Rhodium(III)-Catalyzed Enantio- and Diastereoselective C−H Cyclopropylation of N-Phenoxylsulfonamides: Combined Experimental and Computational Studies

An Enantioselective CpxRh(III)-Catalyzed C-H Functionalization / Ring-Opening Route to Chiral Cyclopentenylamines

(2019) Nicolai Cramer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cobalt-Catalyzed Regio- and Diastereoselective Formal [3 + 2] Cycloaddition between Cyclopropanols and Allenes

(2019) Junfeng Yang et al.   ACS Catalysis

A Tandem Iridium-Catalyzed “Chain-Walking”/Cope Rearrangement Sequence

(2019) Heiko Sommer et al.   ACS Catalysis

Synthesis of 1,2-divinylcyclopropanes by metal-catalyzed cyclopropanation of 1,3-dienes with cyclopropenes as vinyl carbene precursors

(2019) Jesús González et al.   Beilstein Journal of Organic Chemistry

[(NHC)NiII H]-Catalyzed Cross-Hydroalkenylation of Cyclopropenes with Alkynes: Cyclopentadiene Synthesis by [(NHC)NiII ]-Assisted C−C Rearrangement

(2019) Jian-Qiang Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Beyond the Second Coordination Sphere: Engineering Dirhodium Artificial Metalloenzymes To Enable Protein Control of Transition Metal Catalysis

(2019) Jared C. Lewis   ACCOUNTS OF CHEMICAL RESEARCH

Rh(III)-Catalyzed C–H Activation-Initiated Directed Cyclopropanation of Allylic Alcohols

(2019) Erik J. T. Phipps et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt-Catalyzed Diastereo- and Enantioselective Hydroalkenylation of Cyclopropenes with Alkenylboronic Acids

(2019) Haiyan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rh(III)-Catalyzed Asymmetric Synthesis of Axially Chiral Biindolyls by Merging C–H Activation and Nucleophilic Cyclization

(2019) Miaomiao Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multicomponent Cyclopropane Synthesis Enabled by Cu-Catalyzed Cyclopropene Carbometalation with Organoboron Reagent: Enantioselective Modular Access to Polysubstituted 2-Arylcyclopropylamines

(2019) Zhanyu Li et al.   ORGANIC LETTERS

Catalytic Enantioselective Cloke-Wilson Rearrangement

(2018) Alesandere Ortega et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Arylation of Cyclopropenes Based on Asymmetric Direct Functionalization of Three-Membered Carbocycles

(2018) Longyang Dian et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Catalytic Preparation of Polysubstituted Cyclopropanol and Cyclopropylamine Derivatives

(2018) Marwan Simaan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Planar-Chiral Rhodium(III) Catalyst with a Sterically Demanding Cyclopentadienyl Ligand and Its Application in the Enantioselective Synthesis of Dihydroisoquinolones

(2018) Evgeniya A. Trifonova et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Synthesis of Arylated Furans by a Sequential Rh-Catalyzed Arylation and Cycloisomerization of Cyclopropenes

(2018) Xiaoming Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Formation and Cleavage of C–C Bonds by Enzymatic Oxidation–Reduction Reactions

(2018) F. Peter Guengerich et al.   CHEMICAL REVIEWS

Modular Access to Azepines by Directed Carbonylative C–C Bond Activation of Aminocyclopropanes

(2018) Gang-Wei Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric C(sp)–H Addition of Terminal Alkynes to Cyclopropenes by a Chiral Gadolinium Catalyst

(2018) Huai-Long Teng et al.   ACS Catalysis

Rh(III)-Catalyzed Mild Coupling of Nitrones and Azomethine Imines with Alkylidenecyclopropanes via C–H Activation: Facile Access to Bridged Cycles

(2018) Dachang Bai et al.   ACS Catalysis

Stereoselective Enzymatic Synthesis of Heteroatom-Substituted Cyclopropanes

(2018) Oliver F. Brandenberg et al.   ACS Catalysis

Asymmetric Preparation of Polysubstituted Cyclopropanes Based on Direct Functionalization of Achiral Three-Membered Carbocycles

