Dual mechanisms of cholesterol-GPCR interactions that depend on membrane phospholipid composition
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Dual mechanisms of cholesterol-GPCR interactions that depend on membrane phospholipid composition
Authors
Keywords
-
Journal
STRUCTURE
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2023-05-25
DOI
10.1016/j.str.2023.05.001
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Allosteric modulation of the adenosine A2A receptor by cholesterol
- (2022) Shuya Kate Huang et al. eLife
- Cholesterol Dependent Activity of the Adenosine A2A Receptor Is Modulated via the Cholesterol Consensus Motif
- (2022) Claire McGraw et al. MOLECULES
- The oxytocin signaling complex reveals a molecular switch for cation dependence
- (2022) Justin G. Meyerowitz et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Filling of a water-free void explains the allosteric regulation of the β1-adrenergic receptor by cholesterol
- (2022) Layara Akemi Abiko et al. Nature Chemistry
- Activation of the human chemokine receptor CX3CR1 regulated by cholesterol
- (2022) Minmin Lu et al. Science Advances
- Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking
- (2022) Nycole Maza et al. NATURE NEUROSCIENCE
- Allosteric Modulation of GPCRs of Class A by Cholesterol
- (2021) Jan Jakubík et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cholesterol as a modulator of cannabinoid receptor CB2 signaling
- (2021) Alexei Yeliseev et al. Scientific Reports
- Delineating the conformational landscape of the adenosine A2A receptor during G protein coupling
- (2021) Shuya Kate Huang et al. CELL
- Predictable cholesterol binding sites in GPCRs lack consensus motifs
- (2021) Geoffrey J. Taghon et al. STRUCTURE
- Mechanisms of selective G protein–coupled receptor localization and trafficking
- (2021) Jennifer M. Kunselman et al. CURRENT OPINION IN CELL BIOLOGY
- A molecular sensor for cholesterol in the human serotonin1A receptor
- (2021) G. Aditya Kumar et al. Science Advances
- Cholesterol Is a Dose-Dependent Positive Allosteric Modulator of CCR3 Ligand Affinity and G Protein Coupling
- (2021) Evan van Aalst et al. Frontiers in Molecular Biosciences
- Slow conformational dynamics of the human A2A adenosine receptor are temporally ordered
- (2021) Shushu Wei et al. STRUCTURE
- Cholesterol interaction motifs in G protein-coupled receptors: Slippery hot spots?
- (2020) Parijat Sarkar et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Activation of adenosine A2A receptor by lipids from docosahexaenoic acid revealed by NMR
- (2020) Takuya Mizumura et al. Science Advances
- Erg6 affects membrane composition and virulence of the human fungal pathogen Cryptococcus neoformans
- (2020) Fabiana Freire M. Oliveira et al. FUNGAL GENETICS AND BIOLOGY
- A2A Adenosine Receptor Partial Agonism Related to Structural Rearrangements in an Activation Microswitch
- (2020) Matthew T. Eddy et al. STRUCTURE
- Membrane cholesterol depletion reduces downstream signaling activity of the adenosine A2a receptor
- (2019) Claire McGraw et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Cholesterol metabolism, pancreatic β-cell function and diabetes
- (2019) Carla Perego et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity
- (2019) Linda C. Johansson et al. NATURE
- Structural basis of ligand recognition at the human MT1 melatonin receptor
- (2019) Benjamin Stauch et al. NATURE
- 24S-Hydroxycholesterol Is Associated with Agitation Severity in Patients with Moderate-to-Severe Alzheimer’s Disease: Analyses from a Clinical Trial with Nabilone
- (2019) Myuri Ruthirakuhan et al. JOURNAL OF ALZHEIMERS DISEASE
- Smoothened stimulation by membrane sterols drives Hedgehog pathway activity
- (2019) Ishan Deshpande et al. NATURE
- Lipid-Dependent Regulation of Ion Channels and G Protein–Coupled Receptors: Insights from Structures and Simulations
- (2019) Anna L. Duncan et al. Annual Review of Pharmacology and Toxicology
- Reconstruction of apo A2A receptor activation pathways reveal ligand-competent intermediates and state-dependent cholesterol hotspots
- (2019) Silvia Lovera et al. Scientific Reports
- Statin-Induced Chronic Cholesterol Depletion Switches GPCR Endocytosis and Trafficking: Insights from the Serotonin1A Receptor
- (2019) G. Aditya Kumar et al. ACS Chemical Neuroscience
- Cholesterol impacts chemokine CCR5 receptor ligand‐binding activity
- (2019) Pierre Calmet et al. FEBS Journal
- Allosteric Coupling of Drug Binding and Intracellular Signaling in the A 2A Adenosine Receptor
- (2018) Matthew T. Eddy et al. CELL
- Disease-Causing Mutations in the G Protein Gαs Subvert the Roles of GDP and GTP
- (2018) Qi Hu et al. CELL
- Extrinsic Tryptophans as NMR Probes of Allosteric Coupling in Membrane Proteins: Application to the A2A Adenosine Receptor
- (2018) Matthew T. Eddy et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Understanding the diversity of membrane lipid composition
