Radionuclide imaging and therapy directed towards the tumor microenvironment: a multi-cancer approach for personalized medicine

In vitro and in vivo evaluation of 211At-labeled fibroblast activation protein inhibitor for glioma treatment

(2022) Huan Ma et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Preliminary Clinical Application of RGD-Containing Peptides as PET Radiotracers for Imaging Tumors

(2022) Li Li et al.   Frontiers in Oncology

Pentixafor PET/CT for imaging of chemokine receptor 4 expression in esophageal cancer – a first clinical approach

(2021) Philipp Linde et al.   CANCER IMAGING

An Experimental Study on [125I]I-pHLIP (Var7) for SPECT/CT Imaging of an MDA-MB-231 Triple-Negative Breast Cancer Mouse Model by Targeting the Tumor Microenvironment

(2021) Mingming Yu et al.   Molecular Imaging

The Role of VEGF Receptors as Molecular Target in Nuclear Medicine for Cancer Diagnosis and Combination Therapy

(2021) Katarzyna Masłowska et al.   Cancers

Cancer-Associated Fibroblasts as Players in Cancer Development and Progression and Their Role in Targeted Radionuclide Imaging and Therapy

(2021) Sofia Koustoulidou et al.   Cancers

Targeting the Hypoxic and Acidic Tumor Microenvironment with pH-Sensitive Peptides

(2021) Nayanthara U. Dharmaratne et al.   Cells

Safety of Fibroblast Activation Protein–Targeted Radionuclide Therapy by a Low-Dose Dosimetric Approach Using 177Lu-FAPI04

(2021) Serkan Kuyumcu et al.   CLINICAL NUCLEAR MEDICINE

Endoglin/CD105-Based Imaging of Cancer and Cardiovascular Diseases: A Systematic Review

(2021) Vincent Q. Sier et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Positron Emission Tomography Imaging of Macrophages in Cancer

(2021) Candace C. Parker et al.   Cancers

The Role of Tumor-Stroma Interactions in Drug Resistance Within Tumor Microenvironment

(2021) Yanghong Ni et al.   Frontiers in Cell and Developmental Biology

In vivo preclinical assessment of novel 68Ga-labelled peptides for imaging of tumor associated angiogenesis using positron emission tomography imaging

(2021) Noémi Dénes et al.   APPLIED RADIATION AND ISOTOPES

PSMA radioligand therapy for solid tumors other than prostate cancer: background, opportunities, challenges, and first clinical reports

(2021) M. J. M. Uijen et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Head-to-head intra-individual comparison of biodistribution and tumor uptake of 68Ga-FAPI and 18F-FDG PET/CT in cancer patients

(2021) Frederik L. Giesel et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Molecular Imaging of Angiogenesis in Oncology: Current Preclinical and Clinical Status

(2021) Alexandru Florea et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biokinetics and Dosimetry of [177Lu]Lu-Pentixather

(2021) Heribert Hänscheid et al.   JOURNAL OF NUCLEAR MEDICINE

Synthesis, preclinical evaluation, and a pilot clinical PET imaging study of 68Ga-labeled FAPI dimer

(2021) Liang Zhao et al.   JOURNAL OF NUCLEAR MEDICINE

Feasibility, Biodistribution and Preliminary Dosimetry in Peptide-Targeted Radionuclide Therapy (PTRT) of Diverse Adenocarcinomas using 177Lu-FAP-2286: First-in-Human Results

(2021) Richard P Baum et al.   JOURNAL OF NUCLEAR MEDICINE

Relationship of the standard uptake value of 18F-FDG-PET-CT with tumor-infiltrating lymphocytes in breast tumors measuring ≥ 1 cm

(2021) Soeun Park et al.   Scientific Reports

89Zr-pembrolizumab imaging as a non-invasive approach to assess clinical response to PD-1 blockade in cancer

(2021) I.C. Kok et al.   ANNALS OF ONCOLOGY

Radioligands Targeting Fibroblast Activation Protein (FAP)

(2021) Thomas Lindner et al.   Cancers

Quantification of PD-L1 expression with [18F]BMS-986192 PET/CT in patients with advanced stage non-small-cell lung cancer

(2020) Marc Huisman et al.   JOURNAL OF NUCLEAR MEDICINE

Tumor Microenvironment

(2020) Borros Arneth   Medicina-Lithuania

Relevance of immune cell and tumor microenvironment imaging in the new era of immunotherapy

(2020) Filippo Galli et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Design and development of 99mTc labeled FAPI-tracers for SPECT-imaging and 188Re therapy.

