type I IFN Signaling – A Summary of Recent Developments

(2016) Katharina S. Schulz et al.   Frontiers in Immunology

Aspergillus fumigatus in the cystic fibrosis lung: pros and cons of azole therapy

(2016) Pierre Régis Burgel et al.   Infection and Drug Resistance

Pulmonary epithelial barrier function: some new players and mechanisms

(2015) Kieran Brune et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Omalizumab Treatment for Allergic Bronchopulmonary Aspergillosis in Cystic Fibrosis

(2015) Nagehan Emiralioglu et al.   ANNALS OF PHARMACOTHERAPY

Evidence for the involvement of cofilin in Aspergillus fumigatus internalization into type II alveolar epithelial cells

(2015) Zhiyao Bao et al.   BMC MICROBIOLOGY

Prevalence ofAspergillussensitization and allergic bronchopulmonary aspergillosis in cystic fibrosis: systematic review and meta-analysis

(2015) V. N. Maturu et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Components of the Calcium-Calcineurin Signaling Pathway in Fungal Cells and Their Potential as Antifungal Targets

(2015) Shuyuan Liu et al.   EUKARYOTIC CELL

Chronic pulmonary aspergillosis: rationale and clinical guidelines for diagnosis and management

(2015) David W. Denning et al.   EUROPEAN RESPIRATORY JOURNAL

Prevalence of meconium ileus marks the severity of mutations of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene

(2015) Annie Dupuis et al.   GENETICS IN MEDICINE

High osmolarity glycerol response PtcB phosphatase is important forAspergillus fumigatusvirulence

(2015) Lizziane K. Winkelströter et al.   MOLECULAR MICROBIOLOGY

Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets

(2015) Iram J Haq et al.   THORAX

Pulmonary macrophages: key players in the innate defence of the airways

(2015) Adam J Byrne et al.   THORAX

A fungal protease allergen provokes airway hyper-responsiveness in asthma

(2015) Nariman A. Balenga et al.   Nature Communications

CD103+ Dendritic Cells Control Th17 Cell Function in the Lung

(2015) Teresa Zelante et al.   Cell Reports

Recognition of Aspergillus fumigatus Hyphae by Human Plasmacytoid Dendritic Cells Is Mediated by Dectin-2 and Results in Formation of Extracellular Traps

(2015) Flávio V. Loures et al.   PLoS Pathogens

IL-1α Signaling Is Critical for Leukocyte Recruitment after Pulmonary Aspergillus fumigatus Challenge

(2015) Alayna K. Caffrey et al.   PLoS Pathogens

Compartment-Specific and Sequential Role of MyD88 and CARD9 in Chemokine Induction and Innate Defense during Respiratory Fungal Infection

(2015) Anupam Jhingran et al.   PLoS Pathogens

The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence

(2015) Vito Valiante et al.   Frontiers in Microbiology

Systemic cytokine signaling via IL-17 in smokers with obstructive pulmonary disease: a link to bacterial colonization?

(2015) Anders Lindén et al.   International Journal of Chronic Obstructive Pulmonary Disease

Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series

(2014) Corine E Delsing et al.   BMC INFECTIOUS DISEASES

CFTR: cystic fibrosis and beyond

(2014) M. A. Mall et al.   EUROPEAN RESPIRATORY JOURNAL

NADPH Oxidase Promotes Neutrophil Extracellular Trap Formation in Pulmonary Aspergillosis

(2014) Marc Röhm et al.   INFECTION AND IMMUNITY

Innate Immunity Induced by Fungal β-Glucans via Dectin-1 Signaling Pathway

(2014) Dong Hee Lee et al.   INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS

Reduced Nicotinamide Adenine Dinucleotide Phosphate Oxidase-Independent Resistance to Aspergillus fumigatus in Alveolar Macrophages

(2014) E. J. Cornish et al.   JOURNAL OF IMMUNOLOGY

Elevated Levels of the Neutrophil Chemoattractant Pro–Platelet Basic Protein in Macrophages From Individuals With Chronic and Allergic Aspergillosis

