Mitochondrial contributions to vascular endothelial dysfunction, arterial stiffness, and cardiovascular diseases
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mitochondrial contributions to vascular endothelial dysfunction, arterial stiffness, and cardiovascular diseases
Authors
Keywords
-
Journal
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Volume 320, Issue 5, Pages H2080-H2100
Publisher
American Physiological Society
Online
2021-04-09
DOI
10.1152/ajpheart.00917.2020
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Vasodilatory and vascular mitochondrial respiratory function with advancing age: Evidence of a free radically-mediated link in the human vasculature
- (2020) Soung Hun Park et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Lactate accelerates vascular calcification through NR4A1-regulated mitochondrial fission and BNIP3-related mitophagy
- (2020) Yi Zhu et al. APOPTOSIS
- Effects of resveratrol or estradiol on post-exercise endothelial function in estrogen-deficient postmenopausal women
- (2020) Cemal Ozemek et al. JOURNAL OF APPLIED PHYSIOLOGY
- Effects of Elamipretide on Left Ventricular Function in Patients with Heart Failure with Reduced Ejection Fraction: The PROGRESS-HF Phase 2 Trial
- (2020) Javed Butler et al. JOURNAL OF CARDIAC FAILURE
- Supplemental Vitamins and Minerals for Cardiovascular Disease Prevention and Treatment
- (2020) David Perez Ingles et al. Current Cardiology Reports
- Short-term time-restricted feeding is safe and feasible in non-obese healthy midlife and older adults
- (2020) Christopher R. Martens et al. GeroScience
- Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects
- (2020) Tamas Kiss et al. GeroScience
- Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Diseases?
- (2020) Alexis Diaz-Vegas et al. ENDOCRINE REVIEWS
- Accelerated cerebral vascular injury in diabetes is associated with vascular smooth muscle cell dysfunction
- (2020) Ya Guo et al. GeroScience
- Acute mitochondrial antioxidant intake improves endothelial function, antioxidant enzyme activity, and exercise tolerance in patients with peripheral artery disease
- (2020) Song-Young Park et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Targeting mitochondrial fitness as a strategy for healthy vascular aging
- (2020) Matthew J. Rossman et al. CLINICAL SCIENCE
- High rate of hypertension in patients with m.3243A>G MELAS mutations and POLG variants
- (2020) Andrew D. Pauls et al. MITOCHONDRION
- Lifelong voluntary aerobic exercise prevents age‐ and Western diet‐induced vascular dysfunction, mitochondrial oxidative stress, and inflammation in mice
- (2020) Rachel A. Gioscia‐Ryan et al. JOURNAL OF PHYSIOLOGY-LONDON
- The contribution of uncoupling protein 2 to mitochondrial Ca2+ homeostasis - a short revisit
- (2020) Zhanat Koshenov et al. MITOCHONDRION
- Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association
- (2019) Emelia J. Benjamin et al. CIRCULATION
- P66Shc and vascular endothelial function
- (2019) Santosh Kumar BIOSCIENCE REPORTS
- Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice
- (2019) Stefano Tarantini et al. Redox Biology
- Reconstitution of autophagy ameliorates vascular function and arterial stiffening in spontaneously hypertensive rats
- (2019) Cameron G. McCarthy et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Hypertension Exacerbates Cerebrovascular Oxidative Stress Induced by Mild Traumatic Brain Injury: Protective Effects of the Mitochondria-Targeted Antioxidative Peptide SS-31
- (2019) Andras Czigler et al. JOURNAL OF NEUROTRAUMA
- NADPH oxidase 4 mediates the protective effects of physical activity against obesity-induced vascular dysfunction
- (2019) Heike Brendel et al. CARDIOVASCULAR RESEARCH
- Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis
- (2019) Daniel J. Tyrrell et al. CIRCULATION RESEARCH
- Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress
- (2019) Anna E. Dikalova et al. CIRCULATION RESEARCH
- Stimulation of autophagy improves vascular function in the mesenteric arteries of type 2 diabetic mice
- (2019) Soo‐Kyoung Choi et al. EXPERIMENTAL PHYSIOLOGY
- Projected U.S. State-Level Prevalence of Adult Obesity and Severe Obesity
- (2019) Zachary J. Ward et al. NEW ENGLAND JOURNAL OF MEDICINE
- Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice
- (2018) Stefano Tarantini et al. AGING CELL
- Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice
- (2018) Kirsty Foote et al. AGING CELL
- Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline
- (2018) Claudia Schwarz et al. Aging-US
- Overexpression of hexokinase 2 reduces mitochondrial calcium overload in coronary endothelial cells of type 2 diabetic mice
- (2018) Minglin Pan et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Mitochondrial uncoupling, ROS generation and cardioprotection
- (2018) Susana Cadenas BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR
- (2018) Jun Yoshino et al. Cell Metabolism
- Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older AdultsNovelty and Significance
- (2018) Matthew J. Rossman et al. HYPERTENSION
- Vascular Aging
- (2018) Douglas R. Seals et al. JOURNAL OF APPLIED PHYSIOLOGY
- Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice
- (2018) Rachel A. Gioscia-Ryan et al. JOURNAL OF APPLIED PHYSIOLOGY
- The role of inorganic nitrate and nitrite in cardiovascular disease risk factors: a systematic review and meta-analysis of human evidence
- (2018) Jacklyn K Jackson et al. NUTRITION REVIEWS
- Spermidine in health and disease
- (2018) Frank Madeo et al. SCIENCE
- Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
- (2018) Christopher R. Martens et al. Nature Communications
- Endothelial function and dysfunction: Impact of metformin
- (2018) Asma Nafisa et al. PHARMACOLOGY & THERAPEUTICS
- The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial
- (2018) Miranka Wirth et al. CORTEX
- Rapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis
- (2018) Gabriele Civiletto et al. EMBO Molecular Medicine
- Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice
- (2018) Matthew D. Campbell et al. FREE RADICAL BIOLOGY AND MEDICINE
- [Na+] Increases in Body Fluids Sensed by Central Nax Induce Sympathetically Mediated Blood Pressure Elevations via H+-Dependent Activation of ASIC1a
- (2018) Kengo Nomura et al. NEURON
- Vascular Adaptations to Habitual Exercise in Older Adults
- (2017) Kerrie L. Moreau et al. EXERCISE AND SPORT SCIENCES REVIEWS
- PGC-1α (Peroxisome Proliferator–Activated Receptor γ Coactivator 1-α) Overexpression in Coronary Artery Disease Recruits NO and Hydrogen Peroxide During Flow-Mediated Dilation and Protects Against Increased Intraluminal PressureNovelty and Significance
- (2017) Andrew O. Kadlec et al. HYPERTENSION
- New Insights into the Role of Inflammation in the Pathogenesis of Atherosclerosis
- (2017) Meng-Yu Wu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015
- (2017) Gregory A. Roth et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Resveratrol Improves Vascular Function and Mitochondrial Number but Not Glucose Metabolism in Older Adults
- (2017) Rena M Pollack et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Roles of NADPH oxidase and mitochondria in flow-induced vasodilation of human adipose arterioles: ROS-induced ROS release in coronary artery disease
- (2017) Natalya S. Zinkevich et al. MICROCIRCULATION
- mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1
- (2017) Masahiro Morita et al. MOLECULAR CELL
- AMPK: guardian of metabolism and mitochondrial homeostasis
- (2017) Sébastien Herzig et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Uncoupling Protein 2: A Key Player and a Potential Therapeutic Target in Vascular Diseases
- (2017) Giorgia Pierelli et al. Oxidative Medicine and Cellular Longevity
- Mitochondria and Reactive Oxygen Species Contribute to Neurogenic Hypertension
- (2017) Samuel H.H. Chan et al. PHYSIOLOGY
- Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease
- (2017) Filippo Scialò et al. Frontiers in Physiology
- Inflammatory Markers for Arterial Stiffness in Cardiovascular Diseases
- (2017) Ioana Mozos et al. Frontiers in Immunology
- Transcriptome analysis of inflammation-related gene expression in endothelial cells activated by complement MASP-1
- (2017) Endre Schwaner et al. Scientific Reports
- Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice
- (2016) Natalie E. de Picciotto et al. AGING CELL
- Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways
- (2016) Lisa A. Lesniewski et al. AGING CELL
- Oral trehalose supplementation improves resistance artery endothelial function in healthy middle-aged and older adults
