Rhodium(III)‐Catalyzed Atroposelective Synthesis of Biaryls by C−H Activation and Intermolecular Coupling with Sterically Hindered Alkynes

Synthesis of Axially Chiral Biaryl-2-amines by PdII -Catalyzed Free-Amine-Directed Atroposelective C−H Olefination

(2020) Bei-Bei Zhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intermolecular Palladium(0)-Catalyzed Atropo-enantioselective C–H Arylation of Heteroarenes

(2020) Qui-Hien Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Axially Chiral Biaryl Monophosphine Oxides Enabled by Palladium/WJ-Phos-Catalyzed Asymmetric Suzuki–Miyaura Cross-coupling

(2020) Wangqin Ji et al.   ACS Catalysis

Enantioselective Synthesis of Atropisomers Featuring Pentatomic Heteroaromatics by Pd-Catalyzed C–H Alkynylation

(2019) Shuo Zhang et al.   ACS Catalysis

Enantioselective Synthesis of Biaryl Atropisomers via Pd-Catalyzed C-H Olefination using Chiral Spiro Phosphoric Acid Ligands

(2019) Jun Luo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of C-N Axially Chiral N-Aryloxindoles by Asymmetric Rhodium-Catalyzed Dual C-H Activation

(2019) Honghe Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cu-Complex Catalyzed Asymmetric Aerobic Oxidative Cross Coupling of 2-Naphthols: Enantioselective Synthesis of C1-symmetric BINOLs Bearing 3,3′-Disubstituents

(2019) Jin-Miao Tian et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Barton–Zard Reaction To Access 3-Pyrrole-Containing Axially Chiral Skeletons

(2019) Xiao-Long He et al.   ACS Catalysis

Enantioselective Carbon-Carbon Bond Cleavage for Biaryl Atropisomers Synthesis

(2019) Ruixian Deng et al.   Chem

Synthesis of Chiral Aldehyde Catalysts by Pd-Catalyzed Atroposelective C−H Naphthylation

(2019) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Atroposelective C–H Arylation: Efficient Synthesis of Axially Chiral Heterobiaryls

(2019) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(III)-Catalyzed Asymmetric Synthesis of Axially Chiral Biindolyls by Merging C–H Activation and Nucleophilic Cyclization

(2019) Miaomiao Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium-Catalyzed Enantioselective C–H Functionalization: A Practical Access to Optically Active Indoline Derivatives

(2019) Zhong-Yuan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Bulky Chiral N-Heterocyclic Carbene Palladium Catalyst Enables Highly Enantioselective Suzuki–Miyaura Cross-Coupling Reactions for the Synthesis of Biaryl Atropisomers

(2019) Di Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Enantio- and Diastereoselective C−H Cyclopropylation of N-Phenoxylsulfonamides: Combined Experimental and Computational Studies

(2019) Guangfan Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium(II)-Catalyzed Asymmetric Inert C−H Bond Activation Assisted by a Chiral Transient Directing Group

(2019) Guozhu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Enantioselective Cacchi Reaction: Asymmetric Synthesis of Axially Chiral 2,3-Disubstituted Indoles

(2019) Yu-Ping He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

(2018) Yong-Bin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Axially Chiral Dibenzazepinones via a Pd(0)-Catalyzed Atropo-enantioselective C-H Arylation

(2018) Nicolai Cramer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Scalable, Stereocontrolled Formal Syntheses of (+)-Isoschizandrin and (+)-Steganone: Development and Applications of Palladium(II)-Catalyzed Atroposelective C−H Alkynylation

(2018) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Planar-Chiral Rhodium(III) Catalyst with a Sterically Demanding Cyclopentadienyl Ligand and Its Application in the Enantioselective Synthesis of Dihydroisoquinolones

(2018) Evgeniya A. Trifonova et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Solvent-Dependent Asymmetric Synthesis of Alkynyl and Monofluoroalkenyl Isoindolinones by CpRhIII -Catalyzed C−H Activation

(2018) Teng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two Stereoinduction Events in One C−H Activation Step: A Route towards Terphenyl Ligands with Two Atropisomeric Axes

(2018) Quentin Dherbassy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective arene formation

(2018) Achim Link et al.   CHEMICAL SOCIETY REVIEWS

Catalyst-Controlled Stereoselective Synthesis of Atropisomers

(2018) Bouthayna Zilate et al.   ACS Catalysis

C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors

(2018) Herbert Waldmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Access to P - and Axially Chiral Biaryl Phosphine Oxides by Enantioselective Cpx IrIII -Catalyzed C−H Arylations