(2014) Nicola L. D. Smith et al.   JOURNAL OF INFECTIOUS DISEASES

Dectin-1–Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages

(2014) Jenny M. Tam et al.   JOURNAL OF INFECTIOUS DISEASES

ChIP-seq reveals a role for CrzA in theAspergillus fumigatushigh-osmolarity glycerol response (HOG) signalling pathway

(2014) Patrícia A. de Castro et al.   MOLECULAR MICROBIOLOGY

Neutrophil Responses to Aspergillosis: New Roles for Old Players

(2014) Cristina Cunha et al.   MYCOPATHOLOGIA

Calcineurin-Mediated Regulation of Hyphal Growth, Septation, and Virulence in Aspergillus fumigatus

(2014) Praveen R. Juvvadi et al.   MYCOPATHOLOGIA

A Biophysical Basis for Mucus Solids Concentration as a Candidate Biomarker for Airways Disease

(2014) David B. Hill et al.   PLoS One

Gene Expression Profiles of Human Dendritic Cells Interacting with Aspergillus fumigatus in a Bilayer Model of the Alveolar Epithelium/Endothelium Interface

(2014) Charles Oliver Morton et al.   PLoS One

pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37

(2014) Mahmoud H. Abou Alaiwa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis

(2014) M. J. Hoegger et al.   SCIENCE

Interference of Aspergillus fumigatus with the immune response

(2014) Thorsten Heinekamp et al.   Seminars in Immunopathology

The clinical spectrum of pulmonary aspergillosis

(2014) C. Kosmidis et al.   THORAX

Aspergillus fumigatus and Related Species

(2014) J. A. Sugui et al.   Cold Spring Harbor Perspectives in Medicine

The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis

(2014) Margherita Bertuzzi et al.   PLoS Pathogens

Inflammatory Monocytes Orchestrate Innate Antifungal Immunity in the Lung

(2014) Vanessa Espinosa et al.   PLoS Pathogens

Omalizumab: a new treatment option for allergic bronchopulmonary aspergillosis in patients with cystic fibrosis

(2014) Sylvia Lehmann et al.   Therapeutic Advances in Respiratory Disease

Macrophage Cytokines: Involvement in Immunity and Infectious Diseases

(2014) Guillermo Arango Duque et al.   Frontiers in Immunology

Fungal allergy in asthma–state of the art and research needs

(2014) David W Denning et al.   Clinical and Translational Allergy

Evaluation of intravenous voriconazole in patients with compromised renal function

(2013) Craig M Lilly et al.   BMC INFECTIOUS DISEASES

Long-term Antifungal Treatment Improves Health Status in Patients With Chronic Pulmonary Aspergillosis: A Longitudinal Analysis

(2013) Khaled Al-shair et al.   CLINICAL INFECTIOUS DISEASES

Aspergillus

(2013) Antonis Rokas   CURRENT BIOLOGY

Aspergillus fumigatus during stable state and exacerbations of COPD

(2013) M. Bafadhel et al.   EUROPEAN RESPIRATORY JOURNAL

IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

(2013) Andreas Schlitzer et al.   IMMUNITY

Role of Ficolin-A and Lectin Complement Pathway in the Innate Defense against Pathogenic Aspergillus Species

(2013) Stefan Bidula et al.   INFECTION AND IMMUNITY

Risk Factors for Invasive Pulmonary Aspergillosis and Hospital Mortality in Acute-On-Chronic Liver Failure Patients: A Retrospective-Cohort Study

(2013) Jiajia Chen et al.   International Journal of Medical Sciences

Dectin-1 Activation Controls Maturation of β-1,3-Glucan-containing Phagosomes

(2013) Michael K. Mansour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Results of surgery for chronic pulmonary Aspergillosis, optimal antifungal therapy and proposed high risk factors for recurrence - a National Centre’s experience

(2013) Shakil Farid et al.   Journal of Cardiothoracic Surgery

Monocyte- and Macrophage-Targeted NADPH Oxidase Mediates Antifungal Host Defense and Regulation of Acute Inflammation in Mice

(2013) M. J. Grimm et al.   JOURNAL OF IMMUNOLOGY

Pathogenesis and clinical features of chronic pulmonary aspergillosis – Is it possible to distinguish CNPA and CCPA clinically?

