Inter and intracellular mitochondrial transfer: Future of mitochondrial transplant therapy in Parkinson’s disease

Direct Cell-Cell Communication via Membrane Pores, Gap Junction Channels, and Tunneling Nanotubes: Medical Relevance of Mitochondrial Exchange

(2022) Eliseo Eugenin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases

(2022) Zonghan Liu et al.   Cell and Bioscience

Prospects of mitochondrial transplantation in clinical medicine: Aspirations and challenges

(2022) Sina Hosseinian et al.   MITOCHONDRION

Mitochondrial electron transport chain defects modify Parkinson's disease phenotypes in a Drosophila model

(2022) Maria E. O'Hanlon et al.   NEUROBIOLOGY OF DISEASE

Stable transplantation of human mitochondrial DNA by high-throughput, pressurized isolated mitochondrial delivery

(2021) Alexander J Sercel et al.   eLife

Extracellular Mitochondria Signals in CNS Disorders

(2021) Ji-Hyun Park et al.   Frontiers in Cell and Developmental Biology

Miro proteins connect mitochondrial function and intercellular transport

(2021) Zuzana Nahacka et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mitochondrial dysfunction and apoptosis are attenuated through activation of AMPK/GSK-3β/PP2A pathway in Parkinson's disease

(2021) Jianhua Su et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mitochondria Can Cross Cell Boundaries: An Overview of the Biological Relevance, Pathophysiological Implications and Therapeutic Perspectives of Intercellular Mitochondrial Transfer

(2021) Daniela Valenti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Conditional disruption of AMP kinase in dopaminergic neurons promotes Parkinson's disease-associated phenotypes in vivo

(2021) Liting Hang et al.   NEUROBIOLOGY OF DISEASE

Mitochondrial dysfunction in a mouse model of prodromal Parkinson’s disease: A metabolomic analysis

(2021) Masashi Ikuno et al.   NEUROSCIENCE LETTERS

Mitochondrial Extracellular Vesicles – Origins and Roles

(2021) Lydia Amari et al.   Frontiers in Molecular Neuroscience

Neuroprotection from optic nerve injury and modulation of oxidative metabolism by transplantation of active mitochondria to the retina

(2020) Gabriel Nascimento-dos-Santos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Activation of PGC-1α and Mitochondrial Biogenesis Protects Against Prenatal Hypoxic–ischemic Brain Injury

(2020) Lijie Jia et al.   NEUROSCIENCE

Human iPSCs derived astrocytes rescue rotenone-induced mitochondrial dysfunction and dopaminergic neurodegeneration in vitro by donating functional mitochondria

(2020) Xiao-Yu Cheng et al.   Translational Neurodegeneration

Inter and Intracellular mitochondrial trafficking in health and disease

(2020) Santhanam Shanmughapriya et al.   AGEING RESEARCH REVIEWS

Challenges in Promoting Mitochondrial Transplantation Therapy

(2020) Yuma Yamada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mesenchymal Stem Cell-Mediated Mitochondrial Transfer: a Therapeutic Approach for Ischemic Stroke

(2020) Meng Lu et al.   Translational Stroke Research

The Emerging Role of RHOT1/Miro1 in the Pathogenesis of Parkinson's Disease

(2020) Dajana Grossmann et al.   Frontiers in Neurology

Autologous mitochondrial transplantation for cardiogenic shock in pediatric patients following ischemia-reperfusion injury

(2020) Alvise Guariento et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Mitochondrial Dysfunction and Mitophagy in Parkinson’s Disease: From Mechanism to Therapy

(2020) Ana Belen Malpartida et al.   TRENDS IN BIOCHEMICAL SCIENCES

Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates

(2020) Alexander N. Patananan et al.   Cell Reports

Mitochondrial Transfer and Regulators of Mesenchymal Stromal Cell Function and Therapeutic Efficacy

(2020) Amina Mohammadalipour et al.   Frontiers in Cell and Developmental Biology

