Palladium-Catalyzed Atroposelective Coupling–Cyclization of 2-Isocyanobenzamides to Construct Axially Chiral 2-Aryl- and 2,3-Diarylquinazolinones

Synthesis of Axially Chiral Styrenes through Pd-Catalyzed Asymmetric C−H Olefination Enabled by an Amino Amide Transient Directing Group

(2020) Hong Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Atroposelective Synthesis of Axially Chiral Styrenes via an Asymmetric C–H Functionalization Strategy

(2020) Liang Jin et al.   Chem

Enantioselective Synthesis of Atropisomers with Multiple Stereogenic Axes

(2020) Xiaoze Bao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Ni-Catalyzed Electrochemical Synthesis of Biaryl Atropisomers

(2020) Hui Qiu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Domino Imidoylation/Heck/C(sp2)–H Cyclization: Isocyanide Relay Strategy toward Tricyclic-Fused Heterocycles Containing an All-Carbon Quaternary Center

(2020) Fan Teng et al.   ORGANIC LETTERS

Selective C-H or N-H Imidoylative Annulation of 2-(2-Isocyanophenyl)-1H-indoles Leading to Diverse Indole-fused Scaffolds

(2019) Fan Teng et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Quinazoline and Quinazolinone Derivatives via Ligand-Promoted Ruthenium-Catalyzed Dehydrogenative and Deaminative Coupling Reaction of 2-Aminophenyl Ketones and 2-Aminobenzamides with Amines

(2019) Pandula T. Kirinde Arachchige et al.   ORGANIC LETTERS

Enantioselective Carbon-Carbon Bond Cleavage for Biaryl Atropisomers Synthesis

(2019) Ruixian Deng et al.   Chem

Rh(III)-Catalyzed Asymmetric Synthesis of Axially Chiral Biindolyls by Merging C–H Activation and Nucleophilic Cyclization

(2019) Miaomiao Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Syntheses and Properties of Some Axial and Helical Isomers of Organic Compounds

(2019) R. R. Gataullin   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Enantioselective Cacchi Reaction: Asymmetric Synthesis of Axially Chiral 2,3-Disubstituted Indoles

(2019) Yu-Ping He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Shortcuts for Electron‐Transfer through the Secondary Structure of Helical Oligo‐1,2‐Naphthylenes

(2019) Alessandro Castrogiovanni et al.   CHEMISTRY-A EUROPEAN JOURNAL

Remarkably flexible quinazolinones—synthesis and biological applications

(2019) Manne Madhava Reddy et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

(2018) Yong-Bin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Scalable, Stereocontrolled Formal Syntheses of (+)-Isoschizandrin and (+)-Steganone: Development and Applications of Palladium(II)-Catalyzed Atroposelective C−H Alkynylation

(2018) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent encounters with atropisomerism in drug discovery

(2018) Peter W. Glunz   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chiral Ferrocenyl N,N Ligands with Intramolecular Hydrogen Bonds for Highly Enantioselective Allylic Alkylations

(2018) Lin Yao et al.   ChemCatChem

Enantioselective Synthesis of Planar Chiral Pyridoferrocenes via Palladium-Catalyzed Imidoylative Cyclization Reactions

(2018) Shuang Luo et al.   ORGANIC LETTERS

Catalyst-Controlled Stereodivergent Synthesis of Atropisomeric Multiaxis Systems

(2018) Dominik Lotter et al.   ACS Central Science

Enhanced Reactivity by Torsional Strain of Cyclic Diaryliodonium in Cu-Catalyzed Enantioselective Ring-Opening Reaction

(2018) Kun Zhao et al.   Chem

Cu-Catalyzed Enantioselective Atropisomer Synthesis via Thiolative Ring Opening of Five-Membered Cyclic Diaryliodoniums

(2018) Mengqing Hou et al.   ORGANIC LETTERS

Catalytic Atropenantioselective Heteroannulation between Isocyanoacetates and Alkynyl Ketones: Synthesis of Enantioenriched Axially Chiral 3-Arylpyrroles

(2018) Sheng-Cai Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-Catalyzed Atroposelective C−H Allylation through β-O Elimination: Diverse Synthesis of Axially Chiral Biaryls

