Non-canonical helical transitions and conformational switching are associated with characteristic flexibility and disorder indices in TRP and Kv channels
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Non-canonical helical transitions and conformational switching are associated with characteristic flexibility and disorder indices in TRP and Kv channels
Authors
Keywords
-
Journal
Channels
Volume 17, Issue 1, Pages -
Publisher
Informa UK Limited
Online
2023-05-18
DOI
10.1080/19336950.2023.2212349
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Peptide Flexibility and the Hydrophobic Moment are Determinants to Evaluate the Clinical Potential of Magainins
- (2023) Daniel Balleza JOURNAL OF MEMBRANE BIOLOGY
- TRPC3 channel gating by lipids requires localization at the ER/PM junctions defined by STIM1
- (2022) Haiping Liu et al. JOURNAL OF CELL BIOLOGY
- Structures of a mammalian TRPM8 in closed state
- (2022) Cheng Zhao et al. Nature Communications
- Structural basis of TRPV3 inhibition by an antagonist
- (2022) Junping Fan et al. Nature Chemical Biology
- Unstructural Biology of TRP Ion Channels: The Role of Intrinsically Disordered Regions in Channel Function and Regulation
- (2021) Benedikt Goretzki et al. JOURNAL OF MOLECULAR BIOLOGY
- Extracellular cap domain is an essential component of the TRPV1 gating mechanism
- (2021) Kirill D. Nadezhdin et al. Nature Communications
- Heat-dependent opening of TRPV1 in the presence of capsaicin
- (2021) Do Hoon Kwon et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Principal component analysis of alpha-helix deformations in transmembrane proteins
- (2021) Alexander Bevacqua et al. PLoS One
- A specialized pore turret in the mammalian cation channel TRPV1 is responsible for distinct and species-specific heat activation thresholds
- (2020) Guangxu Du et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Irritant-evoked activation and calcium modulation of the TRPA1 receptor
- (2020) Jianhua Zhao et al. NATURE
- Autoinhibition of TRPV6 channel and regulation by PIP2
- (2020) Ruiqi Cai et al. iScience
- Evidence that the TRPV1 S1-S4 membrane domain contributes to thermosensing
- (2020) Minjoo Kim et al. Nature Communications
- Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms
- (2020) Katherine E Huffer et al. eLife
- Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel
- (2019) Ying Yin et al. SCIENCE
- Utility of B-Factors in Protein Science: Interpreting Rigidity, Flexibility, and Internal Motion and Engineering Thermostability
- (2019) Zhoutong Sun et al. CHEMICAL REVIEWS
- PiPred – a deep-learning method for prediction of π-helices in protein sequences
- (2019) Jan Ludwiczak et al. Scientific Reports
- Metal bridge in S4 segment supports helix transition in Shaker channel
- (2019) Carlos A.Z. Bassetto et al. BIOPHYSICAL JOURNAL
- Extramembranous Regions in G Protein-Coupled Receptors: Cinderella in Receptor Biology?
- (2019) Sreetama Pal et al. JOURNAL OF MEMBRANE BIOLOGY
- Structural insights into TRPM8 inhibition and desensitization
- (2019) Melinda M. Diver et al. SCIENCE
- Molecular mechanism of TRPV2 channel modulation by cannabidiol
- (2019) Ruth A Pumroy et al. eLife
- The role of π-helices in TRP channel gating
- (2019) Lejla Zubcevic et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel
- (2019) Yang Suo et al. NEURON
- Dynamics and deformability of α-, 310- and π-helices
- (2018) Tarun Narwani et al. Archives of Biological Sciences
- Structure of the receptor-activated human TRPC6 and TRPC3 ion channels
- (2018) Qinglin Tang et al. CELL RESEARCH
- Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms
- (2018) Zengqin Deng et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Conformational plasticity in the selectivity filter of the TRPV2 ion channel
- (2018) Lejla Zubcevic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM
- (2018) Taylor E. T. Hughes et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Dawning of a new era in TRP channel structural biology by cryo-electron microscopy
- (2018) M. Gregor Madej et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Structure of full-length human TRPM4
- (2018) Jingjing Duan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms
- (2018) Zengqin Deng et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Conformational plasticity in the selectivity filter of the TRPV2 ion channel
- (2018) Lejla Zubcevic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM
- (2018) Taylor E. T. Hughes et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure of the human PKD1-PKD2 complex
- (2018) Qiang Su et al. SCIENCE
- A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine
- (2018) Marina A. Kasimova et al. JOURNAL OF GENERAL PHYSIOLOGY
- Structures of TRPV2 in distinct conformations provide insight into role of the pore turret
- (2018) Timothy L. Dosey et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- TRPV1 pore turret dictates distinct DkTx and capsaicin gating
- (2018) Matan Geron et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Conformational ensemble of the human TRPV3 ion channel
- (2018) Lejla Zubcevic et al. Nature Communications
- Electron cryo-microscopy structure of the mechanotransduction channel NOMPC
- (2017) Peng Jin et al. NATURE
- Structure of mammalian endolysosomal TRPML1 channel in nanodiscs
- (2017) Qingfeng Chen et al. NATURE