- (2016) Rachelle E. Kaplon et al. Aging-US
- Voluntary aerobic exercise increases arterial resilience and mitochondrial health with aging in mice
- (2016) Rachel A. Gioscia-Ryan et al. Aging-US
- Restoration of autophagy in endothelial cells from patients with diabetes mellitus improves nitric oxide signaling
- (2016) Jessica L. Fetterman et al. ATHEROSCLEROSIS
- Mitochondrial signaling in the vascular endothelium: beyond reactive oxygen species
- (2016) Andrew O. Kadlec et al. BASIC RESEARCH IN CARDIOLOGY
- Vascular mTOR-dependent mechanisms linking the control of aging to Alzheimer's disease
- (2016) Veronica Galvan et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Measurement of Reactive Oxygen Species, Reactive Nitrogen Species, and Redox-Dependent Signaling in the Cardiovascular System
- (2016) Kathy K. Griendling et al. CIRCULATION RESEARCH
- Inflammation, Endothelial Dysfunction and Arterial Stiffness as Therapeutic Targets in Cardiovascular Medicine
- (2016) Vittoriano Della Corte et al. CURRENT PHARMACEUTICAL DESIGN
- Metformin Suppresses Diabetes-Accelerated Atherosclerosis via the Inhibition of Drp1-Mediated Mitochondrial Fission
- (2016) Qilong Wang et al. DIABETES
- Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autophagy, in the liver of middle-aged mice
- (2016) V. Martínez-Cisuelo et al. EXPERIMENTAL GERONTOLOGY
- Diluted serum from calorie-restricted animals promotes mitochondrial β-cell adaptations and protect against glucolipotoxicity
- (2016) Fernanda M. Cerqueira et al. FEBS Journal
- Effects of sodium nitrite supplementation on vascular function and related small metabolite signatures in middle-aged and older adults
- (2016) Allison E. DeVan et al. JOURNAL OF APPLIED PHYSIOLOGY
- Mitochondrial calcium homeostasis: Implications for neurovascular and neurometabolic coupling
- (2016) Sridhar S Kannurpatti JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- p66Shc regulates renal vascular tone in hypertension-induced nephropathy
- (2016) Bradley Miller et al. JOURNAL OF CLINICAL INVESTIGATION
- Practical alternatives to chronic caloric restriction for optimizing vascular function with ageing
- (2016) Christopher R. Martens et al. JOURNAL OF PHYSIOLOGY-LONDON
- Cardioprotection and lifespan extension by the natural polyamine spermidine
- (2016) Tobias Eisenberg et al. NATURE MEDICINE
- Endothelial AMPK activation induces mitochondrial biogenesis and stress adaptation via eNOS-dependent mTORC1 signaling
- (2016) Chunying Li et al. NITRIC OXIDE-BIOLOGY AND CHEMISTRY
- Arterial stiffness and sedentary lifestyle: Role of oxidative stress
- (2016) Gianfranco Lessiani et al. VASCULAR PHARMACOLOGY
- Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study
- (2015) Shanti Velmurugan et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Dynamics of enhanced mitochondrial respiration in female compared with male rat cerebral arteries
- (2015) Ibolya Rutkai et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Sirtuin regulation in aging and injury
- (2015) Ninu Poulose et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mitochondria DNA mutations cause sex-dependent development of hypertension and alterations in cardiovascular function
- (2015) Mark J. Golob et al. JOURNAL OF BIOMECHANICS
- Vascular nitric oxide: Beyond eNOS
- (2015) Yingzi Zhao et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Beneficial effects of exercise on age-related mitochondrial dysfunction and oxidative stress in skeletal muscle
- (2015) Anna-Maria Joseph et al. JOURNAL OF PHYSIOLOGY-LONDON
- Mitochondrial mechanisms of endothelial dysfunction
- (2015) Adam Szewczyk et al. Pharmacological Reports
- Mild caloric restriction reduces blood pressure and activates endothelial AMPK-PI3K-Akt-eNOS pathway in obese Zucker rats
- (2015) C.F. García-Prieto et al. VASCULAR PHARMACOLOGY
- AMP-activated protein kinase controls exercise training- and AICAR-induced increases in SIRT3 and MnSOD
- (2015) Josef Brandauer et al. Frontiers in Physiology
- The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice
- (2014) Lindsey B. Gano et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Cardiac, skeletal, and smooth muscle mitochondrial respiration: are all mitochondria created equal?
- (2014) Song-Young Park et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Targeting mitochondria to restore failed adaptation to exercise in diabetes
- (2014) Kate Geary et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Sirtuin 3 Deficiency Is Associated with Inhibited Mitochondrial Function and Pulmonary Arterial Hypertension in Rodents and Humans
- (2014) Roxane Paulin et al. Cell Metabolism
- Mitochondrial quality control and age-associated arterial stiffening
- (2014) Thomas J. LaRocca et al. EXPERIMENTAL GERONTOLOGY
- Chronic aerobic exercise training attenuates aortic stiffening and endothelial dysfunction through preserving aortic mitochondrial function in aged rats
- (2014) Qi Gu et al. EXPERIMENTAL GERONTOLOGY
- Mitochondrial ultrastructure and markers of dynamics in hepatocytes from aged, calorie restricted mice fed with different dietary fats
- (2014) Husam Khraiwesh et al. EXPERIMENTAL GERONTOLOGY
- Enhanced age-dependent cerebrovascular dysfunction is mediated by adaptor protein p66Shc
- (2014) Yi Shi et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Edward F. Adolph Distinguished Lecture: The remarkable anti-aging effects of aerobic exercise on systemic arteries
- (2014) Douglas R. Seals JOURNAL OF APPLIED PHYSIOLOGY
- Saxagliptin Restores Vascular Mitochondrial Exercise Response in the Goto-Kakizaki Rat
- (2014) Amy C. Keller et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice
- (2014) Rachel A. Gioscia-Ryan et al. JOURNAL OF PHYSIOLOGY-LONDON
- Effects of Exercise Modalities on Arterial Stiffness and Wave Reflection: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- (2014) Ammar W. Ashor et al. PLoS One
- Mitochondria, endothelial cell function, and vascular diseases
- (2014) Xiaoqiang Tang et al. Frontiers in Physiology
- The Effect of Coenzyme Q 10 on Morbidity and Mortality in Chronic Heart Failure
- (2014) Svend A. Mortensen et al. JACC-Heart Failure
- Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice
- (2013) Anthony J. Donato et al. AGING CELL
- Transgenic Overexpression of Uncoupling Protein 2 Attenuates Salt-Induced Vascular Dysfunction by Inhibition of Oxidative Stress
- (2013) S. Ma et al. AMERICAN JOURNAL OF HYPERTENSION
- Nitric oxide regulates vascular adaptive mitochondrial dynamics
- (2013) Matthew W. Miller et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Evidence for circulatory benefits of resveratrol in humans
- (2013) Rachel H.X. Wong et al. Annals of the New York Academy of Sciences
- Nox2-Induced Production of Mitochondrial Superoxide in Angiotensin II-Mediated Endothelial Oxidative Stress and Hypertension
- (2013) Sergey I. Dikalov et al. ANTIOXIDANTS & REDOX SIGNALING
- Depolarization of Mitochondria in Endothelial Cells Promotes Cerebral Artery Vasodilation by Activation of Nitric Oxide Synthase
- (2013) Prasad V.G. Katakam et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Mitochondrial Reactive Oxygen Species and Vascular Function
- (2013) Julie K. Freed et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- The role of ATP-sensitive potassium channels in cellular function and protection in the cardiovascular system
- (2013) Andrew Tinker et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mitochondria and Endothelial Function
- (2013) Matthew A. Kluge et al. CIRCULATION RESEARCH
- Uncoupling Protein 2 Impacts Endothelial Phenotype via p53-Mediated Control of Mitochondrial Dynamics
- (2013) Yukio Shimasaki et al. CIRCULATION RESEARCH
- Forecasting the Impact of Heart Failure in the United States
