A Central Role for Free Heme in the Pathogenesis of Severe Sepsis

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

Heme Scavenging and the Other Facets of Hemopexin

(2009) Emanuela Tolosano et al.   ANTIOXIDANTS & REDOX SIGNALING

Receptor targeting of hemoglobin mediated by the haptoglobins: roles beyond heme scavenging

(2009) M. J. Nielsen et al.   BLOOD

Beneficial effects of the heme oxygenase-1/carbon monoxide system in patients with severe sepsis/septic shock

(2009) Shoji Takaki et al.   INTENSIVE CARE MEDICINE

Oxidized Hemoglobin Is an Endogenous Proinflammatory Agonist That Targets Vascular Endothelial Cells

(2009) Gabriela Silva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heme–Hemopexin Complex Attenuates Neuronal Cell Death and Stroke Damage

(2009) Rung-chi Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Hemopexin down-regulates LPS-induced proinflammatory cytokines from macrophages

(2009) Xueya Liang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Damage control in host-pathogen interactions

(2009) R. Medzhitov   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heme oxygenase-1 affords protection against noncerebral forms of severe malaria

(2009) E. Seixas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heme oxygenase-1: from biology to therapeutic potential

(2009) Miguel P. Soares et al.   TRENDS IN MOLECULAR MEDICINE

High-Mobility Group Box 1 Contributes to Lethality of Endotoxemia in Heme Oxygenase-1–Deficient Mice

(2008) Rina Takamiya et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Inflammatory Response to Cell Death

(2008) Kenneth L. Rock et al.   Annual Review of Pathology-Mechanisms of Disease

Heme oxygenase-1–derived carbon monoxide enhances the host defense response to microbial sepsis in mice

(2008) Su Wol Chung et al.   JOURNAL OF CLINICAL INVESTIGATION

A central role for free heme in the pathogenesis of severe malaria: the missing link?

(2008) Ana Ferreira et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Cryptochromes Define a Novel Circadian Clock Mechanism in Monarch Butterflies That May Underlie Sun Compass Navigation

(2008) Haisun Zhu et al.   PLOS BIOLOGY