Pathogenic alpha-synuclein aggregates preferentially bind to mitochondria and affect cellular respiration

(2019) Xinhe Wang et al.   Acta Neuropathologica Communications

Further investigation of mitochondrial biogenesis and gene expression of key regulators in ascites- susceptible and ascites- resistant broiler research lines

(2019) Khaloud Al-Zahrani et al.   PLoS One

The Energy Homeostasis Principle: Neuronal Energy Regulation Drives Local Network Dynamics Generating Behavior

(2019) Rodrigo C. Vergara et al.   Frontiers in Computational Neuroscience

Current progress of mitochondrial transplantation that promotes neuronal regeneration

(2019) Chu-Yuan Chang et al.   Translational Neurodegeneration

Intracellular and Intercellular Mitochondrial Dynamics in Parkinson’s Disease

(2019) Dario Valdinocci et al.   Frontiers in Neuroscience

Voluntary exercise delays progressive deterioration of markers of metabolism and behavior in a mouse model of Parkinson’s disease

(2019) Jing-Huei Lai et al.   BRAIN RESEARCH

ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection

(2019) Jayna J. Mistry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Dysfunction in Parkinson’s Disease: New Mechanistic Insights and Therapeutic Perspectives

(2018) Jin-Sung Park et al.   Current Neurology and Neuroscience Reports

Alloreactivity and allorecognition of syngeneic and allogeneic mitochondria

(2018) Giovanna Ramirez-Barbieri et al.   MITOCHONDRION

α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies

(2018) Iryna Prots et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Miro—Working beyond Mitochondria and Microtubules

(2018) Bor Tang   Cells

Plasmid-normalized quantification of relative mitochondrial DNA copy number

(2018) Federica Fazzini et al.   Scientific Reports

Myocardial rescue with autologous mitochondrial transplantation in a porcine model of ischemia/reperfusion

(2017) Aditya K. Kaza et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Mitochondrial transplantation: From animal models to clinical use in humans

(2017) James D. McCully et al.   MITOCHONDRION

Intravenous administration of mitochondria for treating experimental Parkinson's disease

(2017) Xianxun Shi et al.   MITOCHONDRION

Live birth derived from oocyte spindle transfer to prevent mitochondrial disease

(2017) John Zhang et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Transferring Xenogenic Mitochondria Provides Neural Protection against Ischemic Stress in Ischemic Rat Brains

(2016) Po-Jui Huang et al.   CELL TRANSPLANTATION

Extracellular vesicles and intercellular communication within the nervous system

(2016) Valentina Zappulli et al.   JOURNAL OF CLINICAL INVESTIGATION

Transfer of mitochondria from astrocytes to neurons after stroke

(2016) Kazuhide Hayakawa et al.   NATURE

Allogeneic/xenogeneic transplantation of peptide-labeled mitochondria in Parkinson's disease: restoration of mitochondria functions and attenuation of 6-hydroxydopamine–induced neurotoxicity

(2016) Jui-Chih Chang et al.   Translational Research

Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons

(2015) Consiglia Pacelli et al.   CURRENT BIOLOGY

Regulation of mitochondrial transport in neurons

(2015) Mei-Yao Lin et al.   EXPERIMENTAL CELL RESEARCH

Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease

(2015) Dominik Haddad et al.   FEBS LETTERS

Coenzyme Q10 Protects Astrocytes from ROS-Induced Damage through Inhibition of Mitochondria-Mediated Cell Death Pathway

(2015) Li Jing et al.   International Journal of Biological Sciences

Exercise modulates liver cellular and mitochondrial proteins related to quality control signaling

(2015) E. Santos-Alves et al.   LIFE SCIENCES

Ginsenoside Rg1 Ameliorates Motor Function in an Animal Model of Parkinson's Disease

(2015) Wenda Jiang et al.   PHARMACOLOGY

Glitazone Treatment and Incidence of Parkinson’s Disease among People with Diabetes: A Retrospective Cohort Study

