The Tumor Microenvironment in Tumorigenesis and Therapy Resistance Revisited
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Title
The Tumor Microenvironment in Tumorigenesis and Therapy Resistance Revisited
Authors
Keywords
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Journal
Cancers
Volume 15, Issue 2, Pages 376
Publisher
MDPI AG
Online
2023-01-06
DOI
10.3390/cancers15020376
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Note: Only part of the references are listed.- Highly‐metastatic colorectal cancer cell released miR‐181a‐5p‐rich extracellular vesicles promote liver metastasis by activating hepatic stellate cells and remodelling the tumour microenvironment
- (2022) Senlin Zhao et al. Journal of Extracellular Vesicles
- B-Cell-Based Immunotherapy: A Promising New Alternative
- (2022) Sneh Lata Gupta et al. Vaccines
- New insights into antiangiogenic therapy resistance in cancer: Mechanisms and therapeutic aspects
- (2022) Maohua Huang et al. DRUG RESISTANCE UPDATES
- Role of B cells as antigen presenting cells
- (2022) Ichwaku Rastogi et al. Frontiers in Immunology
- T Cells in Chronic Lymphocytic Leukemia: A Two-Edged Sword
- (2021) Elisavet Vlachonikola et al. Frontiers in Immunology
- The Role of Stellate Cells in Pancreatic Ductal Adenocarcinoma: Targeting Perspectives
- (2021) Yang Wu et al. Frontiers in Oncology
- Metabolic reprogramming of T regulatory cells in the hypoxic tumor microenvironment
- (2021) Varun Sasidharan Nair et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- CXCR1 correlates to poor outcomes of EGFR-TKI against advanced non-small cell lung cancer by activating chemokine and JAK/STAT pathway
- (2021) Fang Yang et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Immunosuppressive Mechanisms of Regulatory B Cells
- (2021) Diego Catalán et al. Frontiers in Immunology
- Clinical Relevance of CD4 Cytotoxic T Cells in High-Risk Neuroblastoma
- (2021) Xao X. Tang et al. Frontiers in Immunology
- Tumor microenvironment in triple-negative breast cancer: the correlation of tumor-associated macrophages and tumor-infiltrating lymphocytes
- (2021) H. Kuroda et al. Clinical & Translational Oncology
- New insights into B cells as antigen presenting cells
- (2021) Debopam Ghosh et al. CURRENT OPINION IN IMMUNOLOGY
- Tumor-associated neutrophils: orchestrating cancer pathobiology and therapeutic resistance
- (2021) Triet M. Bui et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Neutrophils in Tumorigenesis: Missing Targets for Successful Next Generation Cancer Therapies?
- (2021) Fabrice Tolle et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Chemokine-Directed Tumor Microenvironment Modulation in Cancer Immunotherapy
- (2021) Pedro Bule et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Regulatory T cell and neutrophil extracellular trap interaction contributes to carcinogenesis in non-alcoholic steatohepatitis
- (2021) Han Wang et al. JOURNAL OF HEPATOLOGY
- The Role of Plasmacytoid Dendritic Cells in Cancers
- (2021) Binhui Zhou et al. Frontiers in Immunology
- Regulation of T Cells in Cancer by Nitric Oxide
- (2021) Inesa Navasardyan et al. Cells
- Targeting Pancreatic Cancer Cells and Stellate Cells Using Designer Nanotherapeutics in vitro
- (2020) Chandra Kumar Elechalawar et al. International Journal of Nanomedicine
- Tumor Microenvironment
- (2020) Borros Arneth Medicina-Lithuania
- Chemokines and their Receptors: Multifaceted Roles in Cancer Progression and Potential Value as Cancer Prognostic Markers
- (2020) Ha Thi Thu Do et al. Cancers
- Immunotherapy by Immune Checkpoint Inhibitors and Nuclear Medicine Imaging: Current and Future Applications
- (2020) Pierre Decazes et al. Cancers
- Evaluating the Polarization of Tumor-Associated Macrophages Into M1 and M2 Phenotypes in Human Cancer Tissue: Technicalities and Challenges in Routine Clinical Practice