(2020) Thomas Lindner et al.   JOURNAL OF NUCLEAR MEDICINE

Human fibronectin Extra Domain B (ED‐B) as a biomarker for targeted therapy in cancer

(2020) Relinde I.Y. Lieverse et al.   Molecular Oncology

Hypoxia imaging and theranostic potential of [64Cu][Cu(ATSM)] and ionic Cu(II) salts: a review of current evidence and discussion of the retention mechanisms

(2020) Tengzhi Liu et al.   EJNMMI Research

PET Imaging of VEGFR with a Novel 64Cu-Labeled Peptide

(2020) Kuan Hu et al.   ACS Omega

A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling

(2020) Junbin Qian et al.   CELL RESEARCH

Targeting of CD163+ Macrophages in Inflammatory and Malignant Diseases

(2020) Maria K. Skytthe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

FAPI-74 PET/CT Using Either 18F-AlF or Cold-kit 68Ga-labeling: Biodistribution, Radiation Dosimetry and Tumor Delineation in Lung Cancer Patients

(2020) Frederik Giesel et al.   JOURNAL OF NUCLEAR MEDICINE

How and Why Are Cancers Acidic? Carbonic Anhydrase IX and the Homeostatic Control of Tumour Extracellular pH

(2020) Shen-Han Lee et al.   Cancers

High Expression of FAP in Colorectal Cancer Is Associated With Angiogenesis and Immunoregulation Processes

(2020) Mairene Coto-Llerena et al.   Frontiers in Oncology

The tumor microenvironment

(2020) Nicole M. Anderson et al.   CURRENT BIOLOGY

The Role of Translocator Protein TSPO in Hallmarks of Glioblastoma

(2020) Laura-Marie Ammer et al.   Cancers

Radiolabeled fibroblast activation protein inhibitor (FAPI) PET in oncology: has the time come for 18F-fluorodeoxyglucose to think to a well-deserved retirement?

(2020) Priscilla Guglielmo et al.   Clinical and Translational Imaging

Development and Evaluation of an 18F-Radiolabeled Monocyclam Derivative for Imaging CXCR4 Expression

(2019) Diana Brickute et al.   MOLECULAR PHARMACEUTICS

Clinical Translation of [68Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages

(2019) Catarina Xavier et al.   MOLECULAR IMAGING AND BIOLOGY

Development of novel FAP-targeted radiotracers with improved tumor retention

(2019) Anastasia Loktev et al.   JOURNAL OF NUCLEAR MEDICINE

Targeting Tumor Microenvironment for Cancer Therapy

(2019) Catarina Roma-Rodrigues et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

18F-FPPRGD2 PET/CT in patients with metastatic renal cell cancer

(2019) Akira Toriihara et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Imaging tumor acidosis: a survey of the available techniques for mapping in vivo tumor pH

(2019) Annasofia Anemone et al.   CANCER AND METASTASIS REVIEWS

FAPI-PET/CT: Mean intensity of tracer-uptake (SUV) in 28 different kinds of cancer

(2019) Clemens Kratochwil et al.   JOURNAL OF NUCLEAR MEDICINE

Tumor imaging using radiolabelled matrix metalloproteinase-activated anthrax proteins

(2019) Mary-Ann Elvina Xavier et al.   JOURNAL OF NUCLEAR MEDICINE

Noninvasive imaging of tumor progression, metastasis, and fibrosis using a nanobody targeting the extracellular matrix

(2019) Noor Jailkhani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Tumor Microenvironment Innately Modulates Cancer Progression

(2019) Dominique C. Hinshaw et al.   CANCER RESEARCH

Are Integrins Still Practicable Targets for Anti-Cancer Therapy?