(2015) Ruth Brauer et al.   PLOS MEDICINE

MIRO GTPases in Mitochondrial Transport, Homeostasis and Pathology

(2015) Bor Tang   Cells

High-Fat Diet–Induced Mitochondrial Biogenesis Is Regulated by Mitochondrial-Derived Reactive Oxygen Species Activation of CaMKII

(2014) Swati S. Jain et al.   DIABETES

Physical exercise prevents and mitigates non-alcoholic steatohepatitis-induced liver mitochondrial structural and bioenergetics impairments

(2014) Inês O. Gonçalves et al.   MITOCHONDRION

Mitochondrial dynamics and inheritance during cell division, development and disease

(2014) Prashant Mishra et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cytoplasmic dynein: a key player in neurodegenerative and neurodevelopmental diseases

(2014) Xiang-Jun Chen et al.   Science China-Life Sciences

Transplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury

(2013) Akihiro Masuzawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Terminal Axon Branching Is Regulated by the LKB1-NUAK1 Kinase Pathway via Presynaptic Mitochondrial Capture

(2013) Julien Courchet et al.   CELL

AMP-activated protein kinase mediates activity-dependent axon branching by recruiting mitochondria to axon

(2013) Kentaro Tao et al.   Developmental Neurobiology

TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites

(2013) Myrrhe van Spronsen et al.   NEURON

When Cells Become Organelle Donors

(2013) Robert S. Rogers et al.   PHYSIOLOGY

Miro, MCU, and calcium: bridging our understanding of mitochondrial movement in axons

(2013) Robert F. Niescier et al.   Frontiers in Cellular Neuroscience

Mitochondrial Biology and Parkinson's Disease

(2013) C. Perier et al.   Cold Spring Harbor Perspectives in Medicine

Maternal exercise during pregnancy affects mitochondrial enzymatic activity and biogenesis in offspring brain

(2012) Jong-won Park et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Living on the edge with too many mouths to feed: Why dopamine neurons die

(2012) J. Paul Bolam et al.   MOVEMENT DISORDERS

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

(2012) Mohammad Naimul Islam et al.   NATURE MEDICINE

Tunneling-nanotube direction determination in neurons and astrocytes

(2012) X Sun et al.   Cell Death & Disease

Skeletal muscle and beyond: the role of exercise as a mediator of systemic mitochondrial biogenesis

(2011) Jonathan P. Little et al.   Applied Physiology Nutrition and Metabolism

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

(2011) Xinnan Wang et al.   CELL

Exercise training increases mitochondrial biogenesis in the brain

(2011) Jennifer L. Steiner et al.   JOURNAL OF APPLIED PHYSIOLOGY

Glucagon and lipid interactions in the regulation of hepatic AMPK signaling and expression of PPARα and FGF21 transcripts in vivo

(2010) Eric D. Berglund et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Regulation of mitochondrial biogenesis

(2010) François R. Jornayvaz et al.   Essays in Biochemistry

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

(2010) Seok Min Jin et al.   JOURNAL OF CELL BIOLOGY

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

The Mechanism of Ca2+-Dependent Regulation of Kinesin-Mediated Mitochondrial Motility

(2009) Xinnan Wang et al.   CELL

Human Myo19 Is a Novel Myosin that Associates with Mitochondria

(2009) Omar A. Quintero et al.   CURRENT BIOLOGY

AMPK in the brain: its roles in energy balance and neuroprotection

(2009) Gabriele V. Ronnett et al.   JOURNAL OF NEUROCHEMISTRY

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Miro1 Is a Calcium Sensor for Glutamate Receptor-Dependent Localization of Mitochondria at Synapses

(2009) Andrew F. MacAskill et al.   NEURON

A neuron-specific cytoplasmic dynein isoform preferentially transports TrkB signaling endosomes

(2008) Junghoon Ha et al.   JOURNAL OF CELL BIOLOGY

Assessing mitochondria biogenesis

(2008) Denis M. Medeiros   METHODS