A haem-sequestering plant peptide promotes iron uptake in symbiotic bacteria

Heme sequestration as an effective strategy for the suppression of tumor growth and progression

(2021) Tianyuan Wang et al.   MOLECULAR CANCER THERAPEUTICS

Interplay between membrane active host defense peptides and heme modulates their assemblies and in vitro activity

(2021) Tünde Juhász et al.   Scientific Reports

Insights into irr and rirA gene regulation on the virulence of Brucella melitensis M5-90.

(2020) Huan Zhang et al.   CANADIAN JOURNAL OF MICROBIOLOGY

The Multifaceted Role of Heme in Cancer

(2020) Veronica Fiorito et al.   Frontiers in Oncology

Toxoplasma gondii requires its plant-like heme biosynthesis pathway for infection

(2020) Amy Bergmann et al.   PLoS Pathogens

Unexplored Arsenals of Legume Peptides With Potential for Their Applications in Medicine and Agriculture

(2020) Rui M. Lima et al.   Frontiers in Microbiology

Cysteine‐rich antimicrobial peptides from plants: The future of antimicrobial therapy

(2020) Shilpi Srivastava et al.   PHYTOTHERAPY RESEARCH

Heme Uptake and Utilization by Gram-Negative Bacterial Pathogens

(2019) Kaylie L. Richard et al.   Frontiers in Cellular and Infection Microbiology

Haem Biology in Metazoan Parasites – ‘The Bright Side of Haem’

(2019) Jan Perner et al.   TRENDS IN PARASITOLOGY

The Protective Role of Heme Oxygenase-1 in Atherosclerotic Diseases

(2019) Yoshimi Kishimoto et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sinorhizobium meliloti YbeY is a zinc-dependent single-strand specific endoribonuclease that plays an important role in 16S ribosomal RNA processing

(2019) Vignesh M P Babu et al.   NUCLEIC ACIDS RESEARCH

Heme and hemoglobin utilization by Mycobacterium tuberculosis

(2019) Avishek Mitra et al.   Nature Communications

Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries

(2018) Ashley T. Tucker et al.   CELL

Role of heme in lung bacterial infection after trauma hemorrhage and stored red blood cell transfusion: A preclinical experimental study

(2018) Brant M. Wagener et al.   PLOS MEDICINE

Unraveling the Role of Heme in Neurodegeneration

(2018) Deborah Chiabrando et al.   Frontiers in Neuroscience

Characterization of plasma labile heme in hemolytic conditions

(2017) Zélia Gouveia et al.   FEBS Journal

A multi-purpose toolkit to enable advanced genome engineering in plants

(2017) Tomas Cermak et al.   PLANT CELL

Morphotype of bacteroids in different legumes correlates with the number and type of symbiotic NCR peptides

(2017) Jesús Montiel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensing iron availability via the fragile [4Fe–4S] cluster of the bacterial transcriptional repressor RirA

(2017) Ma Teresa Pellicer Martinez et al.   Chemical Science

Genome-Wide Sensitivity Analysis of the Microsymbiont Sinorhizobium meliloti to Symbiotically Important, Defensin-Like Host Peptides

(2017) Markus F. F. Arnold et al.   mBio

Heme as a Target for Therapeutic Interventions

(2017) Stephan Immenschuh et al.   Frontiers in Pharmacology

Analysis of Heme Iron Coordination in DGCR8: The Heme-Binding Component of the Microprocessor Complex

(2016) Hazel M. Girvan et al.   BIOCHEMISTRY

Heme interacts with histidine- and tyrosine-based protein motifs and inhibits enzymatic activity of chloramphenicol acetyltransferase from Escherichia coli

(2016) Hans Henning Brewitz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Haptoglobin or Hemopexin Therapy Prevents Acute Adverse Effects of Resuscitation After Prolonged Storage of Red CellsClinical Perspective

(2016) Jan A. Graw et al.   CIRCULATION

TheBradyrhizobium japonicumFerrous Iron Transporter FeoAB Is Required for Ferric Iron Utilization in Free Living Aerobic Cells and for Symbiosis

(2016) Siva Sankari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytochrome c peroxidase activity of heme bound amyloid β peptides

(2016) Manas Seal et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Stored blood: how old is too old?

(2016) Janet S. Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Disulfide cross-linking influences symbiotic activities of nodule peptide NCR247

(2016) Mohammed Shabab et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antimicrobial nodule-specific cysteine-rich peptides disturb the integrity of bacterial outer and inner membranes and cause loss of membrane potential

(2016) Kata R. Mikuláss et al.   Annals of Clinical Microbiology and Antimicrobials

Alzheimer’s Disease: A Heme–Aβ Perspective

(2015) Chandradeep Ghosh et al.   ACCOUNTS OF CHEMICAL RESEARCH

Perception and Homeostatic Control of Iron in the Rhizobia and Related Bacteria

(2015) Mark R. O'Brian   Annual Review of Microbiology

Bradyrhizobium BclA Is a Peptide Transporter Required for Bacterial Differentiation in Symbiosis with Aeschynomene Legumes

(2015) Ibtissem Guefrachi et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Loss of the nodule-specific cysteine rich peptide, NCR169, abolishes symbiotic nitrogen fixation in theMedicago truncatula dnf7mutant

(2015) Beatrix Horváth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An antimicrobial peptide essential for bacterial survival in the nitrogen-fixing symbiosis

(2015) Minsoo Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An integrated analysis of plant and bacterial gene expression in symbiotic root nodules using laser-capture microdissection coupled to RNA sequencing

(2014) Brice Roux et al.   PLANT JOURNAL

Medicago truncatula symbiotic peptide NCR247 contributes to bacteroid differentiation through multiple mechanisms

(2014) A. Farkas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host plant peptides elicit a transcriptional response to control theSinorhizobium meliloticell cycle during symbiosis

(2014) Jon Penterman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fixating on metals: new insights into the role of metals in nodulation and symbiotic nitrogen fixation

(2014) Manuel González-Guerrero et al.   Frontiers in Plant Science

Analysis of Fe(III) Heme Binding to Cysteine-Containing Heme-Regulatory Motifs in Proteins

(2013) Toni Kühl et al.   ACS Chemical Biology

Hemopexin Therapy Improves Cardiovascular Function by Preventing Heme-Induced Endothelial Toxicity in Mouse Models of Hemolytic Diseases

(2013) Francesca Vinchi et al.   CIRCULATION

Make It, Take It, or Leave It: Heme Metabolism of Parasites

(2013) Luděk Kořený et al.   PLoS Pathogens

Iron: an essential micronutrient for the legume-rhizobium symbiosis

(2013) Ella M. Brear et al.   Frontiers in Plant Science

TwoSinorhizobium melilotiglutaredoxins regulate iron metabolism and symbiotic bacteroid differentiation

(2012) Sofiane M. Benyamina et al.   ENVIRONMENTAL MICROBIOLOGY

Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing

(2012) I. Barr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and treatment of heme depletion attributed to overexpression of a lineage of evolved P450 monooxygenases

(2012) J. K. Michener et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heme Cytotoxicity and the Pathogenesis of Immune-Mediated Inflammatory Diseases

(2012) Rasmus Larsen et al.   Frontiers in Pharmacology

Antiparallel and Interlinked Control of Cellular Iron Levels by the Irr and RirA Regulators of Agrobacterium tumefaciens

(2011) M. E. Hibbing et al.   JOURNAL OF BACTERIOLOGY

DiGeorge Critical Region 8 (DGCR8) Is a Double-cysteine-ligated Heme Protein

(2011) Ian Barr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding of cysteine thiolate to the Fe(III) heme complex is critical for the function of heme sensor proteins

(2011) Toru Shimizu   JOURNAL OF INORGANIC BIOCHEMISTRY

Structural analysis of heme proteins: implications for design and prediction

(2011) Ting Li et al.   BMC STRUCTURAL BIOLOGY

Heme-responsive DNA Binding by the Global Iron Regulator Irr fromRhizobium leguminosarum

(2010) Chloe Singleton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plant Peptides Govern Terminal Differentiation of Bacteria in Symbiosis

(2010) W. Van de Velde et al.   SCIENCE

A Central Role for Free Heme in the Pathogenesis of Severe Sepsis

(2010) R. Larsen et al.   Science Translational Medicine

Conotoxins: natural product drug leads

(2009) Reena Halai et al.   NATURAL PRODUCT REPORTS

Plant flotillins are required for infection by nitrogen-fixing bacteria

(2009) C. H. Haney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing the role of the proximal heme ligand in cytochrome P450cam by recombinant incorporation of selenocysteine

(2009) C. Aldag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heme oxygenase-1 affords protection against noncerebral forms of severe malaria

(2009) E. Seixas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Determinants of a Symbiotic Chronic Infection

(2008) Katherine E. Gibson et al.   Annual Review of Genetics

Essential Role for the BacA Protein in the Uptake of a Truncated Eukaryotic Peptide in Sinorhizobium meliloti

(2008) V. L. Marlow et al.   JOURNAL OF BACTERIOLOGY

A novel bicistronic vector for overexpressing Mycobacterium tuberculosis proteins in Escherichia coli

(2008) Yin Guo et al.   PROTEIN EXPRESSION AND PURIFICATION