(2018) Yun-Suk Jang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic Kinetic Asymmetric Heck Reaction for the Simultaneous Generation of Central and Axial Chirality

(2018) José A. Carmona et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki-Miyaura and Negishi Cross-Coupling Reactions for Tetra-ortho-Substituted Biaryl Synthesis

(2018) Nitinchandra Dahyabhai Patel et al.   ACS Catalysis

Catalytic Atropenantioselective Heteroannulation between Isocyanoacetates and Alkynyl Ketones: Synthesis of Enantioenriched Axially Chiral 3-Arylpyrroles

(2018) Sheng-Cai Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-Catalyzed Atroposelective C−H Allylation through β-O Elimination: Diverse Synthesis of Axially Chiral Biaryls

(2018) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Formal C(sp3 )−H Bond Activation in the Synthesis of Bioactive Spiropyrazolone Derivatives

(2018) Houhua Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

P(O)R2-Directed Enantioselective C–H Olefination toward Chiral Atropoisomeric Phosphine–Olefin Compounds

(2017) Shi-Xia Li et al.   ORGANIC LETTERS

Enantioselective Synthesis of Indole-Based Biaryl Atropisomers via Palladium-Catalyzed Dynamic Kinetic Intramolecular C–H Cyclization

(2017) Congfa He et al.   ACS Catalysis

Metal-Catalyzed Annulations through Activation and Cleavage of C−H Bonds

(2016) Moisés Gulías et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzed Enantiotopic C−H Activation Enables Access to P -Chiral Cyclic Phosphinamides

(2016) Yang Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-catalyzed annulation of arenes with alkynes through weak chelation-assisted C–H activation

(2016) Yudong Yang et al.   CHEMICAL COMMUNICATIONS

Enantioselective Access to Spirocyclic Sultams by Chiral Cpx -Rhodium(III)-Catalyzed Annulations

(2016) Manh V. Pham et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of axially chiral biaryl compounds by asymmetric catalytic reactions with transition metals

(2016) Pauline Loxq et al.   COORDINATION CHEMISTRY REVIEWS

Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes

(2016) Jun Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel(0)-Catalyzed Denitrogenative Transannulation of Benzotriazinones with Alkynes: Mechanistic Insights of Chemical Reactivity and Regio- and Enantioselectivity from Density Functional Theory and Experiment

(2016) Na Wang et al.   ACS Catalysis

Chiral Monophosphorus Ligands for Asymmetric Catalytic Reactions

(2016) Wenzhen Fu et al.   ACS Catalysis

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C–H Functionalizations

(2015) Baihua Ye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Synthesis of Axially Chiral Isoquinolones: Nickel-Catalyzed Denitrogenative Transannulation

(2015) Zhi-Jia Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Spiroindenes by Enol-Directed Rhodium(III)-Catalyzed CH Functionalization and Spiroannulation

(2015) Suresh Reddy Chidipudi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Atropisomeric Vinyl Arene Compounds by Palladium Catalysis: A Carbene Strategy

(2015) Jia Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric Dearomatization of Naphthols via a Rh-Catalyzed C(sp2)–H Functionalization/Annulation Reaction

(2015) Jun Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A twist of nature – the significance of atropisomers in biological systems

(2015) Jamie E. Smyth et al.   NATURAL PRODUCT REPORTS

Pd(II)-Catalyzed P(O)R1R2-Directed Asymmetric C–H Activation and Dynamic Kinetic Resolution for the Synthesis of Chiral Biaryl Phosphates

(2015) Yan-Na Ma et al.   ORGANIC LETTERS

Chiral Cyclopentadienyl Ligands Enable a Rhodium(III)-Catalyzed Enantioselective Access to Hydroxychromanes and Phthalides

(2015) Nicolai Cramer et al.   SYNLETT

The CH Activation/1,3-Diyne Strategy: Highly Selective Direct Synthesis of Diverse Bisheterocycles by RhIIICatalysis

(2014) Da-Gang Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Axial Chirality by Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes

(2014) Jun Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Axially Chiral Biaryls through Sulfoxide-Directed Asymmetric Mild CH Activation and Dynamic Kinetic Resolution

