Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing

DiGeorge Critical Region 8 (DGCR8) Is a Double-cysteine-ligated Heme Protein

(2011) Ian Barr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex

(2011) Claude M Schofield et al.   Neural Development

Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex

(2011) K. Fenelon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into RNA interference

(2010) Dipali G. Sashital et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Iron and Porphyrin Trafficking in Heme Biogenesis

(2010) Iman J. Schultz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia

(2010) Maria Karayiorgou et al.   NATURE REVIEWS NEUROSCIENCE

Structure of the dimerization domain of DiGeorge Critical Region 8

(2010) Rachel Senturia et al.   PROTEIN SCIENCE

DGCR8 recognizes primary transcripts of microRNAs through highly cooperative binding and formation of higher-order structures

(2010) M. Faller et al.   RNA

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNA biogenesis: there's more than one way to skin a cat

(2008) M FALLER et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

(2008) Kimberly L Stark et al.   NATURE GENETICS

DGCR8-dependent microRNA biogenesis is essential for skin development

(2008) R. Yi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA