IL-1α Signaling Is Critical for Leukocyte Recruitment after Pulmonary Aspergillus fumigatus Challenge

Acidosis Potentiates the Host Proinflammatory Interleukin-1β Response to Pseudomonas aeruginosa Infection

(2014) Iviana M. Torres et al.   INFECTION AND IMMUNITY

Release of Interleukin-1α or Interleukin-1β Depends on Mechanism of Cell Death

(2014) Hazel England et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCL1 Contributes to Host Defense in Polymicrobial Sepsis via Modulating T Cell and Neutrophil Functions

(2014) Liliang Jin et al.   JOURNAL OF IMMUNOLOGY

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

(2014) Antonella de Luca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

Myeloid Derived Hypoxia Inducible Factor 1-alpha Is Required for Protection against Pulmonary Aspergillus fumigatus Infection

(2014) Kelly M. Shepardson et al.   PLoS Pathogens

A Polysaccharide Virulence Factor from Aspergillus fumigatus Elicits Anti-inflammatory Effects through Induction of Interleukin-1 Receptor Antagonist

(2014) Mark S. Gresnigt et al.   PLoS Pathogens

Inflammatory Monocytes Orchestrate Innate Antifungal Immunity in the Lung

(2014) Vanessa Espinosa et al.   PLoS Pathogens

Biofilm from a clinical strain of Cryptococcus neoformans activates the NLRP3 inflammasome

(2013) Guowei Lei et al.   CELL RESEARCH

Azole resistance in Aspergillus fumigatus

(2013) Edith Vermeulen et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Frequency, diagnosis and management of fungal respiratory infections

(2013) Gemma E. Hayes et al.   CURRENT OPINION IN PULMONARY MEDICINE

Intracellular Interleukin-1 Receptor 2 Binding Prevents Cleavage and Activity of Interleukin-1α, Controlling Necrosis-Induced Sterile Inflammation

(2013) Yue Zheng et al.   IMMUNITY

The Interleukin-1 Family: Back to the Future

(2013) Cecilia Garlanda et al.   IMMUNITY

Pathogenic Fungus Microsporum canis Activates the NLRP3 Inflammasome

(2013) Liming Mao et al.   INFECTION AND IMMUNITY

IL-1  Signaling Initiates the Inflammatory Response to Virulent Legionella pneumophila In Vivo

(2013) K. C. Barry et al.   JOURNAL OF IMMUNOLOGY

Strain Dependent Variation of Immune Responses to A. fumigatus: Definition of Pathogenic Species

(2013) Lisa Rizzetto et al.   PLoS One

NLRP3 Inflammasome Activation by Paracoccidioides brasiliensis

(2013) Aldo Henrique Tavares et al.   PLoS Neglected Tropical Diseases

Infections associated with chronic granulomatous disease: linking genetics to phenotypic expression

(2012) Josef Ben-Ari et al.   Expert Review of Anti-Infective Therapy

Transepithelial migration of neutrophils into the lung requires TREM-1

(2012) Julia Klesney-Tait et al.   JOURNAL OF CLINICAL INVESTIGATION

Intrapulmonary Administration of Leukotriene B4 Augments Neutrophil Accumulation and Responses in the Lung to Klebsiella Infection in CXCL1 Knockout Mice

(2012) S. Batra et al.   JOURNAL OF IMMUNOLOGY

Hypoxia enhances innate immune activation to Aspergillus fumigatus through cell wall modulation

(2012) Kelly M. Shepardson et al.   MICROBES AND INFECTION

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Tracing Conidial Fate and Measuring Host Cell Antifungal Activity Using a Reporter of Microbial Viability in the Lung

(2012) Anupam Jhingran et al.   Cell Reports

A Nonredundant Role for Plasmacytoid Dendritic Cells in Host Defense against the Human Fungal Pathogen Aspergillus fumigatus

(2011) Zaida G. Ramirez-Ortiz et al.   Cell Host & Microbe

Innate Recognition of Cell Wall β-Glucans Drives Invariant Natural Killer T Cell Responses against Fungi

(2011) Nadia R. Cohen et al.   Cell Host & Microbe

Immune responses against Aspergillus fumigatus

(2011) Robert A. Cramer et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Innate and Adaptive Interferons Suppress IL-1α and IL-1β Production by Distinct Pulmonary Myeloid Subsets during Mycobacterium tuberculosis Infection

(2011) Katrin D. Mayer-Barber et al.   IMMUNITY

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Aspergillosis in the ‘Nonimmunocompromised’ Host

(2011) David A. Stevens et al.   IMMUNOLOGICAL INVESTIGATIONS

Nonhematopoietic Cells Are Key Players in Innate Control of Bacterial Airway Infection

(2011) S. LeibundGut-Landmann et al.   JOURNAL OF IMMUNOLOGY

IL-1  and IL-1  Recruit Different Myeloid Cells and Promote Different Stages of Sterile Inflammation

(2011) P. Rider et al.   JOURNAL OF IMMUNOLOGY

A Novel Role for the NLRC4 Inflammasome in Mucosal Defenses against the Fungal Pathogen Candida albicans

(2011) Jeffrey Tomalka et al.   PLoS Pathogens

In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis

(2011) Nora Grahl et al.   PLoS Pathogens

Aspergillus fumigatus Stimulates the NLRP3 Inflammasome through a Pathway Requiring ROS Production and the Syk Tyrosine Kinase

(2010) Najwane Saïd-Sadier et al.   PLoS One

Reactive oxygen species-independent activation of the IL-1  inflammasome in cells from patients with chronic granulomatous disease

(2010) F. L. van de Veerdonk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Roles for Dectin-1 and TLR4 in the Pathogenesis of Aspergillus fumigatus Keratitis

(2010) Sixto M. Leal et al.   PLoS Pathogens

Polymorphism in a gene coding for the inflammasome component NALP3 and recurrent vulvovaginal candidiasis in women with vulvar vestibulitis syndrome

(2009) Ahinoam Lev-Sagie et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Inflammatory Monocytes Facilitate Adaptive CD4 T Cell Responses during Respiratory Fungal Infection

(2009) Tobias M. Hohl et al.   Cell Host & Microbe

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans

(2009) Amy G. Hise et al.   Cell Host & Microbe

Innate Immunity to Aspergillus Species

(2009) S. J. Park et al.   CLINICAL MICROBIOLOGY REVIEWS

Selective Expansion of the Monocytic Lineage Directed by Bacterial Infection

(2009) N. V. Serbina et al.   JOURNAL OF IMMUNOLOGY

Requisite Role for the Dectin-1  -Glucan Receptor in Pulmonary Defense against Aspergillus fumigatus

(2009) J. L. Werner et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the Nlrp3 Inflammasome

(2009) S. Joly et al.   JOURNAL OF IMMUNOLOGY

Essential Role for Neutrophils but not Alveolar Macrophages at Early Time Points followingAspergillus fumigatusInfection

(2009) Monica M. Mircescu et al.   JOURNAL OF INFECTIOUS DISEASES

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

(2009) Olaf Gross et al.   NATURE

Aspergillosis

(2009) Brahm H. Segal   NEW ENGLAND JOURNAL OF MEDICINE

IL1 Gene Cluster Polymorphisms and Its Haplotypes may Predict the Risk to Develop Invasive Pulmonary Aspergillosis and Modulate C-reactive Protein Level

(2008) J. Sainz et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Invasive aspergillosis in glucocorticoid-treated patients

(2008) Russell E. Lewis et al.   MEDICAL MYCOLOGY