(2014) Chinmoy Kumar Hazra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral 1,2-Cyclohexane-Bridged Bis-NHC Palladium Catalysts for Asymmetric Suzuki–Miyaura Coupling: Synthesis, Characterization, and Steric Effects on Enantiocontrol

(2014) Yinle Li et al.   ORGANOMETALLICS

Enantioselective Synthesis of Axially Chiral Biaryl Monophosphine Oxides via Direct Asymmetric Suzuki Coupling and DFT Investigations of the Enantioselectivity

(2014) Yougui Zhou et al.   ACS Catalysis

Rhodium(III)-Catalyzed Redox-Neutral Coupling ofN-Phenoxyacetamides and Alkynes with Tunable Selectivity

(2013) Guixia Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Cp-Rhodium(III)-Catalyzed Asymmetric Hydroarylations of 1,1-Disubstituted Alkenes

(2013) Baihua Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric C(sp2)H Activation

(2013) Joanna Wencel-Delord et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Tunable Class of Chiral Cp Ligands for Enantioselective Rhodium(III)-Catalyzed C–H Allylations of Benzamides

(2013) Baihua Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Syntheses of Korupensamines A, B and Michellamine B by Asymmetric Suzuki-Miyaura Coupling Reactions

(2013) Guangqing Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic Kinetic Cross-Coupling Strategy for the Asymmetric Synthesis of Axially Chiral Heterobiaryls

(2013) Abel Ros et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral PEPPSI Complexes: Synthesis, Characterization, and Application in Asymmetric Suzuki–Miyaura Coupling Reactions

(2013) Laure Benhamou et al.   ORGANOMETALLICS

Aromatic C–H coupling with hindered arylboronic acids by Pd/Fe dual catalysts

(2013) Kazuya Yamaguchi et al.   Chemical Science

Recent development of direct asymmetric functionalization of inert C–H bonds

(2013) Chao Zheng et al.   RSC Advances

C–C, C–O and C–N bond formation via rhodium(iii)-catalyzed oxidative C–H activation

(2012) Guoyong Song et al.   CHEMICAL SOCIETY REVIEWS

Highly Efficient Synthesis of a Class of Novel Chiral-Bridged Atropisomeric Monophosphine Ligands via Simple Desymmetrization and Their Applications in Asymmetric Suzuki–Miyaura Coupling Reaction

(2012) Shouliang Wang et al.   ORGANIC LETTERS

Chiral Cyclopentadienyl Ligands as Stereocontrolling Element in Asymmetric C-H Functionalization

(2012) B. Ye et al.   SCIENCE

Highly Enantioselective Synthesis of Axially Chiral Biarylphosphonates: Asymmetric Suzuki-Miyaura Coupling Using High-Molecular-Weight, Helically Chiral Polyquinoxaline-Based Phosphines

(2011) Takeshi Yamamoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Low-loading asymmetric organocatalysis

(2011) Francesco Giacalone et al.   CHEMICAL SOCIETY REVIEWS

Heterocycle Synthesis via Direct C–H/N–H Coupling

(2011) Enrico T. Nadres et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

Rhodium(III)-Catalyzed Isoquinolone Synthesis: The N−O Bond as a Handle for C−N Bond Formation and Catalyst Turnover

(2010) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Axially Chiral Biaryls by the Pd-Catalyzed Suzuki−Miyaura Reaction: Substrate Scope and Quantum Mechanical Investigations

(2010) Xiaoqiang Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Diene as the Ligand for the Synthesis of Axially Chiral Compounds via Palladium-Catalyzed Suzuki−Miyaura Coupling Reaction

(2010) Shu-Sheng Zhang et al.   ORGANIC LETTERS

Total synthesis of chiral biaryl natural products by asymmetric biaryl coupling

(2009) Marisa C. Kozlowski et al.   CHEMICAL SOCIETY REVIEWS

Transition metal-catalyzed C–H activation reactions: diastereoselectivity and enantioselectivity

(2009) Ramesh Giri et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric Suzuki-Miyaura Coupling Reactions Catalyzed by Chiral Palladium Nanoparticles at Room Temperature

(2008) Koji Sawai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorescent Naphthyl- and Anthrylazoles from the Catalytic Coupling of Phenylazoles with Internal Alkynes through the Cleavage of Multiple CH Bonds

(2008) Nobuyoshi Umeda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C2-Symmetric Bis-Hydrazones as Ligands in the Asymmetric Suzuki−Miyaura Cross-Coupling

(2008) Antonio Bermejo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY