Proteostasis in Parkinson's disease: Recent development and possible implication in diagnosis and therapeutics
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Proteostasis in Parkinson's disease: Recent development and possible implication in diagnosis and therapeutics
Authors
Keywords
-
Journal
AGEING RESEARCH REVIEWS
Volume 84, Issue -, Pages 101816
Publisher
Elsevier BV
Online
2022-12-06
DOI
10.1016/j.arr.2022.101816
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Early downregulation of hsa-miR-144-3p in serum from drug-naïve Parkinson’s disease patients
- (2022) Elisa Zago et al. Scientific Reports
- LRRK2, GBA and their interaction in the regulation of autophagy: implications on therapeutics in Parkinson's disease
- (2022) Shirley Yin-Yu Pang et al. Translational Neurodegeneration
- Reducing neuroinflammation via therapeutic compounds and lifestyle to prevent or delay progression of Parkinson’s disease
- (2022) Elodie Kip et al. AGEING RESEARCH REVIEWS
- Detection of neuron-derived pathological α-synuclein in blood
- (2022) Annika Kluge et al. BRAIN
- CHIP protects against MPP+/MPTP-induced damage by regulating Drp1 in two models of Parkinson’s disease
- (2021) Zhengwei Hu et al. Aging-US
- Targeted attenuation of elevated histone marks at SNCA alleviates α‐synuclein in Parkinson's disease
- (2021) Subhrangshu Guhathakurta et al. EMBO Molecular Medicine
- Cross-talks among GBA mutations, glucocerebrosidase, and α-synuclein in GBA-associated Parkinson’s disease and their targeted therapeutic approaches: a comprehensive review
- (2021) Tapan Behl et al. Translational Neurodegeneration
- Dysfunction of RAB39B‐ Mediated Vesicular Trafficking in Lewy Body Diseases
- (2021) David J. Koss et al. MOVEMENT DISORDERS
- Atremorine in Parkinson's disease: From dopaminergic neuroprotection to pharmacogenomics
- (2021) Ramón Cacabelos et al. MEDICINAL RESEARCH REVIEWS
- Neuronal autophagy and mitophagy in Parkinson's disease
- (2021) Britney N. Lizama et al. MOLECULAR ASPECTS OF MEDICINE
- Deubiquitinating enzymes (DUBs): decipher underlying basis of neurodegenerative diseases
- (2021) Baohua Liu et al. MOLECULAR PSYCHIATRY
- Enrichment of rare variants in E3 ubiquitin ligase genes in Early onset Parkinson's disease
- (2021) Xiaojing Gu et al. NEUROBIOLOGY OF AGING
- ATP13A2 levels in serum and cerebrospinal fluid in patients with idiopathic Parkinson's disease
- (2021) Emilio Fernández-Espejo et al. PARKINSONISM & RELATED DISORDERS
- Protein clearance strategies for disease intervention
- (2021) Franziska Hommen et al. JOURNAL OF NEURAL TRANSMISSION
- Parkinson's disease risk genes act in glia to control neuronal α-synuclein toxicity
- (2021) Abby L. Olsen et al. NEUROBIOLOGY OF DISEASE
- Molecular chaperones and Parkinson's disease
- (2021) Shenglan Hu et al. NEUROBIOLOGY OF DISEASE
- Serum miR-214 Serves as a Biomarker for Prodromal Parkinson’s Disease
- (2021) Lanting Li et al. Frontiers in Aging Neuroscience
- Mapping the Diverse and Inclusive Future of Parkinson’s Disease Genetics and Its Widespread Impact
- (2021) Inas Elsayed et al. Genes
- Ambroxol for the Treatment of Patients With Parkinson Disease With and Without Glucocerebrosidase Gene Mutations
- (2020) Stephen Mullin et al. JAMA Neurology
- Nonmercaptalbumin as an oxidative stress marker in Parkinson’s and PARK2 disease
- (2020) Shin‐Ichi Ueno et al. Annals of Clinical and Translational Neurology
- Impairment of Lysosome Function and Autophagy in Rare Neurodegenerative Diseases
- (2020) Frédéric Darios et al. JOURNAL OF MOLECULAR BIOLOGY
- Mechanisms, regulation and functions of the unfolded protein response
