Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer

Bioinformatic Analysis for the Prognostic Implication of Genes Encoding Epithelial Sodium Channel in Cervical Cancer

(2022) Changho Song et al.   International Journal of General Medicine

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

HOXD9‑induced SCNN1A upregulation promotes pancreatic cancer cell proliferation, migration and predicts prognosis by regulating epithelial‑mesenchymal transformation

(2021) Jinhai Chang et al.   Molecular Medicine Reports

Acid-Sensing Ion Channels: Expression and Function in Resident and Infiltrating Immune Cells in the Central Nervous System

(2021) Victoria S. Foster et al.   Frontiers in Cellular Neuroscience

Topography and motion of acid-sensing ion channel intracellular domains

(2021) Tyler Couch et al.   eLife

Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival Prognosis

(2021) Maxim L. Bychkov et al.   Biomedicines

Recombinant Analogue of the Human Protein SLURP-1 Inhibits the Growth of Multicellular Spheroids Reconstructed from Carcinoma Cells

(2020) M. L. Bychkov et al.   Doklady Biochemistry and Biophysics

Water‐soluble variant of human Lynx1 positively modulates synaptic plasticity and ameliorates cognitive impairment associated with α7‐nAChR dysfunction

(2020) Zakhar O. Shenkarev et al.   JOURNAL OF NEUROCHEMISTRY

Visualizing and interpreting cancer genomics data via the Xena platform

(2020) Mary J. Goldman et al.   NATURE BIOTECHNOLOGY

Animal, Herb, and Microbial Toxins for Structural and Pharmacological Study of Acid-Sensing Ion Channels

(2020) Dmitry I. Osmakov et al.   Frontiers in Pharmacology

Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a

(2020) Maxim Bychkov et al.   Cancers

pH-Channeling in Cancer: How pH-Dependence of Cation Channels Shapes Cancer Pathophysiology

(2020) Zoltán Pethő et al.   Cancers

Regulating ENaC's gate

(2019) Thomas R Kleyman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Human secreted proteins SLURP-1 and SLURP-2 control the growth of epithelial cancer cells via interactions with nicotinic acetylcholine receptors

(2018) E N Lyukmanova et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dual actions of Psalmotoxin at ASIC1a and ASIC2a heteromeric channels (ASIC1a/2a)

(2018) Yi Liu et al.   Scientific Reports

The acid-sensing ion channel, ASIC2, promotes invasion and metastasis of colorectal cancer under acidosis by activating the calcineurin/NFAT1 axis

(2017) Zhi-hang Zhou et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Modeling Physiological Events in 2D vs. 3D Cell Culture

(2017) Kayla Duval et al.   PHYSIOLOGY

Towards universal approach for bacterial production of three-finger Ly6/uPAR proteins: Case study of cytotoxin I from cobra N. oxiana

(2017) M.A. Shulepko et al.   PROTEIN EXPRESSION AND PURIFICATION

Acid-sensing ion channels contribute to the effect of extracellular acidosis on proliferation and migration of A549 cells

(2017) Yu Wu et al.   TUMOR BIOLOGY

ASIC1 and ASIC3 contribute to acidity-induced EMT of pancreatic cancer through activating Ca2+/RhoA pathway

(2017) Shuai Zhu et al.   Cell Death & Disease

Acidic cellular microenvironment modifies carcinogen-induced DNA damage and repair

(2016) Q. Shi et al.   ARCHIVES OF TOXICOLOGY

Amiloride Analogs as ASIC1a Inhibitors

(2016) Tian-Dong Leng et al.   CNS Neuroscience & Therapeutics

Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT–mTOR–S6K signaling and drug responses

(2016) Angelika Riedl et al.   JOURNAL OF CELL SCIENCE

ASIC1a mediates the drug resistance of human hepatocellular carcinoma via the Ca2+/PI3-kinase/AKT signaling pathway

(2016) Yihao Zhang et al.   LABORATORY INVESTIGATION

Functional and pharmacological characterization of two different ASIC1a/2a heteromers reveals their sensitivity to the spider toxin PcTx1

(2016) Niko Joeres et al.   Scientific Reports

Regulation of breast tumorigenesis through acid sensors

(2015) S C Gupta et al.   ONCOGENE

Evaluating tumor metastatic potential by imaging intratumoral acidosisviapH-activatable near-infrared fluorescent probe

(2014) Lu Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Acidity Generated by the Tumor Microenvironment Drives Local Invasion

(2013) V. Estrella et al.   CANCER RESEARCH

Venom toxins in the exploration of molecular, physiological and pathophysiological functions of acid-sensing ion channels

(2013) Anne Baron et al.   TOXICON

Black mamba venom peptides target acid-sensing ion channels to abolish pain

(2012) Sylvie Diochot et al.   NATURE

Interaction of ASIC1 and ENaC subunits in human glioma cells and rat astrocytes

(2011) Niren Kapoor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Glioma-specific Cation Conductance Regulates Migration and Cell Cycle Progression

(2011) Arun K. Rooj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Knockdown of ASIC1 and Epithelial Sodium Channel Subunits Inhibits Glioblastoma Whole Cell Current and Cell Migration

(2009) Niren Kapoor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

(2009) Julian R. Molina et al.   MAYO CLINIC PROCEEDINGS

Regulation of ASIC activity by ASIC4 - new insights into ASIC channel function revealed by a yeast two-hybrid assay

(2008) Emmanuelle Donier et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

SV40: Cell transformation and tumorigenesis

(2008) James M. Pipas   VIROLOGY