MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism
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Title
MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism
Authors
Keywords
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Journal
Nature Communications
Volume 8, Issue -, Pages 15986
Publisher
Springer Nature
Online
2017-06-28
DOI
10.1038/ncomms15986
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- (2016) Yuan He et al. NATURE
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- Proteasome Failure Promotes Positioning of Lysosomes around the Aggresome via Local Block of Microtubule-Dependent Transport
- (2014) N. Zaarur et al. MOLECULAR AND CELLULAR BIOLOGY
- The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK family: a computational approach to obstruct the role of MARK4 in prostate cancer progression
- (2014) Pranitha Jenardhanan et al. Molecular BioSystems
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- (2014) William O. Hancock NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity
- (2013) S. Park et al. JOURNAL OF IMMUNOLOGY
- Inflammation: A complex problem
- (2013) Katharine Gammon NATURE
- Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
- (2013) Takuma Misawa et al. NATURE IMMUNOLOGY
- Role of Individual MARK Isoforms in Phosphorylation of Tau at Ser262 in Alzheimer’s Disease
- (2013) Gucci Jijuan Gu et al. NEUROMOLECULAR MEDICINE
- An NLRP7-Containing Inflammasome Mediates Recognition of Microbial Lipopeptides in Human Macrophages
- (2012) Sonal Khare et al. IMMUNITY
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- (2012) Chao Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Microtubule-associated Protein/Microtubule Affinity-regulating Kinase 4 (MARK4) Is a Negative Regulator of the Mammalian Target of Rapamycin Complex 1 (mTORC1)
- (2012) Li Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inflammasomes in health and disease
- (2012) Till Strowig et al. NATURE
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- (2012) Michael T. Heneka et al. NATURE
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- (2012) A. R. Shenoy et al. SCIENCE
- Crystallization and preliminary X-ray crystallographic studies of the PYD domain of human NALP3
- (2011) Ju Young Bae et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- A critical role for the PAR-1/MARK-tau axis in mediating the toxic effects of Aβ on synapses and dendritic spines
- (2011) Wendou Yu et al. HUMAN MOLECULAR GENETICS
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- (2011) Richard M. Parton et al. JOURNAL OF CELL BIOLOGY
- Microtubules induce self-organization of polarized PAR domains in Caenorhabditis elegans zygotes
- (2011) Fumio Motegi et al. NATURE CELL BIOLOGY
- The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
- (2011) Bolormaa Vandanmagsar et al. NATURE MEDICINE
- Proximity ligation assays: a recent addition to the proteomics toolbox
- (2010) Irene Weibrecht et al. Expert Review of Proteomics
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- Direct conversion of fibroblasts to functional neurons by defined factors
- (2010) Thomas Vierbuchen et al. NATURE
- Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation
- (2010) Kristiina Rajamäki et al. PLoS One
- Proteomic Analysis of Microtubule-associated Proteins during Macrophage Activation
- (2009) Prerna C. Patel et al. MOLECULAR & CELLULAR PROTEOMICS
- T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes
- (2009) Greta Guarda et al. NATURE
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- (2009) Dragana Nes̆ić et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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