- (2020) Claudio Hetz et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Histone Deacetylases Inhibitors in Neurodegenerative Diseases, Neuroprotection and Neuronal Differentiation
- (2020) Surabhi Shukla et al. Frontiers in Pharmacology
- Safety and immunogenicity of the α-synuclein active immunotherapeutic PD01A in patients with Parkinson's disease: a randomised, single-blinded, phase 1 trial
- (2020) Dieter Volc et al. LANCET NEUROLOGY
- Accurate MS-based Rab10 phosphorylation stoichiometry determination as readout for LRRK2 activity in Parkinson’s disease
- (2020) Ozge Karayel et al. MOLECULAR & CELLULAR PROTEOMICS
- Cathepsin K is a potent disaggregase of α-synuclein fibrils
- (2020) Ryan P. McGlinchey et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Emerging role of S100B protein implication in Parkinson’s disease pathogenesis
- (2020) Efthalia Angelopoulou et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Reduced serum SIRT1 levels in patients with Parkinson’s disease: a cross-sectional study in China
- (2020) Yuting Zhu et al. NEUROLOGICAL SCIENCES
- Pathophysiology of Parkinson's disease: Mitochondria, alpha-synuclein and much more…
- (2020) T. Rouaud et al. REVUE NEUROLOGIQUE
- Pro-cathepsin D, Prosaposin, and Progranulin: Lysosomal Networks in Parkinsonism
- (2020) Nahid Tayebi et al. TRENDS IN MOLECULAR MEDICINE
- Ubiquitin signaling in neurodegenerative diseases: an autophagy and proteasome perspective
- (2020) François Le Guerroué et al. CELL DEATH AND DIFFERENTIATION
- Involvement of aberrant regulation of epigenetic mechanisms in the pathogenesis of Parkinson's disease and epigenetic‐based therapies
- (2019) Pedram G. Renani et al. JOURNAL OF CELLULAR PHYSIOLOGY
- LRP10 in autosomal‐dominant Parkinson's disease
- (2019) You Chen et al. MOVEMENT DISORDERS
- A Cleaning Crew: The Pursuit of Autophagy in Parkinson’s Disease
- (2019) Pathik Parekh et al. ACS Chemical Neuroscience
- Pharmacogenetics of Atremorine-Induced Neuroprotection and Dopamine Response in Parkinsonʼs Disease
- (2019) Ramón Cacabelos et al. PLANTA MEDICA
- Novel POLG mutation in a patient with early-onset parkinsonism, progressive external ophthalmoplegia and optic atrophy
- (2019) Lin Ma et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Autophagy lysosomal pathway dysfunction in Parkinson's disease; evidence from human genetics
- (2019) Konstantin Senkevich et al. PARKINSONISM & RELATED DISORDERS
- Expression Profiling of Blood microRNAs 885, 361, and 17 in the Patients with the Parkinson’s disease: Integrating Interaction Data to Uncover the Possible Triggering Age-Related Mechanisms
- (2019) Molood Behbahanipour et al. Scientific Reports
- Autophagic- and Lysosomal-Related Biomarkers for Parkinson’s Disease: Lights and Shadows
- (2019) Helena Xicoy et al. Cells
- miR-124 and Parkinson’s disease: A biomarker with therapeutic potential
- (2019) Efthalia Angelopoulou et al. PHARMACOLOGICAL RESEARCH
- Guanabenz promotes neuronal survival via enhancement of ATF4 and parkin expression in models of Parkinson disease
- (2018) Xiaotian Sun et al. EXPERIMENTAL NEUROLOGY
- The c-Abl inhibitor, Radotinib HCl, is neuroprotective in a preclinical Parkinson’s disease mouse model
- (2018) Saebom Lee et al. HUMAN MOLECULAR GENETICS
- Mitochondrial Proteostasis in the Context of Cellular and Organismal Health and Aging
- (2018) Erica A Moehle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease
- (2018) Gabriela Mercado et al. NEUROBIOLOGY OF DISEASE
- DNAJC13 mutation screening in patients with Parkinson's disease from South Italy
