Protective effect of HINT2 on mitochondrial function via repressing MCU complex activation attenuates cardiac microvascular ischemia–reperfusion injury

Pretreatment of Huoxue Jiedu Formula Ameliorates Myocardial Ischaemia/Reperfusion Injury by Decreasing Autophagy via Activation of the PI3K/AKT/mTOR Pathway

(2021) Linzi Long et al.   Frontiers in Pharmacology

Overexpression of Activating Transcription Factor 3 Alleviates Cardiac Microvascular Ischemia/Reperfusion Injury in Rats

(2021) Yi Liu et al.   Frontiers in Pharmacology

The lncRNA Malat1 regulates microvascular function after myocardial infarction in mice via miR-26b-5p/Mfn1 axis-mediated mitochondrial dynamics

(2021) Yuqiong Chen et al.   Redox Biology

Overexpression of SERCA2a Alleviates Cardiac Microvascular Ischemic Injury by Suppressing Mfn2-Mediated ER/Mitochondrial Calcium Tethering

(2021) Feng Tian et al.   Frontiers in Cell and Developmental Biology

Nitrite and myocardial ischaemia reperfusion injury. Where are we now?

(2021) Kayleigh Griffiths et al.   PHARMACOLOGY & THERAPEUTICS

Overexpression of the histidine triad nucleotide‐binding protein 2 protects cardiac function in the adult mice after acute myocardial infarction

(2020) Mengkang Fan et al.   Acta Physiologica

New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury

(2020) Jin Wang et al.   ANGIOGENESIS

MCUb Induction Protects the Heart from Post-Ischemic Remodeling

(2020) Jiuzhou Huo et al.   CIRCULATION RESEARCH

Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart

(2020) Alyssa Klein et al.   Jove-Journal of Visualized Experiments

Myocardial ischaemia–reperfusion injury and cardioprotection in perspective

(2020) Gerd Heusch   Nature Reviews Cardiology

SERCA overexpression reduces reperfusion-mediated cardiac microvascular damage through inhibition of the calcium/MCU/mPTP/necroptosis signaling pathways

(2020) Chen Li et al.   Redox Biology

Molecular Nature and Physiological Role of the Mitochondrial Calcium Uniporter Channel

(2020) B. Rita Alevriadou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

SERCA Overexpression Improves Mitochondrial Quality Control and Attenuates Cardiac Microvascular Ischemia-Reperfusion Injury

(2020) Ying Tan et al.   Molecular Therapy-Nucleic Acids

Molecular machinery regulating mitochondrial calcium levels: The nuts and bolts of mitochondrial calcium dynamics

(2020) Jyoti Tanwar et al.   MITOCHONDRION

Imaging the injured beating heart intravitally and the vasculoprotection afforded by haematopoietic stem cells

(2019) Dean P J Kavanagh et al.   CARDIOVASCULAR RESEARCH

Cardioprotection of post-ischemic moderate ROS against ischemia/reperfusion via STAT3-induced the inhibition of MCU opening

(2019) Lan Wu et al.   BASIC RESEARCH IN CARDIOLOGY

MCUB Regulates the Molecular Composition of the Mitochondrial Calcium Uniporter Channel to Limit Mitochondrial Calcium Overload During Stress

(2019) Jonathan P. Lambert et al.   CIRCULATION

MCU Up‐regulation contributes to myocardial ischemia‐reperfusion Injury through calpain/OPA‐1–mediated mitochondrial fusion/mitophagy Inhibition

(2019) Lichun Guan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Coronary microvascular obstruction: the new frontier in cardioprotection

(2019) Gerd Heusch   BASIC RESEARCH IN CARDIOLOGY

miR‐181c Activates Mitochondrial Calcium Uptake by Regulating MICU1 in the Heart

(2019) Hemanth N. Banavath et al.   Journal of the American Heart Association

Overexpression of hexokinase 2 reduces mitochondrial calcium overload in coronary endothelial cells of type 2 diabetic mice