(2019) Alday-Parejo et al.   Cancers

Dual-tracer PET of viable tumor volume and hypoxia for identification of necrosis-containing radio-resistant Sub-volumes

(2019) Morten Busk et al.   ACTA ONCOLOGICA

Cancer-associated adipocytes: key players in breast cancer progression

(2019) Qi Wu et al.   Journal of Hematology & Oncology

A 89Zr-HDL PET tracer monitors response to a CSF1R inhibitor

(2019) Christian Mason et al.   JOURNAL OF NUCLEAR MEDICINE

Molecular Imaging Probes Based on Matrix Metalloproteinase Inhibitors (MMPIs)

(2019) Rangasamy et al.   MOLECULES

Theranostics targeting fibroblast activation protein in the tumor stroma: 64Cu and 225Ac labelled FAPI-04 in pancreatic cancer xenograft mouse models

(2019) Tadashi Watabe et al.   JOURNAL OF NUCLEAR MEDICINE

Correlation between maximum standardized uptake values on FDG-PET and microenvironmental factors in patients with clinical stage IA radiologic pure-solid lung adenocarcinoma

(2019) Tomohiro Ichikawa et al.   LUNG CANCER

Comparative evaluation of affibody- and antibody fragments-based CAIX imaging probes in mice bearing renal cell carcinoma xenografts

(2019) Javad Garousi et al.   Scientific Reports

Relaciones entre el factor-1α inducido por hipoxia y los parámetros de la PET/TC con 18F-FDG en el cáncer colorrectal

(2019) Z. Hasbek et al.   Revista Espanola de Medicina Nuclear e Imagen Molecular

Evaluation of an Integrin αvβ3 and Aminopeptidase N Dual-Receptor Targeting Tracer for Breast Cancer Imaging

(2019) Yongkang Gai et al.   MOLECULAR PHARMACEUTICS

The CXCL12-CXCR4/CXCR7 axis as a mechanism of immune resistance in gastrointestinal malignancies

(2019) Sara K. Daniel et al.   SEMINARS IN CANCER BIOLOGY

CAIX-targeting radiotracers for hypoxia imaging in head and neck cancer models

(2019) Fokko J. Huizing et al.   Scientific Reports

Novel use of 177Lu-DOTA-RGD2 in treatment of 68Ga-DOTA-RGD2-avid lesions in papillary thyroid cancer with TENIS

(2018) Ashwin Singh Parihar et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Imaging of Tumor Characteristics and Molecular Pathways With PET: Developments Over the Last Decade Toward Personalized Cancer Therapy

(2018) Loredana Gabriela Marcu et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Development of quinoline based theranostic ligands for the targeting of fibroblast activation protein

(2018) Thomas Lindner et al.   JOURNAL OF NUCLEAR MEDICINE

Pro-tumorigenic roles of fibroblast activation protein in cancer: back to the basics

(2018) Ellen Puré et al.   ONCOGENE

CXCR4-directed theranostics in oncology and inflammation

(2018) Malte Kircher et al.   ANNALS OF NUCLEAR MEDICINE

The prognostic value of [123I]-vascular endothelial growth factor ([123I]-VEGF) in glioma

(2018) Eva Rainer et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Tracking macrophage infiltration in a mouse model of pancreatic cancer with the positron emission tomography tracer [11C]PBR28

(2018) Mirna Perusina Lanfranca et al.   JOURNAL OF SURGICAL RESEARCH

Screening of a Novel Peptide Targeting the Proteoglycan-Like Region of Human Carbonic Anhydrase IX

(2018) Shoaib Rana et al.   Molecular Imaging

Quantitative Imaging of the Hypoxia-Related Marker CAIX in Head and Neck Squamous Cell Carcinoma Xenograft Models

(2018) Fokko J. Huizing et al.   MOLECULAR PHARMACEUTICS

89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer

(2018) Frederike Bensch et al.   NATURE MEDICINE

Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review

(2017) Giuseppe Floresta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

TSPO PET for glioma imaging using the novel ligand 18F-GE-180: first results in patients with glioblastoma

(2017) Nathalie L. Albert et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Radiolabeling of VEGF165 with 99mTc to evaluate VEGFR expression in tumor angiogenesis

