Diet fuelling inflammatory bowel diseases: preclinical and clinical concepts

PUFA-induced metabolic enteritis as a fuel for Crohn‘s disease

(2022) Julian Schwärzler et al.   GASTROENTEROLOGY

Gut microbiome and health: mechanistic insights

(2022) Willem M de Vos et al.   GUT

Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders

(2022) Amira Metwaly et al.   Nature Reviews Gastroenterology & Hepatology

Gut microbiota-derived bile acids in intestinal immunity, inflammation, and tumorigenesis

(2022) Jie Cai et al.   Cell Host & Microbe

Discovery of bioactive microbial gene products in inflammatory bowel disease

(2022) Yancong Zhang et al.   NATURE

Human gut bacteria produce ΤΗ17-modulating bile acid metabolites

(2022) Donggi Paik et al.   NATURE

Dietary management of adults with IBD — the emerging role of dietary therapy

(2022) Jessica A. Fitzpatrick et al.   Nature Reviews Gastroenterology & Hepatology

The metabolic nature of inflammatory bowel diseases

(2022) Timon E. Adolph et al.   Nature Reviews Gastroenterology & Hepatology

First-line treatment with infliximab versus conventional treatment in children with newly diagnosed moderate-to-severe Crohn’s disease: an open-label multicentre randomised controlled trial

(2021) Maria M E Jongsma et al.   GUT

Debaryomyces is enriched in Crohn’s disease intestinal tissue and impairs healing in mice

(2021) Umang Jain et al.   SCIENCE

Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation

(2021) Ta-Chiang Liu et al.   Cell Host & Microbe

Food colorants metabolized by commensal bacteria promote colitis in mice with dysregulated expression of interleukin-23

(2021) Zhengxiang He et al.   Cell Metabolism

Reconstruction of ancient microbial genomes from the human gut

(2021) Marsha C. Wibowo et al.   NATURE

Dietary Management in Pediatric Patients with Crohn’s Disease

(2021) Luca Scarallo et al.   Nutrients

Direct impact of commonly used dietary emulsifiers on human gut microbiota

(2021) Sabrine Naimi et al.   Microbiome

Multi-omics reveal microbial determinants impacting responses to biologic therapies in inflammatory bowel disease

(2021) Jonathan Wei Jie Lee et al.   Cell Host & Microbe

Obesity is Associated With Increased Risk of Crohn’s disease, but not Ulcerative Colitis: A Pooled Analysis of Five Prospective Cohort Studies

(2021) Simon S.M. Chan et al.   Clinical Gastroenterology and Hepatology

A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults With Crohn’s Disease

(2021) James D. Lewis et al.   GASTROENTEROLOGY

Calprotectin: from biomarker to biological function

(2021) Almina Jukic et al.   GUT

Use of Fecal transplantation with a novel diet for mild to moderate active ulcerative colitis: The CRAFT UC randomized controlled trial

(2021) Chen Sarbagili Shabat et al.   Journal of Crohns & Colitis

Modified Crohn's disease exclusion diet is equally effective as exclusive enteral nutrition: Real‐world data

(2021) Tena Niseteo et al.   NUTRITION IN CLINICAL PRACTICE

The complexities of approaching nutrition in inflammatory bowel disease: current recommendations and future directions

(2021) Lindsey A Russell et al.   NUTRITION REVIEWS

Titanium dioxide particles from the diet: involvement in the genesis of inflammatory bowel diseases and colorectal cancer

(2021) Frédérick Barreau et al.   Particle and Fibre Toxicology

Dietary triggers of gut inflammation following exclusive enteral nutrition in children with Crohn’s disease: a pilot study

(2021) Konstantinos Gkikas et al.   BMC GASTROENTEROLOGY

Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response

(2021) Christine N. Spencer et al.   SCIENCE

Metabolic Influences of Gut Microbiota Dysbiosis on Inflammatory Bowel Disease

(2021) Salma Sultan et al.   Frontiers in Physiology

The Crohn's disease exclusion diet for induction and maintenance of remission in adults with mild-to-moderate Crohn's disease (CDED-AD): an open-label, pilot, randomised trial

(2021) Henit Yanai et al.   Lancet Gastroenterology & Hepatology

Long-Term Overconsumption of Fat and Sugar Causes a Partially Reversible Pre-inflammatory Bowel Disease State

(2021) Djésia Arnone et al.   Frontiers in Nutrition

Exclusive Enteral Nutrition in Adult Crohn’s Disease: an Overview of Clinical Practice and Perceived Barriers

