Statins Use in Alzheimer Disease: Bane or Boon from Frantic Search and Narrative Review

Deciphering the Link Between ERUPR Signaling and MicroRNA in Pathogenesis of Alzheimer’s Disease

(2022) Nusrath Yasmeen et al.   Frontiers in Aging Neuroscience

A raising dawn of pentoxifylline in management of inflammatory disorders in Covid-19

(2022) Gomaa Mostafa-Hedeab et al.   INFLAMMOPHARMACOLOGY

COVID-19 and corticosteroids: a narrative review

(2022) Gaber El-Saber Batiha et al.   INFLAMMOPHARMACOLOGY

Pentoxifylline and berberine mitigate diclofenac-induced acute nephrotoxicity in male rats via modulation of inflammation and oxidative stress

(2022) Mohammed Alorabi et al.   BIOMEDICINE & PHARMACOTHERAPY

Roxadustat for SARS-CoV-2 Infection: Old Signaling Raised New Hopes

(2022) Luay Alkazmi et al.   DRUGS IN R&D

Plasminogen activator inhibitor 1 and gestational diabetes: the causal relationship

(2022) Gaber El-Saber Batiha et al.   Diabetology & Metabolic Syndrome

Pirfenidone and post-Covid-19 pulmonary fibrosis: invoked again for realistic goals

(2022) Hayder M. Al-kuraishy et al.   INFLAMMOPHARMACOLOGY

The Potential Role of Growth Differentiation Factor 15 in COVID-19: A Corollary Subjective Effect or Not?

(2022) Ahmad O. Babalghith et al.   Diagnostics

Role of Neuropilin 1 in COVID-19 Patients with Acute Ischemic Stroke

(2022) Asma W. Al-Thomali et al.   Biomedicines

Montelukast and Acute Coronary Syndrome: The Endowed Drug

(2022) Basil Mohammed Alomair et al.   Pharmaceuticals

Microvascular Alterations in Alzheimer's Disease

(2021) Joe Steinman et al.   Frontiers in Cellular Neuroscience

The Coordination of Local Translation, Membranous Organelle Trafficking, and Synaptic Plasticity in Neurons

(2021) Dipen Rajgor et al.   Frontiers in Cell and Developmental Biology

Statin use and risk of dementia or Alzheimer’s disease: a systematic review and meta-analysis of observational studies

(2021) Elena Olmastroni et al.   European Journal of Preventive Cardiology

The efficacy of statins in the treatment of Alzheimer’s disease: a meta-analysis of randomized controlled trial

(2020) Kun Xuan et al.   NEUROLOGICAL SCIENCES

The Cognitive Effects of Statins are Modified by Age

(2020) Ahmed M. Alsehli et al.   Scientific Reports

Beneficial association of angiotensin-converting enzyme inhibitors and statins on the occurrence of possible Alzheimer’s disease after traumatic brain injury

(2020) Mingfei Li et al.   Alzheimers Research & Therapy

Late-onset vs nonmendelian early-onset Alzheimer disease

(2020) Christiane Reitz et al.   Neurology-Genetics

MicroRNAs in Alzheimer’s Disease

(2019) Mengli Wang et al.   Frontiers in Genetics

A brief history of “Alzheimer disease”

(2019) David S. Knopman et al.   NEUROLOGY

Statins and Inflammation: New Therapeutic Opportunities in Psychiatry

(2019) Sung-Wan Kim et al.   Frontiers in Psychiatry

Alzheimer’s disease clinical variants show distinct regional patterns of neurofibrillary tangle accumulation

(2019) Cathrine Petersen et al.   ACTA NEUROPATHOLOGICA

Statins exacerbate glucose intolerance and hyperglycemia in a high sucrose fed rodent model

(2019) Sriram Seshadri et al.   Scientific Reports

Association of blood lipids, atherosclerosis and statin use with dementia and cognitive impairment after stroke: a systematic review and meta-analysis

(2019) Zhirong Yang et al.   AGEING RESEARCH REVIEWS

Epidemiology of Vascular Dementia

(2019) Frank J. Wolters et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nutrients in the Prevention of Alzheimer’s Disease

(2019) Anna Laura Cremonini et al.   Oxidative Medicine and Cellular Longevity

Alterations in Gut Microbiota by Statin Therapy and Possible Intermediate Effects on Hyperglycemia and Hyperlipidemia

(2019) Jiyeon Kim et al.   Frontiers in Microbiology

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

Amyloid-β-independent regulators of tau pathology in Alzheimer disease

(2019) Rik van der Kant et al.   NATURE REVIEWS NEUROSCIENCE

Statins for neuroprotection in spontaneous intracerebral hemorrhage

(2019) Ching-Jen Chen et al.   NEUROLOGY

The effects of statins on microglial cells to protect against neurodegenerative disorders: A mechanistic review

(2019) Hossein Bagheri et al.   BIOFACTORS

Effects of Plasma Lipids and Statins on Cognitive Function

(2018) Pei-Yuan Lyu et al.   CHINESE MEDICAL JOURNAL

Systematic review of the efficacy of statins for the treatment of Alzheimer’s disease

(2018) Marta Mejías-Trueba et al.   CLINICAL MEDICINE

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

(2018) Steven E. Arnold et al.   Nature Reviews Neurology

Prevalence of preclinical Alzheimer disease

(2018) Silke Kern et al.   NEUROLOGY

Use of statins and the risk of dementia and mild cognitive impairment: A systematic review and meta-analysis