- (2020) Sharmilla Devi Jayasingam et al. Frontiers in Oncology
- T follicular helper cells in germinal center B cell selection and lymphomagenesis
- (2020) Michelle A. Mintz et al. IMMUNOLOGICAL REVIEWS
- The Underappreciated Role of the Humoral Immune System and B Cells in Tumorigenesis and Cancer Therapeutics: A Review
- (2020) Victor E. Chen et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression
- (2020) Nerymar Ortiz-Otero et al. Oncotarget
- Lymphatic vessels in tumor dissemination vs. immunotherapy
- (2020) Kari Vaahtomeri et al. CANCER RESEARCH
- Cancer cells educate natural killer cells to a metastasis-promoting cell state
- (2020) Isaac S. Chan et al. JOURNAL OF CELL BIOLOGY
- The Multifaceted Roles of MSCs in the Tumor Microenvironment: Interactions With Immune Cells and Exploitation for Therapy
- (2020) Andrea Papait et al. Frontiers in Cell and Developmental Biology
- Hepatic Stellate Cells and Hepatocarcinogenesis
- (2020) Anna E. Barry et al. Frontiers in Cell and Developmental Biology
- The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity
- (2020) Laia Gorchs et al. Scientific Reports
- Tumor microenvironment and epithelial mesenchymal transition as targets to overcome tumor multidrug resistance
- (2020) Nuray Erin et al. DRUG RESISTANCE UPDATES
- Regulatory T cell targeting in cancer: Emerging strategies in immunotherapy
- (2020) Sundee Dees et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Asymptomatic hypoxia in COVID-19 is associated with poor outcome
- (2020) Philippe Brouqui et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Hypoxic exosomes orchestrate tumorigenesis: molecular mechanisms and therapeutic implications
- (2020) Reza Jafari et al. Journal of Translational Medicine
- Adipocytes promote breast tumorigenesis through TAZ-dependent secretion of Resistin
- (2020) Yuhao Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment
- (2020) Yingxia Zheng et al. Nature Communications
- Tumor microenvironment as a therapeutic target in cancer
- (2020) Yi Xiao et al. PHARMACOLOGY & THERAPEUTICS
- Impact of Epithelial–Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ
- (2019) Carina Strell et al. JNCI-Journal of the National Cancer Institute
- The Warburg effect: essential part of metabolic reprogramming and central contributor to cancer progression
- (2019) Peter Vaupel et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Targeting Tumor Microenvironment for Cancer Therapy
- (2019) Catarina Roma-Rodrigues et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- B cells in the formation of tertiary lymphoid organs in autoimmunity, transplantation and tumorigenesis
- (2019) Elisa Corsiero et al. CURRENT OPINION IN IMMUNOLOGY
- The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma
- (2019) Jacopo Baglieri et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeting hypoxia-induced carbonic anhydrase IX enhances immune checkpoint blockade locally and systemically
- (2019) Shawn C Chafe et al. Cancer Immunology Research
- Tumor-Associated Neutrophils in Cancer: Going Pro
- (2019) Wu et al. Cancers
- Role of Exosomes in Crosstalk Between Cancer-Associated Fibroblasts and Cancer Cells
- (2019) Xi Yang et al. Frontiers in Oncology
- Exosomes in esophageal cancer: A review on tumorigenesis, diagnosis and therapeutic potential
- (2019) Lin-Lin Su et al. World Journal of Clinical Cases
- Exosomes
- (2019) D. Michiel Pegtel et al. Annual Review of Biochemistry
- The Tumor Microenvironment Innately Modulates Cancer Progression
- (2019) Dominique C. Hinshaw et al. CANCER RESEARCH
- Macrophages and Metabolism in the Tumor Microenvironment
- (2019) Ilio Vitale et al. Cell Metabolism
- Exosomes and their role in tumorigenesis and anticancer drug resistance
- (2019) Neta Milman et al. DRUG RESISTANCE UPDATES
- TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis
- (2019) Yang Hao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tumor Microenvironment as A “Game Changer” in Cancer Radiotherapy
- (2019) Magdalena Jarosz-Biej et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Emerging roles of exosomal miRNAs in breast cancer drug resistance
- (2019) Hamid Najminejad et al. IUBMB LIFE
- Exosomes: Diagnostic Biomarkers and Therapeutic Delivery Vehicles for Cancer
- (2019) Liangdi Jiang et al. MOLECULAR PHARMACEUTICS
- Tumour-associated neutrophils in patients with cancer
- (2019) Merav E. Shaul et al. Nature Reviews Clinical Oncology
- Regulation of Immunity in Breast Cancer
- (2019) Chidalu Edechi et al. Cancers
- Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance
- (2019) Simona Dalin et al. CANCER RESEARCH
- Epithelial-to-mesenchymal transition and invadopodia markers in breast cancer: Lumican a key regulator
- (2019) Konstantina Karamanou et al. SEMINARS IN CANCER BIOLOGY
- NK Cell Metabolism and Tumor Microenvironment
- (2019) Iñigo Terrén et al. Frontiers in Immunology
- Cancer-associated fibroblast regulate proliferation and migration of prostate cancer cells through TGF-β signaling pathway
- (2019) Dai-Yu Sun et al. LIFE SCIENCES
- Role of hypoxia in cancer therapy by regulating the tumor microenvironment
- (2019) Xinming Jing et al. Molecular Cancer
- Tumor microenvironment components: Allies of cancer progression
- (2019) Pablo Igor Ribeiro Franco et al. PATHOLOGY RESEARCH AND PRACTICE
- Chemokines and their receptors as biomarkers in esophageal cancer
- (2019) Masakazu Goto et al. Esophagus
- Tumor Associated Neutrophils. Their Role in Tumorigenesis, Metastasis, Prognosis and Therapy
- (2019) Maria Teresa Masucci et al. Frontiers in Oncology
- CXCR4/TGF-β1 mediated hepatic stellate cells differentiation into carcinoma-associated fibroblasts and promoted liver metastasis of colon cancer
- (2019) Hao-Xiang Tan et al. CANCER BIOLOGY & THERAPY
- Mechanisms of resistance to immune checkpoint inhibitors
- (2018) Russell W Jenkins et al. BRITISH JOURNAL OF CANCER
- A Subset of Cancer-Associated Fibroblasts Determines Therapy Resistance
- (2018) Joerg Huelsken et al. CELL
- CD10 + GPR77 + Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness
- (2018) Shicheng Su et al. CELL
- Paracrine interactions of cancer-associated fibroblasts, macrophages and endothelial cells
- (2018) Roberto Ronca et al. CURRENT OPINION IN ONCOLOGY
- Microfluidic co-culture of pancreatic tumor spheroids with stellate cells as a novel 3D model for investigation of stroma-mediated cell motility and drug resistance
- (2018) Ji-Hyun Lee et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Exosomes as diagnostic biomarkers in cancer
- (2018) Jung-Hee Kim et al. Molecular & Cellular Toxicology
- A natural killer–dendritic cell axis defines checkpoint therapy–responsive tumor microenvironments
- (2018) Kevin C. Barry et al. NATURE MEDICINE
- The morphological and molecular mechanisms of epithelial/endothelial-to-mesenchymal transition and its involvement in atherosclerosis
- (2018) M. Wesseling et al. VASCULAR PHARMACOLOGY
- Mutual concessions and compromises between stromal cells and cancer cells: driving tumor development and drug resistance
- (2018) Pritish Nilendu et al. CELLULAR ONCOLOGY
- Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury
- (2018) YihHuei Uen et al. Oncotarget
- The Role of Tumor Microenvironment in Chemoresistance: 3D Extracellular Matrices as Accomplices
- (2018) Dimakatso Senthebane et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Matrix Metalloproteinase-9 (MMP-9) as a Cancer Biomarker and MMP-9 Biosensors: Recent Advances