- (2018) Monica Gagliardi et al. PARKINSONISM & RELATED DISORDERS
- Identification of aberrant circulating miRNAs in Parkinson's disease plasma samples
- (2018) Lei Chen et al. Brain and Behavior
- Cellular Proteostasis in Neurodegeneration
- (2018) Alberim Kurtishi et al. MOLECULAR NEUROBIOLOGY
- ER stress and the unfolded protein response in neurodegeneration
- (2017) Claudio Hetz et al. Nature Reviews Neurology
- PLA2G6 accumulates in Lewy bodies in PARK14 and idiopathic Parkinson's disease
- (2017) Yasuo Miki et al. NEUROSCIENCE LETTERS
- Reduced Circulating Levels of miR-433 and miR-133b Are Potential Biomarkers for Parkinson’s Disease
- (2017) Xiong Zhang et al. Frontiers in Cellular Neuroscience
- Implications of DNA Methylation in Parkinson’s Disease
- (2017) Ernesto Miranda-Morales et al. Frontiers in Molecular Neuroscience
- LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation in a Parkinson’s Disease Mouse Model
- (2017) Hien Tran Zhao et al. Molecular Therapy-Nucleic Acids
- The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation
- (2017) Francesco A. Aprile et al. Scientific Reports
- Epigenetic regulation in Parkinson’s disease
- (2016) Catherine Labbé et al. ACTA NEUROPATHOLOGICA
- ER stress and Parkinson's disease: Pathological inputs that converge into the secretory pathway
- (2016) Gabriela Mercado et al. BRAIN RESEARCH
- Epigenetic inheritance of proteostasis and ageing
- (2016) C. Li et al. Essays in Biochemistry
- Oxidative Modification and Its Implications for the Neurodegeneration of Parkinson’s Disease
- (2016) Junjun Zhao et al. MOLECULAR NEUROBIOLOGY
- Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease
- (2016) Zoi Alexopoulou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Increased Rab35 expression is a potential biomarker and implicated in the pathogenesis of Parkinson’s disease
- (2016) Ching-Chi Chiu et al. Oncotarget
- Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson’s disease patients
- (2016) Yoshiro Saito et al. Scientific Reports
- Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases
- (2016) Qiuyang Zheng et al. Frontiers in Aging Neuroscience
- A panel of four decreased serum microRNAs as a novel biomarker for early Parkinson’s disease
- (2015) Hui Dong et al. BIOMARKERS
- Experimental Evidence Shows Salubrinal, an eIF2α Dephosphorylation Inhibitor, Reduces Xenotoxicant-Induced Cellular Damage
- (2015) Masato Matsuoka et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Regulation of Histone Acetylation by Autophagy in Parkinson Disease
- (2015) Goonho Park et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chaperones in Neurodegeneration
- (2015) I. Lindberg et al. JOURNAL OF NEUROSCIENCE
- α-Synuclein-mediated inhibition of ATF6 processing into COPII vesicles disrupts UPR signaling in Parkinson's disease
- (2015) Joel J. Credle et al. NEUROBIOLOGY OF DISEASE
- STEP61is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s disease
- (2015) Pradeep K. Kurup et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alpha-synuclein Toxicity in the Early Secretory Pathway: How It Drives Neurodegeneration in Parkinsons Disease
- (2015) Ting Wang et al. Frontiers in Neuroscience
- PGC−1α Promoter Methylation in Parkinson’s Disease
- (2015) Xiaomin Su et al. PLoS One
- Salubrinal protects against rotenone-induced SH-SY5Y cell death via ATF4-parkin pathway
- (2014) Liang Wu et al. BRAIN RESEARCH
- GSK-3β dysregulation contributes to parkinson’s-like pathophysiology with associated region-specific phosphorylation and accumulation of tau and α-synuclein
