Translation and functional roles of circular RNAs in human cancer

A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling

(2019) Xiao Zheng et al.   Molecular Cancer

The circular RNome of primary breast cancer

(2019) Marcel Smid et al.   GENOME RESEARCH

The Landscape of Circular RNA in Cancer

(2019) Josh N. Vo et al.   CELL

Widespread and Functional RNA Circularization in Localized Prostate Cancer

(2019) Sujun Chen et al.   CELL

Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression

(2019) Xiaoxu Huang et al.   Molecular Cancer

The Translational Landscape of the Human Heart

(2019) Sebastiaan van Heesch et al.   CELL

CircCode: A Powerful Tool for Identifying circRNA Coding Ability

(2019) Peisen Sun et al.   Frontiers in Genetics

circFBXW7 Inhibits Malignant Progression by Sponging miR-197-3p and Encoding a 185-aa Protein in Triple-Negative Breast Cancer

(2019) Feng Ye et al.   Molecular Therapy-Nucleic Acids

Down-regulation of hsa_circ_0001649 in hepatocellular carcinoma predicts a poor prognosis

(2018) Xianwei Zhang et al.   Cancer Biomarkers

The emerging functions and roles of circular RNAs in cancer

(2018) Shibin Qu et al.   CANCER LETTERS

A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain

(2018) Benjamin Kleaveland et al.   CELL

A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs

(2018) Chuan Huang et al.   GENES & DEVELOPMENT

N 6 -Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response

(2018) Jun Zhou et al.   MOLECULAR CELL

A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis

(2018) Maolei Zhang et al.   ONCOGENE

Circular RNA expression in human hematopoietic cells is widespread and cell-type specific

(2018) Benoit P Nicolet et al.   NUCLEIC ACIDS RESEARCH

Circular RNA expression profiles during the differentiation of mouse neural stem cells

(2018) Qichang Yang et al.   BMC Systems Biology

The Pfam protein families database in 2019

(2018) Sara El-Gebali et al.   NUCLEIC ACIDS RESEARCH

A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma

(2018) Maolei Zhang et al.   Nature Communications

Circular RNA circMTO1 acts as the sponge of microRNA-9 to suppress hepatocellular carcinoma progression

(2017) Dan Han et al.   HEPATOLOGY

A map of human circular RNAs in clinically relevant tissues

(2017) Philipp G. Maass et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis

(2017) Yibing Yang et al.   JNCI-Journal of the National Cancer Institute

Circular RNAs in human cancer

(2017) Yumin Wang et al.   Molecular Cancer

Translation of CircRNAs

(2017) Nagarjuna Reddy Pamudurti et al.   MOLECULAR CELL

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

(2017) Ivano Legnini et al.   MOLECULAR CELL

Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1

(2017) Kotb Abdelmohsen et al.   RNA Biology

A comprehensive overview and evaluation of circular RNA detection tools

(2017) Xiangxiang Zeng et al.   PLoS Computational Biology

Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis

(2017) Yibing Yang et al.   JNCI-Journal of the National Cancer Institute

Hsa_circ_0001649: A circular RNA and potential novel biomarker for hepatocellular carcinoma

(2016) Meilin Qin et al.   Cancer Biomarkers

Detecting circular RNAs: bioinformatic and experimental challenges

(2016) Linda Szabo et al.   NATURE REVIEWS GENETICS

Insights into the mechanisms of eukaryotic translation gained with ribosome profiling

(2016) Dmitry E. Andreev et al.   NUCLEIC ACIDS RESEARCH

Visualization of self-delivering hydrophobically modified siRNA cellular internalization

(2016) Socheata Ly et al.   NUCLEIC ACIDS RESEARCH

Increased complexity of circRNA expression during species evolution

(2016) Rui Dong et al.   RNA Biology

CircRNAs in the brain

(2016) Mor Hanan et al.   RNA Biology

Circular RNAs: Unexpected outputs of many protein-coding genes

(2016) Jeremy E. Wilusz   RNA Biology

The emerging landscape of circular RNA in life processes

(2016) Shibin Qu et al.   RNA Biology

Translational control by 5'-untranslated regions of eukaryotic mRNAs

(2016) A. G. Hinnebusch et al.   SCIENCE

Systematic discovery of cap-independent translation sequences in human and viral genomes

