A unified mechanism for intron and exon definition and back-splicing

RNAs in the spliceosome: Insight from cryoEM structures

(2019) Lingdi Zhang et al.   Wiley Interdisciplinary Reviews-RNA

Insights into the biogenesis and potential functions of exonic circular RNA

(2019) Chikako Ragan et al.   Scientific Reports

Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching

(2019) Ruixue Wan et al.   CELL

Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation

(2018) Rui Bai et al.   SCIENCE

A 360° view of circular RNAs: From biogenesis to functions

(2018) Jeremy E. Wilusz   Wiley Interdisciplinary Reviews-RNA

Prespliceosome structure provides insights into spliceosome assembly and regulation

(2018) Clemens Plaschka et al.   NATURE

De novo computational RNA modeling into cryo-EM maps of large ribonucleoprotein complexes

(2018) Kalli Kappel et al.   NATURE METHODS

Sampling Native-like Structures of RNA-Protein Complexes through Rosetta Folding and Docking

(2018) Kalli Kappel et al.   STRUCTURE

The Output of Protein-Coding Genes Shifts to Circular RNAs When the Pre-mRNA Processing Machinery Is Limiting

(2017) Dongming Liang et al.   MOLECULAR CELL

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Structure of the yeast spliceosomal postcatalytic P complex

(2017) Shiheng Liu et al.   SCIENCE

CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing

(2017) Xueni Li et al.   Nature Communications

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

xVis: a web server for the schematic visualization and interpretation of crosslink-derived spatial restraints

(2015) Maximilian Grimm et al.   NUCLEIC ACIDS RESEARCH

Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs

(2015) Agata Jacewicz et al.   RNA

Sequencing of lariat termini inS. cerevisiaereveals 5′ splice sites, branch points, and novel splicing events

(2015) Daoming Qin et al.   RNA

Exon Circularization Requires Canonical Splice Signals

(2015) Stefan Starke et al.   Cell Reports

Short intronic repeat sequences facilitate circular RNA production

(2014) Dongming Liang et al.   GENES & DEVELOPMENT

Circular RNA Is Expressed across the Eukaryotic Tree of Life

(2014) Peter L. Wang et al.   PLoS One

Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7within the Carboxyl-terminal Domain Repeat

(2013) Jiangxin Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly

(2013) Xueni Li et al.   NUCLEIC ACIDS RESEARCH

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

RCrane: semi-automated RNA model building

(2012) Kevin S. Keating et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MetaDisorder: a meta-server for the prediction of intrinsic disorder in proteins

(2012) Lukasz P Kozlowski et al.   BMC BIOINFORMATICS

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

Correcting pervasive errors in RNA crystallography through enumerative structure prediction

(2012) Fang-Chieh Chou et al.   NATURE METHODS

Genetic interactions of hypomorphic mutations in the m7G cap-binding pocket of yeast nuclear cap binding complex: An essential role for Cbc2 in meiosis via splicing of MER3 pre-mRNA

(2012) Z. R. Qiu et al.   RNA

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

Exon and intron definition in pre-mRNA splicing

(2012) Laura De Conti et al.   Wiley Interdisciplinary Reviews-RNA

Cotranscriptional spliceosome assembly and splicing are independent of the Prp40p WW domain

(2011) J. Gornemann et al.   RNA

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Exon Definition Complexes Contain the Tri-snRNP and Can Be Directly Converted into B-like Precatalytic Splicing Complexes

(2010) Marc Schneider et al.   MOLECULAR CELL

Conformational dynamics of single pre-mRNA molecules during in vitro splicing

(2010) John Abelson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries

(2010) Michal Mokry et al.   NUCLEIC ACIDS RESEARCH

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal Structure of the Three Tandem FF Domains of the Transcription Elongation Regulator CA150

(2009) Ming Lu et al.   JOURNAL OF MOLECULAR BIOLOGY

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

The FF domains of yeast U1 snRNP protein Prp40 mediate interactions with Luc7 and Snu71

(2008) Claudia Ester et al.   BMC BIOCHEMISTRY

Polypyrimidine tract binding protein controls the transition from exon definition to an intron defined spliceosome

(2008) Shalini Sharma et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY