Polyphenols and Their Metabolites in Renal Diseases: An Overview

Myricitrin, a Glycosyloxyflavone in Myrica esculenta Bark Ameliorates Diabetic Nephropathy via Improving Glycemic Status, Reducing Oxidative Stress, and Suppressing Inflammation

(2021) Tarun K. Dua et al.   MOLECULES

Updated review on green tea polyphenol epigallocatechin-3-gallate as a cancer epigenetic regulator

(2021) Feng Li et al.   SEMINARS IN CANCER BIOLOGY

Polyphenols and Human Health: The Role of Bioavailability

(2021) Chiara Di Lorenzo et al.   Nutrients

Hyperoside ameliorates diabetic nephropathy induced by STZ via targeting the miR-499–5p/APC axis

(2021) Jingbo Zhou et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Update on diagnosis, pathophysiology, and management of diabetic kidney disease

(2021) Mai Sugahara et al.   NEPHROLOGY

Quercetin Antagonizes Glucose Fluctuation Induced Renal Injury by Inhibiting Aerobic Glycolysis via HIF-1α/miR-210/ISCU/FeS Pathway

(2021) Wei-long Xu et al.   Frontiers in Medicine

An updated pharmacological insight of resveratrol in the treatment of diabetic nephropathy

(2021) Ke-Xue Li et al.   GENE

Mechanisms of Cisplatin-Induced Acute Kidney Injury: Pathological Mechanisms, Pharmacological Interventions, and Genetic Mitigations

(2021) Kristen Renee McSweeney et al.   Cancers

Prevention and management of type II diabetes chronic complications: the role of polyphenols (Mini-Review)

(2021) Arianna Pani et al.   CURRENT MEDICINAL CHEMISTRY

Hydroxytyrosol protects against cisplatin-induced nephrotoxicity via attenuating CKLF1 mediated inflammation, and inhibiting oxidative stress and apoptosis

(2021) Chen Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chronic kidney disease

(2021) Kamyar Kalantar-Zadeh et al.   LANCET

Overview of Beneficial Effects of (Poly)phenol Metabolites in the Context of Neurodegenerative Diseases on Model Organisms

(2021) Diogo Carregosa et al.   Nutrients

Enhancing Bioavailability of Nutraceutically Used Resveratrol and Other Stilbenoids

(2021) Ondrej Vesely et al.   Nutrients

Acute kidney injury

(2021) John A. Kellum et al.   Nature Reviews Disease Primers

Punicalagin prevents cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammatory response, and apoptosis in rats

(2021) Saleem H. Aladaileh et al.   LIFE SCIENCES

Salvianolic Acid C Protects against Cisplatin-Induced Acute Kidney Injury through Attenuation of Inflammation, Oxidative Stress and Apoptotic Effects and Activation of the CaMKK–AMPK–Sirt1-Associated Signaling Pathway in Mouse Models

(2021) Liang-Hsuan Chien et al.   Antioxidants

Suppression of glomerular damage and apoptosis and biomarkers of acute kidney injury induced by acetaminophen toxicity using a combination of resveratrol and quercetin

(2020) Mohammad Dallak et al.   DRUG AND CHEMICAL TOXICOLOGY

Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2020) Boris Bikbov et al.   LANCET

Resveratrol prevents diabetic nephropathy by reducing chronic inflammation and improving the blood glucose memory effect in non-obese diabetic mice

(2020) Yuxin Xian et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Autophagy suppresses resveratrol‑induced apoptosis in renal cell carcinoma 786‑O cells

(2020) Hongwei Yao et al.   Oncology Letters

Quercetin liposomes ameliorate streptozotocin-induced diabetic nephropathy in diabetic rats

(2020) Lixia Tang et al.   Scientific Reports

Anticancer Activity of Rutin and Its Combination with Ionic Liquids on Renal Cells

(2020) Rita Caparica et al.   Biomolecules

Kidney Disease, Race, and GFR Estimation

(2020) Andrew S. Levey et al.   Clinical Journal of the American Society of Nephrology

Cyanidin-3-glucoside from Black Rice Ameliorates Diabetic Nephropathy via Reducing Blood Glucose, Suppressing Oxidative Stress and Inflammation, and Regulating Transforming Growth Factor β1/Smad Expression

(2020) Hong Xing Zheng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway

(2020) Xin An et al.   Nutrients

Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes

(2020) Monica Locatelli et al.   Scientific Reports

Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway

(2020) Zhi-quan Chen et al.   ACTA PHARMACOLOGICA SINICA

Berry fruits modulate kidney dysfunction and urine metabolome in Dahl salt-sensitive rats

(2020) A. Gomes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of Nrf2 dysfunction in the pathogenesis of diabetic nephropathy: Therapeutic prospect of epigallocatechin-3-gallate

(2020) Mohan Thangarajeswari et al.   FREE RADICAL BIOLOGY AND MEDICINE

The mechanisms of ameliorating effect of a green tea polyphenol on diabetic nephropathy based on diacylglycerol kinase α

(2020) Daiki Hayashi et al.   Scientific Reports

Resveratrol: Evidence for Its Nephroprotective Effect in Diabetic Nephropathy

(2020) Vemana Gowd et al.   Advances in Nutrition

Sinapic Acid Ameliorates the Progression of Streptozotocin (STZ)-Induced Diabetic Nephropathy in Rats via NRF2/HO-1 Mediated Pathways

(2020) Ahmed L. Alaofi   Frontiers in Pharmacology

A Pilot Study of a Natural Food Supplement as New Possible Therapeutic Approach in Chronic Kidney Disease Patients

(2020) Annalisa Noce et al.   Pharmaceuticals

Mitochondrial dysfunction and endoplasmic reticulum stress in the promotion of fibrosis in obstructive nephropathy induced by unilateral ureteral obstruction

(2020) Elena Martínez‐Klimova et al.   BIOFACTORS

Cyanidin-3-O-glucoside attenuates high glucose-induced podocytes dysfunction by inhibiting apoptosis and promoting autophagy via activation of SIRT1/AMPK pathway

(2020) Shu Wang et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Resveratrol ameliorates renal damage by inhibiting oxidative stress-mediated apoptosis of podocytes in diabetic nephropathy

(2020) Fang Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Resveratrol reduces gentamicin-induced EMT in the kidney via inhibition of reactive oxygen species and involving TGF-β/Smad pathway

(2020) Olivia N. Beshay et al.   LIFE SCIENCES

Resveratrol decreases high glucose‑induced apoptosis in renal tubular cells via suppressing endoplasmic reticulum stress

(2020) Jing Zhang et al.   Molecular Medicine Reports

Chronic Kidney Disease as Oxidative Stress- and Inflammatory-Mediated Cardiovascular Disease

(2020) Alina Podkowińska et al.   Antioxidants

Bioactivity of dietary polyphenols: The role of metabolites

(2019) Simon Vlad Luca et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

LXRα promotes cell metastasis by regulating the NLRP3 inflammasome in renal cell carcinoma

(2019) KeShan Wang et al.   Cell Death & Disease

Salvianolic Acid A Protects the Kidney against Oxidative Stress by Activating the Akt/GSK-3β/Nrf2 Signaling Pathway and Inhibiting the NF-κB Signaling Pathway in 5/6 Nephrectomized Rats

(2019) Hong-feng Zhang et al.   Oxidative Medicine and Cellular Longevity

Formononetin attenuates kidney damage in type 2 diabetic rats

(2019) Manisha J. Oza et al.   LIFE SCIENCES

Honokiol Attenuates Sepsis-Associated Acute Kidney Injury via the Inhibition of Oxidative Stress and Inflammation

(2019) Shilin Xia et al.   INFLAMMATION

Protective effects of resveratrol on acute kidney injury in rats with sepsis

(2019) Cong-Juan Luo et al.   BIOMEDICAL PAPERS-OLOMOUC

Ramipril and resveratrol co‐treatment attenuates RhoA/ROCK pathway‐regulated early‐stage diabetic nephropathy‐associated glomerulosclerosis in streptozotocin‐induced diabetic rats

(2019) Xiang Peng et al.   ENVIRONMENTAL TOXICOLOGY

Quercetin improves lipid metabolism via SCAP-SREBP2-LDLr signaling pathway in early stage diabetic nephropathy

(2019) Xiyuan Jiang et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Health Benefits of Resveratrol in Kidney Disease: Evidence from In Vitro and In Vivo Studies

(2019) Danja J. Den Hartogh et al.   Nutrients

Resveratrol Protects Against Post-Contrast Acute Kidney Injury in Rabbits With Diabetic Nephropathy

(2019) Yongfang Wang et al.   Frontiers in Pharmacology

Quercetin inhibited mesangial cell proliferation of early diabetic nephropathy through the Hippo pathway