- Opening of the human epithelial calcium channel TRPV6
- (2017) Luke L. McGoldrick et al. NATURE
- Structural basis of dual Ca2+/pH regulation of the endolysosomal TRPML1 channel
- (2017) Minghui Li et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Side chain flexibility and coupling between the S4-S5 linker and the TRP domain in thermo-sensitive TRP channels: Insights from protein modeling
- (2017) Sergio Romero-Romero et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Structure of the cold- and menthol-sensing ion channel TRPM8
- (2017) Ying Yin et al. SCIENCE
- Structure of the human TRPM4 ion channel in a lipid nanodisc
- (2017) Henriette E. Autzen et al. SCIENCE
- Structural basis of dual Ca2+/pH regulation of the endolysosomal TRPML1 channel
- (2017) Minghui Li et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The First Extracellular Linker Is Important for Several Aspects of the Gating Mechanism of Human TRPA1 Channel
- (2017) Lenka Marsakova et al. Frontiers in Molecular Neuroscience
- Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2)
- (2016) Mariana Grieben et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Rational design and validation of a vanilloid-sensitive TRPV2 ion channel
- (2016) Fan Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of the full-length TRPV2 channel by cryo-EM
- (2016) Kevin W. Huynh et al. Nature Communications
- Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2)
- (2016) Mariana Grieben et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Quantifying side-chain conformational variations in protein structure
- (2016) Zhichao Miao et al. Scientific Reports
- Activation of Transient Receptor Potential Ankyrin-1 by Insoluble Particulate Material and Association with Asthma
- (2015) Cassandra E. Deering-Rice et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Understanding Thermosensitive Transient Receptor Potential Channels as Versatile Polymodal Cellular Sensors
- (2015) Jacob K. Hilton et al. BIOCHEMISTRY
- Adaptability of protein structures to enable functional interactions and evolutionary implications
- (2015) Turkan Haliloglu et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Dissecting π-helices: sequence, structure and function
- (2015) Prasun Kumar et al. FEBS Journal
- Structure of the TRPA1 ion channel suggests regulatory mechanisms
- (2015) Candice E. Paulsen et al. NATURE
- Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin
- (2015) Khaled Elokely et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Purification and Structural Study of the Voltage-Sensor Domain of the Human KCNQ1 Potassium Ion Channel
- (2014) Dungeng Peng et al. BIOCHEMISTRY
- Classification of Intrinsically Disordered Regions and Proteins
- (2014) Robin van der Lee et al. CHEMICAL REVIEWS
- Conservation analysis of residues in the S4–S5 linker and the terminal part of the S5-P-S6 pore modulus in Kv and HCN channels: flexible determinants for the electromechanical coupling
- (2014) Daniel Balleza et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- ComplexN-Glycosylation Stabilizes Surface Expression of Transient Receptor Potential Melastatin 4b Protein
- (2013) Seung Kyoon Woo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functionally Important Amino Acid Residues in the Transient Receptor Potential Vanilloid 1 (TRPV1) Ion Channel - An Overview of the Current Mutational Data
- (2013) Zoltán Winter et al. Molecular Pain
- Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations
- (2012) Yuanyuan Cui et al. JOURNAL OF GENERAL PHYSIOLOGY
- Tracking a complete voltage-sensor cycle with metal-ion bridges
- (2012) U. Henrion et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Being Flexible: The Voltage-Controllable Activation Gate of Kv Channels
- (2012) Alain J. Labro et al. Frontiers in Pharmacology
- 310-Helix Conformation Facilitates the Transition of a Voltage Sensor S4 Segment toward the Down State
- (2011) Christine S. Schwaiger et al. BIOPHYSICAL JOURNAL
- Biogenesis of the pore architecture of a voltage-gated potassium channel
- (2011) C. Gajewski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 310helices in channels and other membrane proteins
- (2010) Ricardo Simão Vieira-Pires et al. JOURNAL OF GENERAL PHYSIOLOGY
- The elusive π-helix
- (2010) R. Peter Riek et al. JOURNAL OF STRUCTURAL BIOLOGY
- Thermosensitive TRP channel pore turret is part of the temperature activation pathway
- (2010) F. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Effect of Loops on the Structural Organization of α-Helical Membrane Proteins
- (2009) Oznur Tastan et al. BIOPHYSICAL JOURNAL
- Conformational dynamics of the inner pore helix of voltage-gated potassium channels
- (2009) Seungho Choe et al. JOURNAL OF CHEMICAL PHYSICS
- Sequential formation of ion pairs during activation of a sodium channel voltage sensor
- (2009) Paul G. DeCaen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional Analysis of Kv1.2 and Paddle Chimera Kv Channels in Planar Lipid Bilayers
- (2008) Xiao Tao et al. JOURNAL OF MOLECULAR BIOLOGY
- Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel
- (2008) G. M. Clayton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- S4-based voltage sensors have three major conformations
- (2008) C. A. Villalba-Galea et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now