- (2018) Hao Huang SENSORS
- Isolation of cancer-associated fibroblasts and its promotion to the progression of intrahepatic cholangiocarcinoma
- (2018) Meng Sha et al. Cancer Medicine
- T-Regulatory Cells in Health and Disease
- (2018) Eyad Elkord et al. Journal of Immunology Research
- Extracellular matrix (ECM) stiffness and degradation as cancer drivers
- (2018) Masoud Najafi et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Tumor microenvironment: Interactions and therapy
- (2018) Masoud Najafi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Immune-checkpoint inhibitors for combating T-cell dysfunction in cancer
- (2018) Ewelina Grywalska et al. OncoTargets and Therapy
- Tenascin C is a prognostic determinant and potential cancer-associated fibroblasts marker for breast ductal carcinoma
- (2017) Zhaoting Yang et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer
- (2017) E Hessmann et al. GUT
- The Role of Tumor Microenvironment in Chemoresistance: To Survive, Keep Your Enemies Closer
- (2017) Dimakatso Alice Senthebane et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
- (2017) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Transforming Growth Factor β is a Poor Prognostic Factor and Inhibits the Favorable Prognostic Value of CD8+ CTL in Human Hepatocellular Carcinoma
- (2017) Chun-yu Huang et al. JOURNAL OF IMMUNOTHERAPY
- Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4
- (2017) Christopher J Hanley et al. JNCI-Journal of the National Cancer Institute
- Biology of pancreatic stellate cells—more than just pancreatic cancer
- (2017) Pawel E. Ferdek et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- A Combination of Radiation and the Hypoxia-Activated Prodrug Evofosfamide (TH-302) is Efficacious against a Human Orthotopic Pancreatic Tumor Model
- (2017) Carla Hajj et al. Translational Oncology
- Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma
- (2017) David Kung-Chun Chiu et al. Nature Communications
- Cancer-associated fibroblasts enhance metastatic potential of lung cancer cells through IL-6/STAT3 signaling pathway
- (2017) Limin Wang et al. Oncotarget
- Targeted blockade of TGF-β and IL-6/JAK2/STAT3 pathways inhibits lung cancer growth promoted by bone marrow-derived myofibroblasts
- (2017) Jindong Shi et al. Scientific Reports
- Role of tumor microenvironment in tumorigenesis
- (2017) Maonan Wang et al. Journal of Cancer
- Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4
- (2017) Christopher J Hanley et al. JNCI-Journal of the National Cancer Institute
- Antigen-Presenting Intratumoral B Cells Affect CD4 + TIL Phenotypes in Non–Small Cell Lung Cancer Patients
- (2017) Tullia C. Bruno et al. Cancer Immunology Research
- Inhibition of CXCL12/CXCR4 axis as a potential targeted therapy of advanced gastric carcinoma
- (2017) Li-Jun Xue et al. Cancer Medicine
- Exosome-Based Cancer Therapy: Implication for Targeting Cancer Stem Cells
- (2017) Jinheng Wang et al. Frontiers in Pharmacology
- In vitro cancer cell–ECM interactions inform in vivo cancer treatment
- (2016) Andrew W. Holle et al. ADVANCED DRUG DELIVERY REVIEWS
- Intelligent Albumin-MnO2Nanoparticles as pH-/H2O2-Responsive Dissociable Nanocarriers to Modulate Tumor Hypoxia for Effective Combination Therapy
- (2016) Qian Chen et al. ADVANCED MATERIALS
- Endosialin-Expressing Pericytes Promote Metastatic Dissemination
- (2016) Carmen Viski et al. CANCER RESEARCH
- Immunosurveillance and immunotherapy of tumors by innate immune cells
- (2016) Alexandre Iannello et al. CURRENT OPINION IN IMMUNOLOGY
- Role of Matrix Metalloproteinases in Photoaging and Photocarcinogenesis
- (2016) Pavida Pittayapruek et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Dendritic Cells in the Context of Human Tumors: Biology and Experimental Tools
- (2016) Ilan Volovitz et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- The biology and function of exosomes in cancer
- (2016) Raghu Kalluri JOURNAL OF CLINICAL INVESTIGATION
- Matrix metalloproteinases (MMPs), the main extracellular matrix (ECM) enzymes in collagen degradation, as a target for anticancer drugs
- (2016) Agata Jabłońska-Trypuć et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers
- (2016) Ingrid Lua et al. JOURNAL OF HEPATOLOGY
- Tumor-Associated Macrophages and Neutrophils in Tumor Microenvironment
- (2016) Jaehong Kim et al. MEDIATORS OF INFLAMMATION
- Targeting natural killer cells in cancer immunotherapy
- (2016) Camille Guillerey et al. NATURE IMMUNOLOGY
- Dendritic Cells and Cancer Immunity
- (2016) Alycia Gardner et al. TRENDS IN IMMUNOLOGY
- B Cells Promote Pancreatic Tumorigenesis
- (2016) A. Roghanian et al. Cancer Discovery
- Cancer-associated fibroblasts promote an immunosuppressive microenvironment through the induction and accumulation of protumoral macrophages
- (2016) Hideyuki Takahashi et al. Oncotarget
- An Evaluation of the Stemness, Paracrine, and Tumorigenic Characteristics of Highly Expanded, Minimally Passaged Adipose-Derived Stem Cells
- (2016) Oula El Atat et al. PLoS One
- Tumor-associated macrophages as an emerging target against tumors: Creating a new path from bench to bedside
- (2015) Masahisa Jinushi et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- The role of exosomes and “exosomal shuttle microRNA” in tumorigenesis and drug resistance
- (2015) Lei Zhao et al. CANCER LETTERS
- Tumor microenvironment: Sanctuary of the devil
- (2015) Lanlan Hui et al. CANCER LETTERS
- Exosomes in development, metastasis and drug resistance of breast cancer
- (2015) Dan-dan Yu et al. CANCER SCIENCE
- miR-27 is associated with chemoresistance in esophageal cancer through transformation of normal fibroblasts to cancer-associated fibroblasts
- (2015) Koji Tanaka et al. CARCINOGENESIS
- Tumor-associated macrophages in cancers
- (2015) W. Hu et al. Clinical & Translational Oncology
- Regulatory B Cells: Origin, Phenotype, and Function
- (2015) Elizabeth C. Rosser et al. IMMUNITY
- Hypoxia promotes vasculogenic mimicry formation by the Twist1-Bmi1 connection in hepatocellular carcinoma
- (2015) KUN LIU et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Downregulation of Microrna-148a in Cancer-Associated Fibroblasts from Oral Cancer Promotes Cancer Cell Migration and Invasion by Targeting Wnt10b
- (2015) Anjie Min et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- The interaction of anticancer therapies with tumor-associated macrophages
- (2015) Alberto Mantovani et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis
- (2015) Miranda Y. Fong et al. NATURE CELL BIOLOGY
- Role of the Tumor Microenvironment in Breast Cancer
- (2015) Savas D. Soysal et al. PATHOBIOLOGY
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
- Different roles of myofibroblasts in the tumorigenesis of nonsmall cell lung cancer
- (2015) Jia Huang et al. TUMOR BIOLOGY
- Hypoxia-inducible factor-1α induces multidrug resistance protein in colon cancer
- (2015) Yingqian Lv et al. OncoTargets and Therapy
- Macrophages are recruited to hypoxic tumor areas and acquire a Pro-Angiogenic M2-Polarized phenotype via hypoxic cancer cell derived cytokines Oncostatin M and Eotaxin
- (2015) Chakrapani Tripathi et al. Oncotarget
- Type-2 pericytes participate in normal and tumoral angiogenesis
- (2014) Alexander Birbrair et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis
- (2014) Sonia A. Melo et al. CANCER CELL
- Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor-β (TGF-β) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein
- (2014) Steven O'Reilly et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fibroblast heterogeneity in the cancer wound
- (2014) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Absence of feedback regulation in the synthesis of COL1A1
- (2014) Kevin Dzobo et al. LIFE SCIENCES
- CD4+CD25hiCD127low Regulatory T Cells Are Increased in Oral Squamous Cell Carcinoma Patients
- (2014) Kue Peng Lim et al. PLoS One
- Prostate Tumor-Derived Exosomes Down-Regulate NKG2D Expression on Natural Killer Cells and CD8+ T Cells: Mechanism of Immune Evasion
- (2014) Marie Lundholm et al. PLoS One
- Clinical significance of lymph node metastasis in gastric cancer
- (2014) Jing-Yu Deng WORLD JOURNAL OF GASTROENTEROLOGY
- Cancer-Associated Fibroblasts as Another Polarized Cell Type of the Tumor Microenvironment
- (2014) Martin Augsten Frontiers in Oncology
- Cancer-associated fibroblasts induce epithelial–mesenchymal transition of breast cancer cells through paracrine TGF-β signalling
- (2013) Y Yu et al. BRITISH JOURNAL OF CANCER
- Chemotherapy Alters Monocyte Differentiation to Favor Generation of Cancer-Supporting M2 Macrophages in the Tumor Microenvironment
- (2013) E. M. Dijkgraaf et al. CANCER RESEARCH
- Acidity Generated by the Tumor Microenvironment Drives Local Invasion
- (2013) V. Estrella et al. CANCER RESEARCH
- Hormones of adipose tissue and their biologic role in lung cancer
- (2013) E. Ntikoudi et al. CANCER TREATMENT REVIEWS
- Bi-Directional Signaling: Extracellular Matrix and Integrin Regulation of Breast Tumor Progression
- (2013) Scott Gehler et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- Desmoplastic stroma and cholangiocarcinoma: Clinical implications and therapeutic targeting
- (2013) Alphonse E. Sirica et al. HEPATOLOGY
- Tumor associated macrophages and neutrophils in cancer
- (2013) Maria Rosaria Galdiero et al. IMMUNOBIOLOGY
- Activity of the hypoxia-activated pro-drug TH-302 in hypoxic and perivascular regions of solid tumors and its potential to enhance therapeutic effects of chemotherapy
- (2013) Jasdeep K. Saggar et al. INTERNATIONAL JOURNAL OF CANCER
- Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by InducingP4HA1, P4HA2,andPLOD2Expression in Fibroblasts
- (2013) Daniele M. Gilkes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hepatic stellate cells in liver development, regeneration, and cancer
- (2013) Chunyue Yin et al. JOURNAL OF CLINICAL INVESTIGATION
- Innate and adaptive immune cells in the tumor microenvironment
- (2013) Thomas F Gajewski et al. NATURE IMMUNOLOGY
- Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression
- (2013) G Comito et al. ONCOGENE
- TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast cancer
- (2013) S Busch et al. ONCOGENE
- Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase
- (2013) N Weizman et al. ONCOGENE
- Adipocytes: Impact on tumor growth and potential sites for therapeutic intervention
- (2013) Simona Hefetz-Sela et al. PHARMACOLOGY & THERAPEUTICS
- Caveolin-1 Expression Level in Cancer Associated Fibroblasts Predicts Outcome in Gastric Cancer
- (2013) Xianda Zhao et al. PLoS One
- Generation of Soluble NKG2D Ligands: Proteolytic Cleavage, Exosome Secretion and Functional Implications
- (2013) G. Chitadze et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Exosomes for targeted siRNA delivery across biological barriers
- (2012) Samir EL Andaloussi et al. ADVANCED DRUG DELIVERY REVIEWS
- Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis Mediated by Met Signaling Pathway
- (2012) Vesselina G. Cooke et al. CANCER CELL
- Adipose tissue and breast epithelial cells: A dangerous dynamic duo in breast cancer
- (2012) Yuan-Yuan Wang et al. CANCER LETTERS
- Epithelial-to-Mesenchymal and Endothelial-to-Mesenchymal Transition
- (2012) Jason C. Kovacic et al. CIRCULATION
- The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells
- (2012) Dennis Lindau et al. IMMUNOLOGY
- The extracellular matrix: A dynamic niche in cancer progression
- (2012) Pengfei Lu et al. JOURNAL OF CELL BIOLOGY
- Clinical and functional significance of loss of caveolin-1 expression in breast cancer-associated fibroblasts
- (2012) Samantha A Simpkins et al. JOURNAL OF PATHOLOGY
- PD1 makes waves in anticancer immunotherapy
- (2012) Alexandra Flemming NATURE REVIEWS DRUG DISCOVERY
- Silencing of miR-148a in cancer-associated fibroblasts results in WNT10B-mediated stimulation of tumor cell motility
- (2012) O Aprelikova et al. ONCOGENE
- Biomechanical Forces Shape the Tumor Microenvironment
- (2011) Adrian C. Shieh ANNALS OF BIOMEDICAL ENGINEERING
- Monoclonal antibody blockade of IL-2 receptor during lymphopenia selectively depletes regulatory T cells in mice and humans
- (2011) D. A. Mitchell et al. BLOOD
- Tumor-Associated Neutrophils: New Targets for Cancer Therapy
- (2011) A. D. Gregory et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- The expression and role of CXC chemokines in colorectal cancer
- (2011) Hannelien Verbeke et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
- (2011) T. R. Cox et al. Disease Models & Mechanisms
- Long-term in-vivo tumorigenic assessment of human culture-expanded adipose stromal/stem cells
- (2011) Zoe Marie MacIsaac et al. EXPERIMENTAL CELL RESEARCH
- The effect and clinical consequences of hypoxia on cytochrome P450, membrane carrier proteins activity and expression
- (2011) Patrick du Souich et al. Expert Opinion on Drug Metabolism & Toxicology
- Feedback regulation of the α2(1) collagen gene via the Mek-Erk signaling pathway
- (2011) Kevin Dzobo et al. IUBMB LIFE
- Mechanisms by Which the Extracellular Matrix and Integrin Signaling Act to Regulate the Switch Between Tumor Suppression and Tumor Promotion
- (2011) Patricia J. Keely JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Identification and manipulation of tumor associated macrophages in human cancers
- (2011) Moniek Heusinkveld et al. Journal of Translational Medicine
- Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320
- (2011) A. Bronisz et al. NATURE CELL BIOLOGY
- Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer
- (2011) M Musumeci et al. ONCOGENE
- Heparin-binding epidermal growth factor-like growth factor is a potent regulator of invasion activity in oral squamous cell carcinoma
- (2011) YUICHI OHNISHI et al. ONCOLOGY REPORTS
- Galectin-1 Secreted by Activated Stellate Cells in Pancreatic Ductal Adenocarcinoma Stroma Promotes Proliferation and Invasion of Pancreatic Cancer Cells
- (2011) Xiaofeng Xue et al. PANCREAS
- Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy
- (2011) David G. DeNardo et al. Cancer Discovery
- Adipose tissue derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor derived factors
- (2011) Constantin Jotzu et al. CELLULAR ONCOLOGY
- Pericytes and vessel maturation during tumor angiogenesis and metastasis
- (2010) Ahmad Raza et al. AMERICAN JOURNAL OF HEMATOLOGY
- Isolated tumor endothelial cells maintain specific character during long-term culture
- (2010) Kohei Matsuda et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hypoxia, inflammation, and the tumor microenvironment in metastatic disease
- (2010) Elizabeth C. Finger et al. CANCER AND METASTASIS REVIEWS
- Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner
- (2010) Neta Erez et al. CANCER CELL
- Hepatic stellate cell (vitamin A-storing cell) and its relative – past, present and future
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- (2010) A. Perdih et al. CURRENT MEDICINAL CHEMISTRY
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- (2008) Eric Vivier et al. NATURE IMMUNOLOGY
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