- (2013) Paul A. Heidenreich et al. Circulation-Heart Failure
- Peroxynitrite Disrupts Endothelial Caveolae Leading to eNOS Uncoupling and Diminished Flow-Mediated Dilation in Coronary Arterioles of Diabetic Patients
- (2013) J. Cassuto et al. DIABETES
- Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection
- (2013) Martin F. Kemper et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Antioxidants as therapies: can we improve on nature?
- (2013) Michael P. Murphy FREE RADICAL BIOLOGY AND MEDICINE
- Resveratrol Improves Vascular Function in Patients With Hypertension and Dyslipidemia by Modulating NO Metabolism
- (2013) Albino Carrizzo et al. HYPERTENSION
- Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults
- (2013) Rachel H.X. Wong et al. JOURNAL OF HYPERTENSION
- Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function
- (2013) Jennifer McLachlan et al. JOURNAL OF HYPERTENSION
- The autophagy enhancer spermidine reverses arterial aging
- (2013) Thomas J. LaRocca et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Diversity in Mechanisms of Endothelium-Dependent Vasodilation in Health and Disease
- (2013) Matthew J. Durand et al. MICROCIRCULATION
- mTOR is a key modulator of ageing and age-related disease
- (2013) Simon C. Johnson et al. NATURE
- Oxidative Stress in Cardiovascular Diseases and Obesity: Role of p66Shc and Protein Kinase C
- (2013) Elena De Marchi et al. Oxidative Medicine and Cellular Longevity
- mTOR Inhibition Alleviates Mitochondrial Disease in a Mouse Model of Leigh Syndrome
- (2013) S. C. Johnson et al. SCIENCE
- Angiotensin II-Induced Production of Mitochondrial Reactive Oxygen Species: Potential Mechanisms and Relevance for Cardiovascular Disease
- (2012) Sergey I. Dikalov et al. ANTIOXIDANTS & REDOX SIGNALING
- Adverse Alterations in Mitochondrial Function Contribute to Type 2 Diabetes Mellitus–Related Endothelial Dysfunction in Humans
- (2012) Tinoy J. Kizhakekuttu et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Red wine and equivalent oral pharmacological doses of resveratrol delay vascular aging but do not extend life span in rats
- (2012) Protásio L. da Luz et al. ATHEROSCLEROSIS
- Role of Mitochondrial Ca2+ in the Regulation of Cellular Energetics
- (2012) Brian Glancy et al. BIOCHEMISTRY
- Superoxide generation by complex III: From mechanistic rationales to functional consequences
- (2012) Lea Bleier et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mitochondria and Cardiovascular Aging
- (2012) Dao-Fu Dai et al. CIRCULATION RESEARCH
- Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy Phase 2 (CALERIE Phase 2) screening and recruitment: Methods and results
- (2012) T.M. Stewart et al. Contemporary Clinical Trials
- Sodium nitrite de-stiffening of large elastic arteries with aging: Role of normalization of advanced glycation end-products
- (2012) Bradley S. Fleenor et al. EXPERIMENTAL GERONTOLOGY
- Critical role of hydrogen peroxide signaling in the sequential activation of p38 MAPK and eNOS in laminar shear stress
- (2012) Rosa Bretón-Romero et al. FREE RADICAL BIOLOGY AND MEDICINE
- Metabolic Regulation, Mitochondria and the Life-Prolonging Effect of Rapamycin: A Mini-Review
- (2012) Yong Pan et al. GERONTOLOGY
- Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects
- (2012) Steen Larsen et al. JOURNAL OF PHYSIOLOGY-LONDON
- Translational evidence that impaired autophagy contributes to arterial ageing
- (2012) Thomas J. LaRocca et al. JOURNAL OF PHYSIOLOGY-LONDON
- Sustained activation of AMPK ameliorates age-associated vascular endothelial dysfunction via a nitric oxide-independent mechanism
- (2012) Lisa A. Lesniewski et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Effects of an intensive behavioral weight loss intervention consisting of caloric restriction with or without physical activity on common carotid artery remodeling in severely obese adults
- (2012) Jennifer N. Cooper et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Diet and Healthy Aging
- (2012) Linda Partridge NEW ENGLAND JOURNAL OF MEDICINE
- Beneficial effects of aged garlic extract and coenzyme Q10 on vascular elasticity and endothelial function: The FAITH randomized clinical trial
- (2012) Vahid Nabavi Larijani et al. NUTRITION
- Perinuclear Mitochondrial Clustering Creates an Oxidant-Rich Nuclear Domain Required for Hypoxia-Induced Transcription
- (2012) A.-B. Al-Mehdi et al. Science Signaling
- Role of Inflammation in the Pathogenesis of Arterial Stiffness
- (2012) Sungha Park et al. YONSEI MEDICAL JOURNAL
- Habitually exercising older men do not demonstrate age-associated vascular endothelial oxidative stress
- (2011) Gary L. Pierce et al. AGING CELL
- Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging
- (2011) Amy L. Sindler et al. AGING CELL
- Acute exercise activates AMPK and eNOS in the mouse aorta
- (2011) José M. Cacicedo et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Mitochondria-Targeted Small Molecule Therapeutics and Probes
- (2011) Robin A.J. Smith et al. ANTIOXIDANTS & REDOX SIGNALING
- Regulation of Endothelial Function by Mitochondrial Reactive Oxygen Species
- (2011) Michael E. Widlansky et al. ANTIOXIDANTS & REDOX SIGNALING
- Mitochondrial Oxidative Stress in Aortic Stiffening With Age
- (2011) Rui-Hai Zhou et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice
- (2011) Yun K. Oh et al. ATHEROSCLEROSIS
- Effects of coenzyme Q10 on vascular endothelial function in humans: A meta-analysis of randomized controlled trials
- (2011) Linggen Gao et al. ATHEROSCLEROSIS
- Dietary Inorganic Nitrate Improves Mitochondrial Efficiency in Humans
- (2011) Filip J. Larsen et al. Cell Metabolism
- In Vivo Correction of COX Deficiency by Activation of the AMPK/PGC-1α Axis
- (2011) Carlo Viscomi et al. Cell Metabolism
- Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes Mellitus
- (2011) Sherene M. Shenouda et al. CIRCULATION
- Uncoupling proteins and the control of mitochondrial reactive oxygen species production
- (2011) Ryan J. Mailloux et al. FREE RADICAL BIOLOGY AND MEDICINE
- Oxidative stress and endothelial dysfunction in hypertension
- (2011) Eberhard Schulz et al. HYPERTENSION RESEARCH
- Effects of Coenzyme Q10 on Arterial Stiffness, Metabolic Parameters, and Fatigue in Obese Subjects: A Double-Blind Randomized Controlled Study
- (2011) Yong-Jae Lee et al. JOURNAL OF MEDICINAL FOOD
- Animal and human studies with the mitochondria-targeted antioxidant MitoQ
- (2010) Robin A.J. Smith et al. Annals of the New York Academy of Sciences
- Redox signaling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species
- (2010) Andreas Daiber BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation
- (2010) Xiaolei Qiu et al. Cell Metabolism
- Arterial Stiffness and Cardiovascular Events
- (2010) Gary F. Mitchell et al. CIRCULATION
- Short Communication: Vascular Smooth Muscle Cell Stiffness As a Mechanism for Increased Aortic Stiffness With Aging
- (2010) Hongyu Qiu et al. CIRCULATION RESEARCH
- The sites and topology of mitochondrial superoxide production
- (2010) Martin D. Brand EXPERIMENTAL GERONTOLOGY
- Caloric restriction improves endothelial dysfunction during vascular aging: Effects on nitric oxide synthase isoforms and oxidative stress in rat aorta
- (2010) Michela Zanetti et al. EXPERIMENTAL GERONTOLOGY
- Caloric restriction reverses high-fat diet-induced endothelial dysfunction and vascular superoxide production in C57Bl/6 mice
- (2010) Juha Ketonen et al. HEART AND VESSELS
- Reactive oxygen species and vascular biology: implications in human hypertension
- (2010) Rhian M Touyz et al. HYPERTENSION RESEARCH
- Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure
- (2010) R.H.X. Wong et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Shear stress, SIRT1, and vascular homeostasis
- (2010) Z. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered mitochondrial membrane potential, mass, and morphology in the mononuclear cells of humans with type 2 diabetes
- (2010) Michael E. Widlansky et al. Translational Research
- eNOS uncoupling and endothelial dysfunction in aged vessels
- (2009) Yang-Ming Yang et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Coenzyme Q10 Improves Endothelial Dysfunction in Statin-Treated Type 2 Diabetic Patients
- (2009) S. J. Hamilton et al. DIABETES CARE
- Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy
- (2009) Delyth Graham et al. HYPERTENSION
- Morphological dynamics of mitochondria — A special emphasis on cardiac muscle cells
- (2009) Jennifer Hom et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: Role of circulating factors and SIRT1
- (2009) Anna Csiszar et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
- (2009) David E. Harrison et al. NATURE
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- Induction of autophagy by spermidine promotes longevity
- (2009) Tobias Eisenberg et al. NATURE CELL BIOLOGY
- Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats
- (2008) Zoltan Ungvari et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Nitric Oxide, Tetrahydrobiopterin, Oxidative Stress, and Endothelial Dysfunction in Hypertension
- (2008) Eberhard Schulz et al. ANTIOXIDANTS & REDOX SIGNALING
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span
- (2008) Kevin J. Pearson et al. Cell Metabolism
- Suppression of the JNK Pathway by Induction of a Metabolic Stress Response Prevents Vascular Injury and Dysfunction
- (2008) E. Schulz et al. CIRCULATION
- P53 Impairs Endothelium-Dependent Vasomotor Function Through Transcriptional Upregulation of P66shc
- (2008) Cuk-Seong Kim et al. CIRCULATION RESEARCH
- ASSOCIATION BETWEENPPARGC1AGENE POLYMORPHISMS AND CORONARY ARTERY DISEASE IN A CHINESE POPULATION
- (2008) Yan Zhang et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Upregulation of Mitochondrial Uncoupling Protein-2 by the AMP-Activated Protein Kinase in Endothelial Cells Attenuates Oxidative Stress in Diabetes
- (2008) Z. Xie et al. DIABETES
- Mitochondrial Effects of Estrogen Are Mediated by Estrogen Receptor in Brain Endothelial Cells
- (2008) A. Razmara et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Endothelial cytoskeletal elements are critical for flow-mediated dilation in human coronary arterioles
- (2008) Yanping Liu et al. MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
- The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics
- (2008) Jon O. Lundberg et al. NATURE REVIEWS DRUG DISCOVERY
- Mitochondria: The Hub of Cellular Ca2+ Signaling
- (2008) György Szabadkai et al. PHYSIOLOGY
- Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction
- (2007) Abdulrahman K. Doughan et al. CIRCULATION RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started