GSK-3β: An exuberating neuroinflammatory mediator in Parkinson's disease
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Title
GSK-3β: An exuberating neuroinflammatory mediator in Parkinson's disease
Authors
Keywords
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Journal
BIOCHEMICAL PHARMACOLOGY
Volume 210, Issue -, Pages 115496
Publisher
Elsevier BV
Online
2023-03-11
DOI
10.1016/j.bcp.2023.115496
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Note: Only part of the references are listed.- Inter and intracellular mitochondrial transfer: Future of mitochondrial transplant therapy in Parkinson’s disease
- (2023) Rachit Jain et al. BIOMEDICINE & PHARMACOTHERAPY
- Piceatannol promotes neuroprotection by inducing mitophagy and mitobiogenesis in the experimental diabetic peripheral neuropathy and hyperglycemia-induced neurotoxicity
- (2023) Islauddin Khan et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- GSK3β mediates the spatiotemporal dynamics of NLRP3 inflammasome activation
- (2022) Suyavaran Arumugam et al. CELL DEATH AND DIFFERENTIATION
- GSK-3β-mediated activation of NLRP3 inflammasome leads to pyroptosis and apoptosis of rat cardiomyocytes and fibroblasts
- (2022) Shu-Hui Wang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Coenzyme Q10 attenuates renal fibrosis by inhibiting RIP1-RIP3-MLKL-mediated necroinflammation via Wnt3α/β-catenin/GSK-3β signaling in unilateral ureteral obstruction
- (2022) Yu Ji Jiang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Sevoflurane suppresses NLRP3 inflammasome-mediated pyroptotic cell death to attenuate lipopolysaccharide-induced acute lung injury through inducing GSK-3β phosphorylation and activation
- (2022) Fushuang Zheng et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Understanding the Involvement of microRNAs in Mitochondrial Dysfunction and Their Role as Potential Biomarkers and Therapeutic Targets in Parkinson’s Disease
- (2022) Kamatham Pushpa Tryphena et al. JOURNAL OF ALZHEIMERS DISEASE
- A GLP1 receptor agonist diabetes drug ameliorates neurodegeneration in a mouse model of infantile neurometabolic disease
- (2022) L. Poupon-Bejuit et al. Scientific Reports
- NLRP3 inflammasomes: A potential target to improve mitochondrial biogenesis in Parkinson's disease
- (2022) Mayuri Khot et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Pathological and Therapeutic Advances in Parkinson’s Disease: Mitochondria in the Interplay
- (2022) Padmashri Naren et al. JOURNAL OF ALZHEIMERS DISEASE
- Snail-regulated exosomal microRNA-21 suppresses NLRP3 inflammasome activity to enhance cisplatin resistance
- (2022) Han-Ying Cheng et al. Journal for ImmunoTherapy of Cancer
- Itaconate Attenuates Neuroinflammation and Exerts Dopamine Neuroprotection in Parkinson’s Disease through Inhibiting NLRP3 Inflammasome
- (2022) Guoqing Sun et al. Brain Sciences
- Proteostasis in Parkinson's disease: Recent development and possible implication in diagnosis and therapeutics
- (2022) Amrita Kulkarni et al. AGEING RESEARCH REVIEWS
- Neuroprotective Effect of Phloretin in Rotenone-Induced Mice Model of Parkinson’s Disease: Modulating mTOR-NRF2-p62 Mediated Autophagy-Oxidative Stress Crosstalk
- (2022) Shubhendu M. Shirgadwar et al. JOURNAL OF ALZHEIMERS DISEASE
- IGF-1 Alleviates Mitochondrial Apoptosis through the GSK3β/NF-κB/NLRP3 Signaling Pathway in LPS-Treated PC-12 Cells
- (2021) Feng Wang et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Inhibition of miR-129 Improves Neuronal Pyroptosis and Cognitive Impairment Through IGF-1/GSK3β Signaling Pathway: An In Vitro and In Vivo Study
- (2021) Feng Wang et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Parkinson’s Disease: Potential Actions of Lithium by Targeting the WNT/β-Catenin Pathway, Oxidative Stress, Inflammation and Glutamatergic Pathway
- (2021) Alexandre Vallée et al. Cells
- Carvacrol abates NLRP3 inflammasome activation by augmenting Keap1/Nrf-2/p62 directed autophagy and mitochondrial quality control in neuropathic pain
- (2021) Vijay Kumar Arruri et al. NUTRITIONAL NEUROSCIENCE
- Role of MicroRNAs, Aptamers in Neuroinflammation and Neurodegenerative Disorders
- (2021) Islauddin Khan et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Glycogen synthase kinase-3β (GSK-3β) deficiency inactivates the NLRP3 inflammasome-mediated cell pyroptosis in LPS-treated periodontal ligament cells (PDLCs)
- (2021) Xiaolu Zhang et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- Cdk5 and GSK3β inhibit fast endophilin-mediated endocytosis
- (2021) Antonio P. A. Ferreira et al. Nature Communications
- Glycogen Synthase Kinase 3β Modulates the Inflammatory Response Activated by Bacteria, Viruses, and Parasites
- (2021) Ricarda Cortés-Vieyra et al. Frontiers in Immunology
- Highly accurate protein structure prediction with AlphaFold
- (2021) John Jumper et al. NATURE
- Attenuated Postprandial GLP-1 Response in Parkinson’s Disease
- (2021) Richard A. Manfready et al. Frontiers in Neuroscience
- The Nrf2-NLRP3-caspase-1 axis mediates the neuroprotective effects of Celastrol in Parkinson's disease
- (2021) Chenyu Zhang et al. Redox Biology
- Parkinson disease-associated cognitive impairment
- (2021) Dag Aarsland et al. Nature Reviews Disease Primers
- Ephedrine ameliorates cerebral ischemia injury via inhibiting NOD-like receptor pyrin domain 3 inflammasome activation through the Akt/GSK3β/NRF2 pathway
- (2021) Qunxian Li et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Glia: A major player in glutamate–GABA dysregulation‐mediated neurodegeneration
- (2021) Anika Sood et al. JOURNAL OF NEUROSCIENCE RESEARCH
- α-Synuclein Induces the GSK-3-Mediated Phosphorylation and Degradation of NURR1 and Loss of Dopaminergic Hallmarks
- (2021) Ángel Juan García-Yagüe et al. MOLECULAR NEUROBIOLOGY
- A Novel Long-Noncoding RNA LncZFAS1 Prevents MPP+-Induced Neuroinflammation Through MIB1 Activation
- (2021) Ziman Zhu et al. MOLECULAR NEUROBIOLOGY
- Inhibition of NLRP3 inflammasome by glibenclamide attenuated dopaminergic neurodegeneration and motor deficits in paraquat and maneb-induced mouse Parkinson’s disease model
- (2021) Xiaofei Qiu et al. TOXICOLOGY LETTERS
- Alpha-Synuclein Induced Immune Cells Activation and Associated Therapy in Parkinson’s Disease
- (2021) Ruichen Su et al. Frontiers in Aging Neuroscience
- α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease
- (2020) Cecilia S. Lindestam Arlehamn et al. Nature Communications
- Roles of GSK-3 and β-Catenin in Antiviral Innate Immune Sensing of Nucleic Acids
- (2020) Alexandre Marineau et al. Cells
- GSK3: A Kinase Balancing Promotion and Resolution of Inflammation
- (2020) Leonie Hoffmeister et al. Cells
- Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson’s Disease
- (2020) Rita Maria Concetta Di Martino et al. ACS Chemical Neuroscience
- Adiponectin peptide alleviates oxidative stress and NLRP3 inflammasome activation after cerebral ischemia-reperfusion injury by regulating AMPK/GSK-3β
- (2020) Haixiao Liu et al. EXPERIMENTAL NEUROLOGY
- GSK-3β Contributes to Parkinsonian Dopaminergic Neuron Death: Evidence From Conditional Knockout Mice and Tideglusib
- (2020) Junyu Li et al. Frontiers in Molecular Neuroscience
- Glycogen synthase kinase 3 (GSK-3) inhibitors: a patent update (2016–2019)
- (2020) Carlos Roca et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- The NLRP3 inflammasome: Mechanism of action, role in disease and therapies
- (2020) Li Wang et al. MOLECULAR ASPECTS OF MEDICINE
- Celecoxib promotes survival and upregulates the expression of neuroprotective marker genes in two different in vitro models of Parkinson's disease
- (2020) Sarah Dassati et al. NEUROPHARMACOLOGY
- Inhibition of GSK-3β alleviates cerebral ischemia/reperfusion injury in rats by suppressing NLRP3 inflammasome activation through autophagy
- (2019) Yueting Wang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Inflammasomes in neuroinflammatory and neurodegenerative diseases
- (2019) Sofie Voet et al. EMBO Molecular Medicine
- The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
- (2019) Nathan Kelley et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- 2,5-Dimethylcelecoxib prevents isoprenaline-induced cardiomyocyte hypertrophy and cardiac fibroblast activation by inhibiting Akt-mediated GSK-3 phosphorylation
- (2019) Shoji Morishige et al. BIOCHEMICAL PHARMACOLOGY
- β-Catenin Is Required for the cGAS/STING Signaling Pathway but Antagonized by the Herpes Simplex Virus 1 US3 Protein
- (2019) Hongjuan You et al. JOURNAL OF VIROLOGY
- A partnership with the proteasome; the destructive nature of GSK3
- (2018) Holly Robertson et al. BIOCHEMICAL PHARMACOLOGY
- Aberrant regulation of the GSK‐3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy
- (2018) Pablo Ranea‐Robles et al. EMBO Molecular Medicine
- Cathepsin B links oxidative stress to the activation of NLRP3 inflammasome
- (2018) Hua Bai et al. EXPERIMENTAL CELL RESEARCH
- Crosstalk Between Peroxisome Proliferator-Activated Receptor Gamma and the Canonical WNT/β-Catenin Pathway in Chronic Inflammation and Oxidative Stress During Carcinogenesis
- (2018) Alexandre Vallée et al. Frontiers in Immunology
- Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy
- (2018) Antonio Cuadrado et al. Redox Biology
- Neuroprotective effects of MHY908, a PPAR α/γ dual agonist, in a MPTP-induced Parkinson’s disease model
- (2018) Yujeong Lee et al. BRAIN RESEARCH
- PPAR-γ agonist pioglitazone reduces microglial proliferation and NF-κB activation in the substantia nigra in the 6-hydroxydopamine model of Parkinson’s disease
- (2018) Meira Maria Forcelini Machado et al. Pharmacological Reports
- Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
- (2018) Richard Gordon et al. Science Translational Medicine
- Epidemiology of Parkinson’s disease
- (2017) Ole-Bjørn Tysnes et al. JOURNAL OF NEURAL TRANSMISSION
- NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation
- (2017) Nan Song et al. MOLECULAR CELL
- T cells from patients with Parkinson’s disease recognize α-synuclein peptides
- (2017) David Sulzer et al. NATURE
- Stressed and Inflamed, Can GSK3 Be Blamed?
