Celecoxib promotes survival and upregulates the expression of neuroprotective marker genes in two different in vitro models of Parkinson's disease

Pomegranate activates TFEB to promote autophagy-lysosomal fitness and mitophagy

(2019) Sijie Tan et al.   Scientific Reports

Neuropsychiatric aspects of Parkinson’s disease

(2019) Anna Nagy et al.   JOURNAL OF NEURAL TRANSMISSION

Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases

(2019) King Faisal Yambire et al.   eLife

Neurotoxicity to dopamine neurons after the serial exposure to alcohol and methamphetamine: Protection by COX-2 antagonism

(2019) Amanda L. Blaker et al.   BRAIN BEHAVIOR AND IMMUNITY

Cross-organelle communication at the core of longevity

(2018) Nuno Raimundo et al.   Aging-US

Mitochondrial adventures at the organelle society

(2018) Cátia V. Diogo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Is Parkinson’s disease a lysosomal disorder?

(2018) Andrés D Klein et al.   BRAIN

Apolipoprotein D Concentration in Human Plasma during Aging and in Parkinson’s Disease: A Cross-Sectional Study

(2018) Andreas Waldner et al.   Parkinsons Disease

Synaptic, Mitochondrial, and Lysosomal Dysfunction in Parkinson’s Disease

(2018) Maria Nguyen et al.   TRENDS IN NEUROSCIENCES

Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease

(2017) Lena F. Burbulla et al.   SCIENCE

Mitochondrial Dysfunction and Neurodegeneration in Lysosomal Storage Disorders

(2017) Nicoletta Plotegher et al.   TRENDS IN MOLECULAR MEDICINE

Olfactory Dysfunction as an Early Biomarker in Parkinson’s Disease

(2017) Michelle E. Fullard et al.   Neuroscience Bulletin

Acute and chronic mitochondrial respiratory chain deficiency differentially regulate lysosomal biogenesis

(2017) Lorena Fernández-Mosquera et al.   Scientific Reports

Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidative stress

(2017) Raquel Pascua-Maestro et al.   PLoS Genetics

Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype

(2017) Xu Kang et al.   Scientific Reports

Nonmotor symptoms in patients with Parkinson disease

(2016) Tie-mei Zhang et al.   MEDICINE

Crosstalk between cellular compartments protects against proteotoxicity and extends lifespan

(2016) Matea Perić et al.   Scientific Reports

Bridging the age spectrum of neurodegenerative storage diseases

(2015) Barry Boland et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Mitochondria, autophagy and age-associated neurodegenerative diseases: New insights into a complex interplay

(2015) Eirini Lionaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Positron emission tomography in spinal infections

(2015) Alexandros Georgakopoulos et al.   CLINICAL IMAGING

Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease

(2015) Dominik Haddad et al.   FEBS LETTERS

Proteolytic degradation of neuropeptide Y (NPY) from head to toe: Identification of novel NPY-cleaving peptidases and potential drug interactions in CNS and Periphery

(2015) Leona Wagner et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy

(2015) Davor Ivankovic et al.   JOURNAL OF NEUROCHEMISTRY

Progress in unraveling the genetic etiology of Parkinson disease in a genomic era

(2015) Aline Verstraeten et al.   TRENDS IN GENETICS

Haploinsufficiency of cathepsin D leads to lysosomal dysfunction and promotes cell-to-cell transmission of α-synuclein aggregates

(2015) E-J Bae et al.   Cell Death & Disease

Apolipoprotein D takes center stage in the stress response of the aging and degenerative brain

(2014) Sarah Dassati et al.   NEUROBIOLOGY OF AGING

Pesticides exposure as etiological factors of Parkinson's disease and other neurodegenerative diseases—A mechanistic approach

(2014) Maria Teresa Baltazar et al.   TOXICOLOGY LETTERS

TFEB

(2013) Mickael Decressac et al.   Autophagy

Compartmentalized oxidative stress in dopaminergic cell death induced by pesticides and complex I inhibitors: Distinct roles of superoxide anion and superoxide dismutases

(2013) Humberto Rodriguez-Rocha et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neural and Immune Mechanisms in the Pathogenesis of Parkinson’s Disease

(2013) Fabio Blandini   Journal of Neuroimmune Pharmacology

COX-2 in the neurodegenerative process of Parkinson's disease

(2012) Peter Teismann   BIOFACTORS

Animal models of Parkinson’s disease

(2012) Fabio Blandini et al.   FEBS Journal

Calcium, Bioenergetics, and Neuronal Vulnerability in Parkinson's Disease

(2012) D. James Surmeier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system

(2012) N. S. Kirkby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prostanoid Receptors

(2011) Takako Hirata et al.   CHEMICAL REVIEWS

Transcriptional Activation of Lysosomal Exocytosis Promotes Cellular Clearance

(2011) Diego L. Medina et al.   DEVELOPMENTAL CELL

Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates

(2011) Timothy J. Collier et al.   NATURE REVIEWS NEUROSCIENCE

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats

(2010) Harikesh Kalonia et al.   NEUROTOXICOLOGY

Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions

(2009) Yaping Chu et al.   NEUROBIOLOGY OF DISEASE

Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons

(2009) Eugene V. Mosharov et al.   NEURON

Protective effect of cyclooxygenase (COX)-inhibitors against drug-induced catatonia and MPTP-induced striatal lesions in rats

(2009) Amit Gupta et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

Cathepsin D Is the Main Lysosomal Enzyme Involved in the Degradation of α-Synuclein and Generation of Its Carboxy-Terminally Truncated Species†

(2008) Daniel Sevlever et al.   BIOCHEMISTRY

Cathepsin D—Many functions of one aspartic protease

(2008) Petr Benes et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Altered vesicular dopamine storage in Parkinson's disease: a premature demise

(2008) W. Michael Caudle et al.   TRENDS IN NEUROSCIENCES