- (2014) J J Credle et al. CELL DEATH AND DIFFERENTIATION
- Identification of blood serum micro-RNAs associated with idiopathic andLRRK2Parkinson's disease
- (2014) Teresa Botta-Orfila et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Saposin C Protects Glucocerebrosidase against α-Synuclein Inhibition
- (2013) Thai Leong Yap et al. BIOCHEMISTRY
- Proteostasis and neurodegeneration: The roles of proteasomal degradation and autophagy
- (2013) Keiji Tanaka et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- DNAJC13 mutations in Parkinson disease
- (2013) Carles Vilariño-Güell et al. HUMAN MOLECULAR GENETICS
- Elevated TRAF2/6 expression in Parkinson’s disease is caused by the loss of Parkin E3 ligase activity
- (2013) Ji-Yun Chung et al. LABORATORY INVESTIGATION
- The role ofSCARB2as susceptibility factor in Parkinson's disease
- (2013) Franziska Hopfner et al. MOVEMENT DISORDERS
- Histone acetylation: molecular mnemonics on the chromatin
- (2013) Johannes Gräff et al. NATURE REVIEWS NEUROSCIENCE
- Epigenetic Landscape of Parkinson’s Disease: Emerging Role in Disease Mechanisms and Therapeutic Modalities
- (2013) Navneet Ammal Kaidery et al. Neurotherapeutics
- Epigenetic targeting of histone deacetylase: Therapeutic potential in Parkinson's disease?
- (2013) Ian F. Harrison et al. PHARMACOLOGY & THERAPEUTICS
- Influence of microRNA deregulation on chaperone-mediated autophagy and α-synuclein pathology in Parkinson's disease
- (2013) L Alvarez-Erviti et al. Cell Death & Disease
- HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers
- (2012) Marc L. Mendillo et al. CELL
- The unfolded protein response: controlling cell fate decisions under ER stress and beyond
- (2012) Claudio Hetz NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DJ-1 isoforms in whole blood as potential biomarkers of Parkinson disease
- (2012) Xiangmin Lin et al. Scientific Reports
- Phenylbutyrate Up-regulates the DJ-1 Protein and Protects Neurons in Cell Culture and in Animal Models of Parkinson Disease
- (2011) Wenbo Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- New developments in CSF biomarkers for early detection and monitoring of Parkinson disease
- (2011) Darran Yates Nature Reviews Neurology
- Molecular Chaperones and Associated Cellular Clearance Mechanisms against Toxic Protein Conformers in Parkinson’s Disease
- (2011) Marie-Pierre Hinault et al. Neurodegenerative Diseases
- Autosomal dominant Parkinson's disease
- (2011) Christina Sundal et al. PARKINSONISM & RELATED DISORDERS
- Autosomal recessive parkinsonism
- (2011) Vincenzo Bonifati PARKINSONISM & RELATED DISORDERS
- Chaperone-Mediated Autophagy Markers in Parkinson Disease Brains
- (2010) Lydia Alvarez-Erviti et al. ARCHIVES OF NEUROLOGY
- TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains
- (2010) Silvia Zucchelli et al. HUMAN MOLECULAR GENETICS
- Epigenetic modifications and human disease
- (2010) Anna Portela et al. NATURE BIOTECHNOLOGY
- TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodies
- (2010) Kunikazu Tanji et al. NEUROBIOLOGY OF DISEASE
- Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
- (2009) Hui Xiong et al. JOURNAL OF CLINICAL INVESTIGATION
- Relationship between alpha synuclein phosphorylation, proteasomal inhibition and cell death: relevance to Parkinson’s disease pathogenesis
- (2009) Kai-Yin Chau et al. JOURNAL OF NEUROCHEMISTRY
- Reciprocal Effects of α-Synuclein Overexpression and Proteasome Inhibition in Neuronal Cells and Tissue
- (2009) Melanie Dyllick-Brenzinger et al. NEUROTOXICITY RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started