(2018) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Cyclizative Dimerization of ( ortho ‐Alkynyl Phenyl) (Methoxymethyl) Sulfides with Palladium(II) Bisoxazoline Catalyst

(2018) Cheng Peng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Atroposelective Synthesis of Arylpyrroles by Catalytic Asymmetric Paal–Knorr Reaction

(2017) Lei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic asymmetric arylation of indoles enabled by azo groups

(2017) Liang-Wen Qi et al.   Nature Chemistry

Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones

(2017) Yong-Bin Wang et al.   Nature Communications

Palladium-Catalyzed Enantioselective C(sp2)–H Imidoylation by Desymmetrization

(2017) Jian Wang et al.   ACS Catalysis

Stereoselective Arene-Forming Aldol Condensation: Synthesis of Configurationally Stable Oligo-1,2-naphthylenes

(2016) Dominik Lotter et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and Enantioselective Construction of Axially Chiral Naphthyl-Indole Skeletons

(2016) Hong-Hao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers

(2016) Scott H. Watterson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes

(2016) Jun Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Synthesis of N–C Axially Chiral Mebroqualone and Its Derivatives through Reductive Asymmetric Desymmetrization

(2016) Motohiro Hirai et al.   ORGANIC LETTERS

Addressing the Challenges in Suzuki–Miyaura Cross-Couplings by Ligand Design

(2016) Wenjun Tang et al.   SYNLETT

Chiral Monophosphorus Ligands for Asymmetric Catalytic Reactions

(2016) Wenzhen Fu et al.   ACS Catalysis

Green and practical transition metal-free one-pot conversion of substituted benzoic acids to anilines using tosyl azide

(2016) Andivelu Ilangovan et al.   Organic Chemistry Frontiers

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

Enantioselective and Enantiospecific Transition-Metal-Catalyzed Cross-Coupling Reactions of Organometallic Reagents To Construct C–C Bonds

(2015) Alan H. Cherney et al.   CHEMICAL REVIEWS

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Copper-Catalyzed Synthesis of 2-Arylquinazolinones from 2-Arylindoles with Amines or Ammoniums

(2015) Yadong Feng et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Synthesis of 3-Arylquinazolin-4(3H)-ones via Peptide-Catalyzed Atroposelective Bromination

(2015) Matthew E. Diener et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of Efficient Asymmetric Suzuki-Miyaura Cross-Coupling and Applications in Synthesis

(2015) Guangqing Xu et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Atroposelective Aldol Condensation: Synthesis of Axially Chiral Biaryls by Arene Formation

(2014) Achim Link et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Axial Chirality by Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes

(2014) Jun Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Imidoylative Cyclization of α-Isocyanoacetamides: Efficient Access to C2-Diversified Oxazoles

(2014) Jian Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

A room-temperature synthesis of 2,2′-bisoxazoles through palladium-catalyzed oxidative coupling of α-isocyanoacetamides

(2014) Jian Wang et al.   Organic Chemistry Frontiers

Catalytic C–C Bond-Forming Multi-Component Cascade or Domino Reactions: Pushing the Boundaries of Complexity in Asymmetric Organocatalysis

(2013) Chandra M. R. Volla et al.   CHEMICAL REVIEWS

Efficient Syntheses of Korupensamines A, B and Michellamine B by Asymmetric Suzuki-Miyaura Coupling Reactions

(2013) Guangqing Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New isocoumarins and alkaloid from Chinese insect medicine, Eupolyphaga sinensis Walker

(2012) Hai-Long Jiang et al.   FITOTERAPIA

Revealing Atropisomer Axial Chirality in Drug Discovery

(2011) Steven R. LaPlante et al.   ChemMedChem

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

Enantioselective Synthesis of Biphenols from 1,4-Diketones by Traceless Central-to-Axial Chirality Exchange

(2010) Fenghai Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Synthesis ofN,N-Dialkylbenzamides with Aryl-Carbonyl Axial Chirality by Rhodium-Catalyzed [2+2+2] Cycloaddition

(2008) Takeshi Suda et al.   CHEMISTRY-A EUROPEAN JOURNAL

Transition-Metal-Catalyzed Enantioselective [2+2+2] Cycloadditions for the Synthesis of Axially Chiral Biaryls

(2008) Ken Tanaka   Chemistry-An Asian Journal