(2019) Du Lei et al.   PHARMACOLOGICAL RESEARCH

Resveratrol improves left ventricular remodeling in chronic kidney disease via Sirt1‐mediated regulation of FoxO1 activity and MnSOD expression

(2019) Peipei Li et al.   BIOFACTORS

Mechanism and therapeutic prospect of resveratrol combined with TRAIL in the treatment of renal cell carcinoma

(2019) Yan Zeng et al.   CANCER GENE THERAPY

Ellagic Acid Ameliorates Renal Ischemic-Reperfusion Injury Through NOX4/JAK/STAT Signaling Pathway

(2019) Qiong Liu et al.   INFLAMMATION

Acute kidney injury

(2019) Claudio Ronco et al.   LANCET

Microbial Phenolic Metabolites: Which Molecules Actually Have an Effect on Human Health?

(2019) María Marhuenda-Muñoz et al.   Nutrients

The olive constituent oleuropein exerts nephritic protective effects on diabetic nephropathy in db/db mice

(2019) Yan Liu et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Nanoparticulated Honokiol Mitigates Cisplatin-Induced Chronic Kidney Injury by Maintaining Mitochondria Antioxidant Capacity and Reducing Caspase 3-Associated Cellular Apoptosis

(2019) Hung-Ting Liu et al.   Antioxidants

US Renal Data System 2019 Annual Data Report: Epidemiology of Kidney Disease in the United States

(2019) Rajiv Saran et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Bergenin impedes the generation of extracellular matrix in glomerular mesangial cells and ameliorates diabetic nephropathy in mice by inhibiting oxidative stress via the mTOR/β-TrcP/Nrf2 pathway

(2019) Simiao Qiao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Myricitrin protects against cisplatin-induced kidney injury by eliminating excessive reactive oxygen species

(2019) Ruiqian Li et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Bioavailability and pharmacokinetic profile of grape pomace phenolic compounds in humans

(2018) Fabio Castello et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Ameliorative potential of sitagliptin and/or resveratrol on experimentally-induced clear cell renal cell carcinoma

(2018) Ahmed M. Kabel et al.   BIOMEDICINE & PHARMACOTHERAPY

Protocatechuic acid ameliorates high glucose-induced extracellular matrix accumulation in diabetic nephropathy

(2018) Yali Ma et al.   BIOMEDICINE & PHARMACOTHERAPY

Resveratrol inhibits proliferation, migration and invasion via Akt and ERK1/2 signaling pathways in renal cell carcinoma cells

(2018) Yuwan Zhao et al.   BIOMEDICINE & PHARMACOTHERAPY

Cyanidin-3- O -glucoside ameliorates diabetic nephropathy through regulation of glutathione pool

(2018) Yan Qin et al.   BIOMEDICINE & PHARMACOTHERAPY

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal

(2018) Thomas J. Mitchell et al.   CELL

Clinical Pharmacokinetics in Kidney Disease

(2018) Tom N. Lea-Henry et al.   Clinical Journal of the American Society of Nephrology

Polyphenols and Bioavailability: an update

(2018) Hui Teng et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Anthocyanins inhibit high glucose-induced renal tubular cell apoptosis caused by oxidative stress in db/db mice

(2018) Jinying Wei et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Curcumin alleviates ischemia reperfusion-induced late kidney fibrosis through the APPL1/Akt signaling pathway

(2018) Chen Hongtao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Update of pathophysiology and management of diabetic kidney disease

(2018) Yi-Chih Lin et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Kidney protection effects of dihydroquercetin on diabetic nephropathy through suppressing ROS and NLRP3 inflammasome

(2018) Tao Ding et al.   PHYTOMEDICINE

Resveratrol influences platinum pharmacokinetics: A novel mechanism in protection against cisplatin-induced nephrotoxicity

(2018) Mostafa A. Darwish et al.   TOXICOLOGY LETTERS

Honokiol, a Polyphenol Natural Compound, Attenuates Cisplatin-Induced Acute Cytotoxicity in Renal Epithelial Cells Through Cellular Oxidative Stress and Cytoskeleton Modulations

(2018) Tse-En J. Wang et al.   Frontiers in Pharmacology

Ellagic acid ameliorates cisplatin toxicity in chemically induced colon carcinogenesis

(2018) Yasmeen Goyal et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Oxidative stress in chronic kidney disease

