Ketogenic therapy for Parkinson's disease: A systematic review and synthesis without meta-analysis of animal and human trials

Is there a special relationship between complex I activity and nigral neuronal loss in Parkinson’s disease? A critical reappraisal

(2021) Nitya Subrahmanian et al.   BRAIN RESEARCH

Therapies modulating insulin resistance in Parkinson’s disease: A cross talk

(2021) Tanya Sharma et al.   NEUROSCIENCE LETTERS

Increased Beta-Hydroxybutyrate Level Is Not Sufficient for the Neuroprotective Effect of Long-Term Ketogenic Diet in an Animal Model of Early Parkinson’s Disease. Exploration of Brain and Liver Energy Metabolism Markers

(2021) Katarzyna Z. Kuter et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease

(2021) Osama F. Elabi et al.   Journal of Neuroinflammation

Caprylic acid ameliorates rotenone induced inflammation and oxidative stress in the gut-brain axis in Zebrafish

(2021) Derya Cansız et al.   MOLECULAR BIOLOGY REPORTS

Nutritional Ketosis in Parkinson’s Disease — a Review of Remaining Questions and Insights

(2021) Alexander Choi et al.   Neurotherapeutics

Dietary Approaches to Improve Efficacy and Control Side Effects of Levodopa Therapy in Parkinson's Disease: A Systematic Review

(2021) Jikke T Boelens Keun et al.   Advances in Nutrition

Diagnosis and Treatment of Parkinson Disease

(2020) Melissa J. Armstrong et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Metabolic compartmentalization between astroglia and neurons in physiological and pathophysiological conditions of the neurovascular unit

(2020) Shinichi Takahashi   NEUROPATHOLOGY

Synthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline

(2020) Mhairi Campbell et al.   BMJ-British Medical Journal

Insulin Resistance Promotes Parkinson’s Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling

(2020) Chien-Tai Hong et al.   Cells

A Prospective Validation of the Updated Movement Disorders Society Research Criteria for Prodromal Parkinson's Disease

(2020) Nikolaos Giagkou et al.   MOVEMENT DISORDERS

To Keto or Not to Keto? A Systematic Review of Randomized Controlled Trials Assessing the Effects of Ketogenic Therapy on Alzheimer Disease

(2020) Maria G Grammatikopoulou et al.   Advances in Nutrition

Effect of ketogenic diet versus regular diet on voice quality of patients with Parkinson’s disease

(2020) Handan Koyuncu et al.   ACTA NEUROLOGICA BELGICA

A Ketone Ester Drink Enhances Endurance Exercise Performance in Parkinson’s Disease

(2020) Nicholas G. Norwitz et al.   Frontiers in Neuroscience

Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases

(2020) Nicole Jacqueline Jensen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The “great” controlling nucleotide coenzymes

(2019) Richard L. Veech et al.   IUBMB LIFE

Fishing for Parkinson’s Disease: A review of the literature

(2019) İsmail Ünal et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Motor function and the probability of prodromal Parkinson's disease in older adults

(2019) Maria I. Maraki et al.   MOVEMENT DISORDERS

Multi-Loop Model of Alzheimer Disease: An Integrated Perspective on the Wnt/GSK3β, α-Synuclein, and Type 3 Diabetes Hypotheses

(2019) Nicholas G. Norwitz et al.   Frontiers in Aging Neuroscience

Ketone Bodies in Neurological Diseases: Focus on Neuroprotection and Underlying Mechanisms

(2019) Huajun Yang et al.   Frontiers in Neurology

The Relevance of Insulin Action in the Dopaminergic System

(2019) Francesca Fiory et al.   Frontiers in Neuroscience

Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders

(2018) Katrin Augustin et al.   LANCET NEUROLOGY

Neuroketotherapeutics: A modern review of a century-old therapy

(2018) Scott J. Koppel et al.   NEUROCHEMISTRY INTERNATIONAL

Octanoic acid prevents reduction of striatal dopamine in the MPTP mouse model of Parkinson's disease.