- (2018) Takeshi Harayama et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling
- (2018) Kate L. White et al. STRUCTURE
- Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein
- (2018) Javier García-Nafría et al. eLife
- A2A adenosine receptor functional states characterized by 19F-NMR
- (2018) Lukas Sušac et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Coupled Receptor Smoothened
- (2018) George Hedger et al. STRUCTURE
- State-dependent Lipid Interactions with the A2a Receptor Revealed by MD Simulations Using In Vivo-Mimetic Membranes
- (2018) Wanling Song et al. STRUCTURE
- Assembly of phospholipid nanodiscs of controlled size for structural studies of membrane proteins by NMR
- (2017) Franz Hagn et al. Nature Protocols
- Trends in GPCR drug discovery: new agents, targets and indications
- (2017) Alexander S. Hauser et al. NATURE REVIEWS DRUG DISCOVERY
- Cholesterol-binding site of the influenza M2 protein in lipid bilayers from solid-state NMR
- (2017) Matthew R. Elkins et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Membrane cholesterol access into a G-protein-coupled receptor
- (2017) Ramon Guixà-González et al. Nature Communications
- Co-inhibition of CD73 and A2AR Adenosine Signaling Improves Anti-tumor Immune Responses
- (2016) Arabella Young et al. CANCER CELL
- Structure of the adenosine A2A receptor bound to an engineered G protein
- (2016) Byron Carpenter et al. NATURE
- Activation of the A2A adenosine G-protein-coupled receptor by conformational selection
- (2016) Libin Ye et al. NATURE
- Cholesterol-dependent Conformational Plasticity in GPCR Dimers
- (2016) Xavier Prasanna et al. Scientific Reports
- Dynamic Cholesterol-Conditioned Dimerization of the G Protein Coupled Chemokine Receptor Type 4
- (2016) Kristyna Pluhackova et al. PLoS Computational Biology
- Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling
- (2016) Giovanni Luchetti et al. eLife
- In-Membrane Chemical Modification (IMCM) for Site-Specific Chromophore Labeling of GPCRs
- (2015) Lukas Sušac et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Homogenous Bioluminescent System for Measuring GTPase, GTPase Activating Protein, and Guanine Nucleotide Exchange Factor Activities
- (2015) Subhanjan Mondal et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- The influence of cholesterol on membrane protein structure, function, and dynamics studied by molecular dynamics simulations
- (2015) Julie Grouleff et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Molecular Model for the Solubilization of Membranes into Nanodisks by Styrene Maleic Acid Copolymers
- (2015) Stefan Scheidelaar et al. BIOPHYSICAL JOURNAL
- A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins
- (2015) Joseph L. Goldstein et al. CELL
- Excitements and Challenges in GPCR Oligomerization: Molecular Insight from FRET
- (2014) Hirak Chakraborty et al. ACS Chemical Neuroscience
- Two Classes of Cholesterol Binding Sites for the β 2 AR Revealed by Thermostability and NMR
- (2014) Deborah L. Gater et al. BIOPHYSICAL JOURNAL
- Non-covalent binding of membrane lipids to membrane proteins
- (2013) Philip L. Yeagle BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Ligand-dependent cholesterol interactions with the human A2A adenosine receptor
- (2013) Ji Young Lee et al. CHEMISTRY AND PHYSICS OF LIPIDS
- Cholesterol as a co-solvent and a ligand for membrane proteins
- (2013) Yuanli Song et al. PROTEIN SCIENCE
- Structural Features for Functional Selectivity at Serotonin Receptors
- (2013) D. Wacker et al. SCIENCE
- How cholesterol interacts with membrane proteins: an exploration of cholesterol-binding sites including CRAC, CARC, and tilted domains
- (2013) Jacques Fantini et al. Frontiers in Physiology
- Membrane cholesterol stabilizes the human serotonin1A receptor
- (2012) Roopali Saxena et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions
- (2012) W. Liu et al. SCIENCE
- Uncovering the intimate relationship between lipids, cholesterol and GPCR activation
- (2011) Joanne Oates et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
- (2011) Guillaume Lebon et al. NATURE
- Linking lipids to Alzheimer's disease: cholesterol and beyond
- (2011) Gilbert Di Paolo et al. NATURE REVIEWS NEUROSCIENCE
- Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist
- (2010) E. Y. T. Chien et al. SCIENCE
- The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
- (2008) V.-P. Jaakola et al. SCIENCE
- Microscale Fluorescent Thermal Stability Assay for Membrane Proteins
- (2008) Alexander I. Alexandrov et al. STRUCTURE
- A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor
- (2008) Michael A. Hanson et al. STRUCTURE
- Stabilization of the Human β2-Adrenergic Receptor TM4–TM3–TM5 Helix Interface by Mutagenesis of Glu1223.41, A Critical Residue in GPCR Structure
- (2007) Christopher B. Roth et al. JOURNAL OF MOLECULAR BIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started