(2018) Longyang Dian et al.   CHEMICAL REVIEWS

Rh(I)-Catalyzed Carbonylative [3+1] Construction of Cyclobutenones via C-C σ-Bond Activation of Cyclopropenes

(2018) Wen-Bin Xu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Stereodivergent Rhodium(III)-Catalyzed cis-Cyclopropanation Enabled by Multivariate Optimization

(2018) Tiffany Piou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Enantioselective Coupling of Indoles and 7-Azabenzonorbornadienes by C−H Activation/Desymmetrization

(2018) Xifa Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Use of Cyclopropane as C1 Synthetic Unit by Directed Retro-Cyclopropanation with Ethylene Release

(2018) Sobi Asako et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alternate Heme Ligation Steers Activity and Selectivity in Engineered Cytochrome P450-Catalyzed Carbene-Transfer Reactions

(2018) Kai Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium(0)-Catalyzed Intramolecular Cascade Cyclization of Methylenecyclopropanes

(2018) Wei Fang et al.   ORGANIC LETTERS

Construction of Substituted 2-Aminophenols via Formal [3 + 3] Cycloaddition of Alkyl 2-Aroyl-1-chlorocyclopropanecarboxylate with in Situ Generated Enamines

(2018) Sen Yang et al.   ORGANIC LETTERS

Copper-Catalyzed Asymmetric Aminocyanation of Arylcyclopropanes for Synthesis of γ-Amino Nitriles

(2018) Shengbiao Yang et al.   ACS Catalysis

Umpolung α-Silylation of Cyclopropyl Acetates via Low-Temperature Catalytic C–C Activation

(2018) Thirupataiah Avullala et al.   ACS Catalysis

Origin of high stereocontrol in olefin cyclopropanation catalyzed by an engineered carbene transferase

(2018) Antonio Tinoco et al.   ACS Catalysis

Diastereodivergent Asymmetric Carboamination/Annulation of Cyclopropenes with Aminoalkenes by Chiral Lanthanum Catalysts

(2017) Huai-Long Teng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Nitrone Synthesis via Ligand-Enabled Copper-Catalyzed Cope-Type Hydroamination of Cyclopropene with Oxime

(2017) Zhanyu Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(III)-Catalyzed Redox-Neutral Unsymmetrical C–H Alkylation and Amidation Reactions of N-Phenoxyacetamides

(2017) Yunxiang Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cp*Rh(III)/Bicyclic Olefin Cocatalyzed C–H Bond Amidation by Intramolecular Amide Transfer

(2017) Xiaoming Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Heptamethylindenyl (Ind*) enables diastereoselective benzamidation of cyclopropenes via Rh(iii)-catalyzed C–H activation

(2017) Natthawat Semakul et al.   Chemical Science

Plausible Rh(V) Intermediates in Catalytic C–H Activation Reactions

(2017) Suhelen Vásquez-Céspedes et al.   ACS Catalysis

Synthesis of Chiral Aminocyclopropanes by Rare-Earth-Metal-Catalyzed Cyclopropene Hydroamination

(2016) Huai-Long Teng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper mediated carbometalation reactions

(2016) D. S. Müller et al.   CHEMICAL SOCIETY REVIEWS

Transition metal-catalysed couplings between arenes and strained or reactive rings: combination of C–H activation and ring scission

(2016) Fen Wang et al.   CHEMICAL SOCIETY REVIEWS

Mild metal-catalyzed C–H activation: examples and concepts

(2016) T. Gensch et al.   CHEMICAL SOCIETY REVIEWS

The “Cyclopropyl Fragment” is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules

(2016) Tanaji T. Talele   JOURNAL OF MEDICINAL CHEMISTRY

Computational Exploration of RhIII/RhV and RhIII/RhI Catalysis in Rhodium(III)-Catalyzed C–H Activation Reactions of N-Phenoxyacetamides with Alkynes

(2016) Yun-Fang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Catalysis Powered by Chiral Cyclopentadienyl Ligands

(2016) Christopher G. Newton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes

(2016) Jun Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Progresses towards the Strengthening of Cyclopropene Chemistry

