The Protective Role of Heme Oxygenase-1 in Atherosclerotic Diseases

RNA-sequencing in human HepG2 hepatocytes reveals PPARα mediates transcriptome responsiveness of bilirubin.

(2019) Darren M Gordon et al.   PHYSIOLOGICAL GENOMICS

Activation of Nrf2/HO-1 Pathway and Human Atherosclerotic Plaque Vulnerability:an In Vitro and In Vivo Study

(2019) Fiorelli et al.   Cells

The macrophage heme-heme oxygenase-1 system and its role in inflammation

(2018) Vijith Vijayan et al.   BIOCHEMICAL PHARMACOLOGY

Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions

(2018) Valeria Pittala et al.   CURRENT MEDICINAL CHEMISTRY

Plasma Heme Oxygenase-1 Levels in Patients with Coronary and Peripheral Artery Diseases

(2018) Yoshimi Kishimoto et al.   DISEASE MARKERS

Plasma Heme Oxygenase-1 Levels and Carotid Atherosclerosis

(2018) Yoshimi Kishimoto et al.   STROKE

Therapeutic Potential of Caffeic Acid Phenethyl Ester (CAPE) in Diabetes

(2018) Valeria Pittalá et al.   CURRENT MEDICINAL CHEMISTRY

NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches

(2018) Farzane Sivandzade et al.   Redox Biology

Oxidative Stress in Cardiovascular Diseases: Involvement of Nrf2 Antioxidant Redox Signaling in Macrophage Foam Cells Formation

(2017) Bee Ooi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Heme as a Target for Therapeutic Interventions

(2017) Stephan Immenschuh et al.   Frontiers in Pharmacology

Plasma heme oxygenase-1 is decreased in peripheral artery disease patients

(2016) Salvatore Santo Signorelli et al.   Molecular Medicine Reports

Translational Significance of Heme Oxygenase in Obesity and Metabolic Syndrome

(2016) Nader G. Abraham et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Bilirubin Binding to PPARα Inhibits Lipid Accumulation

(2016) David E. Stec et al.   PLoS One

Association of serum total bilirubin level with severity of coronary atherosclerosis is linked to systemic inflammation

(2015) Mehmet Kadri Akboga et al.   ATHEROSCLEROSIS

Haeme oxygenase signalling pathway: implications for cardiovascular disease

(2015) Laura E. Fredenburgh et al.   EUROPEAN HEART JOURNAL

Bilirubin is independently associated with oxidized LDL levels in young obese patients

(2015) Henrique Nascimento et al.   Diabetology & Metabolic Syndrome

Association Between Heme Oxygenase 1 Gene Promoter Polymorphisms and Susceptibility to Coronary Artery Disease: A HuGE Review and Meta-Analysis

(2014) Huaiyu Qiao et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Heme oxygenase-1 overexpression exacerbates heart failure with aging and pressure overload but is protective against isoproterenol-induced cardiomyopathy in mice

(2014) Melissa A. Allwood et al.   CARDIOVASCULAR PATHOLOGY

Heme Oxygenase-1 Induction Improves Cardiac Function following Myocardial Ischemia by Reducing Oxidative Stress

(2014) Yossi Issan et al.   PLoS One

Heme Oxygenase-1 Is Required for Angiogenic Function of Bone Marrow-Derived Progenitor Cells: Role in Therapeutic Revascularization

(2013) Anna Grochot-Przeczek et al.   ANTIOXIDANTS & REDOX SIGNALING

Elevated serum bilirubin levels are inversely associated with coronary artery atherosclerosis

(2013) Seung Joo Kang et al.   ATHEROSCLEROSIS

The absence of macrophage Nrf2 promotes early atherogenesis

(2013) Anna-Kaisa Ruotsalainen et al.   CARDIOVASCULAR RESEARCH

Total bilirubin in young men and women: Association with risk markers for cardiovascular diseases

(2013) Marina Stojanov et al.   CLINICAL BIOCHEMISTRY

Association between hemoglobin scavenger receptor and heme oxygenase–1–related anti-inflammatory mediators in human coronary stable and unstable plaques

(2013) Kei Yunoki et al.   HUMAN PATHOLOGY

Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis

(2013) S. Stender et al.   JOURNAL OF INTERNAL MEDICINE

Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis

(2013) F Gerald R Fowkes et al.   LANCET

Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21

(2013) Terry D. Hinds et al.   Obesity

Inverse relationship between serum total bilirubin levels and severity of disease in patients with stable coronary artery disease

(2012) Murat Turfan et al.   CORONARY ARTERY DISEASE

Reduced circulating oxidized LDL is associated with hypocholesterolemia and enhanced thiol status in Gilbert syndrome

(2012) Ai-Ching Boon et al.   FREE RADICAL BIOLOGY AND MEDICINE

Laminar Flow Activation of ERK5 Protein in Vascular Endothelium Leads to Atheroprotective Effect via NF-E2-related Factor 2 (Nrf2) Activation

(2012) Miso Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vasculitis, Atherosclerosis, and Altered HDL Composition in Heme-Oxygenase-1-Knockout Mice

(2012) Kazunobu Ishikawa et al.   International Journal of Hypertension

Short (GT) n repeats in heme oxygenase-1 gene promoter are associated with lower risk of coronary heart disease in subjects with high levels of oxidative stress

(2011) Mu Chen et al.   CELL STRESS & CHAPERONES

Heme oxygenase-1 inhibits progression and destabilization of vulnerable plaques in a rabbit model of atherosclerosis

(2011) Tingting Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hsp60 and heme oxygenase-1 (Hsp32) in acute myocardial infarction

(2011) Giuseppina Novo et al.   Translational Research

NF-E2–Related Factor 2 Promotes Atherosclerosis by Effects on Plasma Lipoproteins and Cholesterol Transport That Overshadow Antioxidant Protection

(2010) Berenice Barajas et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cardioprotective and Antiapoptotic Effects of Heme Oxygenase-1 in the Failing Heart

(2010) Guangwu Wang et al.   CIRCULATION

Serum Bilirubin and Genes Controlling Bilirubin Concentrations as Biomarkers for Cardiovascular Disease

(2010) J.-P. Lin et al.   CLINICAL CHEMISTRY

Serum HO-1 is useful to make differential diagnosis of secondary hemophagocytic syndrome from other similar hematological conditions

(2010) Takuya Miyazaki et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Human Heme Oxygenase-1 Deficiency Presenting With Hemolysis, Nephritis, and Asplenia

(2010) Nita Radhakrishnan et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Plasma Heme Oxygenase-1 Concentration Is Elevated in Individuals with Type 2 Diabetes Mellitus

(2010) Wei Bao et al.   PLoS One

Plasma haemoxygenase-1 in coronary artery disease

(2010) Naglaa Idriss et al.   THROMBOSIS AND HAEMOSTASIS

Serum heme oxygenase-1 levels are increased in Parkinson’s disease but not in Alzheimer’s disease

(2009) I. Mateo et al.   ACTA NEUROLOGICA SCANDINAVICA

Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State

(2009) Mustafa Zakkar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Anti-atherogenic effect of statins: role of nitric oxide, peroxynitrite and haem oxygenase-1

(2009) G Heeba et al.   BRITISH JOURNAL OF PHARMACOLOGY

Heme Oxygenase 1 Determines Atherosclerotic Lesion Progression Into a Vulnerable Plaque

(2009) Caroline Cheng et al.   CIRCULATION

Expression of heme oxygenase-1, hypoxia inducible factor-1α, and ubiquitin in peripheral inflammatory cells from patients with coronary heart disease

(2009) Song-Ming Chen et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Serum Bilirubin and Ferritin Levels Link Heme Oxygenase-1 Gene Promoter Polymorphism and Susceptibility to Coronary Artery Disease in Diabetic Patients

(2008) Y.-H. Chen et al.   DIABETES CARE

Pharmacological and Clinical Aspects of Heme Oxygenase

(2008) N. G. Abraham et al.   PHARMACOLOGICAL REVIEWS

Natural heme oxygenase-1 inducers in hepatobiliary function

(2008) Giovanni Li Volti et al.   WORLD JOURNAL OF GASTROENTEROLOGY