Enantioselective Rh-Catalyzed Azide-Internal-Alkyne Cycloaddition for the Construction of Axially Chiral 1,2,3-Triazoles

Organocatalytic cycloaddition of alkynylindoles with azonaphthalenes for atroposelective construction of indole-based biaryls

(2022) Hui Yang et al.   Nature Communications

Chiral Pd-Catalyzed Enantioselective Syntheses of Various N–C Axially Chiral Compounds and Their Synthetic Applications

(2021) Osamu Kitagawa   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of Axially Chiral 2,2′-Bisphosphobiarenes via a Nickel-Catalyzed Asymmetric Ullmann Coupling: General Access to Privileged Chiral Ligands without Optical Resolution

(2021) Ziqing Zuo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium‐Catalyzed C‐H Activation‐Based Construction of  Axiall and Centrally Chiral Indenes through Two Discrete Insertions

(2021) Xingwei Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Enantioselective Nickel-Catalyzed Alkyne–Azide Cycloaddition by Dynamic Kinetic Resolution

(2021) En-Chih Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nitrene-mediated intermolecular N–N coupling for efficient synthesis of hydrazides

(2021) Hao Wang et al.   Nature Chemistry

Chiral Phosphoric Acid-Catalyzed Remote Control of Axial Chirality at Boron–Carbon Bond

(2021) Junxian Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Axially Chiral Biaryls by Diels–Alder/Retro-Diels–Alder Reaction of 2-Pyrones with Alkynes

(2021) Meng-Meng Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Construction of Chiroptical Boron-Stereogenic Compounds

(2021) Bing Zu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Enantioselective Arylative Activation of Aromatic C–O Bond

(2021) Jintong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral-Phosphoric-Acid-Catalyzed Atroposelective C-H Amination of Arenes

(2020) Bin Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Axially Chiral Biaryl-2-amines by PdII -Catalyzed Free-Amine-Directed Atroposelective C−H Olefination

(2020) Bei-Bei Zhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intermolecular Palladium(0)-Catalyzed Atropo-enantioselective C–H Arylation of Heteroarenes

(2020) Qui-Hien Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Layered Chirality Relay Model in Rh(I)-Mediated Enantioselective C–Si Bond Activation: A Theoretical Study

(2020) Shihan Liu et al.   ORGANIC LETTERS

Enantioselective Cu(I)-Catalyzed Cycloaddition of Prochiral Diazides with Terminal or 1-Iodoalkynes

(2020) Cai Wang et al.   ORGANIC LETTERS

Catalytic Asymmetric Construction of Axially Chiral Indole‐Based Frameworks: An Emerging Area

(2020) Tian-Zhen Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Michael Reaction Inspired Atroposelective Construction of Axially Chiral Biaryls

(2020) Shengyi Yan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition Metal‐Catalyzed Enantioselective C–H Functionalization via Chiral Transient Directing Group Strategy

(2020) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DFT-Guided Phosphoric-Acid-Catalyzed Atroposelective Arene Functionalization of Nitrosonaphthalene

(2020) Wei-Yi Ding et al.   Chem

Design and Atroposelective Construction of IAN analogues by Organocatalytic Asymmetric Heteroannulation of Alkynes

(2020) Lei Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Atroposelective Oxidative C–H/C–H Cross-Coupling Reaction of 1-Aryl Isoquinoline Derivatives with Electron-Rich Heteroarenes

(2020) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective CuAAC of Functional Tertiary Alcohols Featuring an Ethynyl Group and Their Kinetic Resolution

(2020) Kui Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Atropisomers Featuring Pentatomic Heteroaromatics by Pd-Catalyzed C–H Alkynylation

(2019) Shuo Zhang et al.   ACS Catalysis

Enantioselective Copper Catalyzed Alkyne–Azide Cycloaddition by Dynamic Kinetic Resolution

(2019) En-Chih Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Kinetic Resolution by Enantioselective Aromatization: Conversion of Racemic Intermediates of the Barton-Zard Reaction into Enantioenriched 3-Arylpyrroles

(2019) Sheng-Cai Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetic Resolution of Cyclic Secondary Azides, Using an Enantioselective Copper-Catalyzed Azide–Alkyne Cycloaddition

(2019) Juliana R. Alexander et al.   ORGANIC LETTERS

Asymmetric Construction of Axially Chiral 2-Arylpyrroles via Chirality Transfer of Atropisomeric Alkenes

(2019) Bin Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Chiral Aldehyde Catalysts by Pd-Catalyzed Atroposelective C−H Naphthylation

(2019) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rh(III)-Catalyzed Asymmetric Synthesis of Axially Chiral Biindolyls by Merging C–H Activation and Nucleophilic Cyclization

(2019) Miaomiao Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rational design, enantioselective synthesis and catalytic applications of axially chiral EBINOLs

(2019) Yong-Bin Wang et al.   Nature Catalysis

Induction of Planar Chirality Using Asymmetric Click Chemistry by a Novel Desymmetrisation of 1,3-Bisalkynyl Ferrocenes

(2019) Adam J. Wright et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Asymmetric Annulation of ortho -Alkynylanilines: Synthesis of Axially Chiral Naphthyl-C2-indoles

(2019) Lei Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Strategy for Synthesizing Axially Chiral Naphthyl-Indoles: Catalytic Asymmetric Addition Reactions of Racemic Substrates

(2019) Fei Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereo- and Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade

(2019) Shenci Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Coetaneous catalytic kinetic resolution of alkynes and azides through asymmetric triazole formation

(2019) William D. G. Brittain et al.   Scientific Reports

Organocatalytic Asymmetric Synthesis of Indole-Based Chiral Heterocycles: Strategies, Reactions, and Outreach

(2019) Yu-Chen Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

(2018) Yong-Bin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chiral Bisdiphenylphosphine Dioxides Bearing a Bis(triazolyl) Backbone as Promising Lewis Bases for Asymmetric Organocatalysis

(2018) Nicolas Sevrain et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Enantioselective Construction of Axially Chiral Sulfone-Containing Styrenes

(2018) Shiqi Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Atropenantioselective Heteroannulation between Isocyanoacetates and Alkynyl Ketones: Synthesis of Enantioenriched Axially Chiral 3-Arylpyrroles

(2018) Sheng-Cai Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and Catalytic Asymmetric Construction of Axially Chiral 3,3′-Bisindole Skeletons

(2018) Chun Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Construction of Vicinal Diaxial Styrenes and Multiaxis System via Organocatalysis

(2018) Yu Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Syntheses of Furan Atropisomers by an Oxidative Central-to-Axial Chirality Conversion Strategy

(2017) Vivek S. Raut et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dicopper Cu(I)Cu(I) and Cu(I)Cu(II) Complexes in Copper-Catalyzed Azide–Alkyne Cycloaddition

(2017) Micah S. Ziegler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic asymmetric arylation of indoles enabled by azo groups

(2017) Liang-Wen Qi et al.   Nature Chemistry

Rhodium-Catalyzed Azide–Alkyne Cycloaddition of Internal Ynamides: Regioselective Assembly of 5-Amino-Triazoles under Mild Conditions

(2017) Yun Liao et al.   ACS Catalysis

Enantioselective Synthesis of Indole-Based Biaryl Atropisomers via Palladium-Catalyzed Dynamic Kinetic Intramolecular C–H Cyclization

(2017) Congfa He et al.   ACS Catalysis

5,5′-Bistriazoles as axially chiral, multidentate ligands: synthesis, configurational stability and catalytic application of their scandium(iii) complexes

(2017) Pablo Etayo et al.   Catalysis Science & Technology

Design and Enantioselective Construction of Axially Chiral Naphthyl-Indole Skeletons

(2016) Hong-Hao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective synthesis of multisubstituted 1,2,3-triazoles: moving beyond the copper-catalyzed azide–alkyne cycloaddition

(2016) Fang Wei et al.   CHEMICAL COMMUNICATIONS

Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reaction: Scope, Mechanism, and Applications

(2016) Johan R. Johansson et al.   CHEMICAL REVIEWS

Cu-Catalyzed Click Reaction in Carbohydrate Chemistry

(2016) Vinod K. Tiwari et al.   CHEMICAL REVIEWS

The Bull–James assembly as a chiral auxiliary and shift reagent in kinetic resolution of alkyne amines by the CuAAC reaction

(2016) William D. G. Brittain et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Copper-Catalyzed Azide–Alkyne Cycloadditions

(2016) William D. G. Brittain et al.   ACS Catalysis

Kinetic resolution of alkyne-substituted quaternary oxindoles via copper catalysed azide–alkyne cycloadditions

(2015) William D. G. Brittain et al.   CHEMICAL COMMUNICATIONS

Mechanistic Insights into Copper-Catalyzed Azide–Alkyne Cycloaddition (CuAAC): Observation of Asymmetric Amplification

(2015) Yasuhiro Uozumi et al.   SYNLETT

Enantioselective Copper-Catalyzed Azide-Alkyne Click Cycloaddition to Desymmetrization of Maleimide-Based Bis(alkynes)

(2014) Tao Song et al.   CHEMISTRY-A EUROPEAN JOURNAL

Theoretical Studies on the Regioselectivity of Iridium-Catalyzed 1,3-Dipolar Azide–Alkyne Cycloaddition Reactions

(2014) Qiong Luo et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioposition-Selective Copper-Catalyzed Azide–Alkyne Cycloaddition for Construction of Chiral Biaryl Derivatives

(2014) Takao Osako et al.   ORGANIC LETTERS

Asymmetric Copper(I)-Catalyzed Azide–Alkyne Cycloaddition to Quaternary Oxindoles

(2013) Feng Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Evidence of a Dinuclear Copper Intermediate in Cu(I)-Catalyzed Azide-Alkyne Cycloadditions

(2013) B. T. Worrell et al.   SCIENCE

An Investigation of the Asymmetric Huisgen ‘Click’ Reaction

(2013) G. Stephenson et al.   SYNLETT

Reliable and Efficient Procedures for the Conjugation of Biomolecules through Huisgen Azide-Alkyne Cycloadditions

(2011) Enrique Lallana et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Click Chemistry: 1,2,3-Triazoles as Pharmacophores

(2011) Sandip G. Agalave et al.   Chemistry-An Asian Journal

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

Click chemistry: function follows form

(2010) M. G. Finn et al.   CHEMICAL SOCIETY REVIEWS

Copper-catalyzed azide–alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(i) acetylides

(2010) Jason E. Hein et al.   CHEMICAL SOCIETY REVIEWS

Click polymerization

(2010) Anjun Qin et al.   CHEMICAL SOCIETY REVIEWS

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total synthesis of chiral biaryl natural products by asymmetric biaryl coupling

(2009) Marisa C. Kozlowski et al.   CHEMICAL SOCIETY REVIEWS