(2017) Filippo Galli et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

First Evaluation of PET-Based Human Biodistribution and Dosimetry of 18 F-FAZA, a Tracer for Imaging Tumor Hypoxia

(2017) Annarita Savi et al.   JOURNAL OF NUCLEAR MEDICINE

Targeted radionuclide therapy in combined-modality regimens

(2017) Martin R Gill et al.   LANCET ONCOLOGY

Binding of αvβ3 Integrin-Specific Radiotracers Is Modulated by Both Integrin Expression Level and Activation Status

(2017) Alexandra Andriu et al.   MOLECULAR IMAGING AND BIOLOGY

Applications of pHLIP Technology for Cancer Imaging and Therapy

(2017) Linden C. Wyatt et al.   TRENDS IN BIOTECHNOLOGY

Cancer associated fibroblasts: An essential role in the tumor microenvironment

(2017) Leilei Tao et al.   Oncology Letters

Novel peptide probes to assess the tensional state of fibronectin fibers in cancer

(2017) Simon Arnoldini et al.   Nature Communications

Past, Present, and Future: Development of Theranostic Agents Targeting Carbonic Anhydrase IX

(2017) Joseph Lau et al.   Theranostics

[177Lu]pentixather: Comprehensive Preclinical Characterization of a First CXCR4-directed Endoradiotherapeutic Agent

(2017) Margret Schottelius et al.   Theranostics

Targeting fibronectin for cancer imaging and therapy

(2017) Zheng Han et al.   Journal of Materials Chemistry B

First-in-Man Evaluation of 124I-PGN650: A PET Tracer for Detecting Phosphatidylserine as a Biomarker of the Solid Tumor Microenvironment

(2017) Richard Laforest et al.   Molecular Imaging

Potential Utility of FDG PET-CT as a Non-invasive Tool for Monitoring Local Immune Responses

(2017) Seungho Lee et al.   Journal of Gastric Cancer

AMD3100: A Versatile Platform for CXCR4 Targeting 68Ga-Based Radiopharmaceuticals

(2016) Sophie Poty et al.   BIOCONJUGATE CHEMISTRY

PET Imaging of Extracellular pH in Tumors with 64Cu- and 18F-Labeled pHLIP Peptides: A Structure–Activity Optimization Study

(2016) Dustin Wayne Demoin et al.   BIOCONJUGATE CHEMISTRY

Phase 2 Study of Lutetium 177–Labeled Anti–Carbonic Anhydrase IX Monoclonal Antibody Girentuximab in Patients with Advanced Renal Cell Carcinoma

(2016) Constantijn H.J. Muselaers et al.   EUROPEAN UROLOGY

Radiolabeled Selective Matrix Metalloproteinase 13 (MMP-13) Inhibitors: (Radio)Syntheses and in Vitro and First in Vivo Evaluation

(2016) Verena Hugenberg et al.   JOURNAL OF MEDICINAL CHEMISTRY

Vascular Targeted Radioimmunotherapy for the Treatment of Glioblastoma

(2016) K. Behling et al.   JOURNAL OF NUCLEAR MEDICINE

Comparative Evaluation of Affibody Molecules for Radionuclide Imaging of in Vivo Expression of Carbonic Anhydrase IX

(2016) Javad Garousi et al.   MOLECULAR PHARMACEUTICS

PET Imaging of Carbonic Anhydrase IX Expression of HT-29 Tumor Xenograft Mice with 68Ga-Labeled Benzenesulfonamides

(2016) Joseph Lau et al.   MOLECULAR PHARMACEUTICS

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

(2016) Robert U Svensson et al.   NATURE MEDICINE

Targeting folate receptor alpha for cancer treatment

(2016) Anthony Cheung et al.   Oncotarget

Clinical Application of Radiolabeled RGD Peptides for PET Imaging of Integrin αvβ3

(2016) Haojun Chen et al.   Theranostics

Caged [18F]FDG Glycosylamines for Imaging Acidic Tumor Microenvironments Using Positron Emission Tomography

(2015) Robert R. Flavell et al.   BIOCONJUGATE CHEMISTRY

First-In-Human Study Demonstrating Tumor-Angiogenesis by PET/CT Imaging with68Ga-NODAGA-THERANOST, a High-Affinity Peptidomimetic for αvβ3Integrin Receptor Targeting

(2015) Richard P. Baum et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma

(2015) K. Philipp-Abbrederis et al.   EMBO Molecular Medicine

Pilot prospective evaluation of 18F-FPPRGD2 PET/CT in patients with cervical and ovarian cancer

(2015) Ryogo Minamimoto et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Is carbonic anhydrase IX a validated target for molecular imaging of cancer and hypoxia?

(2015) Jianbo Li et al.   Future Oncology

γ-Tilmanocept, a New Radiopharmaceutical Tracer for Cancer Sentinel Lymph Nodes, Binds to the Mannose Receptor (CD206)

(2015) Abul K. Azad et al.   JOURNAL OF IMMUNOLOGY

PET Imaging of Macrophage Mannose Receptor-Expressing Macrophages in Tumor Stroma Using 18F-Radiolabeled Camelid Single-Domain Antibody Fragments

(2015) A. Blykers et al.   JOURNAL OF NUCLEAR MEDICINE

PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles

(2015) C. Perez-Medina et al.   JOURNAL OF NUCLEAR MEDICINE

First-in-Human Experience of CXCR4-Directed Endoradiotherapy with 177Lu- and 90Y-Labeled Pentixather in Advanced-Stage Multiple Myeloma with Extensive Intra- and Extramedullary Disease

(2015) K. Herrmann et al.   JOURNAL OF NUCLEAR MEDICINE

Biodistribution and Radiation Dosimetry for the Chemokine Receptor CXCR4-Targeting Probe 68Ga-Pentixafor

(2015) K. Herrmann et al.   JOURNAL OF NUCLEAR MEDICINE

Genetic instability in the tumor microenvironment: a new look at an old neighbor

(2015) Antonio Palumbo et al.   Molecular Cancer

Fibroblast activation protein and its prognostic significance in correlation with vascular endothelial growth factor in pancreatic adenocarcinoma

(2015) DIMITRIOS PATSOURAS et al.   Molecular Medicine Reports

Radiofluorinated probe for PET imaging of fatty acid binding protein 4 in cancer

(2015) Takashi Temma et al.   NUCLEAR MEDICINE AND BIOLOGY

F-18 Fluoromisonidazole for Imaging Tumor Hypoxia: Imaging the Microenvironment for Personalized Cancer Therapy

(2015) Joseph G. Rajendran et al.   SEMINARS IN NUCLEAR MEDICINE

Tenascin-C: Exploitation and collateral damage in cancer management

(2015) Caroline Spenlé et al.   Cell Adhesion & Migration

Sulfonamide derivative targeting carbonic anhydrase IX as a nuclear imaging probe for colorectal cancer detection in vivo

(2015) Siao-Syun Guan et al.   Oncotarget

Prospective Study of 68Ga-NOTA-NFB: Radiation Dosimetry in Healthy Volunteers and First Application in Glioma Patients

(2015) Zhe Wang et al.   Theranostics

Fibroblast Activation Protein Overexpression and Clinical Implications in Solid Tumors: A Meta-Analysis

(2015) Fang Liu et al.   PLoS One

New radiotracers for imaging of vascular targets in angiogenesis-related diseases

(2014) Hao Hong et al.   ADVANCED DRUG DELIVERY REVIEWS

Imaging tumour hypoxia with positron emission tomography

(2014) I N Fleming et al.   BRITISH JOURNAL OF CANCER

Radioimmunotherapy with Tenarad, a 131I-labelled antibody fragment targeting the extra-domain A1 of tenascin-C, in patients with refractory Hodgkin's lymphoma

(2014) Luigi Aloj et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Imaging of CAIX-expressing xenografts in vivo using 99mTc-HEHEHE-ZCAIX:1 Affibody molecule

(2014) HADIS HONARVAR et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

2-deoxy-2-[18F]fluoro-d-mannose positron emission tomography imaging in atherosclerosis

