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Title
Evaluation of Models of Parkinson's Disease
Authors
Keywords
-
Journal
Frontiers in Neuroscience
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2016-01-20
DOI
10.3389/fnins.2015.00503
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Note: Only part of the references are listed.- Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease
- (2015) Pan Chen et al. Metallomics
- Axon degeneration and PGC-1 -mediated protection in a zebrafish model of -synuclein toxicity
- (2014) K. C. O'Donnell et al. Disease Models & Mechanisms
- Long-Term Overexpression of Human Wild-Type and T240R Mutant Parkin in Rat Substantia Nigra Induces Progressive Dopaminergic Neurodegeneration
- (2014) Anne-Sophie Van Rompuy et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
- (2014) Mike A Nalls et al. NATURE GENETICS
- Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration
- (2014) Elpida Tsika et al. NEUROBIOLOGY OF DISEASE
- Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease
- (2014) Kuldip D. Dave et al. NEUROBIOLOGY OF DISEASE
- Methamphetamine-induced neurotoxicity: the road to Parkinson’s disease
- (2014) Bessy Thrash et al. Pharmacological Reports
- Defining Midbrain Dopaminergic Neuron Diversity by Single-Cell Gene Expression Profiling
- (2014) Jean-Francois Poulin et al. Cell Reports
- α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson’s disease and multiple system atrophy?
- (2013) Aoife P. Kiely et al. ACTA NEUROPATHOLOGICA
- Levodopa gains psychostimulant-like properties after nigral dopaminergic loss
- (2013) Michel Engeln et al. ANNALS OF NEUROLOGY
- Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity
- (2013) Bin Liu et al. EXPERIMENTAL NEUROLOGY
- DJR-1.2 of Caenorhabditis elegans is induced by DAF-16 in the dauer state
- (2013) Ju-young Lee et al. GENE
- PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
- (2013) Michael Lazarou et al. JOURNAL OF CELL BIOLOGY
- rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration
- (2013) Marusela Oliveras-Salvá et al. Molecular Neurodegeneration
- Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease
- (2013) Silke Appel-Cresswell et al. MOVEMENT DISORDERS
- A zebrafish model of PINK1 deficiency reveals key pathway dysfunction including HIF signaling
- (2013) M. Priyadarshini et al. NEUROBIOLOGY OF DISEASE
- A novel -synuclein missense mutation in Parkinson disease
- (2013) C. Proukakis et al. NEUROLOGY
- Counteraction by Nitric Oxide Synthase Inhibitor of Neurochemical Alterations of Dopaminergic System in 6-OHDA-Lesioned Rats Under l-DOPA Treatment
- (2013) Elaine Del-Bel et al. NEUROTOXICITY RESEARCH
- Parkinsonism Due to Mutations in PINK1, Parkin, and DJ-1 and Oxidative Stress and Mitochondrial Pathways
- (2013) M. R. Cookson Cold Spring Harbor Perspectives in Medicine
- (G2019S) LRRK2 activates MKK4-JNK pathway and causes degeneration of SN dopaminergic neurons in a transgenic mouse model of PD
- (2012) C-Y Chen et al. CELL DEATH AND DIFFERENTIATION
- Drosophila melanogaster in the Study of Human Neurodegeneration
- (2012) Frank Hirth CNS & Neurological Disorders-Drug Targets
- Inactivation ofPink1Genein VivoSensitizes Dopamine-producing Neurons to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and Can Be Rescued by Autosomal Recessive Parkinson Disease Genes,ParkinorDJ-1
- (2012) M. Emdadul Haque et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mimicking Phosphorylation at Serine 87 Inhibits the Aggregation of Human -Synuclein and Protects against Its Toxicity in a Rat Model of Parkinson's Disease
- (2012) A. Oueslati et al. JOURNAL OF NEUROSCIENCE
- Conditional Expression of Parkinson's Disease-Related Mutant -Synuclein in the Midbrain Dopaminergic Neurons Causes Progressive Neurodegeneration and Degradation of Transcription Factor Nuclear Receptor Related 1
- (2012) X. Lin et al. JOURNAL OF NEUROSCIENCE
- LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors
- (2012) Kelly M Hinkle et al. Molecular Neurodegeneration
- The nigrostriatal system in the presymptomatic and symptomatic stages in the MPTP monkey model: A PET, histological and biochemical study
- (2012) J. Blesa et al. NEUROBIOLOGY OF DISEASE
- Overexpression of Parkin Ameliorates Dopaminergic Neurodegeneration Induced by 1- Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice
- (2012) Minjuan Bian et al. PLoS One
- Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease
- (2012) M. W. C. Rousseaux et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development of a Unilaterally-lesioned 6-OHDA Mouse Model of Parkinson's Disease
- (2012) Sherri L. Thiele et al. Jove-Journal of Visualized Experiments
- Hypokinesia and Reduced Dopamine Levels in Zebrafish Lacking β- and γ1-Synucleins
- (2011) Chiara Milanese et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Methamphetamine neurotoxicity decreases phasic, but not tonic, dopaminergic signaling in the rat striatum
