GSK-3α is a central regulator of age-related pathologies in mice

mTOR's role in ageing: protein synthesis or autophagy?

(2016) Sarah L. Hands et al.   Aging-US

Sestrins at the crossroad between stress and aging

(2016) Jun Hee Lee et al.   Aging-US

GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy

(2012) S.-Y. Lin et al.   SCIENCE

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

(2011) Hong-Min Ni et al.   Autophagy

Regulation of protein stability by GSK3 mediated phosphorylation

(2011) Chong Xu et al.   CELL CYCLE

Glycogen Synthase Kinase-3α Limits Ischemic Injury, Cardiac Rupture, Post–Myocardial Infarction Remodeling and Death

(2011) Hind Lal et al.   CIRCULATION

Telomere dysfunction induces metabolic and mitochondrial compromise

(2011) Ergün Sahin et al.   NATURE

Tubular aggregates in skeletal muscle: Just a special type of protein aggregates?

(2011) Stefano Schiaffino   NEUROMUSCULAR DISORDERS

GSK-3: Functional Insights from Cell Biology and Animal Models

(2011) Oksana Kaidanovich-Beilin et al.   Frontiers in Molecular Neuroscience

Oxidative Stress Stimulates Autophagic Flux During Ischemia/Reperfusion

(2010) Nirmala Hariharan et al.   ANTIOXIDANTS & REDOX SIGNALING

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Stressin' Sestrins take an aging fight

(2010) Andrei V. Budanov et al.   EMBO Molecular Medicine

Wnt signaling regulates mitochondrial physiology and insulin sensitivity

(2010) J. C. Yoon et al.   GENES & DEVELOPMENT

Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling Symphony

(2010) Kathryn G. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GSK-3α directly regulates β-adrenergic signaling and the response of the heart to hemodynamic stress in mice

(2010) Jibin Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Glycogen synthase kinase 3β mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1

(2010) Sanhua Leng et al.   JOURNAL OF ENDOCRINOLOGY

Targeting GSK-3 family members in the heart: A very sharp double-edged sword

(2010) Hui Cheng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Autophagy: assays and artifacts

(2010) Sandra Barth et al.   JOURNAL OF PATHOLOGY

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Can autophagy promote longevity?

(2010) Frank Madeo et al.   NATURE CELL BIOLOGY

DNA damage response and cellular senescence in tissues of aging mice

(2009) Chunfang Wang et al.   AGING CELL

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

AMP-Activated Protein Kinase Deficiency Enhances Myocardial Ischemia/Reperfusion Injury but Has Minimal Effect on the Antioxidant/Antinitrative Protection of Adiponectin

(2009) Yajing Wang et al.   CIRCULATION

Role of telomere dysfunction in aging and its detection by biomarkers

(2009) Guido von Figura et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

The regulation of aging: does autophagy underlie longevity?

(2009) Tibor Vellai et al.   TRENDS IN CELL BIOLOGY

Genes encoding longevity: from model organisms to humans

(2008) Maris Kuningas et al.   AGING CELL

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

(2008) Andrei V. Budanov et al.   CELL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Wnt and beyond Wnt: Multiple mechanisms control the transcriptional property of β-catenin

(2008) Tianru Jin et al.   CELLULAR SIGNALLING

Unique and Overlapping Functions of GSK-3 Isoforms in Cell Differentiation and Proliferation and Cardiovascular Development

(2008) Thomas Force et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of GSK-3β in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation

(2008) Risto Kerkela et al.   JOURNAL OF CLINICAL INVESTIGATION

Micro-CT analysis with multiple thresholds allows detection of bone formation and resorption during ultrasound-treated fracture healing

(2008) Theresa A. Freeman et al.   JOURNAL OF ORTHOPAEDIC RESEARCH