Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets

Short chain fatty acids and its producing organisms: An overlooked therapy for IBD?

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Butyrate in Inflammatory Bowel Disease Therapy

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Big data in IBD: big progress for clinical practice

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Pathway paradigms revealed from the genetics of inflammatory bowel disease

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Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans

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Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

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TheTMEM189gene encodes plasmanylethanolamine desaturase which introduces the characteristic vinyl ether double bond into plasmalogens

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Gut microbiota density influences host physiology and is shaped by host and microbial factors

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Butyrate does not protect against inflammation-induced loss of epithelial barrier function and cytokine production in primary cell monolayers from patients with ulcerative colitis

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Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis

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Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

(2019) Jason Lloyd-Price et al.   NATURE

Zebrafish modeling of intestinal injury, bacterial exposures, and medications defines epithelial in vivo responses relevant to human inflammatory bowel disease

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Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients with Inflammatory Bowel Diseases

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Molecular Profiling of Inflammatory Bowel Disease: Is It Ready for Use in Clinical Decision-Making?

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Stimulator of interferon genes (STING) activation exacerbates experimental colitis in mice

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The Treatment of Inflammatory Bowel Disease in Patients with Selected Primary Immunodeficiencies

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Gut microbiome structure and metabolic activity in inflammatory bowel disease

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MendelianRandomization: an R package for performing Mendelian randomization analyses using summarized data

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Targeting S1P in Inflammatory Bowel Disease: New Avenues for Modulating Intestinal Leukocyte Migration

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Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies

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Alterations in lipid, amino acid, and energy metabolism distinguish Crohn’s disease from ulcerative colitis and control subjects by serum metabolomic profiling

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Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites

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Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

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The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

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PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c

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Lipidomic Profiling in Inflammatory Bowel Disease

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Mutations in Tetratricopeptide Repeat Domain 7A Result in a Severe Form of Very Early Onset Inflammatory Bowel Disease

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Interactions Between the Dietary Polyunsaturated Fatty Acid Ratio and Genetic Factors Determine Susceptibility to Pediatric Crohn's Disease

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An atlas of genetic influences on human blood metabolites

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Interleukin and interleukin receptor gene polymorphisms in inflammatory bowel diseases susceptibility

(2014) Lili Magyari   WORLD JOURNAL OF GASTROENTEROLOGY

Biomarkers in inflammatory bowel diseases: Current status and proteomics identification strategies

(2014) Tue Bennike   WORLD JOURNAL OF GASTROENTEROLOGY

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

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Metabolomics

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Functions of plasmalogen lipids in health and disease

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Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

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Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations

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Instrumental Variable Estimation of Causal Risk Ratios and Causal Odds Ratios in Mendelian Randomization Analyses

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New insights into the role of fatty acids in the pathogenesis and resolution of inflammatory bowel disease

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Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum

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