(2021) Roberto de Sire et al.   Clinical and Experimental Gastroenterology

Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets

(2021) Antonio F. Di'Narzo et al.   GASTROENTEROLOGY

Dietary Guidance for Patients with Inflammatory Bowel Disease from the International Organization for the Study of Inflammatory Bowel Disease

(2020) A. Levine et al.   Clinical Gastroenterology and Hepatology

ESPEN practical guideline: Clinical Nutrition in inflammatory bowel disease

(2020) Stephan C. Bischoff et al.   CLINICAL NUTRITION

The effects of extra virgin olive oil and canola oil on inflammatory markers and gastrointestinal symptoms in patients with ulcerative colitis

(2020) Mehrnaz Morvaridi et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Bacterial Taxa and Functions Are Predictive of Sustained Remission Following Exclusive Enteral Nutrition in Pediatric Crohn’s Disease

(2020) Casey M A Jones et al.   INFLAMMATORY BOWEL DISEASES

Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

(2020) Aonghus Lavelle et al.   Nature Reviews Gastroenterology & Hepatology

Analysis of 61 exclusive enteral nutrition formulas used in the management of active Crohn’s disease-new insights into dietary disease triggers

(2020) Michael Logan et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Multidimensional Impact of Mediterranean Diet on IBD Patients

(2020) Fabio Chicco et al.   INFLAMMATORY BOWEL DISEASES

Dietary lipids fuel GPX4-restricted enteritis resembling Crohn’s disease

(2020) Lisa Mayr et al.   Nature Communications

Predictors of Response to Exclusive Enteral Nutrition in Newly Diagnosed Crohn´s Disease in Children: PRESENCE Study from SEGHNP

(2020) Melinda Moriczi et al.   Nutrients

Ranking microbiome variance in inflammatory bowel disease: a large longitudinal intercontinental study

(2020) Adam G Clooney et al.   GUT

The four epidemiological stages in the global evolution of inflammatory bowel disease

(2020) Gilaad G. Kaplan et al.   Nature Reviews Gastroenterology & Hepatology

Inflammatory Bowel Disease: Are Symptoms and Diet Linked?

(2020) Hannah Morton et al.   Nutrients

Dietary Fructose Alters the Composition, Localization, and Metabolism of Gut Microbiota in Association With Worsening Colitis

(2020) David C. Montrose et al.   Cellular and Molecular Gastroenterology and Hepatology

Replacing Animal Protein with Soy-Pea Protein in an “American Diet” Controls Murine Crohn Disease–Like Ileitis Regardless of Firmicutes: Bacteroidetes Ratio

(2020) Abigail Raffner Basson et al.   JOURNAL OF NUTRITION

Pathophysiology of Inflammatory Bowel Diseases

(2020) John T. Chang   NEW ENGLAND JOURNAL OF MEDICINE

Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling

(2020) Alena Fajstova et al.   Cells

Past and Future Burden of Inflammatory Bowel Diseases Based on Modeling of Population-based Data

(2019) Stephanie Coward et al.   GASTROENTEROLOGY

Vegetarian or gluten-free diets in patients with inflammatory bowel disease are associated with lower psychological well-being and a different gut microbiota, but no beneficial effects on the course of the disease

(2019) Philipp Schreiner et al.   United European Gastroenterology Journal

The gut mycobiota: insights into analysis, environmental interactions and role in gastrointestinal diseases

(2019) Mathias L. Richard et al.   Nature Reviews Gastroenterology & Hepatology

Carbohydrate Monotony as Protection and Treatment for Inflammatory Bowel Disease

(2019) Savini Britto et al.   Journal of Crohns & Colitis

Effects of dietary fat on gut microbiota and faecal metabolites, and their relationship with cardiometabolic risk factors: a 6-month randomised controlled-feeding trial

(2019) Yi Wan et al.   GUT

Environmental Risk Factors for Inflammatory Bowel Diseases: an Umbrella Review of Meta-analyses

(2019) Daniele Piovani et al.   GASTROENTEROLOGY

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

(2019) Jason Lloyd-Price et al.   NATURE

IBD prevalence in Lothian, Scotland, derived by capture–recapture methodology

(2019) Gareth-Rhys Jones et al.   GUT

Microbial genes and pathways in inflammatory bowel disease

(2019) Melanie Schirmer et al.   NATURE REVIEWS MICROBIOLOGY

A randomized, 6-week trial of low-FODMAP diet in patients with Inflammatory Bowel Disease

(2019) Giorgia Bodini et al.   NUTRITION

Diet Rich in Animal Protein Promotes Pro-inflammatory Macrophage Response and Exacerbates Colitis in Mice

(2019) Klara Kostovcikova et al.   Frontiers in Immunology

Therapeutic Opportunities in Inflammatory Bowel Disease: Mechanistic Dissection of Host-Microbiome Relationships

(2019) Damian R. Plichta et al.   CELL

Crohn’s Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial

(2019) Arie Levine et al.   GASTROENTEROLOGY

British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

(2019) Christopher Andrew Lamb et al.   GUT

A high-sugar diet rapidly enhances susceptibility to colitis via depletion of luminal short-chain fatty acids in mice

(2019) Michael Laffin et al.   Scientific Reports

The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2019) Sudabeh Alatab et al.   Lancet Gastroenterology & Hepatology

The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn’s Disease–Like Ileitis

(2018) Alexander Rodriguez-Palacios et al.   INFLAMMATORY BOWEL DISEASES

Reasoning Beyond the Potential Use of Exclusive Enteral Nutrition and Other Specified Diets in Children With Ulcerative Colitis

(2018) Ron Shaoul et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

The role of diet in the aetiopathogenesis of inflammatory bowel disease

(2018) Hamed Khalili et al.   Nature Reviews Gastroenterology & Hepatology

The Western Diet–Microbiome-Host Interaction and Its Role in Metabolic Disease

(2018) Marit Zinöcker et al.   Nutrients

OUP accepted manuscript

(2018)   Advances in Nutrition

Environment dominates over host genetics in shaping human gut microbiota

(2018) Daphna Rothschild et al.   NATURE

Microbial tryptophan catabolites in health and disease

(2018) Henrik M. Roager et al.   Nature Communications

Dietary fat, the gut microbiota, and metabolic health – A systematic review conducted within the MyNewGut project

(2018) Maike Wolters et al.   CLINICAL NUTRITION

Patient’s Dietary Beliefs and Behaviours in Inflammatory Bowel Disease

(2018) Jeanne H.M. de Vries et al.   DIGESTIVE DISEASES

Treatment of Active Crohn’s Disease With an Ordinary Food-based Diet That Replicates Exclusive Enteral Nutrition

(2018) V. Svolos et al.   GASTROENTEROLOGY

A high‑fructose diet induces epithelial barrier dysfunction and exacerbates the severity of dextran sulfate sodium‑induced colitis

(2018) Katsuto Kawabata et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Mucosal healing and bacterial composition in response to enteral nutrition versus steroid based induction therapy – a randomized prospective clinical trial in children with Crohn’s disease

(2018) Bénédicte Pigneur et al.   Journal of Crohns & Colitis

Gut microbiome structure and metabolic activity in inflammatory bowel disease

(2018) Eric A. Franzosa et al.   Nature Microbiology

Roles for Intestinal Bacteria, Viruses, and Fungi in Pathogenesis of Inflammatory Bowel Diseases and Therapeutic Approaches

(2017) R. Balfour Sartor et al.   GASTROENTEROLOGY

Adherent-invasiveEscherichia coliin inflammatory bowel disease

(2017) Carolina Palmela et al.   GUT

Differences in Outcomes Over Time With Exclusive Enteral Nutrition Compared With Steroids in Children With Mild to Moderate Crohn’s Disease: Results From the GROWTH CD Study

(2017) Noa Cohen-Dolev et al.   Journal of Crohns & Colitis

Dietary Therapy With the Crohn’s Disease Exclusion Diet is a Successful Strategy for Induction of Remission in Children and Adults Failing Biological Therapy

(2017) Rotem Sigall Boneh et al.   Journal of Crohns & Colitis

Mechanisms, Pathophysiology, and Management of Obesity

(2017) Steven B. Heymsfield et al.   NEW ENGLAND JOURNAL OF MEDICINE

Low-FODMAP diet reduces irritable bowel symptoms in patients with inflammatory bowel disease

(2017) Natalia Pedersen et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Effects of the Exclusive Enteral Nutrition on the Microbiota Profile of Patients with Crohn’s Disease: A Systematic Review

(2017) Simona Gatti et al.   Nutrients

High-Salt Diet Has a Certain Impact on Protein Digestion and Gut Microbiota: A Sequencing and Proteome Combined Study

(2017) Chao Wang et al.   Frontiers in Microbiology

Butyrate-producing bacteria supplemented in vitro to Crohn’s disease patient microbiota increased butyrate production and enhanced intestinal epithelial barrier integrity

(2017) Annelies Geirnaert et al.   Scientific Reports

Clinical and Fecal Microbial Changes With Diet Therapy in Active Inflammatory Bowel Disease

(2016) David L. Suskind et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Nutrition in Pediatric Inflammatory Bowel Disease: From Etiology to Treatment. A Systematic Review

(2016) Francesca Penagini et al.   Nutrients

Consistent Prebiotic Effect on Gut Microbiota With Altered FODMAP Intake in Patients with Crohn’s Disease: A Randomised, Controlled Cross-Over Trial of Well-Defined Diets

(2016) Emma P Halmos et al.   Clinical and Translational Gastroenterology

Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation.

(2016) Allison Agus et al.   Scientific Reports

Extensive Modulation of the Fecal Metagenome in Children With Crohn’s Disease During Exclusive Enteral Nutrition

(2015) Christopher Quince et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease

(2015) Jason M. Norman et al.   CELL

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

(2015) Caleb J. Kelly et al.   Cell Host & Microbe

High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome

(2015) Francesca De Filippis et al.   GUT

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

The Specific Carbohydrate Diet for Inflammatory Bowel Disease: A Case Series

(2015) Samir Kakodkar et al.   Journal of the Academy of Nutrition and Dietetics

Starving our Microbial Self: The Deleterious Consequences of a Diet Deficient in Microbiota-Accessible Carbohydrates

(2014) Erica D. Sonnenburg et al.   Cell Metabolism

Interactions Between the Dietary Polyunsaturated Fatty Acid Ratio and Genetic Factors Determine Susceptibility to Pediatric Crohn's Disease

(2014) Irina Costea et al.   GASTROENTEROLOGY

Partial Enteral Nutrition with a Crohnʼs Disease Exclusion Diet Is Effective for Induction of Remission in Children and Young Adults with Crohnʼs Disease

(2014) Rotem Sigall-Boneh et al.   INFLAMMATORY BOWEL DISEASES

Prevalence of a Gluten-free Diet and Improvement of Clinical Symptoms in Patients with Inflammatory Bowel Diseases

(2014) Hans H. Herfarth et al.   INFLAMMATORY BOWEL DISEASES

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

(2014) Jotham Suez et al.   NATURE

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation

(2014) Fränze Progatzky et al.   Nature Communications

Western diet induces dysbiosis with increasedE coliin CEABAC10 mice,alters host barrier function favouring AIEC colonisation

(2013) Margarita Martinez-Medina et al.   GUT

Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome

(2013) Dan Knights et al.   GUT

A decrease of the butyrate-producing speciesRoseburia hominisandFaecalibacterium prausnitziidefines dysbiosis in patients with ulcerative colitis

(2013) Kathleen Machiels et al.   GUT

Practical Strategies for Enhancing Adherence to Treatment Regimen in Inflammatory Bowel Disease

(2013) Rachel N. Greenley et al.   INFLAMMATORY BOWEL DISEASES

Exclusive enteral nutrition induces early clinical, mucosal and transmural remission in paediatric Crohn’s disease

(2013) Zubin Grover et al.   JOURNAL OF GASTROENTEROLOGY

Dietary extra virgin olive oil polyphenols supplementation modulates DSS-induced chronic colitis in mice

(2013) Susana Sánchez-Fidalgo et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Dietary intervention impact on gut microbial gene richness

(2013) Aurélie Cotillard et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Identification of secreted bacterial proteins by noncanonical amino acid tagging

(2013) A. Mahdavi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A High-Fat Diet Is Associated With Endotoxemia That Originates From the Gut

(2012) Swaroop Pendyala et al.   GASTROENTEROLOGY

The type and quantity of dietary fat and carbohydrate alter faecal microbiome and short-chain fatty acid excretion in a metabolic syndrome ‘at-risk’ population

(2012) F Fava et al.   INTERNATIONAL JOURNAL OF OBESITY

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10 −/− mice

(2012) Suzanne Devkota et al.   NATURE

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

The study on the impact of glycated pea proteins on human intestinal bacteria

(2011) Świątecka Dominika et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

GPR109A Is a G-protein-Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

(2009) M. Thangaraju et al.   CANCER RESEARCH

Prebiotics in Chronic Intestinal Inflammation

(2009) Mirjam A.C. Looijer–Van Langen et al.   INFLAMMATORY BOWEL DISEASES

Butyrate utilization by the colonic mucosa in inflammatory bowel diseases

(2009) Ronan Thibault et al.   INFLAMMATORY BOWEL DISEASES