Amiloride Analogs as ASIC1a Inhibitors

X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel

(2014) Isabelle Baconguis et al.   CELL

Local Anesthetic Lidocaine Inhibits TRPM7 Current and TRPM7-Mediated Zinc Toxicity

(2014) Tian-Dong Leng et al.   CNS Neuroscience & Therapeutics

Proton-sensitive cation channels and ion exchangers in ischemic brain injury: New therapeutic targets for stroke?

(2014) Tiandong Leng et al.   PROGRESS IN NEUROBIOLOGY

Subunit and Frequency-Dependent Inhibition of Acid Sensing Ion Channels by Local Anesthetic Tetracaine

(2013) Tiandong Leng et al.   Molecular Pain

The pharmacology and therapeutic potential of small molecule inhibitors of acid-sensing ion channels in stroke intervention

(2012) Tian-dong Leng et al.   ACTA PHARMACOLOGICA SINICA

ENaCs and ASICs as therapeutic targets

(2012) Yawar J. Qadri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Acidosis, Acid-Sensing Ion Channels, and Neuronal Cell Death

(2011) Yi-Zhi Wang et al.   MOLECULAR NEUROBIOLOGY

The NCX3 Isoform of the Na+/Ca2+ Exchanger Contributes to Neuroprotection Elicited by Ischemic Postconditioning

(2010) Giuseppe Pignataro et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Conformer Generation with OMEGA: Algorithm and Validation Using High Quality Structures from the Protein Databank and Cambridge Structural Database

(2010) Paul C. D. Hawkins et al.   Journal of Chemical Information and Modeling

Diarylamidines: High potency inhibitors of acid-sensing ion channels

(2010) Xuanmao Chen et al.   NEUROPHARMACOLOGY

Differential Involvement of ASIC1a in the Basolateral Amygdala in Fear Memory and Unconditioned Fear Responses

(2009) S. Gregoire et al.   JOURNAL OF NEUROSCIENCE

ASIC3, a sensor of acidic and primary inflammatory pain

(2008) Emmanuel Deval et al.   EMBO JOURNAL

Gene inactivation of Na+/H+exchanger isoform 1 attenuates apoptosis and mitochondrial damage following transient focal cerebral ischemia

(2008) Yanping Wang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Late expression of Na+/H+ exchanger 1 (NHE1) and neuroprotective effects of NHE inhibitor in the gerbil hippocampal CA1 region induced by transient ischemia

(2008) In Koo Hwang et al.   EXPERIMENTAL NEUROLOGY

Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism

(2008) Hon Kit Wong et al.   HUMAN MOLECULAR GENETICS

Na+/Ca2+ exchanger 2 is neuroprotective by exporting Ca2+ during a transient focal cerebral ischemia in the mouse

(2007) Daejong Jeon et al.   CELL CALCIUM