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XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity

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Serial Femtosecond Crystallography of G Protein–Coupled Receptors

(2018) Benjamin Stauch et al.   Annual Review of Biophysics

5-HT 2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology

(2018) Yao Peng et al.   CELL

Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling

(2018) Kate L. White et al.   STRUCTURE

Structural basis for selectivity and diversity in angiotensin II receptors

(2017) Haitao Zhang et al.   NATURE

Update on melatonin receptors: IUPHAR Review 20

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Melatonin receptors as therapeutic targets in the suprachiasmatic nucleus

(2016) Paul Pévet   EXPERT OPINION ON THERAPEUTIC TARGETS

UniProt: the universal protein knowledgebase

(2016)   NUCLEIC ACIDS RESEARCH

Recent developments inCrystFEL

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Novel N-Acetyl Bioisosteres of Melatonin: Melatonergic Receptor Pharmacology, Physicochemical Studies, and Phenotypic Assessment of Their Neurogenic Potential

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GPCRdb: an information system for G protein-coupled receptors

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(2015) Vignir Isberg et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Understanding melatonin receptor pharmacology: Latest insights from mouse models, and their relevance to human disease

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CAVER Analyst 1.0: graphic tool for interactive visualization and analysis of tunnels and channels in protein structures

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Agomelatine: mechanism of action and pharmacological profile in relation to antidepressant properties

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Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant

(2014) Jie Yin et al.   NATURE

Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography

(2014) Wei Liu et al.   Nature Protocols

Allosteric sodium in class A GPCR signaling

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Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

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Cheetah: software for high-throughput reduction and analysis of serial femtosecond X-ray diffraction data

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The ChEMBL bioactivity database: an update

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Serial Femtosecond Crystallography of G Protein-Coupled Receptors

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Recent Progress in the Development of Agonists and Antagonists for Melatonin Receptors

(2012) D. P. Zlotos   CURRENT MEDICINAL CHEMISTRY

CrystFEL: a software suite for snapshot serial crystallography

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Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

OPM database and PPM web server: resources for positioning of proteins in membranes

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(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

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The Coherent X-ray Imaging (CXI) instrument at the Linac Coherent Light Source (LCLS)

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International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors

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MolProbity: all-atom structure validation for macromolecular crystallography

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Biopython: freely available Python tools for computational molecular biology and bioinformatics

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Thermostabilization of the Neurotensin Receptor NTS1

(2009) Yoko Shibata et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystallizing membrane proteins using lipidic mesophases

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CHARMM-GUI: A web-based graphical user interface for CHARMM

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Agonist-Induced Conformational Changes in Bovine Rhodopsin: Insight into Activation of G-Protein-Coupled Receptors

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NCBI BLAST: a better web interface

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Microscale Fluorescent Thermal Stability Assay for Membrane Proteins

(2008) Alexander I. Alexandrov et al.   STRUCTURE

Stabilization of the Human β2-Adrenergic Receptor TM4–TM3–TM5 Helix Interface by Mutagenesis of Glu1223.41, A Critical Residue in GPCR Structure

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