(2016) Shira Weingarten-Gabbay et al.   SCIENCE

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

circRNADb: A comprehensive database for human circular RNAs with protein-coding annotations

(2016) Xiaoping Chen et al.   Scientific Reports

5′ UTR m6A Promotes Cap-Independent Translation

(2015) Kate D. Meyer et al.   CELL

FusionCancer: a database of cancer fusion genes derived from RNA-seq data

(2015) Yunjin Wang et al.   Diagnostic Pathology

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

(2015) Agnieszka Rybak-Wolf et al.   MOLECULAR CELL

Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity

(2015) Xintian You et al.   NATURE NEUROSCIENCE

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA circularization strategies in vivo and in vitro

(2015) Sonja Petkovic et al.   NUCLEIC ACIDS RESEARCH

Comparison of circular RNA prediction tools

(2015) Thomas B. Hansen et al.   NUCLEIC ACIDS RESEARCH

Deciphering the RNA landscape by RNAome sequencing

(2015) Kasper WJ Derks et al.   RNA Biology

CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs

(2015) Dawood B. Dudekula et al.   RNA Biology

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rolling Circle Translation of Circular RNA in Living Human Cells

(2015) Naoko Abe et al.   Scientific Reports

Analysis of Intron Sequences Reveals Hallmarks of Circular RNA Biogenesis in Animals

(2015) Andranik Ivanov et al.   Cell Reports

The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells

(2015) Huanyu Xu et al.   Scientific Reports

Complementary Sequence-Mediated Exon Circularization

(2014) Xiao-Ou Zhang et al.   CELL

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

Detecting and characterizing circular RNAs

(2014) William R Jeck et al.   NATURE BIOTECHNOLOGY

Circular RNA Is Expressed across the Eukaryotic Tree of Life

(2014) Peter L. Wang et al.   PLoS One

circBase: a database for circular RNAs

(2014) Petar Glažar et al.   RNA

Efficient backsplicing produces translatable circular mRNAs

(2014) Yang Wang et al.   RNA

Genome-wide Analysis of Drosophila Circular RNAs Reveals Their Structural and Sequence Properties and Age-Dependent Neural Accumulation

(2014) Jakub O. Westholm et al.   Cell Reports

A multi-split mapping algorithm for circular RNA, splicing, trans-splicing and fusion detection

(2014) Steve Hoffmann et al.   GENOME BIOLOGY

Circular RNA and miR-7 in Cancer

(2013) T. B. Hansen et al.   CANCER RESEARCH

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model

(2013) Liguo Wang et al.   NUCLEIC ACIDS RESEARCH

ceRNA Cross-Talk in Cancer: When ce-bling Rivalries Go Awry

(2013) F. A. Karreth et al.   Cancer Discovery

Cell-Type Specific Features of Circular RNA Expression

(2013) Julia Salzman et al.   PLoS Genetics

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

(2012) Julia Salzman et al.   PLoS One

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions

(2011) M. F. Lin et al.   BIOINFORMATICS

Cap- and IRES-independent scanning mechanism of translation initiation as an alternative to the concept of cellular IRESs

(2010) Ivan N. Shatsky et al.   MOLECULES AND CELLS

Beta-catenin signaling, liver regeneration and hepatocellular cancer: Sorting the good from the bad

(2010) Kari Nichole Nejak-Bowen et al.   SEMINARS IN CANCER BIOLOGY

Topology and Regulation of the Human eIF4A/4G/4H Helicase Complex in Translation Initiation

(2009) Assen Marintchev et al.   CELL

IRESite—a tool for the examination of viral and cellular internal ribosome entry sites

(2009) Martin Mokrejš et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Crystal structure of the yeast eIF4A-eIF4G complex: An RNA-helicase controlled by protein-protein interactions

(2008) P. Schutz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Re-programming of translation following cell stress allows IRES-mediated translation to predominate

(2007) Keith A. Spriggs et al.   BIOLOGY OF THE CELL