In-Membrane Chemical Modification (IMCM) for Site-Specific Chromophore Labeling of GPCRs

Structural Insights into the Dynamic Process of β 2 -Adrenergic Receptor Signaling

(2015) Aashish Manglik et al.   CELL

Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes

(2014) Signe Mathiasen et al.   NATURE METHODS

β2-Adrenergic Receptor Activation by Agonists Studied with19F NMR Spectroscopy

(2013) Reto Horst et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine-19 NMR of integral membrane proteins illustrated with studies of GPCRs

(2013) Tatiana Didenko et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Role of Ligands on the Equilibria Between Functional States of a G Protein-Coupled Receptor

(2013) Tae Hun Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Role of Detergents in Conformational Exchange of a G Protein-coupled Receptor

(2012) Ka Young Chung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Key Agonist-induced Conformational Change in the Cannabinoid Receptor CB1 Is Blocked by the Allosteric Ligand Org 27569

(2012) Jonathan F. Fay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the human κ-opioid receptor in complex with JDTic

(2012) Huixian Wu et al.   NATURE

Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy

(2012) R. Rahmeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

(2012) W. Liu et al.   SCIENCE

Biased Signaling Pathways in  2-Adrenergic Receptor Characterized by 19F-NMR

(2012) J. J. Liu et al.   SCIENCE

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

(2011) Guillaume Lebon et al.   NATURE

Structure of an Agonist-Bound Human A2A Adenosine Receptor

(2011) F. Xu et al.   SCIENCE

Site-specific labeling of proteins with NMR-active unnatural amino acids

(2009) David H. Jones et al.   JOURNAL OF BIOMOLECULAR NMR

The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist

(2008) V.-P. Jaakola et al.   SCIENCE