Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance

Worldwide emergence of resistance to antifungal drugs challenges human health and food security

(2018) Matthew C. Fisher et al.   SCIENCE

Aspergillus fumigatus morphology and dynamic host interactions

(2017) Frank L. van de Veerdonk et al.   NATURE REVIEWS MICROBIOLOGY

The contribution of Aspergillus fumigatus stress responses to virulence and antifungal resistance

(2016) Neil A. Brown et al.   JOURNAL OF MICROBIOLOGY

Mitogen activated protein kinases SakAHOG1and MpkC collaborate forAspergillus fumigatusvirulence

(2016) Ariane Cristina Mendes de Oliveira Bruder Nascimento et al.   MOLECULAR MICROBIOLOGY

Synergistic Effect of Fluconazole and Calcium Channel Blockers against Resistant Candida albicans

(2016) Shuyuan Liu et al.   PLoS One

Aspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway

(2016) K. L. Becker et al.   mBio

Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach

(2016) Praveen R. Juvvadi et al.   Virulence

The putative flavin carrier family FlcA-C is important for Aspergillus fumigatus virulence

(2016) Patrícia A. de Castro et al.   Virulence

Aspergillus fumigatus MADS-Box Transcription Factor rlmA Is Required for Regulation of the Cell Wall Integrity and Virulence

(2016) Marina Campos Rocha et al.   G3-Genes Genomes Genetics

Calcineurin Targets Involved in Stress Survival and Fungal Virulence

(2016) Hee-Soo Park et al.   PLoS Pathogens

Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus

(2015) Praveen R. Juvvadi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Caspofungin Treatment of Aspergillus fumigatus Results in ChsG-Dependent Upregulation of Chitin Synthesis and the Formation of Chitin-Rich Microcolonies

(2015) Louise A. Walker et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Potential Microbiological Effects of Higher Dosing of Echinocandins

(2015) William J. Steinbach et al.   CLINICAL INFECTIOUS DISEASES

The Aspergillus fumigatus sitA Phosphatase Homologue Is Important for Adhesion, Cell Wall Integrity, Biofilm Formation, and Virulence

(2015) Vinícius Leite Pedro Bom et al.   EUKARYOTIC CELL

Systematic gene deletion and functional characterization of histidine kinase phosphorelay receptors (HKRs) in the human pathogenic fungus Aspergillus fumigatus

(2015) F. Chapeland-Leclerc et al.   FUNGAL GENETICS AND BIOLOGY

Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species: Table 1.

(2015) Frédéric Lamoth et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

High osmolarity glycerol response PtcB phosphatase is important forAspergillus fumigatusvirulence

(2015) Lizziane K. Winkelströter et al.   MOLECULAR MICROBIOLOGY

Using RNA-Seq Data to Evaluate Reference Genes Suitable for Gene Expression Studies in Soybean

(2015) Aldrin Kay-Yuen Yim et al.   PLoS One

Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus

(2015) Lizziane K. Winkelströter et al.   G3-Genes Genomes Genetics

The Cryptococcus neoformans Alkaline Response Pathway: Identification of a Novel Rim Pathway Activator

(2015) Kyla S. Ost et al.   PLoS Genetics

The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence

(2015) Vito Valiante et al.   Frontiers in Microbiology

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Calcineurin-Crz1 Signaling in Lower Eukaryotes

(2014) S. Thewes   EUKARYOTIC CELL

The role of AtfA and HOG MAPK pathway in stress tolerance in conidia of Aspergillus fumigatus

(2014) Daisuke Hagiwara et al.   FUNGAL GENETICS AND BIOLOGY

ChIP-seq reveals a role for CrzA in theAspergillus fumigatushigh-osmolarity glycerol response (HOG) signalling pathway

(2014) Patrícia A. de Castro et al.   MOLECULAR MICROBIOLOGY

Up-date on Diagnostic Strategies of Invasive Aspergillosis

(2013) Michaela Lackner et al.   CURRENT PHARMACEUTICAL DESIGN

Overlapping and Distinct Roles ofAspergillus fumigatusUDP-glucose 4-Epimerases in Galactose Metabolism and the Synthesis of Galactose-containing Cell Wall Polysaccharides

(2013) Mark J. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

RSeQC: quality control of RNA-seq experiments

(2012) Liguo Wang et al.   BIOINFORMATICS

SortMeRNA: fast and accurate filtering of ribosomal RNAs in metatranscriptomic data

(2012) Evguenia Kopylova et al.   BIOINFORMATICS

Molecular Characterization of the Putative Transcription Factor SebA Involved in Virulence in Aspergillus fumigatus

(2012) Taísa Magnani Dinamarco et al.   EUKARYOTIC CELL

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Calcineurin Is Required for Pseudohyphal Growth, Virulence, and Drug Resistance in Candida lusitaniae

(2012) Jing Zhang et al.   PLoS One

Tackling Human Fungal Infections

(2012) G. D. Brown et al.   SCIENCE

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Calcineurin Controls Drug Tolerance, Hyphal Growth, and Virulence in Candida dubliniensis

(2011) Ying-Lien Chen et al.   EUKARYOTIC CELL

Generation of Mature Murine Monocytes from Heterogeneous Bone Marrow and Description of Their Properties

(2011) Alexander Francke et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Transcriptional Regulation of Chitin Synthases by Calcineurin Controls Paradoxical Growth of Aspergillus fumigatus in Response to Caspofungin

(2010) J. R. Fortwendel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of possible targets of the Aspergillus fumigatus CRZ1 homologue, CrzA

(2010) Frederico M Soriani et al.   BMC MICROBIOLOGY

In vitro interaction of posaconazole with calcineurin inhibitors and sirolimus against zygomycetes

(2010) S. Narreddy et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans

(2009) Piet W.J. de Groot et al.   FUNGAL GENETICS AND BIOLOGY

The nsdC Gene Encoding a Putative C2H2-Type Transcription Factor Is a Key Activator of Sexual Development in Aspergillus nidulans

(2009) H.-R. Kim et al.   GENETICS

TLR2 Is a Negative Regulator of Th17 Cells and Tissue Pathology in a Pulmonary Model of Fungal Infection

(2009) F. V. Loures et al.   JOURNAL OF IMMUNOLOGY

The innate immune response to Aspergillus fumigatus

(2009) Viviane Balloy et al.   MICROBES AND INFECTION

Two zinc finger transcription factors, CrzA and SltA, are involved in cation homoeostasis and detoxification inAspergillus nidulans

(2008) Anja Spielvogel et al.   BIOCHEMICAL JOURNAL

Calcineurin Target CrzA Regulates Conidial Germination, Hyphal Growth, and Pathogenesis ofAspergillus fumigatus

(2008) Robert A. Cramer et al.   EUKARYOTIC CELL

Th17 cells in the setting ofAspergillusinfection and pathology

(2008) Teresa Zelante et al.   MEDICAL MYCOLOGY

Hsp90-Dependent Activation of Protein Kinases Is Regulated by Chaperone-Targeted Dephosphorylation of Cdc37

(2008) Cara K. Vaughan et al.   MOLECULAR CELL

Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA

(2008) Frederico Marianetti Soriani et al.   MOLECULAR MICROBIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Bursting into the Nucleus

(2008) G. R. Crabtree et al.   Science Signaling