Empagliflozin attenuates cardiac microvascular ischemia/reperfusion injury through improving mitochondrial homeostasis
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Title
Empagliflozin attenuates cardiac microvascular ischemia/reperfusion injury through improving mitochondrial homeostasis
Authors
Keywords
-
Journal
Cardiovascular Diabetology
Volume 21, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-06-16
DOI
10.1186/s12933-022-01532-6
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Note: Only part of the references are listed.- Empagliflozin Alleviates Left Ventricle Hypertrophy in High-Fat-Fed Mice by Modulating Renin Angiotensin Pathway
- (2022) Juliana Cordovil Cotrin et al. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
- DNA-PKcs interacts with and phosphorylates Fis1 to induce mitochondrial fragmentation in tubular cells during acute kidney injury
- (2022) Shiyuan Wang et al. Science Signaling
- Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE(-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis
- (2021) Narjes Nasiri-Ansari et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Function and regulation of the divisome for mitochondrial fission
- (2021) Felix Kraus et al. NATURE
- Mitochondrial contributions to vascular endothelial dysfunction, arterial stiffness, and cardiovascular diseases
- (2021) Danielle L. Kirkman et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Angiotensin II-induced upregulation of SGLT1 and 2 contributes to human microparticle‐stimulated endothelial senescence and dysfunction: protective effect of gliflozins
- (2021) Sin-Hee Park et al. Cardiovascular Diabetology
- Empagliflozin in Patients With Heart Failure, Reduced Ejection Fraction, and Volume Overload
- (2021) Milton Packer et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- A PKD-MFF signaling axis couples mitochondrial fission to mitotic progression
- (2021) Evanthia Pangou et al. Cell Reports
- Empagliflozin in Heart Failure with a Preserved Ejection Fraction
- (2021) Stefan D. Anker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Empagliflozin maintains capillarization and improves cardiac function in a murine model of left ventricular pressure overload
- (2021) Masaaki Nakao et al. Scientific Reports
- Protective effect of HINT2 on mitochondrial function via repressing MCU complex activation attenuates cardiac microvascular ischemia–reperfusion injury
- (2021) Su Li et al. BASIC RESEARCH IN CARDIOLOGY
- Empagliflozin reduces oxidative stress through inhibition of the novel inflammation/NHE/[Na+]c/ROS-pathway in human endothelial cells
- (2021) Laween Uthman et al. BIOMEDICINE & PHARMACOTHERAPY
- Empagliflozin Relaxes Resistance Mesenteric Arteries by Stimulating Multiple Smooth Muscle Cell Voltage-Gated K+ (KV) Channels
- (2021) Ahasanul Hasan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Green Tea Extract Concurrent with an Oral Nutritional Supplement Acutely Enhances Muscle Microvascular Blood Flow without Altering Leg Glucose Uptake in Healthy Older Adults
- (2021) Ushnah S. U. Din et al. Nutrients
- Sodium–Glucose Co-Transporter 2 Inhibition With Empagliflozin Improves Cardiac Function After Cardiac Arrest in Rats by Enhancing Mitochondrial Energy Metabolism
- (2021) Yunke Tan et al. Frontiers in Pharmacology
- Empagliflozin Induces White Adipocyte Browning and Modulates Mitochondrial Dynamics in KK Cg-Ay/J Mice and Mouse Adipocytes
- (2021) Linxin Xu et al. Frontiers in Physiology
- DNA-PKcs promotes cardiac ischemia reperfusion injury through mitigating BI-1-governed mitochondrial homeostasis
- (2020) Hao Zhou et al. BASIC RESEARCH IN CARDIOLOGY
- New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury
- (2020) Jin Wang et al. ANGIOGENESIS
- Exendin‐4, a GLP‐1 receptor agonist regulates retinal capillary tone and restores microvascular patency after ischaemia–reperfusion injury
- (2020) Ruyi Zhai et al. BRITISH JOURNAL OF PHARMACOLOGY
- Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation
- (2020) Detmar Kolijn et al. CARDIOVASCULAR RESEARCH
- Comparative Effectiveness of Glucose-Lowering Drugs for Type 2 Diabetes
- (2020) Apostolos Tsapas et al. ANNALS OF INTERNAL MEDICINE
- Empagliflozin alleviated mitochondrial fission via decreasing PGAM5.
