β-Catenin Is Required for the cGAS/STING Signaling Pathway but Antagonized by the Herpes Simplex Virus 1 US3 Protein

Herpes Simplex Virus 1 Tegument Protein UL46 Inhibits TANK-Binding Kinase 1-Mediated Signaling

(2019) Hongjuan You et al.   mBio

β-catenin regulates IRF3-mediated innate immune signalling in colorectal cancer

(2018) Chengming Ding et al.   CELL PROLIFERATION

Herpes Simplex Virus 1 Tegument Protein VP22 Abrogates cGAS/STING-Mediated Antiviral Innate Immunity

(2018) Jian Huang et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus 1 Abrogates the cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway via Its Virion Host Shutoff Protein, UL41

(2017) Chenhe Su et al.   JOURNAL OF VIROLOGY

The UL13 and US3 Protein Kinases of Herpes Simplex Virus 1 Cooperate to Promote the Assembly and Release of Mature, Infectious Virions

(2015) Svetlana Gershburg et al.   PLoS One

β-catenin promotes the type I IFN synthesis and the IFN-dependent signaling response but is suppressed by influenza A virus-induced RIG-I/NF-κB signaling

(2014) Andrea Hillesheim et al.   Cell Communication and Signaling

Herpes Simplex Virus 1 Protein Kinase US3 Hyperphosphorylates p65/RelA and Dampens NF-κB Activation

(2014) Kezhen Wang et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus 1 Counteracts Viperin via Its Virion Host Shutoff Protein UL41

(2014) G. Shen et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus 1 Serine/Threonine Kinase US3 Hyperphosphorylates IRF3 and Inhibits Beta Interferon Production

(2013) Shuai Wang et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus 1 E3 Ubiquitin Ligase ICP0 Protein Inhibits Tumor Necrosis Factor Alpha-Induced NF-κB Activation by Interacting with p65/RelA and p50/NF-κB1

(2013) Jie Zhang et al.   JOURNAL OF VIROLOGY

Us3 Kinase Encoded by Herpes Simplex Virus 1 Mediates Downregulation of Cell Surface Major Histocompatibility Complex Class I and Evasion of CD8+ T Cells

(2013) Takahiko Imai et al.   PLoS One

The Akt1 Isoform Is Required for Optimal IFN-  Transcription through Direct Phosphorylation of  -Catenin

(2012) B. N. Gantner et al.   JOURNAL OF IMMUNOLOGY

Human Immunodeficiency Virus Type 1 (HIV-1) Transactivator of Transcription through Its Intact Core and Cysteine-Rich Domains Inhibits Wnt/ -Catenin Signaling in Astrocytes: Relevance to HIV Neuropathogenesis

(2012) L. J. Henderson et al.   JOURNAL OF NEUROSCIENCE

Herpes Simplex Virus 1 Tegument Protein US11 Downmodulates the RLR Signaling Pathway via Direct Interaction with RIG-I and MDA-5

(2012) J. Xing et al.   JOURNAL OF VIROLOGY

The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response

(2012) Kislay Parvatiyar et al.   NATURE IMMUNOLOGY

Modulation of GSK-3β Activity in Venezuelan Equine Encephalitis Virus Infection

(2012) Kylene Kehn-Hall et al.   PLoS One

Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

(2012) J. Wu et al.   SCIENCE

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

(2012) L. Sun et al.   SCIENCE

Human Cytomegalovirus Infection Dysregulates the Canonical Wnt/β-catenin Signaling Pathway

(2012) Magdalena Angelova et al.   PLoS Pathogens

How do they do Wnt they do?: regulation of transcription by the Wnt/β-catenin pathway

(2011) H. C. Archbold et al.   Acta Physiologica

PKC alpha regulates Sendai virus-mediated interferon induction through HDAC6 and β-catenin

(2011) Jianzhong Zhu et al.   EMBO JOURNAL

Varicella-Zoster Virus Immediate-Early Protein ORF61 Abrogates the IRF3-Mediated Innate Immune Response through Degradation of Activated IRF3

(2011) H. Zhu et al.   JOURNAL OF VIROLOGY

The STING pathway and regulation of innate immune signaling in response to DNA pathogens

(2010) Hiroki Ishikawa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replication

(2010) U. Chuluunbaatar et al.   GENES & DEVELOPMENT

Comprehensive Characterization of Interaction Complexes of Herpes Simplex Virus Type 1 ICP22, UL3, UL4, and UL20.5

(2010) J. Xing et al.   JOURNAL OF VIROLOGY

The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a β-catenin-dependent pathway

(2010) Pengyuan Yang et al.   NATURE IMMUNOLOGY

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

Molecular anatomy of subcellular localization of HSV-1 tegument protein US11 in living cells

(2010) Junji Xing et al.   VIRUS RESEARCH

A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection

(2009) Sagi D. Shapira et al.   CELL

Molecular cloning and functional characterization of porcine DNA-dependent activator of IFN-regulatory factors (DAI)

(2009) Lilan Xie et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Innate Immune Recognition of Viruses and Viral Vectors

(2009) Xiaopei Huang et al.   HUMAN GENE THERAPY