Mechanisms of circular RNA degradation

Digital multiplexed analysis of circular RNAs in FFPE and fresh non‐small cell lung cancer specimens

(2022) Carlos Pedraz‐Valdunciel et al.   Molecular Oncology

Circular RNAs: Characterization, cellular roles, and applications

(2022) Chu-Xiao Liu et al.   CELL

Circular RNA vaccines against SARS-CoV-2 and emerging variants

(2022) Liang Qu et al.   CELL

A novel peptide encoded by N6-methyladenosine modified circMAP3K4 prevents apoptosis in hepatocellular carcinoma

(2022) Jin-Ling Duan et al.   Molecular Cancer

Context-specific effects of sequence elements on subcellular localization of linear and circular RNAs

(2022) Maya Ron et al.   Nature Communications

EIF4A3-mediated circPRKCI expression promotes triple-negative breast cancer progression by regulating WBP2 and PI3K/AKT signaling pathway

(2022) Xuehui Wang et al.   Cell Death Discovery

Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs

(2022) Karoline E. Kokot et al.   BASIC RESEARCH IN CARDIOLOGY

Exportin 4 depletion leads to nuclear accumulation of a subset of circular RNAs

(2022) Liang Chen et al.   Nature Communications

PKR activity modulation by phosphomimetic mutations of serine residues located three aminoacids upstream of double-stranded RNA binding motifs

(2021) Teresa Cesaro et al.   Scientific Reports

Circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer: involvement of miR-30c-5p/TCF7 axis

(2021) Yaxin Guo et al.   Molecular Cancer

NOVA2 regulates neural circRNA biogenesis

(2021) David Knupp et al.   NUCLEIC ACIDS RESEARCH

Linking circular intronic RNA degradation and function in transcription by RNase H1

(2021) Xiang Li et al.   Science China-Life Sciences

An autoregulation loop in fust-1 for circular RNA regulation in Caenorhabditis elegans

(2021) Dong Cao   GENETICS

A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota

(2021) Yinrui Guo et al.   Translational Psychiatry

RNase L limits host and viral protein synthesis via inhibition of mRNA export

(2021) James M. Burke et al.   Science Advances

The circular RNA circSLC7A11 functions as a mir-330-3p sponge to accelerate hepatocellular carcinoma progression by regulating cyclin-dependent kinase 1 expression

(2021) Yu Huang et al.   Cancer Cell International

Circular RNA CircHIPK3 Promotes Homeostasis of the Intestinal Epithelium by Reducing MicroRNA 29b Function

(2021) Lan Xiao et al.   GASTROENTEROLOGY

Angiogenesis is Inhibited by Arsenic Trioxide Through Downregulation of the CircHIPK3/miR-149-5p/FOXO1/VEGF Functional Module in Rheumatoid Arthritis

(2021) Juan Zhang et al.   Frontiers in Pharmacology

circACTR2: A Novel Mechanism Regulating High Glucose-Induced Fibrosis in Renal Tubular Cells via Pyroptosis

(2020) Si Wen et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Genome-wide integrative analysis of circular RNA dysregulation and the corresponding circular RNA-microRNA-mRNA regulatory axes in autism

(2020) Yen-Ju Chen et al.   GENOME RESEARCH

Translation and functional roles of circular RNAs in human cancer

(2020) Ming Lei et al.   Molecular Cancer

Structure-Mediated RNA Decay by UPF1 and G3BP1

(2020) Joseph W. Fischer et al.   MOLECULAR CELL

Novel insights into m6A modification in circular RNA and implications for immunity

(2020) Arumugam Paramasivam et al.   Cellular & Molecular Immunology

Circular RNA-ZNF532 regulates diabetes-induced retinal pericyte degeneration and vascular dysfunction

(2020) Qin Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of N6-methyladenosine (m6A) modification in the regulation of circRNAs

(2020) Lele Zhang et al.   Molecular Cancer

TMAO: how gut microbiota contributes to heart failure

(2020) Yixin Zhang et al.   Translational Research

Hsa_circ_0012152 and Hsa_circ_0001857 Accurately Discriminate Acute Lymphoblastic Leukemia From Acute Myeloid Leukemia

(2020) Shanshan Guo et al.   Frontiers in Oncology

Circular RNA: metabolism, functions and interactions with proteins

(2020) Wei-Yi Zhou et al.   Molecular Cancer

N6-methyladenosine-modified CircRNA-SORE sustains sorafenib resistance in hepatocellular carcinoma by regulating β-catenin signaling

(2020) Junjie Xu et al.   Molecular Cancer

YAP Circular RNA, circYap, Attenuates Cardiac Fibrosis via Binding with Tropomyosin-4 and Gamma-Actin Decreasing Actin Polymerization

(2020) Nan Wu et al.   MOLECULAR THERAPY

MicroRNA-1224 splicing circularRNA-Filip1l in an Ago2- dependent manner regulates chronic inflammatory pain via targeting Ubr5

(2019) Zhiqiang Pan et al.   JOURNAL OF NEUROSCIENCE

Circular RNA Profiling by Illumina Sequencing via Template-Dependent Multiple Displacement Amplification

(2019) Ashirbad Guria et al.   Biomed Research International

Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex

(2019) Ok Hyun Park et al.   MOLECULAR CELL

RNA-seq of circular RNAs identified circPTPN22 as a potential new activity indicator in systemic lupus erythematosus

(2019) Q Miao et al.   LUPUS

Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity

(2019) Chu-Xiao Liu et al.   CELL

Circular RNAs and RNase L in PKR activation and virus infection

(2019) Zhi-Ming Zheng   Cell and Bioscience

Circular RNA circHIPK3 modulates autophagy via MIR124-3p-STAT3-PRKAA/AMPKα signaling in STK11 mutant lung cancer

(2019) Xiuyuan Chen et al.   Autophagy

Circular RNA TLK1 aggravates neuronal injury and neurological deficits after ischemic stroke via miR-335-3p/TIPARP

(2019) Fangfang Wu et al.   JOURNAL OF NEUROSCIENCE

A unified mechanism for intron and exon definition and back-splicing

(2019) Xueni Li et al.   NATURE

The biogenesis, biology and characterization of circular RNAs

(2019) Lasse S. Kristensen et al.   NATURE REVIEWS GENETICS

NUDT21 regulates circRNA cyclization and ceRNA crosstalk in hepatocellular carcinoma

(2019) Xiaojing Li et al.   ONCOGENE

Defining an evolutionarily conserved role of GW182 in circular RNA degradation

(2019) Ruirui Jia et al.   Cell Discovery

Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis

(2019) Venkata Naga Srikanth Garikipati et al.   Nature Communications

N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis

(2019) Ri-Xin Chen et al.   Nature Communications

The AGO proteins: an overview

(2018) Saife Niaz   BIOLOGICAL CHEMISTRY

Microarray is an efficient tool for circRNA profiling

(2018) Shasha Li et al.   BRIEFINGS IN BIOINFORMATICS

A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs

(2018) Chuan Huang et al.   GENES & DEVELOPMENT

Size matters: conserved proteins function in length-dependent nuclear export of circular RNAs

(2018) Yao Wan et al.   GENES & DEVELOPMENT

Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma

(2018) Jian Yu et al.   JOURNAL OF HEPATOLOGY

A-to-I RNA editing — immune protector and transcriptome diversifier

(2018) Eli Eisenberg et al.   NATURE REVIEWS GENETICS

circHIPK3 regulates cell proliferation and migration by sponging miR-124 and regulating AQP3 expression in hepatocellular carcinoma

(2018) Genwen Chen et al.   Cell Death & Disease

CircHIPK3 promotes proliferation and invasion in nasopharyngeal carcinoma by abrogating miR-4288-induced ELF3 inhibition

(2018) Zhaoyang Ke et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Circular RNA HIPK3 exerts oncogenic properties through suppression of miR-124 in lung cancer

(2018) Hanqing Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Coordinated circRNA Biogenesis and Function with NF90/NF110 in Viral Infection

(2017) Xiang Li et al.   MOLECULAR CELL

DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome

(2017) Tuğçe Aktaş et al.   NATURE

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

(2017) Monika Piwecka et al.   SCIENCE

FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons

(2017) Lorenzo Errichelli et al.   Nature Communications

Detecting circular RNAs: bioinformatic and experimental challenges

(2016) Linda Szabo et al.   NATURE REVIEWS GENETICS

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

The Biogenesis of Nascent Circular RNAs

(2016) Yang Zhang et al.   Cell Reports

Circular RNAs Co-Precipitate with Extracellular Vesicles: A Possible Mechanism for circRNA Clearance

(2016) Erika Lasda et al.   PLoS One

The RNA Binding Protein Quaking Regulates Formation of circRNAs

(2015) Simon J. Conn et al.   CELL

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

(2015) Yan Li et al.   CELL RESEARCH

Combinatorial control ofDrosophilacircular RNA expression by intronic repeats, hnRNPs, and SR proteins

(2015) Marianne C. Kramer et al.   GENES & DEVELOPMENT

Circular RNAs are long-lived and display only minimal early alterations in response to a growth factor

(2015) Yehoshua Enuka et al.   NUCLEIC ACIDS RESEARCH

Exon Circularization Requires Canonical Splice Signals

(2015) Stefan Starke et al.   Cell Reports

Correlation of circular RNA abundance with proliferation – exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis and normal human tissues

(2015) Anna Bachmayr-Heyda et al.   Scientific Reports

miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA

(2011) Thomas B Hansen et al.   EMBO JOURNAL