A Stereodivergent–Convergent Chiral Induction Mode in Atroposelective Access to Biaryls via Rhodium-Catalyzed C–H Bond Activation

Experimental and Computational Studies on the Directing Ability of Chalcogenoethers in Palladium‐Catalyzed Atroposelective C−H Olefination and Allylation

(2022) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Enantioselective Construction of Conformationally Stable C(sp2)–C(sp3) Atropisomers

(2022) Giulio Bertuzzi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt-Catalyzed Enantioselective C–H Arylation of Indoles

(2022) Nicolas Jacob et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cu(II)-Catalyzed Construction of Heterobiaryls using 1-Diazonaphthoquinones: A General Strategy for the Synthesis of QUINOX and Related P,N Ligands

(2022) Aniruddha Biswas et al.   ORGANIC LETTERS

Transition Metal-Catalyzed Biaryl Atropisomer Synthesis via a Torsional Strain Promoted Ring-Opening Reaction

(2022) Xue Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Class of Readily Tunable Planar‐Chiral Cyclopentadienyl Rhodium(III) Catalysts for Asymmetric C–H Activation

(2022) Xiaoqiang Yan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Arene Ligand as Stereocontroller for Asymmetric C−H Activation**

(2022) Hao Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Rh-Catalyzed Azide-Internal-Alkyne Cycloaddition for the Construction of Axially Chiral 1,2,3-Triazoles

(2022) Wen-Ting Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cu(I)-Catalyzed Asymmetric Arylation of Pyrroles with Diaryliodonium Salts toward the Synthesis of N–N Atropisomers

(2022) Qi Xu et al.   ORGANIC LETTERS

Pd-Catalyzed Dynamic Kinetic Asymmetric Cross-Coupling of Heterobiaryl Bromides with N-Tosylhydrazones

(2022) Shivashankar Kattela et al.   ORGANIC LETTERS

Atropisomers beyond the C–C axial chirality: Advances in catalytic asymmetric synthesis

(2022) Guang-Jian Mei et al.   Chem

Binaphthyl Scaffold: A Class of Versatile Structure in Asymmetric C–H Functionalization

(2022) Qiang Yue et al.   ACS Catalysis

Chiral Pd-Catalyzed Enantioselective Syntheses of Various N–C Axially Chiral Compounds and Their Synthetic Applications

(2021) Osamu Kitagawa   ACCOUNTS OF CHEMICAL RESEARCH

Quaternary stereocentres via catalytic enantioconvergent nucleophilic substitution reactions of tertiary alkyl halides

(2021) Zhaobin Wang et al.   Nature Chemistry

Palladium-Catalyzed Atroposelective Coupling–Cyclization of 2-Isocyanobenzamides to Construct Axially Chiral 2-Aryl- and 2,3-Diarylquinazolinones

(2021) Fan Teng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Asymmetric Synthesis of Amines via Nickel-Catalyzed Enantioconvergent Substitution Reactions

(2021) Ze-Peng Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium‐Catalyzed C‐H Activation‐Based Construction of  Axiall and Centrally Chiral Indenes through Two Discrete Insertions

(2021) Xingwei Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxygen‐linked Cyclopentadienyl Rh(III) Complexes‐Catalyzed Asymmetric C−H Arylation of Benzo[h]quinolines with 1‐Diazonaphthoquinones

(2021) Chong-Qing Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Synthesis of Silicon‐Stereogenic Dihydrodibenzosilines: Silicon Central‐to‐Axial Chirality Relay

(2021) Yonghong Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Enantioselective Ruthenium-Catalyzed C–H Alkylations by a Chiral Carboxylic Acid with Attractive Dispersive Interactions

(2021) Uttam Dhawa et al.   ORGANIC LETTERS

Atropo‐Enantioselective Oxidation‐Enabled Iridium(III)‐Catalyzed C−H Arylations with Aryl Boronic Esters

(2021) Łukasz Woźniak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nitrosobenzene‐Enabled Chiral Phosphoric Acid Catalyzed Enantioselective Construction of Atropisomeric N‐Arylbenzimidazoles

(2021) Bin Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Twofold C−H Activation‐Based Enantio‐ and Diastereoselective C−H Arylation Using Diarylacetylenes as Rare Arylating Reagents

(2021) Panjie Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Atropisomers by Transition-Metal-Catalyzed Asymmetric C–H Functionalization Reactions

(2021) Chen-Xu Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Synthesis of Protected Unnatural α-Amino Acids via Enantioconvergent Nickel-Catalyzed Cross-Coupling