(2013) Koichi Izumikawa et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Chronic pulmonary aspergillosis

(2013) K. E. Schweer et al.   MYCOSES

Itraconazole in chronic cavitary pulmonary aspergillosis: a randomised controlled trial and systematic review of literature

(2013) Ritesh Agarwal et al.   MYCOSES

Activation of neutrophils by autocrine IL-17A–IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2

(2013) Patricia R Taylor et al.   NATURE IMMUNOLOGY

Human Genetic Susceptibility to Invasive Aspergillosis

(2013) Cristina Cunha et al.   PLoS Pathogens

Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune System

(2013) Fabrice N. Gravelat et al.   PLoS Pathogens

Aspergillus fumigatus—What Makes the Species a Ubiquitous Human Fungal Pathogen?

(2013) Kyung J. Kwon-Chung et al.   PLoS Pathogens

The Immune Interplay between the Host and the Pathogen inAspergillus fumigatusLung Infection

(2013) Helioswilton Sales-Campos et al.   Biomed Research International

The Effect ofAspergillus fumigatusInfection on Vitamin D Receptor Expression in Cystic Fibrosis

(2012) Catherine A. Coughlan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

(2012) Jørgen Vestbo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Aspergillusbronchitis without significant immunocompromise

(2012) Ales Chrdle et al.   Annals of the New York Academy of Sciences

Invasive aspergillosis in the intensive care unit

(2012) George Dimopoulos et al.   Annals of the New York Academy of Sciences

Tumor Necrosis Factor-α Signaling in Macrophages

(2012) Narayanan Parameswaran et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Invasive pulmonary aspergillosis is a frequent complication of critically ill H1N1 patients: a retrospective study

(2012) Joost Wauters et al.   INTENSIVE CARE MEDICINE

Voriconazole and Posaconazole Improve Asthma Severity in Allergic Bronchopulmonary Aspergillosis and Severe Asthma with Fungal Sensitization

(2012) Livingstone Chishimba et al.   JOURNAL OF ASTHMA

Hypoxia enhances innate immune activation to Aspergillus fumigatus through cell wall modulation

(2012) Kelly M. Shepardson et al.   MICROBES AND INFECTION

Current Understanding of HOG-MAPK Pathway in Aspergillus fumigatus

(2012) Dongmei Ma et al.   MYCOPATHOLOGIA

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

(2012) Alejandro A. Pezzulo et al.   NATURE

Treatment of Aspergillus fumigatus in Patients with Cystic Fibrosis: A Randomized, Placebo-Controlled Pilot Study

(2012) Shawn D. Aaron et al.   PLoS One

Cystic Fibrosis Transmembrane Conductance Regulator Regulates Epithelial Cell Response toAspergillusand Resultant Pulmonary Inflammation

(2011) Neelkamal Chaudhary et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Nonredundant Role for Plasmacytoid Dendritic Cells in Host Defense against the Human Fungal Pathogen Aspergillus fumigatus

(2011) Zaida G. Ramirez-Ortiz et al.   Cell Host & Microbe

The Diagnostic Value of Halo and Reversed Halo Signs for Invasive Mold Infections in Compromised Hosts

(2011) S. P. Georgiadou et al.   CLINICAL INFECTIOUS DISEASES

Comparison of an Aspergillus Real-time Polymerase Chain Reaction Assay With Galactomannan Testing of Bronchoalvelolar Lavage Fluid for the Diagnosis of Invasive Pulmonary Aspergillosis in Lung Transplant Recipients

(2011) M.-L. Luong et al.   CLINICAL INFECTIOUS DISEASES

Iron homeostasis—Achilles’ heel of Aspergillus fumigatus?