- (2020) Xiangyang Liu et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Mitochondrial quality control in cardiac microvascular ischemia-reperfusion injury: New insights into the mechanisms and therapeutic potentials
- (2020) Jin Wang et al. PHARMACOLOGICAL RESEARCH
- Regulation of Mammalian Mitochondrial Dynamics: Opportunities and Challenges
- (2020) Rong Yu et al. Frontiers in Endocrinology
- Empagliflozin dilates the rabbit aorta by activating PKG and voltage-dependent K+ channels
- (2020) Mi Seon Seo et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Effect of Empagliflozin on Cardiovascular and Renal Outcomes in Patients With Heart Failure by Baseline Diabetes Status
- (2020) Stefan D. Anker et al. CIRCULATION
- SERCA Overexpression Improves Mitochondrial Quality Control and Attenuates Cardiac Microvascular Ischemia-Reperfusion Injury
- (2020) Ying Tan et al. Molecular Therapy-Nucleic Acids
- Discovery of new therapeutic redox targets for cardioprotection against ischemia/reperfusion injury and heart failure
- (2020) Andreas Daiber et al. FREE RADICAL BIOLOGY AND MEDICINE
- Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury
- (2019) Sean M. Davidson et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- SGLT2 inhibition with empagliflozin attenuates myocardial oxidative stress and fibrosis in diabetic mice heart
- (2019) Chenguang Li et al. Cardiovascular Diabetology
- SGLT2 inhibition with empagliflozin improves coronary microvascular function and cardiac contractility in prediabetic ob/ob−/− mice
- (2019) Damilola D. Adingupu et al. Cardiovascular Diabetology
- Angiotensin II‐induced redox‐sensitive SGLT1 and 2 expression promotes high glucose‐induced endothelial cell senescence
- (2019) Sonia Khemais‐Benkhiat et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Empagliflozin restores the integrity of the endothelial glycocalyx in vitro
- (2019) Scott Cooper et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- DNA-PK as an Emerging Therapeutic Target in Cancer
- (2019) Ismail S. Mohiuddin et al. Frontiers in Oncology
- Tanshinone IIA attenuates cardiac microvascular ischemia-reperfusion injury via regulating the SIRT1-PGC1α-mitochondrial apoptosis pathway
- (2019) Jiankai Zhong et al. CELL STRESS & CHAPERONES
- Empagliflozin Protects HK-2 Cells from High Glucose-Mediated Injuries via a Mitochondrial Mechanism
- (2019) Wen-Chin Lee et al. Cells
- Empagliflozin, a sodium glucose co-transporter-2 inhibitor, alleviates atrial remodeling and improves mitochondrial function in high-fat diet/streptozotocin-induced diabetic rats
- (2019) Qingmiao Shao et al. Cardiovascular Diabetology
- Empagliflozin attenuates ischemia and reperfusion injury through LKB1/AMPK signaling pathway
- (2019) Qingguo Lu et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- BI1 is associated with microvascular protection in cardiac ischemia reperfusion injury via repressing Syk–Nox2–Drp1-mitochondrial fission pathways
- (2018) Hao Zhou et al. ANGIOGENESIS
- NR4A1 aggravates the cardiac microvascular ischemia reperfusion injury through suppressing FUNDC1-mediated mitophagy and promoting Mff-required mitochondrial fission by CK2α
- (2018) Hao Zhou et al. BASIC RESEARCH IN CARDIOLOGY
- Mitochondrial dysfunctions, endothelial progenitor cells and diabetic retinopathy
- (2018) Yan Shao et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- HDAC1 localizes to the mitochondria of cardiac myocytes and contributes to early cardiac reperfusion injury
- (2018) Daniel J. Herr et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- The uremic toxin hippurate promotes endothelial dysfunction via the activation of Drp1-mediated mitochondrial fission
- (2018) Mengjie Huang et al. Redox Biology
- DUSP1 alleviates cardiac ischemia/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways
- (2018) Qinhua Jin et al. Redox Biology
- Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission
- (2018) Hao Zhou et al. Redox Biology
- Structural basis of mitochondrial receptor binding and constriction by DRP1
- (2018) Raghav Kalia et al. NATURE
- Mitochondrial dynamics: Biological roles, molecular machinery, and related diseases
- (2018) Ayman W. El-Hattab et al. MOLECULAR GENETICS AND METABOLISM
- Ferulic acid (FA) abrogates γ-radiation induced oxidative stress and DNA damage by up-regulating nuclear translocation of Nrf2 and activation of NHEJ pathway
- (2017) Ujjal Das et al. FREE RADICAL RESEARCH
- Drp1-Dependent Mitochondrial Fission Plays Critical Roles in Physiological and Pathological Progresses in Mammals
- (2017) Chenxia Hu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission-VDAC1-HK2-mPTP-mitophagy axis
- (2017) Hao Zhou et al. JOURNAL OF PINEAL RESEARCH
- Mff‐Dependent Mitochondrial Fission Contributes to the Pathogenesis of Cardiac Microvasculature Ischemia/Reperfusion Injury via Induction of mROS‐Mediated Cardiolipin Oxidation and HK2/VDAC1 Disassociation‐Involved mPTP Opening
- (2017) Hao Zhou et al. Journal of the American Heart Association
- Sildenafil Protects against Myocardial Ischemia-Reperfusion Injury Following Cardiac Arrest in a Porcine Model: Possible Role of the Renin-Angiotensin System
- (2015) Guoxing Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
- (2015) Bernard Zinman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mitochondria and Endothelial Function
- (2013) Matthew A. Kluge et al. CIRCULATION RESEARCH
- Effects of Fluid Shear Stress on Expression of Smac/DIABLO in Human Umbilical Vein Endothelial Cells
- (2013) Feng Zhang et al. CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
- Endothelial mitochondria—less respiration, more integration
- (2012) Lukas N. Groschner et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- New insights into the roles of ATM and DNA-PKcs in the cellular response to oxidative stress
- (2011) Benjamin P.C. Chen et al. CANCER LETTERS
- Modeling of biopterin-dependent pathways of eNOS for nitric oxide and superoxide production
- (2011) Saptarshi Kar et al. FREE RADICAL BIOLOGY AND MEDICINE
- Pathogenesis of Myocardial Ischemia-Reperfusion Injury and Rationale for Therapy
- (2010) Aslan T. Turer et al. AMERICAN JOURNAL OF CARDIOLOGY
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