(2021) Ze-Peng Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Axially Chiral Biaryls by Diels–Alder/Retro-Diels–Alder Reaction of 2-Pyrones with Alkynes

(2021) Meng-Meng Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed and Chiral Zinc Carboxylate-Assisted Allenylation of Benzamides via Kinetic Resolution

(2021) Ruxia Mao et al.   ORGANIC LETTERS

Rh(III)-Catalyzed Annulation of 2-Biphenylboronic Acid with Diverse Activated Alkenes

(2021) Bingxian Liu et al.   ORGANIC LETTERS

Enantioselective and Diastereoselective C–H Alkylation of Benzamides: Synergized Axial and Central Chirality via a Single Stereodetermining Step

(2021) Jinlei Wang et al.   ACS Catalysis

Rational design and atroposelective synthesis of N–N axially chiral compounds

(2021) Guang-Jian Mei et al.   Chem

Rhodium‐Catalyzed Atroposelective Access to Axially Chiral Olefins via C−H Bond Activation and Directing Group Migration

(2021) Ruijie Mi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Forging C−heteroatom bonds by transition-metal-catalyzed enantioselective C–H functionalization

(2021) Qi Zhang et al.   Chem

Diverse Approaches for Enantioselective C–H Functionalization Reactions Using Group 9 CpxMIII Catalysts

(2020) Tatsuhiko Yoshino et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ir-Catalyzed Atroposelective Desymmetrization of Heterobiaryls: Hydroarylation of Vinyl Ethers and Bicycloalkenes

(2020) Antonio Romero-Arenas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Synthesis of Axially Chiral Polycyclic Aromatic Hydrocarbons (PAHs) via Regioselective C–C Bond Activation of Biphenylenes

(2020) Hideaki Takano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalyst-controlled doubly enantioconvergent coupling of racemic alkyl nucleophiles and electrophiles

(2020) Haohua Huo et al.   SCIENCE

From Pd(OAc)2 to Chiral Catalysts: The Discovery and Development of Bifunctional Mono-N-Protected Amino Acid Ligands for Diverse C–H Functionalization Reactions

(2020) Qian Shao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enantioselective Twofold C‐H Annulation of Formamides and Alkynes without Built‐in Chelating Groups

(2020) Hao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective CpxRhIII–Catalyzed Carboaminations of Acrylates

(2020) Nicolai Cramer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)‐Catalyzed Atroposelective Synthesis of Biaryls by C−H Activation and Intermolecular Coupling with Sterically Hindered Alkynes

(2020) Fen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A New Class of C2‐Symmetric Chiral Cp Ligand Derived from Ferrocene Scaffold: Design, Synthesis and Application

(2020) Hao Liang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Modular Chiral N-Heterocyclic Carbene Ligands for the Nickel-Catalyzed Enantioselective C–H Functionalization of Heterocycles

(2020) Johannes Diesel et al.   CHIMIA

Divergent Synthesis of Tunable Cyclopentadienyl Ligands and Their Application in Rh-Catalyzed Enantioselective Synthesis of Isoindolinone

(2020) Wen-Jun Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Asymmetric C–H Activation of N-Methoxybenzamide with Quinone and Its Application in the Asymmetric Synthesis of a Dihydrolycoricidine Analogue

(2020) Xiaoqiang Yan et al.   ORGANIC LETTERS

Transient-axial-chirality controlled asymmetric rhodium-carbene C(sp2)-H functionalization for the synthesis of chiral fluorenes

(2020) Kuiyong Dong et al.   Nature Communications

Transition Metal‐Catalyzed Enantioselective C–H Functionalization via Chiral Transient Directing Group Strategy

(2020) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral cyclopentadienyl ligands: design, syntheses and applications in asymmetric catalysis

(2020) Nicolai Cramer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Applications of Chiral Cyclopentadienyl (Cpx) Metal Complexes in Asymmetric Catalysis

(2020) Saad Shaaban et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Designing a Planar Chiral Rhodium Indenyl Catalyst for Regio- and Enantioselective Allylic C–H Amidation

(2020) Caitlin M. B. Farr et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric CpxRh(III)-Catalyzed Acrylic Acid C–H Functionalization with Allenes Provides Chiral γ-Lactones

(2020) Shou-Guo Wang et al.   ACS Catalysis

Palladium-Catalyzed Asymmetric Allylic C–H Functionalization: Mechanism, Stereo- and Regioselectivities, and Synthetic Applications

(2020) Pu-Sheng Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cobalt(III)‐Catalyzed Enantioselective Intermolecular Carboaminations via C‒H Functionalizations

(2020) Nicolai Cramer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Bicyclo[2.2.2]octane‐Fused CpRh Complexes: Synthesis and Potential Use in Asymmetric C−H Activation

(2020) Guozhu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Functionalizations of C–H Bonds by Chiral Iridium Complexes

(2020) Łukasz Woźniak et al.   CHEMICAL REVIEWS

Pegaharmols A–B, Axially Chiral β-Carboline-quinazoline Dimers from the Roots of Peganum harmala

(2020) Sheng-Ge Li et al.   ORGANIC LETTERS

An Enantioselective CpxRh(III)-Catalyzed C-H Functionalization / Ring-Opening Route to Chiral Cyclopentenylamines

(2019) Nicolai Cramer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Cyclopentadienyl Cobalt(III) Complexes Enable Highly Enantioselective 3d-Metal-Catalyzed C–H Functionalizations

(2019) Kristers Ozols et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective C-H Activation with Earth-Abundant 3d Transition Metals

(2019) Joachim Loup et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rh(III)-Catalyzed Asymmetric Synthesis of Axially Chiral Biindolyls by Merging C–H Activation and Nucleophilic Cyclization

(2019) Miaomiao Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RhI, IrIII ,and CoIII Complexes with Atropchiral Biaryl Cyclopentadienyl Ligands: Syntheses, Structures, and Catalytic Activities

(2019) Coralie Duchemin et al.   ORGANOMETALLICS

Atroposelective Arene Formation by Carbene-Catalyzed Formal [4+2] Cycloaddition

(2019) Ke Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Annulation of ortho -Alkynylanilines: Synthesis of Axially Chiral Naphthyl-C2-indoles

(2019) Lei Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Enantioselective Oxidative [3+2] Annulation of Arenes and Azabicyclic Olefins through Twofold C−H Activation

(2019) Ruijie Mi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Control of Both Helical and Axial Stereogenic Elements though an Organocatalytic Approach

(2019) Shiqi Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Alkenyl C−H Functionalization by Cpx RhIII forms 2H -Pyrrol-2-ones through [4+1]-Annulation of Acryl Amides and Allenes

(2019) Shou-Guo Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Methylene C(sp3 )−H Amidation of 8-Alkylquinolines Using a Cp*RhIII /Chiral Carboxylic Acid System

(2019) Seiya Fukagawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cp*Co III /Chiral Carboxylic Acid‐Catalyzed Enantioselective 1,4‐Addition Reactions of Indoles to Maleimides

(2019) Takumaru Kurihara et al.   Asian Journal of Organic Chemistry

Rhodium(III)-Catalyzed Enantio- and Diastereoselective C−H Cyclopropylation of N-Phenoxylsulfonamides: Combined Experimental and Computational Studies

(2019) Guangfan Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Planar-Chiral Rhodium(III) Catalyst with a Sterically Demanding Cyclopentadienyl Ligand and Its Application in the Enantioselective Synthesis of Dihydroisoquinolones

(2018) Evgeniya A. Trifonova et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Syntheses, Structures, and Reactions of Cyclometalated Rhodium, Iridium, and Ruthenium Complexes of N-Methoxy-4-nitrobenzamide

(2018) Tao Zhou et al.   ORGANOMETALLICS

Tailored trisubstituted chiral CpxRhIII catalysts for kinetic resolutions of phosphinic amides

(2018) Y. Sun et al.   Chemical Science

Access to P - and Axially Chiral Biaryl Phosphine Oxides by Enantioselective Cpx IrIII -Catalyzed C−H Arylations

(2018) Yun-Suk Jang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rh(III)-Catalyzed C–H Activation of Boronic Acid with Aryl Azide

(2018) Shiyang Xu et al.   ORGANIC LETTERS

Enantioselective Cobalt(III)-Catalyzed C−H Activation Enabled by Chiral Carboxylic Acid Cooperation

(2018) Fabio Pesciaioli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Syntheses of Furan Atropisomers by an Oxidative Central-to-Axial Chirality Conversion Strategy

(2017) Vivek S. Raut et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Asymmetric Reductive Cross-Coupling To Access 1,1-Diarylalkanes

(2017) Kelsey E. Poremba et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

P(O)R2-Directed Enantioselective C–H Olefination toward Chiral Atropoisomeric Phosphine–Olefin Compounds

(2017) Shi-Xia Li et al.   ORGANIC LETTERS

Enantioselective C–H Annulation of Indoles with Diazo Compounds through a Chiral Rh(III) Catalyst

(2017) Xiaohong Chen et al.   ACS Catalysis

Engaging Radicals in Transition Metal-Catalyzed Cross-Coupling with Alkyl Electrophiles: Recent Advances

(2017) Atsushi Kaga et al.   ACS Catalysis

Rhodium(III)-Catalyzed Enantiotopic C−H Activation Enables Access to P -Chiral Cyclic Phosphinamides

(2016) Yang Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes

(2016) Jun Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Oxidative Annulation of (2-Arylphenyl)boronic Acids with Alkynes: Selective Synthesis of Phenanthrene Derivatives

(2016) Tetsuya Satoh et al.   SYNLETT

Iridium-Catalyzed Diastereo-, Enantio-, and Regioselective Allylic Alkylation with Prochiral Enolates

(2016) J. Caleb Hethcox et al.   ACS Catalysis

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C–H Functionalizations

(2015) Baihua Ye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chiral Cyclopentadienyl Iridium(III) Complexes Promote Enantioselective Cycloisomerizations Giving Fused Cyclopropanes

(2015) Michael Dieckmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Axially Chiral Isoquinolones: Nickel-Catalyzed Denitrogenative Transannulation

(2015) Zhi-Jia Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A [4+1] Cyclative Capture Approach to 3H-Indole-N-oxides at Room Temperature by Rhodium(III)-Catalyzed CH Activation

(2015) Yaxi Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Atropisomeric Vinyl Arene Compounds by Palladium Catalysis: A Carbene Strategy

(2015) Jia Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Palladium-catalysed norbornene-mediated C–H functionalization of arenes

(2015) Juntao Ye et al.   Nature Chemistry

Copper-catalyzed condensation of imines and α-diazo-β-dicarbonyl compounds: modular and regiocontrolled synthesis of multisubstituted pyrroles

(2015) Wei Wen Tan et al.   Chemical Science

A C–H bond activation-based catalytic approach to tetrasubstituted chiral allenes

(2015) Shangze Wu et al.   Nature Communications

A DFT Study on Rh-Catalyzed Asymmetric Dearomatization of 2-Naphthols Initiated with C–H Activation: A Refined Reaction Mechanism and Origins of Multiple Selectivity

(2015) Chao Zheng et al.   ACS Catalysis

Organocatalytic Atroposelective Aldol Condensation: Synthesis of Axially Chiral Biaryls by Arene Formation

(2014) Achim Link et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Isoindolones by Chiral Cyclopentadienyl-Rhodium(III)-Catalyzed CH Functionalizations

(2014) Baihua Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Tunable Class of Chiral Cp Ligands for Enantioselective Rhodium(III)-Catalyzed C–H Allylations of Benzamides

(2013) Baihua Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(III)-Catalyzed Synthesis of Multisubstituted Isoquinoline and Pyridine N-Oxides from Oximes and Diazo Compounds

(2013) Zhuangzhi Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrazone as the Directing Group for Ir-Catalyzed Arene Diborylations and Sequential Functionalizations

(2012) Abel Ros et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh-Catalyzed Intermolecular Carbenoid Functionalization of Aromatic C–H Bonds by α-Diazomalonates

(2012) Wai-Wing Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biotinylated Rh(III) Complexes in Engineered Streptavidin for Accelerated Asymmetric C-H Activation

(2012) T. K. Hyster et al.   SCIENCE

Chiral Cyclopentadienyl Ligands as Stereocontrolling Element in Asymmetric C-H Functionalization

(2012) B. Ye et al.   SCIENCE

Coupling of N-Tosylhydrazones with Terminal Alkynes Catalyzed by Copper(I): Synthesis of Trisubstituted Allenes

(2010) Qing Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

Enantioselective Synthesis of Biphenols from 1,4-Diketones by Traceless Central-to-Axial Chirality Exchange

(2010) Fenghai Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total synthesis of chiral biaryl natural products by asymmetric biaryl coupling

(2009) Marisa C. Kozlowski et al.   CHEMICAL SOCIETY REVIEWS

Merging of E2 and E1cb Reaction Mechanisms: A Combined Theoretical and Experimental Study

(2009) Edoardo Mosconi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Iridium-Catalyzed Enantioselective Formal [4+2] Cycloaddition of Biphenylene and Alkynes for the Construction of Axial Chirality

(2008) Takanori Shibata et al.   SYNLETT