Acidic cellular microenvironment modifies carcinogen-induced DNA damage and repair

Inflammation-associated extracellular β-glucuronidase alters cellular responses to the chemical carcinogen benzo[a]pyrene

(2015) Q. Shi et al.   ARCHIVES OF TOXICOLOGY

COPD and squamous cell lung cancer: aberrant inflammation and immunity is the common link

(2015) Steven Bozinovski et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hypoxia diminishes the detoxification of the environmental mutagen benzo[a]pyrene

(2014) M. A. Schults et al.   MUTAGENESIS

Comet assay to measure DNA repair: approach and applications

(2014) Amaya Azqueta et al.   Frontiers in Genetics

The essential comet assay: a comprehensive guide to measuring DNA damage and repair

(2013) Amaya Azqueta et al.   ARCHIVES OF TOXICOLOGY

How does the metabolism of tumour cells differ from that of normal cells

(2013) Nívea Dias Amoêdo et al.   BIOSCIENCE REPORTS

Acidic extracellular microenvironment and cancer

(2013) Yasumasa Kato et al.   Cancer Cell International

Genetic polymorphisms in catalase and CYP1B1 determine DNA adduct formation by benzo(a)pyrene ex vivo

(2013) Marten A. Schults et al.   MUTAGENESIS

Use of the γ-H2AX Assay to Investigate DNA Repair Dynamics Following Multiple Radiation Exposures

(2013) Luca G. Mariotti et al.   PLoS One

Inflammatory mediators accelerate metabolism of benzo[a]pyrene in rat alveolar type II cells: The role of enhanced cytochrome P450 1B1 expression

(2013) Lenka Šmerdová et al.   TOXICOLOGY

Acidic tumor microenvironment and pH-sensing G protein-coupled receptors

(2013) Calvin R. Justus et al.   Frontiers in Physiology

Loss of VHL in RCC Reduces Repair and Alters Cellular Response to Benzo[a]pyrene

(2013) Marten A. Schults et al.   Frontiers in Oncology

Histone Acetylation Regulates Intracellular pH

(2012) Matthew A. McBrian et al.   MOLECULAR CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Acidic Environment Leads to ROS-Induced MAPK Signaling in Cancer Cells

(2011) Anne Riemann et al.   PLoS One

Benzo[a]pyrene and tumor necrosis factor-α coordinately increase genotoxic damage and the production of proinflammatory mediators in alveolar epithelial type II cells

(2011) Lenka Umannová et al.   TOXICOLOGY LETTERS

In Vitro Effects of Acid and Pepsin on Mouse Middle Ear Epithelial Cell Viability and MUC5B Gene Expression

(2010) Bradley B. Block et al.   ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

Diminished Carcinogen Detoxification Is a Novel Mechanism for Hypoxia-inducible Factor 1-mediated Genetic Instability

(2010) Marten A. Schults et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer

(2010) Johanna Chiche et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lung inflammation is associated with reduced pulmonary nucleotide excision repair in vivo

(2009) N. Gungor et al.   MUTAGENESIS

Oxidative Stress and Oxidative Damage in Carcinogenesis

(2009) James E. Klaunig et al.   TOXICOLOGIC PATHOLOGY

Electrical Stimulation for Long-Bone Fracture-Healing: A Meta-Analysis of Randomized Controlled Trials

(2008) Brent Mollon et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Tumor necrosis factor-α potentiates genotoxic effects of benzo[a]pyrene in rat liver epithelial cells through upregulation of cytochrome P450 1B1 expression

(2008) Lenka Umannová et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

An optimized method for measurement of gamma-H2AX in blood mononuclear and cultured cells

(2008) Aida Muslimovic et al.   Nature Protocols