(2014) Nobuhiro Tahara et al.   NATURE MEDICINE

Bridged cyclams as imaging agents for chemokine receptor 4 (CXCR4)

(2014) Lauren E. Woodard et al.   NUCLEAR MEDICINE AND BIOLOGY

Development of a Radioiodinated Triazolopyrimidine Probe for Nuclear Medical Imaging of Fatty Acid Binding Protein 4

(2014) Kantaro Nishigori et al.   PLoS One

Longitudinal PET Imaging of Muscular Inflammation Using 18F-DPA-714 and 18F-Alfatide II and Differentiation with Tumors

(2014) Chenxi Wu et al.   Theranostics

Is Cancer a Metabolic Disease?

(2013) Hilary A. Coller   AMERICAN JOURNAL OF PATHOLOGY

99mTc-labeled monomeric and dimeric NGR peptides for SPECT imaging of CD13 receptor in tumor-bearing mice

(2013) Wenhui Ma et al.   AMINO ACIDS

Imaging Tumor Hypoxia to Advance Radiation Oncology

(2013) Chen-Ting Lee et al.   ANTIOXIDANTS & REDOX SIGNALING

Acidic extracellular microenvironment and cancer

(2013) Yasumasa Kato et al.   Cancer Cell International

Indium-111–labeled Girentuximab ImmunoSPECT as a Diagnostic Tool in Clear Cell Renal Cell Carcinoma

(2013) Constantijn H.J. Muselaers et al.   EUROPEAN UROLOGY

Application of Monoclonal Antibody G250 Recognizing Carbonic Anhydrase IX in Renal Cell Carcinoma

(2013) Jeannette Oosterwijk-Wakka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Design, Synthesis, and Initial Evaluation of a High Affinity Positron Emission Tomography Probe for Imaging Matrix Metalloproteinases 2 and 9

(2013) Svetlana V. Selivanova et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Preliminary Evaluation in Tumor Bearing Mice of New 18F-Labeled Arylsulfone Matrix Metalloproteinase Inhibitors as Tracers for Positron Emission Tomography

(2013) Francesca Casalini et al.   JOURNAL OF MEDICINAL CHEMISTRY

In Vitro and In Vivo Characterization of 2-Deoxy-2-18F-Fluoro-D-Mannose as a Tumor-Imaging Agent for PET

(2013) S. Furumoto et al.   JOURNAL OF NUCLEAR MEDICINE

Development of an Oxygen-Sensitive Degradable Peptide Probe for the Imaging of Hypoxia-Inducible Factor-1-Active Regions in Tumors

(2013) Masashi Ueda et al.   MOLECULAR IMAGING AND BIOLOGY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

[99mTc(CO)3]-Radiolabeled Bevacizumab: In vitro and in vivo Evaluation in a Melanoma Model

(2013) Ximena Camacho et al.   ONCOLOGY

Fatty Acid Synthase Is a Key Target in Multiple Essential Tumor Functions of Prostate Cancer: Uptake of Radiolabeled Acetate as a Predictor of the Targeted Therapy Outcome

(2013) Yukie Yoshii et al.   PLoS One

Radretumab Radioimmunotherapy in Patients with Brain Metastasis: A 124I-L19SIP Dosimetric PET Study

(2013) G. L. Poli et al.   Cancer Immunology Research

Prospects in Folate Receptor-Targeted Radionuclide Therapy

(2013) Cristina Müller et al.   Frontiers in Oncology

Efficient 18F-Labeling of Large 37-Amino-Acid pHLIP Peptide Analogues and Their Biological Evaluation

(2012) Pierre Daumar et al.   BIOCONJUGATE CHEMISTRY

PET imaging of tumor associated macrophages using mannose coated 64Cu liposomes

(2012) Landon W. Locke et al.   BIOMATERIALS

Nanobody-Based Targeting of the Macrophage Mannose Receptor for EffectiveIn VivoImaging of Tumor-Associated Macrophages

(2012) Kiavash Movahedi et al.   CANCER RESEARCH

Synthesis of BMS-309403-Related Compounds, Including [14C]BMS-309403, a Radioligand for Adipocyte Fatty Acid Binding Protein