(2011) Markus Schrettl et al.   CURRENT OPINION IN MICROBIOLOGY

The role of Dectin-1 in the host defence against fungal infections

(2011) Rebecca A Drummond et al.   CURRENT OPINION IN MICROBIOLOGY

The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis

(2011) Frank L. van de Veerdonk et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Aspergillus fumigatus conidia induce interferon-  signalling in respiratory epithelial cells

(2011) C. Beisswenger et al.   EUROPEAN RESPIRATORY JOURNAL

Nutrient acquisition by pathogenic fungi: Nutrient availability, pathway regulation, and differences in substrate utilization

(2011) Christian B. Fleck et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Dectin-1 diversifiesAspergillus fumigatus–specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation

(2011) Amariliz Rivera et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Rapid Host Defense against Aspergillus fumigatus Involves Alveolar Macrophages with a Predominance of Alternatively Activated Phenotype

(2011) Shikha Bhatia et al.   PLoS One

The Temporal Dynamics of Differential Gene Expression in Aspergillus fumigatus Interacting with Human Immature Dendritic Cells In Vitro

(2011) Charles O. Morton et al.   PLoS One

β-1,3-Glucan-Induced Host Phospholipase D Activation Is Involved in Aspergillus fumigatus Internalization into Type II Human Pneumocyte A549 Cells

(2011) Xuelin Han et al.   PLoS One

HacA-Independent Functions of the ER Stress Sensor IreA Synergize with the Canonical UPR to Influence Virulence Traits in Aspergillus fumigatus

(2011) Xizhi Feng et al.   PLoS Pathogens

In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis

(2011) Nora Grahl et al.   PLoS Pathogens

Airborne Aspergillus fumigatus conidia: a risk factor for aspergillosis

(2011) Céline M. O’Gorman   Fungal Biology Reviews

Lack of Cystic Fibrosis Transmembrane Conductance Regulator in CD3+Lymphocytes Leads to Aberrant Cytokine Secretion and Hyperinflammatory Adaptive Immune Responses

(2010) Christian Mueller et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Signaling Functions of Reactive Oxygen Species

(2010) Henry Jay Forman et al.   BIOCHEMISTRY

Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity

(2010) C. Cunha et al.   BLOOD

Factors Associated with Mortality in Transplant Patients with Invasive Aspergillosis

(2010) John W. Baddley et al.   CLINICAL INFECTIOUS DISEASES

Rhinovirus induces MUC5AC in a human infection model and in vitro via NF- B and EGFR pathways

(2010) C. A. Hewson et al.   EUROPEAN RESPIRATORY JOURNAL

Underlying conditions in chronic pulmonary aspergillosis including simple aspergilloma

(2010) N. L. Smith et al.   EUROPEAN RESPIRATORY JOURNAL

Type of CFTR Mutation Determines Risk of Pancreatitis in Patients With Cystic Fibrosis

(2010) Chee Y. Ooi et al.   GASTROENTEROLOGY

Enhancement of anti-Aspergillus T helper type 1 response by interferon-β-conditioned dendritic cells

(2010) Valérie Gafa et al.   IMMUNOLOGY

AfMkk2 is required for cell wall integrity signaling, adhesion, and full virulence of the human pathogen Aspergillus fumigatus

(2010) Franziska Dirr et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Detection and investigation of invasive mould disease

(2010) M. Cuenca-Estrella et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The extracellular matrix at a glance

(2010) C. Frantz et al.   JOURNAL OF CELL SCIENCE

Alveolar inflammation in cystic fibrosis

(2010) Martina Ulrich et al.   Journal of Cystic Fibrosis

Neutropenia Enhances Lung Dendritic Cell Recruitment in Response to Aspergillus via a Cytokine-to-Chemokine Amplification Loop

(2010) S. J. Park et al.   JOURNAL OF IMMUNOLOGY

Aspergillushypersensitivity in patients with chronic obstructive pulmonary disease: COPD as a risk factor for ABPA?