(2018) Kristien Daenen et al.   PEDIATRIC NEPHROLOGY

Resveratrol ameliorates sepsis‑induced acute kidney injury in a pediatric rat model via Nrf2 signaling pathway

(2018) Yan Wang et al.   Experimental and Therapeutic Medicine

Protective Effects of Epigallocatechin-3-Gallate from Green Tea in Various Kidney Diseases

(2018) Rattiyaporn Kanlaya et al.   Advances in Nutrition

Trends in the levels of urine and serum creatinine: data from NHANES 2001–2014

(2017) Ram B. Jain   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Curcumin prevents cisplatin-induced renal alterations in mitochondrial bioenergetics and dynamic

(2017) Bibiana Ortega-Domínguez et al.   FOOD AND CHEMICAL TOXICOLOGY

Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating CKIP-1 to resist HG-induced up-regulation of FN and ICAM-1 in GMCs and diabetic mice kidneys

(2017) Wenyan Gong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Kaempferol Inhibits the Invasion and Migration of Renal Cancer Cells through the Downregulation of AKT and FAK Pathways

(2017) Tung-Wei Hung et al.   International Journal of Medical Sciences

Quercetin nanoparticle complex attenuated diabetic nephropathy via regulating the expression level of ICAM-1 on endothelium

(2017) Fei Tong et al.   International Journal of Nanomedicine

Impact of EGCG Supplementation on the Progression of Diabetic Nephropathy in Rats: An Insight into Fibrosis and Apoptosis

(2017) Thangarajeswari Mohan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Polydatin impairs mitochondria fitness and ameliorates podocyte injury by suppressing Drp1 expression

(2017) Zheng Ni et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Chronic Kidney Disease

(2017) Angela C Webster et al.   LANCET

TNF-α, IL-6 and IL-10 expressions, responsible for disparity in action of curcumin against cisplatin-induced nephrotoxicity in rats

(2017) Parveen Kumar et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Resveratrol-mediated apoptosis in renal cell carcinoma via the p53/AMP‑activated protein kinase/mammalian target of rapamycin autophagy signaling pathway

(2017) Qingjun Liu et al.   Molecular Medicine Reports

Epigallocatechin-3-gallate protects from high glucose induced podocyte apoptosis via suppressing endoplasmic reticulum stress

(2017) Chunhong Xiang et al.   Molecular Medicine Reports

Resveratrol-loaded nanoparticles conjugated with kidney injury molecule-1 as a drug delivery system for potential use in chronic kidney disease

(2017) Yuh-Feng Lin et al.   Nanomedicine

Oxidative Stress and Acute Kidney Injury in Critical Illness: Pathophysiologic Mechanisms—Biomarkers—Interventions, and Future Perspectives

(2017) Paraskevi Pavlakou et al.   Oxidative Medicine and Cellular Longevity

Targeting miRNAs by polyphenols: Novel therapeutic strategy for cancer

(2017) Kasi Pandima Devi et al.   SEMINARS IN CANCER BIOLOGY

A systematic meta-analysis on the efficacy of pre-clinically tested nephroprotectants at preventing aminoglycoside nephrotoxicity

(2017) Laura Vicente-Vicente et al.   TOXICOLOGY

Anthocyanins and Flavanones Are More Bioavailable than Previously Perceived: A Review of Recent Evidence

(2017) Colin D. Kay et al.   Annual Review of Food Science and Technology

Polyphenolic Nutrients in Cancer Chemoprevention and Metastasis: Role of the Epithelial-to-Mesenchymal (EMT) Pathway

(2017) Haneen Amawi et al.   Nutrients

Consumption of fruits and vegetables and risk of renal cell carcinoma: a meta-analysis of observational studies

(2017) Shaojing Zhang et al.   Oncotarget

Resveratrol protects against early polymicrobial sepsis-induced acute kidney injury through inhibiting endoplasmic reticulum stress-activated NF-κB pathway

(2017) Nian Wang et al.   Oncotarget

Molecular Mechanisms of Curcumin Renoprotection in Experimental Acute Renal Injury

(2017) Youling Fan et al.   Frontiers in Pharmacology

Chronic kidney disease

(2017) Paola Romagnani et al.   Nature Reviews Disease Primers

Renal cell carcinoma

(2017) James J. Hsieh et al.   Nature Reviews Disease Primers

Green Tea Polyphenol Prevents Diabetic Rats From Acute Kidney Injury After Cardiopulmonary Bypass

