Conformational plasticity in the selectivity filter of the TRPV2 ion channel

Opening of the human epithelial calcium channel TRPV6

(2017) Luke L. McGoldrick et al.   NATURE

Structures of closed and open states of a voltage-gated sodium channel

(2017) Michael J. Lenaeus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use Dependence of Heat Sensitivity of Vanilloid Receptor TRPV2

(2016) Beiying Liu et al.   BIOPHYSICAL JOURNAL

Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating

(2016) Doreen Matthies et al.   CELL

TRPing on the pore phenomenon: what do we know about transient receptor potential ion channel-related pore dilation up to now?

(2016) L. G. B. Ferreira et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

(2016) Yuan Gao et al.   NATURE

Crystal structure of the epithelial calcium channel TRPV6

(2016) Kei Saotome et al.   NATURE

Cryo-electron microscopy structure of the TRPV2 ion channel

(2016) Lejla Zubcevic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rational design and validation of a vanilloid-sensitive TRPV2 ion channel

(2016) Fan Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the full-length TRPV2 channel by cryo-EM

(2016) Kevin W. Huynh et al.   Nature Communications

Cryo-electron microscopy structure of the TRPV2 ion channel

(2016) Lejla Zubcevic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Temperature-sensitive gating of TRPV1 channel as probed by atomistic simulations of its trans- and juxtamembrane domains

(2016) Anton O. Chugunov et al.   Scientific Reports

Role of the Outer Pore Domain in Transient Receptor Potential Vanilloid 1 Dynamic Permeability to Large Cations

(2015) Clare H. Munns et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pore dilation reconsidered

(2015) Bruce P Bean   NATURE NEUROSCIENCE

Physical basis of apparent pore dilation of ATP-activated P2X receptor channels

(2015) Mufeng Li et al.   NATURE NEUROSCIENCE

Measurement of relative Ca2+ permeability during sustained activation of TRPV1 receptors

(2015) Damien S. K. Samways et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography

(2013) James Foadi et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block

(2013) C Brenneis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314

(2013) Michelino Puopolo et al.   JOURNAL OF NEUROPHYSIOLOGY

TRPV1 structures in distinct conformations reveal activation mechanisms

(2013) Erhu Cao et al.   NATURE

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

(2013) Maofu Liao et al.   NATURE

Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents

(2012) Massimo Nabissi et al.   CARCINOGENESIS

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Activity-dependent targeting of TRPV1 with a pore-permeating capsaicin analog

(2011) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation

(2010) T. G. Banke et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Coapplication of Lidocaine and the Permanently Charged Sodium Channel Blocker QX-314 Produces a Long-lasting Nociceptive Blockade in Rodents

(2009) Alexander M. Binshtok et al.   ANESTHESIOLOGY

TRPV1 shows dynamic ionic selectivity during agonist stimulation

(2008) Man-Kyo Chung et al.   NATURE NEUROSCIENCE