Assembly of phospholipid nanodiscs of controlled size for structural studies of membrane proteins by NMR

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

(2016) Yuan Gao et al.   NATURE

Covalently circularized nanodiscs for studying membrane proteins and viral entry

(2016) Mahmoud L Nasr et al.   NATURE METHODS

Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I

(2016) Stefan Bibow et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conformational dynamics of a G-protein α subunit is tightly regulated by nucleotide binding

(2016) David Goricanec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of the membrane-inserted C-terminus of cytoprotective BCL-XL

(2016) Yong Yao et al.   PROTEIN EXPRESSION AND PURIFICATION

Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I

(2016) Stefan Bibow et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Solid-state NMR of the Yersinia pestis outer membrane protein Ail in lipid bilayer nanodiscs sedimented by ultracentrifugation

(2015) Yi Ding et al.   JOURNAL OF BIOMOLECULAR NMR

Characterization of the insertase BamA in three different membrane mimetics by solution NMR spectroscopy

(2015) Leonor Morgado et al.   JOURNAL OF BIOMOLECULAR NMR

Optimizing nanodiscs and bicelles for solution NMR studies of two β-barrel membrane proteins

(2015) Iga Kucharska et al.   JOURNAL OF BIOMOLECULAR NMR

Conformation of BCL-XL upon Membrane Integration

(2015) Yong Yao et al.   JOURNAL OF MOLECULAR BIOLOGY

Exocytotic fusion pores are composed of both lipids and proteins

(2015) Huan Bao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Inside-out Ca2+ signalling prompted by STIM1 conformational switch

(2015) Guolin Ma et al.   Nature Communications

Exocytotic fusion pores are composed of both lipids and proteins

(2015) Huan Bao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single-particle electron microscopy in the study of membrane protein structure

(2015) Rita De Zorzi et al.   Microscopy

Solution-NMR Characterization of Outer-Membrane Protein A fromE. coliin Lipid Bilayer Nanodiscs and Detergent Micelles

(2014) Lukas Sušac et al.   CHEMBIOCHEM

An Annular Lipid Belt Is Essential for Allosteric Coupling and Viral Inhibition of the Antigen Translocation Complex TAP (Transporter Associated with Antigen Processing)

(2014) Sabine Eggensperger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure refinement and membrane positioning of selectively labeled OmpX in phospholipid nanodiscs

(2014) Franz Hagn et al.   JOURNAL OF BIOMOLECULAR NMR

Measuring membrane protein bond orientations in nanodiscs via residual dipolar couplings

(2014) Stefan Bibow et al.   PROTEIN SCIENCE

Membrane-Dependent Modulation of the mTOR Activator Rheb: NMR Observations of a GTPase Tethered to a Lipid-Bilayer Nanodisc

(2013) Mohammad T. Mazhab-Jafari et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins

(2013) Franz Hagn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional studies of N-terminally modified CYP2J2 epoxygenase in model lipid bilayers

(2013) Daniel R. McDougle et al.   PROTEIN SCIENCE

Cell-free Expressed Bacteriorhodopsin in Different Soluble Membrane Mimetics: Biophysical Properties and NMR Accessibility

(2013) Manuel Etzkorn et al.   STRUCTURE

Lipid–protein nanodiscs promote in vitro folding of transmembrane domains of multi-helical and multimeric membrane proteins

(2012) Zakhar O. Shenkarev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Modified lipid and protein dynamics in nanodiscs

(2012) Karsten Mörs et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Exploring signal-to-noise ratio and sensitivity in non-uniformly sampled multi-dimensional NMR spectra

(2012) Sven G. Hyberts et al.   JOURNAL OF BIOMOLECULAR NMR

Application of iterative soft thresholding for fast reconstruction of NMR data non-uniformly sampled with multidimensional Poisson Gap scheduling

(2012) Sven G. Hyberts et al.   JOURNAL OF BIOMOLECULAR NMR

Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscs

(2011) Tsyr-Yan Yu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Recent contributions from solid-state NMR to the understanding of membrane protein structure and function

(2011) Peter J Judge et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A simple biosynthetic method for stereospecific resonance assignment of prochiral methyl groups in proteins

(2011) Michael J. Plevin et al.   JOURNAL OF BIOMOLECULAR NMR

Conformational Transitions in the Membrane Scaffold Protein of Phospholipid Bilayer Nanodiscs

(2011) Christopher R. Morgan et al.   MOLECULAR & CELLULAR PROTEOMICS

Stereospecific Isotopic Labeling of Methyl Groups for NMR Spectroscopic Studies of High-Molecular-Weight Proteins

(2010) Pierre Gans et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Poisson-Gap Sampling and Forward Maximum Entropy Reconstruction for Enhancing the Resolution and Sensitivity of Protein NMR Data

(2010) Sven G. Hyberts et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The structure of the integrin αIIbβ3 transmembrane complex explains integrin transmembrane signalling

(2009) Tong-Lay Lau et al.   EMBO JOURNAL

Membrane protein assembly into Nanodiscs

(2009) Timothy H. Bayburt et al.   FEBS LETTERS

An efficient protocol for the complete incorporation of methyl-protonated alanine in perdeuterated protein

(2009) Isabel Ayala et al.   JOURNAL OF BIOMOLECULAR NMR

Structural and Functional Characterization of the Integral Membrane Protein VDAC-1 in Lipid Bilayer Nanodiscs

(2009) Thomas Raschle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystallizing membrane proteins using lipidic mesophases

(2009) Martin Caffrey et al.   Nature Protocols

Crystallizing Membrane Proteins for Structure Determination: Use of Lipidic Mesophases

(2008) Martin Caffrey   Annual Review of Biophysics

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Insights from biophysical studies on the role of polyunsaturated fatty acids for function of G-protein coupled membrane receptors

(2008) Klaus Gawrisch et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS