Make It, Take It, or Leave It: Heme Metabolism of Parasites

The Use and Abuse of Heme in Apicomplexan Parasites

(2012) Giel G. van Dooren et al.   ANTIOXIDANTS & REDOX SIGNALING

Heme Utilization in theCaenorhabditis elegansHypodermal Cells Is Facilitated by Heme-responsive Gene-2

(2012) Caiyong Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aerobic kinetoplastid flagellate Phytomonas does not require heme for viability

(2012) L. Koreny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heme Uptake by Leishmania amazonensis Is Mediated by the Transmembrane Protein LHR1

(2012) Chau Huynh et al.   PLoS Pathogens

Entamoeba histolyticasecretes two haem-binding proteins to scavenge haem

(2011) Areli Cruz-Castañeda et al.   BIOCHEMICAL JOURNAL

Sequence Evidence for the Presence of Two Tetrapyrrole Pathways in Euglena gracilis

(2011) Luděk Kořený et al.   Genome Biology and Evolution

Tetrapyrrole Synthesis of Photosynthetic Chromerids Is Likely Homologous to the Unusual Pathway of Apicomplexan Parasites

(2011) Luděk Kořený et al.   PLANT CELL

Identification and Phylogenetic Analysis of Heme Synthesis Genes in Trypanosomatids and Their Bacterial Endosymbionts

(2011) João M. P. Alves et al.   PLoS One

Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum

(2011) Ellen Yeh et al.   PLOS BIOLOGY

Giardia lamblia encodes a functional flavohemoglobin

(2010) Steven Rafferty et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis

(2010) Carola Huthmacher et al.   BMC Systems Biology

Ascorbate Peroxidase from Leishmania major Controls the Virulence of Infective Stage of Promastigotes by Regulating Oxidative Stress

(2010) Swati Pal et al.   PLoS One

The complete sequence of the smallest known nuclear genome from the microsporidian Encephalitozoon intestinalis

(2010) Nicolas Corradi et al.   Nature Communications

Evolution of the haem synthetic pathway in kinetoplastid flagellates: An essential pathway that is not essential after all?

(2009) Luděk Kořený et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Knockdown of proteins involved in iron metabolism limits tick reproduction and development

(2009) O. Hajdusek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Heme Biosynthetic Pathway of the Obligate Wolbachia Endosymbiont of Brugia malayi as a Potential Anti-filarial Drug Target

(2009) Bo Wu et al.   PLoS Neglected Tropical Diseases

Heme as a source of iron to Leishmania infantum amastigotes

(2008) Sandra Carvalho et al.   ACTA TROPICA

The novel heme oxygenase-like protein fromPlasmodiumfalciparumconverts heme to bilirubin IXα in the apicoplast

(2008) Ken Okada   FEBS LETTERS

A Haptoglobin-Hemoglobin Receptor Conveys Innate Immunity to Trypanosoma brucei in Humans

(2008) B. Vanhollebeke et al.   SCIENCE

Leishmania spp.: Delta-aminolevulinate-inducible neogenesis of porphyria by genetic complementation of incomplete heme biosynthesis pathway

(2007) Sujoy Dutta et al.   EXPERIMENTAL PARASITOLOGY