A PKD-MFF signaling axis couples mitochondrial fission to mitotic progression

Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition

(2021) Yael Cohen-Sharir et al.   NATURE

Whole-genome doubling confers unique genetic vulnerabilities on tumour cells

(2021) Ryan J. Quinton et al.   NATURE

Drp1 modulates mitochondrial stress responses to mitotic arrest

(2020) Aida Peña-Blanco et al.   CELL DEATH AND DIFFERENTIATION

AMPK-mediated activation of MCU stimulates mitochondrial Ca2+ entry to promote mitotic progression

(2019) Haixin Zhao et al.   NATURE CELL BIOLOGY

Protein kinase D1 inhibition interferes with mitosis progression

(2019) Eduardo Martínez-León et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff)

(2019) Laura Lee et al.   PLoS One

Mitochondrial fusion is required for regulation of mitochondrial DNA replication

(2019) Eduardo Silva Ramos et al.   PLoS Genetics

Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer

(2019) Jae Ho Seo et al.   EBioMedicine

AMPK: Sensing Glucose as well as Cellular Energy Status

(2018) Sheng-Cai Lin et al.   Cell Metabolism

Protein kinase D activation induces mitochondrial fragmentation and dysfunction in cardiomyocytes

(2018) Bong Sook Jhun et al.   JOURNAL OF PHYSIOLOGY-LONDON

Protein Kinase D2 Modulates Cell Cycle by Stabilizing Aurora A Kinase at Centrosomes

(2018) Adhiraj Roy et al.   MOLECULAR CANCER RESEARCH

Protein kinase D1 deletion in adipocytes enhances energy dissipation and protects against adiposity

(2018) Mona C Löffler et al.   EMBO JOURNAL

MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size

(2018) Tommy L. Lewis et al.   Nature Communications

Consequences of mitotic slippage for antimicrotubule drug therapy

(2017) Bing Cheng et al.   ENDOCRINE-RELATED CANCER

Protein kinase D at the Golgi controls NLRP3 inflammasome activation

(2017) Zhirong Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fueling the Cell Division Cycle

(2017) María Salazar-Roa et al.   TRENDS IN CELL BIOLOGY

Functional Mitochondria in Health and Disease

(2017) Patries M. Herst et al.   Frontiers in Endocrinology

MIEF1/2 function as adaptors to recruit Drp1 to mitochondria and regulate the association of Drp1 with Mff

(2017) Rong Yu et al.   Scientific Reports

Dynamics of the mitochondrial network during mitosis

(2016) Gil Kanfer et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

PKD1 Inhibits AMPKα2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells

(2016) Kimberly A. Coughlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ubiquitin ligase CRL2 ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage

(2016) Riju S. Balachandran et al.   JOURNAL OF CELL BIOLOGY

Proteogenomics connects somatic mutations to signalling in breast cancer

(2016) Philipp Mertins et al.   NATURE

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

(2016) E. Q. Toyama et al.   SCIENCE

The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics

(2015) Andrea Musacchio   CURRENT BIOLOGY

Titration of mitochondrial fusion rescuesMff-deficient cardiomyopathy

(2015) Hsiuchen Chen et al.   JOURNAL OF CELL BIOLOGY

Insulin secretory granules control autophagy in pancreatic   cells

(2015) A. Goginashvili et al.   SCIENCE

Genome‐wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

(2014) Laura A Díaz‐Martínez et al.   EMBO JOURNAL

Quantification of Pancreatic Cancer Proteome and Phosphorylome: Indicates Molecular Events Likely Contributing to Cancer and Activity of Drug Targets

(2014) David Britton et al.   PLoS One

Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells

(2014) T. Yi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New insights into the function and regulation of mitochondrial fission

(2013) Hidenori Otera et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

(2013) Oliver C. Losón et al.   MOLECULAR BIOLOGY OF THE CELL

The BAR Domain Protein Arfaptin-1 Controls Secretory Granule Biogenesis at the trans-Golgi Network

(2012) Helmuth Gehart et al.   DEVELOPMENTAL CELL

Global Detection of Protein Kinase D-dependent Phosphorylation Events in Nocodazole-treated Human Cells

(2012) Mirita Franz-Wachtel et al.   MOLECULAR & CELLULAR PROTEOMICS

Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore

(2012) Emily A. Foley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitofusin 1 is degraded at G2/M phase through ubiquitylation by MARCH5

(2012) Yong-Yea Park et al.   Cell Division

The astrin–kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment

(2011) Anja K. Dunsch et al.   JOURNAL OF CELL BIOLOGY

Coupling mitochondrial and cell division

(2011) Koji Yamano et al.   NATURE CELL BIOLOGY

RALA and RALBP1 regulate mitochondrial fission at mitosis

(2011) David F. Kashatus et al.   NATURE CELL BIOLOGY

Quantitative Phosphoproteomics Identifies Substrates and Functional Modules of Aurora and Polo-Like Kinase Activities in Mitotic Cells

(2011) A. N. Kettenbach et al.   Science Signaling

PKD Regulates Membrane Fission to Generate TGN to Cell Surface Transport Carriers

(2011) V. Malhotra et al.   Cold Spring Harbor Perspectives in Biology

Role of protein kinase D signaling in pancreatic cancer

(2010) Sushovan Guha et al.   BIOCHEMICAL PHARMACOLOGY

Protein Kinase D Controls Actin Polymerization and Cell Motility through Phosphorylation of Cortactin

(2010) Tim Eiseler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

(2010) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

(2010) J. V. Olsen et al.   Science Signaling

Regulation of PKD by the MAPK p38δ in Insulin Secretion and Glucose Homeostasis

(2009) Grzegorz Sumara et al.   CELL

Mitochondrial diacylglycerol initiates protein-kinase-D1-mediated ROS signaling

(2009) C. F. Cowell et al.   JOURNAL OF CELL SCIENCE

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

(2009) Mariusz R Wieckowski et al.   Nature Protocols

A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells

(2009) Eric Campeau et al.   PLoS One

Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs

(2008) Karen E. Gascoigne et al.   CANCER CELL

Protein kinase D isozymes activation and localization during mitosis

(2008) Romeo Papazyan et al.   EXPERIMENTAL CELL RESEARCH

The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells

(2008) Shilpa Gandre-Babbe et al.   MOLECULAR BIOLOGY OF THE CELL

Requirement of protein kinase D1 for pathological cardiac remodeling

(2008) J. Fielitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The chromosomal passenger complex and the spindle assembly checkpoint: kinetochore-microtubule error correction and beyond

(2008) Gerben Vader et al.   Cell Division