- (2017) Richard S. Jope et al. TRENDS IN BIOCHEMICAL SCIENCES
- Dopamine and Acetylcholine, a Circuit Point of View in Parkinson’s Disease
- (2017) Giorgio Rizzi et al. Frontiers in Neural Circuits
- MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism
- (2017) Xuan Li et al. Nature Communications
- Stress-induced neuroinflammation is mediated by GSK3-dependent TLR4 signaling that promotes susceptibility to depression-like behavior
- (2016) Yuyan Cheng et al. BRAIN BEHAVIOR AND IMMUNITY
- NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
- (2016) Zhenyu Zhong et al. CELL
- Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway
- (2016) Jie Yu et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- A polarizing question: do M1 and M2 microglia exist?
- (2016) Richard M Ransohoff NATURE NEUROSCIENCE
- Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β
- (2015) Shengquan Hu et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- M1 and M2 immune activation in Parkinson’s Disease: Foe and ally?
- (2015) M.S. Moehle et al. NEUROSCIENCE
- The molecular mechanism of rotenone-induced α-synuclein aggregation: Emphasizing the role of the calcium/GSK3β pathway
- (2015) Yu-he Yuan et al. TOXICOLOGY LETTERS
- Neuroinflammation in Parkinson’s disease and its potential as therapeutic target
- (2015) Qinqin Wang et al. Translational Neurodegeneration
- Neuroinflammation and M2 microglia: the good, the bad, and the inflamed
- (2014) Jonathan D Cherry et al. Journal of Neuroinflammation
- Association of glycogen synthase kinase-3β with Parkinson’s disease (Review)
- (2014) DA-WEI LI et al. Molecular Medicine Reports
- Extracellular α-Synuclein Leads to Microtubule Destabilization via GSK-3β-Dependent Tau Phosphorylation in PC12 Cells
- (2014) Magdalena Gąssowska et al. PLoS One
- GSK-3α is a central regulator of age-related pathologies in mice
- (2013) Jibin Zhou et al. JOURNAL OF CLINICAL INVESTIGATION
- AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans
- (2013) Biljana Georgievska et al. JOURNAL OF NEUROCHEMISTRY
- Peroxisome proliferator activated receptor gamma (PPARγ) as a therapeutic target for improvement of cognitive performance in Fragile-X
- (2013) Mohammad Jodeiri Farshbaf et al. MEDICAL HYPOTHESES
- Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation
- (2013) Cintia Roodveldt et al. PLoS One
- TRPM2 links oxidative stress to NLRP3 inflammasome activation
- (2013) Zhenyu Zhong et al. Nature Communications
- Glycogen Synthase Kinase-3 Inhibitors as Potent Therapeutic Agents for the Treatment of Parkinson Disease.
- (2012) J. A. Morales-García et al. ACS Chemical Neuroscience
- Inactivation of the Enzyme GSK3α by the Kinase IKKi Promotes AKT-mTOR Signaling Pathway that Mediates Interleukin-1-Induced Th17 Cell Maintenance
- (2012) Muhammet F. Gulen et al. IMMUNITY
- Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β
- (2011) Fumitaka Kawakami et al. FEBS Journal
- Involvment of Cytosolic and Mitochondrial GSK-3β in Mitochondrial Dysfunction and Neuronal Cell Death of MPTP/MPP+-Treated Neurons
- (2009) Agnès Petit-Paitel et al. PLoS One
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GSK3: a multifaceted kinase in Wnt signaling
- (2009) Dianqing Wu et al. TRENDS IN BIOCHEMICAL SCIENCES
- Parkin Protects Dopaminergic Neurons against Microtubule-depolymerizing Toxins by Attenuating Microtubule-associated Protein Kinase Activation
- (2008) Yong Ren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Elevated glycogen synthase kinase-3 activity in Fragile X mice: Key metabolic regulator with evidence for treatment potential
- (2008) Wenzhong William Min et al. NEUROPHARMACOLOGY
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