(2012) Toshihiko Okada et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Radiolabelled RGD peptides for imaging and therapy

(2012) F. C. Gaertner et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Development of -N4-NIM for Molecular Imaging of Tumor Hypoxia

(2012) Mohammad S. Ali et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Positron Emission Tomography/Computed Tomography Identification of Clear Cell Renal Cell Carcinoma: Results From the REDECT Trial

(2012) Chaitanya R. Divgi et al.   JOURNAL OF CLINICAL ONCOLOGY

Synthesis and SAR of Novel Re/99mTc-Labeled Benzenesulfonamide Carbonic Anhydrase IX Inhibitors for Molecular Imaging of Tumor Hypoxia

(2012) Genliang Lu et al.   JOURNAL OF MEDICINAL CHEMISTRY

PET of Hypoxia: Current and Future Perspectives

(2012) S. Carlin et al.   JOURNAL OF NUCLEAR MEDICINE

Radioiodinated Phenylalkyl Malonic Acid Derivatives as pH-Sensitive SPECT Tracers

(2012) Matthias Bauwens et al.   PLoS One

Synthesis of 6-[18F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18kDa with PET

(2011) Annelaure Damont et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

[18F]GE-180: A novel fluorine-18 labelled PET tracer for imaging Translocator protein 18kDa (TSPO)

(2011) Harry Wadsworth et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

TRAP, a Powerful and Versatile Framework for Gallium-68 Radiopharmaceuticals

(2011) Johannes Notni et al.   CHEMISTRY-A EUROPEAN JOURNAL

A New Generation of Radiofluorinated Pyrimidine-2,4,6-triones as MMP-Targeted Radiotracers for Positron Emission Tomography

(2011) Daniela Schrigten et al.   JOURNAL OF MEDICINAL CHEMISTRY

Radiotracers for different angiogenesis receptors in a melanoma model

(2011) Érica A. Oliveira et al.   MELANOMA RESEARCH

A folate receptor beta-specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibody-dependent cell-mediated cytotoxicity

(2011) Yang Feng et al.   ARTHRITIS RESEARCH & THERAPY

Fibronectins, Their Fibrillogenesis, and In Vivo Functions

(2011) J. E. Schwarzbauer et al.   Cold Spring Harbor Perspectives in Biology

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Radionuclide imaging of perfusion and hypoxia

(2010) George Laking et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Effects of the Antifolates Pemetrexed and CB3717 on the Tissue Distribution of99mTc-EC20 in Xenografted and Syngeneic Tumor-Bearing Mice†

(2010) Cristina Müller et al.   MOLECULAR PHARMACEUTICS

Radiolabeled Cyclic RGD Peptides as Integrin αvβ3-Targeted Radiotracers: Maximizing Binding Affinity via Bivalency

(2009) Shuang Liu   BIOCONJUGATE CHEMISTRY

64Cu-AMD3100—A novel imaging agent for targeting chemokine receptor CXCR4

(2009) Orit Jacobson et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Folate Receptor   Is Expressed by Tumor-Associated Macrophages and Constitutes a Marker for M2 Anti-inflammatory/Regulatory Macrophages

(2009) A. Puig-Kroger et al.   CANCER RESEARCH

Radiobiological effects of hypoxia-dependent uptake of 64Cu-ATSM: enhanced DNA damage and cytotoxicity in hypoxic cells

(2009) Amanda J. Weeks et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Imaging of HIF-1-Active Tumor Hypoxia Using a Protein Effectively Delivered to and Specifically Stabilized in HIF-1-Active Tumor Cells

(2009) T. Kudo et al.   JOURNAL OF NUCLEAR MEDICINE

Tumor Hypoxia Detected by Positron Emission Tomography with 60Cu-ATSM as a Predictor of Response and Survival in Patients Undergoing Neoadjuvant Chemoradiotherapy for Rectal Carcinoma: A Pilot Study

(2008) David W. Dietz et al.   DISEASES OF THE COLON & RECTUM

Specific imaging of VEGF-A expression with radiolabeled anti-VEGF monoclonal antibody

(2008) Thamar H. Stollman et al.   INTERNATIONAL JOURNAL OF CANCER