(2018) Ilona Joniec-Maciejak et al.   Pharmacological Reports

Facilitating healthcare decisions by assessing the certainty in the evidence from preclinical animal studies

(2018) Carlijn R. Hooijmans et al.   PLoS One

Low-fat versus ketogenic diet in Parkinson's disease: A pilot randomized controlled trial

(2018) Matthew C.L. Phillips et al.   MOVEMENT DISORDERS

Ketogenic Diets for Adult Neurological Disorders

(2018) Tanya J. W. McDonald et al.   Neurotherapeutics

Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes

(2018) Charmaine Lang et al.   Cell Stem Cell

Mediterranean diet adherence is related to reduced probability of prodromal Parkinson's disease

(2018) Maria I. Maraki et al.   MOVEMENT DISORDERS

Ketone bodies mimic the life span extending properties of caloric restriction

(2017) Richard L. Veech et al.   IUBMB LIFE

A Consensus Set of Outcomes for Parkinson’s Disease from the International Consortium for Health Outcomes Measurement

(2017) Paul de Roos et al.   Journal of Parkinsons Disease

ATP Maintenance via Two Types of ATP Regulators Mitigates Pathological Phenotypes in Mouse Models of Parkinson's Disease

(2017) Masaki Nakano et al.   EBioMedicine

Accuracy of Patient and Care Partner Identification of Cognitive Impairments in Parkinson's Disease-Mild Cognitive Impairment

(2016) Jacquelynn N. Copeland et al.   MOVEMENT DISORDERS

Insulin resistance and Parkinson’s disease: A new target for disease modification?

(2016) D. Athauda et al.   PROGRESS IN NEUROBIOLOGY

Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer’s Disease

(2016) Stephen C. Cunnane et al.   Frontiers in Molecular Neuroscience

Evaluation of Models of Parkinson's Disease

(2016) Shail A. Jagmag et al.   Frontiers in Neuroscience

Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling

(2015) Shanshan Gao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

SYRCLE’s risk of bias tool for animal studies

(2014) Carlijn R Hooijmans et al.   BMC Medical Research Methodology

β-hydroxybutyrate: Much more than a metabolite

(2014) John C. Newman et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Parkinson’s disease: animal models and dopaminergic cell vulnerability

(2014) Javier Blesa et al.   Frontiers in Neuroanatomy

Mitochondrial Biology and Parkinson's Disease

(2013) C. Perier et al.   Cold Spring Harbor Perspectives in Medicine

Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines

(2012) Irene Litvan et al.   MOVEMENT DISORDERS

Caprylic Triglyceride as a Novel Therapeutic Approach to Effectively Improve the Performance and Attenuate the Symptoms Due to the Motor Neuron Loss in ALS Disease

(2012) Wei Zhao et al.   PLoS One

The effect direction plot: visual display of non-standardised effects across multiple outcome domains

(2012) Hilary J Thomson et al.   Research Synthesis Methods

Insulin resistance impairs nigrostriatal dopamine function

(2011) J.K. Morris et al.   EXPERIMENTAL NEUROLOGY

Neuroprotective and Anti-inflammatory Activities of Ketogenic Diet on MPTP-induced Neurotoxicity

(2010) Xinxin Yang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Ketogenic diet protects dopaminergic neurons against 6-OHDA neurotoxicity via up-regulating glutathione in a rat model of Parkinson's disease

(2009) Baohua Cheng et al.   BRAIN RESEARCH

Dietary glycemic index is inversely associated with the risk of Parkinson's disease: A case–control study in Japan

(2009) Kentaro Murakami et al.   NUTRITION

Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Scale presentation and clinimetric testing results

(2008) Christopher G. Goetz et al.   MOVEMENT DISORDERS

Strengths and limitations of genetic mouse models of Parkinson's disease

(2008) Marie-Francoise Chesselet et al.   PARKINSONISM & RELATED DISORDERS