(2016) Rubén Vicente   SYNTHESIS-STUTTGART

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C–H Functionalizations

(2015) Baihua Ye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Intramolecular Cyclopropanation and C–H Insertion Reactions with Metal Carbenoids Generated from Cyclopropenes

(2015) Alexis Archambeau et al.   ACCOUNTS OF CHEMICAL RESEARCH

Catalytic C–C Bond Activations via Oxidative Addition to Transition Metals

(2015) Laetitia Souillart et al.   CHEMICAL REVIEWS

Asymmetric Copper-Catalyzed Carbozincation of Cyclopropenes en Route to the Formation of Diastereo- and Enantiomerically Enriched Polysubstituted Cyclopropanes

(2015) Daniel S. Müller et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(III)-Catalyzed C–H Alkylation of Arenes Using Alkylboron Reagents

(2015) He Wang et al.   ORGANIC LETTERS

Rhodium(III)-Catalyzed Transannulation of Cyclopropenes withN-Phenoxyacetamides through CH Activation

(2014) Hang Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Axial Chirality by Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes

(2014) Jun Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rh(III)-Catalyzed Cyclopropanation Initiated by C–H Activation: Ligand Development Enables a Diastereoselective [2 + 1] Annulation of N-Enoxyphthalimides and Alkenes

(2014) Tiffany Piou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Diastereo- and Enantioselective Desymmetrization of Cyclopropenes: Synthesis of Cyclopropylboronates

(2014) Alejandro Parra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Cyclopropanation Reactions

(2014) Renato Dalpozzo et al.   SYNTHESIS-STUTTGART

Copper(i)-catalyzed enantioselective hydroboration of cyclopropenes: facile synthesis of optically active cyclopropylboronates

(2014) Bing Tian et al.   Organic Chemistry Frontiers

Direct CH Amination of Arenes with Alkyl Azides under Rhodium Catalysis

(2013) Kwangmin Shin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Cp-Rhodium(III)-Catalyzed Asymmetric Hydroarylations of 1,1-Disubstituted Alkenes

(2013) Baihua Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic C–C Bond-Forming Multi-Component Cascade or Domino Reactions: Pushing the Boundaries of Complexity in Asymmetric Organocatalysis

(2013) Chandra M. R. Volla et al.   CHEMICAL REVIEWS

A Tunable Class of Chiral Cp Ligands for Enantioselective Rhodium(III)-Catalyzed C–H Allylations of Benzamides

(2013) Baihua Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed C-H Activation Mediated Synthesis of Isoquinolones from Amides and Cyclopropenes

(2013) Tomislav Rovis et al.   SYNLETT

Recent advances in the total synthesis of cyclopropane-containing natural products

(2012) David Y.-K. Chen et al.   CHEMICAL SOCIETY REVIEWS

Biotinylated Rh(III) Complexes in Engineered Streptavidin for Accelerated Asymmetric C-H Activation

(2012) T. K. Hyster et al.   SCIENCE

Chiral Cyclopentadienyl Ligands as Stereocontrolling Element in Asymmetric C-H Functionalization

(2012) B. Ye et al.   SCIENCE

Designing N-Heterocyclic Carbenes: Simultaneous Enhancement of Reactivity and Enantioselectivity in the Asymmetric Hydroacylation of Cyclopropenes

(2011) Fan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent developments of cyclopropene chemistry

(2011) Zhi-Bin Zhu et al.   CHEMICAL SOCIETY REVIEWS

Computational Elucidation of the Internal Oxidant-Controlled Reaction Pathways in Rh(III)-Catalyzed Aromatic C–H Functionalization

(2011) Liang Xu et al.   JOURNAL OF ORGANIC CHEMISTRY

Arylcyclopropanes: Properties, Synthesis and Use in Medicinal Chemistry

(2010) Alexandre Gagnon et al.   ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL

Catalytic Carbene Insertion into C−H Bonds

(2009) Michael P. Doyle et al.   CHEMICAL REVIEWS

Challenges in Modern Drug Discovery: A Case Study of Boceprevir, an HCV Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

(2008) F. George Njoroge et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Simmons–Smith Reaction of Allylic Alcohols with Al Lewis Acid/N Lewis Base Bifunctional Al(Salalen) Catalyst

(2008) Hiroaki Shitama et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION