Environment dominates over host genetics in shaping human gut microbiota

Reevaluation of SNP heritability in complex human traits

(2017) Doug Speed et al.   NATURE GENETICS

Host Genetics and Gut Microbiome: Challenges and Perspectives

(2017) Alexander Kurilshikov et al.   TRENDS IN IMMUNOLOGY

Phenome-wide heritability analysis of the UK Biobank

(2017) Tian Ge et al.   PLoS Genetics

Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data

(2016) Huwenbo Shi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Model-free Estimation of Recent Genetic Relatedness

(2016) Matthew P. Conomos et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic Diversity and Association Studies in US Hispanic/Latino Populations: Applications in the Hispanic Community Health Study/Study of Latinos

(2016) Matthew P. Conomos et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic Determinants of the Gut Microbiome in UK Twins

(2016) Julia K. Goodrich et al.   Cell Host & Microbe

Reference-based phasing using the Haplotype Reference Consortium panel

(2016) Po-Ru Loh et al.   NATURE GENETICS

Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota

(2016) Jun Wang et al.   NATURE GENETICS

The effect of host genetics on the gut microbiome

(2016) Marc Jan Bonder et al.   NATURE GENETICS

Association of host genome with intestinal microbial composition in a large healthy cohort

(2016) Williams Turpin et al.   NATURE GENETICS

Linear mixed model for heritability estimation that explicitly addresses environmental variation

(2016) David Heckerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

(2016) Alexandra Zhernakova et al.   SCIENCE

Population-level analysis of gut microbiome variation

(2016) Gwen Falony et al.   SCIENCE

Pedigree- and SNP-Associated Genetics and Recent Environment are the Major Contributors to Anthropometric and Cardiometabolic Trait Variation

(2016) Charley Xia et al.   PLoS Genetics

Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome

(2016) Hailiang Xie et al.   Cell Systems

Testing in Microbiome-Profiling Studies with MiRKAT, the Microbiome Regression-Based Kernel Association Test

(2015) Ni Zhao et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Personalized Nutrition by Prediction of Glycemic Responses

(2015) David Zeevi et al.   CELL

The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood LipidsNovelty and Significance

(2015) Jingyuan Fu et al.   CIRCULATION RESEARCH

Robust Inference of Population Structure for Ancestry Prediction and Correction of Stratification in the Presence of Relatedness

(2015) Matthew P. Conomos et al.   GENETIC EPIDEMIOLOGY

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Comparison of Heritability of Cystatin C- and Creatinine-Based Estimates of Kidney Function and Their Relation to Heritability of Cardiovascular Disease

(2015) J. Arpegard et al.   Journal of the American Heart Association

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

A General Unified Framework to Assess the Sampling Variance of Heritability Estimates Using Pedigree or Marker-Based Relationships

(2014) P. M. Visscher et al.   GENETICS

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

Advantages and pitfalls in the application of mixed-model association methods

(2014) Jian Yang et al.   NATURE GENETICS

Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins

(2014) Shai Carmi et al.   Nature Communications

Further Improvements to Linear Mixed Models for Genome-Wide Association Studies

(2014) Christian Widmer et al.   Scientific Reports

PathoScope 2.0: a complete computational framework for strain identification in environmental or clinical sequencing samples

(2014) Changjin Hong et al.   Microbiome

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Prediction of Complex Human Traits Using the Genomic Best Linear Unbiased Predictor

(2013) Gustavo de los Campos et al.   PLoS Genetics

Using Extended Genealogy to Estimate Components of Heritability for 23 Quantitative and Dichotomous Traits

(2013) Noah Zaitlen et al.   PLoS Genetics

Cohabiting family members share microbiota with one another and with their dogs

(2013) Se Jin Song et al.   eLife

The Impact of the Gut Microbiota on Human Health: An Integrative View

(2012) Jose C. Clemente et al.   CELL

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Improved linear mixed models for genome-wide association studies

(2012) Jennifer Listgarten et al.   NATURE METHODS

Metagenomic microbial community profiling using unique clade-specific marker genes

(2012) Nicola Segata et al.   NATURE METHODS

The GEM mapper: fast, accurate and versatile alignment by filtration

(2012) Santiago Marco-Sola et al.   NATURE METHODS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Heritability and Genetic Correlations Explained by Common SNPs for Metabolic Syndrome Traits

(2012) Shashaank Vattikuti et al.   PLoS Genetics

Moving pictures of the human microbiome

(2011) J Gregory Caporaso et al.   GENOME BIOLOGY

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Robust relationship inference in genome-wide association studies

(2010) Ani Manichaikul et al.   BIOINFORMATICS

The genome-wide structure of the Jewish people

(2010) Doron M. Behar et al.   NATURE

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

(2010) Amy Strange et al.   NATURE GENETICS

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Reproducible Community Dynamics of the Gastrointestinal Microbiota following Antibiotic Perturbation

(2009) D. A. Antonopoulos et al.   INFECTION AND IMMUNITY

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Lactose digestion and the evolutionary genetics of lactase persistence

(2008) Catherine J. E. Ingram et al.   HUMAN GENETICS

Heritability in the genomics era — concepts and misconceptions

(2008) Peter M. Visscher et al.   NATURE REVIEWS GENETICS