- (2011) Christopher D. Howard et al. JOURNAL OF NEUROCHEMISTRY
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- (2011) J. Dusonchet et al. JOURNAL OF NEUROSCIENCE
- Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2
- (2011) David Ramonet et al. PLoS One
- Neuropathology in Mice Expressing Mouse Alpha-Synuclein
- (2011) Claus Rieker et al. PLoS One
- Low Concentrations of Methamphetamine Can Protect Dopaminergic Cells against a Larger Oxidative Stress Injury: Mechanistic Study
- (2011) Amina El Ayadi et al. PLoS One
- Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1
- (2010) Frits Kamp et al. EMBO JOURNAL
- Expression of human A53T alpha-synuclein in the rat substantia nigra using a novel AAV1/2 vector produces a rapidly evolving pathology with protein aggregation, dystrophic neurite architecture and nigrostriatal degeneration with potential to model the pathology of Parkinson's disease
- (2010) James B Koprich et al. Molecular Neurodegeneration
- Progression of dopaminergic depletion in a model of MPTP-induced Parkinsonism in non-human primates. An 18F-DOPA and 11C-DTBZ PET study
- (2010) Javier Blesa et al. NEUROBIOLOGY OF DISEASE
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- (2010) H.L. Melrose et al. NEUROBIOLOGY OF DISEASE
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- (2010) Mareike E. Fett et al. PLoS One
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- (2010) Y. Tong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deletion of the WD40 Domain of LRRK2 in Zebrafish Causes Parkinsonism-Like Loss of Neurons and Locomotive Defect
- (2010) Donglai Sheng et al. PLoS Genetics
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- (2010) Fabio S.L. da Conceição et al. Jove-Journal of Visualized Experiments
- Mitochondrial dysfunction in Parkinson's disease
- (2009) Konstanze F. Winklhofer et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio)
- (2009) L. Flinn et al. BRAIN
- LRRK2 in Parkinson’s disease: biochemical functions
- (2009) Vasanti S. Anand et al. FEBS Journal
- Leucine-rich repeat kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease
- (2009) K. Venderova et al. HUMAN MOLECULAR GENETICS
- Caenorhabditits elegansLRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth
- (2009) Julia Sämann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice
- (2009) Tohru Kitada et al. JOURNAL OF NEUROCHEMISTRY
- α-Synuclein S129 Phosphorylation Mutants Do Not Alter Nigrostriatal Toxicity in a Rat Model of Parkinson Disease
- (2009) Nikolaus R. McFarland et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Parkin Protects against LRRK2 G2019S Mutant-Induced Dopaminergic Neurodegeneration in Drosophila
- (2009) C.-H. Ng et al. JOURNAL OF NEUROSCIENCE
- Bacterial Artificial Chromosome Transgenic Mice Expressing a Truncated Mutant Parkin Exhibit Age-Dependent Hypokinetic Motor Deficits, Dopaminergic Neuron Degeneration, and Accumulation of Proteinase K-Resistant -Synuclein
- (2009) X.-H. Lu et al. JOURNAL OF NEUROSCIENCE
- Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms
- (2009) Maria C Rodriguez-Oroz et al. LANCET NEUROLOGY
- Conditional transgenic mice expressing C-terminally truncated human α-synuclein (αSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons
- (2009) João Daher et al. Molecular Neurodegeneration
- Mutant LRRK2 R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease
- (2009) Yanping Li et al. NATURE NEUROSCIENCE
- Stereotaxical Infusion of Rotenone: A Reliable Rodent Model for Parkinson's Disease
- (2009) Nian Xiong et al. PLoS One
- R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice
- (2009) Y. Tong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Persistent MDMA-induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice
- (2008) Noelia Granado et al. JOURNAL OF NEUROCHEMISTRY
- Neurodegeneration and Motor Dysfunction in a Conditional Model of Parkinson's Disease
- (2008) S. Nuber et al. JOURNAL OF NEUROSCIENCE
- Loss of PINK1 Function Affects Development and Results in Neurodegeneration in Zebrafish
- (2008) O. Anichtchik et al. JOURNAL OF NEUROSCIENCE
- The 6-hydroxydopamine model: News from the past
- (2008) Fabio Blandini et al. PARKINSONISM & RELATED DISORDERS
- A Drosophila model for LRRK2-linked parkinsonism
- (2008) Z. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function
- (2007) Jayanth S. Chandran et al. NEUROBIOLOGY OF DISEASE
- Selective loss of nigral dopamine neurons induced by overexpression of truncated human α-synuclein in mice
- (2006) Masaki Wakamatsu et al. NEUROBIOLOGY OF AGING
- In Vivo Labeling of Mitochondrial Complex I (NADH:UbiquinoneOxidoreductase) in Rat Brain Using [3H]Dihydrorotenone
- (2003) Deepa J. Talpade et al. JOURNAL OF NEUROCHEMISTRY
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