(2018) Che-Sheng Chu et al.   Scientific Reports

The role of statins in both cognitive impairment and protection against dementia: a tale of two mechanisms

(2018) Bob G. Schultz et al.   Translational Neurodegeneration

Coenzyme Q10 Decreases Amyloid Pathology and Improves Behavior in a Transgenic Mouse Model of Alzheimer's Disease

(2018) Magali Dumont et al.   JOURNAL OF ALZHEIMERS DISEASE

Statins as Neuroprotectants: A Comparative In Vitro Study of Lipophilicity, Blood-Brain-Barrier Penetration, Lowering of Brain Cholesterol, and Decrease of Neuron Cell Death

(2018) Saleta Sierra et al.   JOURNAL OF ALZHEIMERS DISEASE

Statins and Brain Health: Alzheimer’s Disease and Cerebrovascular Disease Biomarkers in Older Adults

(2018) Vijay K. Ramanan et al.   JOURNAL OF ALZHEIMERS DISEASE

Statins use and risk of dementia

(2018) Xiaoyu Zhang et al.   MEDICINE

MicroRNAs: Novel Molecular Targets and Response Modulators of Statin Therapy

(2018) Mohammad Mohajeri et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Neurovascular dysfunction in vascular dementia, Alzheimer’s and atherosclerosis

(2018) Osman Shabir et al.   BMC NEUROSCIENCE

Advances in Multi-Functional Ligands and the Need for Metal-Related Pharmacology for the Management of Alzheimer Disease

(2018) Abha Sharma et al.   Frontiers in Pharmacology

Rho GTPases as therapeutic targets in Alzheimer’s disease

(2017) Byron J. Aguilar et al.   Alzheimers Research & Therapy

Evidence for benefit of statins to modify cognitive decline and risk in Alzheimer’s disease

(2017) Nophar Geifman et al.   Alzheimers Research & Therapy

Remembering Statins: Do Statins Have Adverse Cognitive Effects?

(2016) Rafael Bitzur   DIABETES CARE

Stroke, Vascular Dementia, and Alzheimer’s Disease: Molecular Links

(2016) Murali Vijayan et al.   JOURNAL OF ALZHEIMERS DISEASE

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

(2016) Clifford R. Jack et al.   NEUROLOGY

Rosuvastatin enhances anti-inflammatory and inhibits pro-inflammatory functions in cultured microglial cells

(2016) D. Kata et al.   NEUROSCIENCE

Regulation of Cerebral Cholesterol Metabolism in Alzheimer Disease

(2016) Allison B. Reiss et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Do Statins Impair Cognition? A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2015) Brian R. Ott et al.   JOURNAL OF GENERAL INTERNAL MEDICINE

Early Statin Use and the Progression of Alzheimer Disease

(2015) Feng-Cheng Lin et al.   MEDICINE

Statins, cognition, and dementia—systematic review and methodological commentary

(2015) Melinda C. Power et al.   Nature Reviews Neurology

Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

(2014) Christiane Reitz et al.   BIOCHEMICAL PHARMACOLOGY

Fluvastatin Causes NLRP3 Inflammasome-Mediated Adipose Insulin Resistance

(2014) Brandyn D. Henriksbo et al.   DIABETES

HMGCR is a genetic modifier for risk, age of onset and MCI conversion to Alzheimer’s disease in a three cohorts study

(2014) V Leduc et al.   MOLECULAR PSYCHIATRY

Mechanism of cholesterol-assisted oligomeric channel formation by a short Alzheimer β-amyloid peptide

(2013) Coralie Di Scala et al.   JOURNAL OF NEUROCHEMISTRY

Statins, Bcl-2, and Apoptosis: Cell Death or Cell Protection?

(2013) W. Gibson Wood et al.   MOLECULAR NEUROBIOLOGY

Chronic Pravastatin but Not Atorvastatin Treatment Impairs Cognitive Function in Two Rodent Models of Learning and Memory

(2013) Sarah A. Stuart et al.   PLoS One

FDA Drug Safety Communications: A Narrative Review and Clinical Considerations for Older Adults

(2012) Zachary A. Marcum et al.   American Journal Geriatric Pharmacotherapy

Is Statin-Associated Cognitive Impairment Clinically Relevant? A Narrative Review and Clinical Recommendations

(2012) Carlos H Rojas-Fernandez et al.   ANNALS OF PHARMACOTHERAPY

Statins: Is It Really Time to Reassess Benefits and Risks?

(2012) Allison B. Goldfine   NEW ENGLAND JOURNAL OF MEDICINE

Implications of high-dose statin link with incident diabetes

(2011) Michael H. Davidson   Nature Reviews Cardiology

A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease

(2011) M. Sano et al.   NEUROLOGY

Alzheimer Disease

(2010) Rudy J. Castellani et al.   DM DISEASE-A-MONTH

Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe

(2010) H. H. Feldman et al.   NEUROLOGY

Statin Therapy Inhibits Remyelination in the Central Nervous System

(2009) Veronique E. Miron et al.   AMERICAN JOURNAL OF PATHOLOGY

Statin-Associated Adverse Cognitive Effects: Survey Results from 171 Patients

(2009) Marcella A Evans et al.   PHARMACOTHERAPY

Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study

(2008) M D M Haag et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study

(2008) C. Cramer et al.   NEUROLOGY