(2018) Minglin Pan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

BI1 is associated with microvascular protection in cardiac ischemia reperfusion injury via repressing Syk–Nox2–Drp1-mitochondrial fission pathways

(2018) Hao Zhou et al.   ANGIOGENESIS

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

(2018) Hans Erik Bøtker et al.   BASIC RESEARCH IN CARDIOLOGY

Mitochondrial quality control mechanisms as molecular targets in cardiac ageing

(2018) Anna Picca et al.   Nature Reviews Cardiology

The coronary circulation in acute myocardial ischaemia/reperfusion injury: a target for cardioprotection

(2018) Derek J Hausenloy et al.   CARDIOVASCULAR RESEARCH

The Role of Calcium Handling Mechanisms in Reperfusion Injury

(2018) Konstantinos Pittas et al.   CURRENT PHARMACEUTICAL DESIGN

Relationship between microvascular obstruction and adverse events following primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: an individual patient data pooled analysis from seven randomized trials

(2017) Suzanne de Waha et al.   EUROPEAN HEART JOURNAL

Mitochondrial Ca 2+ transport in the endothelium: regulation by ions, redox signalling and mechanical forces

(2017) B. Rita Alevriadou et al.   Journal of the Royal Society Interface

MICU1 protects against myocardial ischemia/reperfusion injury and its control by the importer receptor Tom70

(2017) Qiang Xue et al.   Cell Death & Disease

Deletion of soluble epoxide hydrolase enhances coronary reactive hyperemia in isolated mouse heart: role of oxylipins and PPARγ

(2016) Ahmad Hanif et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Inhibition of mitochondrial fission as a molecular target for cardioprotection: critical importance of the timing of treatment

(2016) Yi Dong et al.   BASIC RESEARCH IN CARDIOLOGY

Calcium and mitochondria in the regulation of cell death

(2015) Sten Orrenius et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Distinct mPTP activation mechanisms in ischaemia–reperfusion: contributions of Ca2+, ROS, pH, and inorganic polyphosphate

(2015) Lea K. Seidlmayer et al.   CARDIOVASCULAR RESEARCH

Tumor Vessel Normalization by Chloroquine Independent of Autophagy

(2014) Hannelore Maes et al.   CANCER CELL

Genetic deletion of the mitochondrial phosphate carrier desensitizes the mitochondrial permeability transition pore and causes cardiomyopathy

(2014) J Q Kwong et al.   CELL DEATH AND DIFFERENTIATION

Use of labeled tomato lectin for imaging vasculature structures

(2014) Richard T. Robertson et al.   HISTOCHEMISTRY AND CELL BIOLOGY

MICU1 and MICU2 Finely Tune the Mitochondrial Ca2+ Uniporter by Exerting Opposite Effects on MCU Activity

(2014) Maria Patron et al.   MOLECULAR CELL

Characterization of the Effect of the Mitochondrial Protein Hint2 on Intracellular Ca2+ dynamics

(2013) Dieynaba Ndiaye et al.   BIOPHYSICAL JOURNAL

Historical Perspective on the Pathology of Myocardial Ischemia/Reperfusion Injury

(2013) Robert B. Jennings   CIRCULATION RESEARCH

Hyperuricemia induces endothelial dysfunction via mitochondrial Na+/Ca2+ exchanger-mediated mitochondrial calcium overload

(2012) Quan Hong et al.   CELL CALCIUM

Disruption of the histidine triad nucleotide-binding hint2 gene in mice affects glycemic control and mitochondrial function

(2012) Juliette Martin et al.   HEPATOLOGY

Contributions of Nitric Oxide Synthases, Dietary Nitrite/Nitrate, and Other Sources to the Formation of NO Signaling Products

(2011) Alexandra B. Milsom et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis

(2011) Andrea Rasola et al.   CELL CALCIUM

A Novel and Efficient Model of Coronary Artery Ligation and Myocardial Infarction in the Mouse

(2010) Erhe Gao et al.   CIRCULATION RESEARCH

Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

(2010) John W. Elrod et al.   JOURNAL OF CLINICAL INVESTIGATION