(2010) Ritesh Agarwal et al.   MEDICAL MYCOLOGY

An inhalation model of airway allergic response to inhalation of environmentalAspergillus fumigatusconidia in sensitized BALB/c mice

(2010) Scott A. Hoselton et al.   MEDICAL MYCOLOGY

NETs formed by human neutrophils inhibit growth of the pathogenic mold Aspergillus fumigatus

(2010) Allison McCormick et al.   MICROBES AND INFECTION

Functional analysis of the superoxide dismutase family inAspergillus fumigatus

(2010) Karine Lambou et al.   MOLECULAR MICROBIOLOGY

What makes Aspergillus fumigatus a successful pathogen? Genes and molecules involved in invasive aspergillosis

(2010) Ana Abad et al.   REVISTA IBEROAMERICANA DE MICOLOGIA

Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA

(2010) Sandra Bruns et al.   PLoS Pathogens

Exploring temporal transcription regulation structure of Aspergillus fumigatus in heat shock by state space model

(2009) Jin Hwan Do et al.   BMC GENOMICS

Pulmonary aspergillosis in patients with chronic obstructive pulmonary disease: incidence, risk factors, and outcome

(2009) J. Guinea et al.   CLINICAL MICROBIOLOGY AND INFECTION

Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis

(2009) T. R. T. Dagenais et al.   CLINICAL MICROBIOLOGY REVIEWS

Activity of aminocandin (IP960; HMR3270) compared with amphotericin B, itraconazole, caspofungin and micafungin in neutropenic murine models of disseminated infection caused by itraconazole-susceptible and -resistant strains of Aspergillus fumigatus

(2009) Peter A. Warn et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Essential Role for Neutrophils but not Alveolar Macrophages at Early Time Points followingAspergillus fumigatusInfection

(2009) Monica M. Mircescu et al.   JOURNAL OF INFECTIOUS DISEASES

Viral Evasion of the Interferon System

(2009) Michael Gale et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

(2009) Olaf Gross et al.   NATURE

Transcriptomic analysis of the exit from dormancy of Aspergillus fumigatus conidia

(2008) Claude Lamarre et al.   BMC GENOMICS

Revised Definitions of Invasive Fungal Disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group

(2008) Ben De Pauw et al.   CLINICAL INFECTIOUS DISEASES

Contribution of Galactofuranose to the Virulence of the Opportunistic PathogenAspergillus fumigatus

(2008) Philipp S. Schmalhorst et al.   EUKARYOTIC CELL

The Putative α-1,2-Mannosyltransferase AfMnt1 of the Opportunistic Fungal PathogenAspergillus fumigatusIs Required for Cell Wall Stability and Full Virulence

(2008) Johannes Wagener et al.   EUKARYOTIC CELL

Aspergillus fumigatus-induced Interleukin-8 Synthesis by Respiratory Epithelial Cells Is Controlled by the Phosphatidylinositol 3-Kinase, p38 MAPK, and ERK1/2 Pathways and Not by the Toll-like Receptor-MyD88 Pathway

(2008) Viviane Balloy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

What do we know about the role of gliotoxin in the pathobiology ofAspergillus fumigatus?

(2008) Kyung J. Kwon-Chung et al.   MEDICAL MYCOLOGY

Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA

(2008) Frederico Marianetti Soriani et al.   MOLECULAR MICROBIOLOGY

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

(2008) Luigina Romani et al.   NATURE

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE

Treatment of allergic bronchopulmonary aspergillosis (ABPA) in CF with anti-IgE antibody (omalizumab)

(2008) Adaobi Kanu et al.   PEDIATRIC PULMONOLOGY

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

(2008) Sven D. Willger et al.   PLoS Pathogens