(2016) Masaki Funamoto et al.   ANNALS OF THORACIC SURGERY

Identification and quantification of novel cranberry-derived plasma and urinary (poly)phenols

(2016) Rodrigo P. Feliciano et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part A: Renal, Penile, and Testicular Tumours

(2016) Holger Moch et al.   EUROPEAN UROLOGY

The role of natural polyphenols in cell signaling and cytoprotection against cancer development

(2016) Hanna Lewandowska et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Molecular mechanisms underlying attenuation of cisplatin-induced acute kidney injury by epicatechin gallate

(2016) Salma Malik et al.   LABORATORY INVESTIGATION

Sinapic acid mitigates gentamicin-induced nephrotoxicity and associated oxidative/nitrosative stress, apoptosis, and inflammation in rats

(2016) Mushtaq Ahmad Ansari et al.   LIFE SCIENCES

Resveratrol attenuates acute kidney injury by inhibiting death receptor-mediated apoptotic pathways in a cisplatin-induced rat model

(2016) Qiufa Hao et al.   Molecular Medicine Reports

Curcumin attenuates cyclosporine A-induced renal fibrosis by inhibiting hypermethylation of the klotho promoter

(2016) Ying Hu et al.   Molecular Medicine Reports

Plasma and Urinary Phenolic Profiles after Acute and Repetitive Intake of Wild Blueberry

(2016) Rodrigo Feliciano et al.   MOLECULES

Salvianolic Acid B Prevents Iodinated Contrast Media-Induced Acute Renal Injury in Rats via the PI3K/Akt/Nrf2 Pathway

(2016) Liu Tongqiang et al.   Oxidative Medicine and Cellular Longevity

SIRT1/3 Activation by Resveratrol Attenuates Acute Kidney Injury in a Septic Rat Model

(2016) Siqi Xu et al.   Oxidative Medicine and Cellular Longevity

Resveratrol attenuates constitutive STAT3 and STAT5 activation through induction of PTPε and SHP-2 tyrosine phosphatases and potentiates sorafenib-induced apoptosis in renal cell carcinoma

(2016) Chulwon Kim et al.   BMC Nephrology

Epigallocatechin-3-gallate inhibits migration and invasion of human renal carcinoma cells by downregulating matrix metalloproteinase-2 and matrix metalloproteinase-9

(2016) SHAO-JUN CHEN et al.   Experimental and Therapeutic Medicine

Resveratrol promotes regression of renal carcinoma cells via a renin-angiotensin system suppression-dependent mechanism

(2016) Jianchang Li et al.   Oncology Letters

Polydatin Inhibits Mitochondrial Dysfunction in the Renal Tubular Epithelial Cells of a Rat Model of Sepsis-Induced Acute Kidney Injury

(2015) Youguang Gao et al.   ANESTHESIA AND ANALGESIA

Epigallocatechin-3-Gallate Attenuates Oxidative Stress and Inflammation in Obstructive Nephropathy via NF-κB and Nrf2/HO-1 Signalling Pathway Regulation

(2015) Yanqiu Wang et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Resveratrol ameliorates cisplatin-induced oxidative injury in New Zealand rabbits

(2015) Yilmaz Cigremis et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Curcumin Promotes Cell Cycle Arrest and Inhibits Survival of Human Renal Cancer Cells by Negative Modulation of the PI3K/AKT Signaling Pathway

(2015) Hao Zhang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Modification of Antitumor Immunity and Tumor Microenvironment by Resveratrol in Mouse Renal Tumor Model

(2015) Liang Chen et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Curcumin Attenuates Gentamicin-Induced Kidney Mitochondrial Alterations: Possible Role of a Mitochondrial Biogenesis Mechanism

(2015) Mario Negrette-Guzmán et al.   Evidence-based Complementary and Alternative Medicine

Epigallocatechin-3-gallate protects against cisplatin-induced nephrotoxicity by inhibiting endoplasmic reticulum stress-induced apoptosis

(2015) Binbin Chen et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro

(2015) YEN TA HUANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells

(2015) Kaipeng Huang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Resveratrol attenuates lipopolysaccharide-induced acute kidney injury by suppressing inflammation driven by macrophages

(2015) Liang Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The renoprotective effect of curcumin in cisplatin-induced nephrotoxicity

(2015) Sıddık Ugur et al.   RENAL FAILURE

Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties

(2015) Laura Marín et al.   Biomed Research International

Protective effects of epigallocatechin gallate (EGCG) on streptozotocin-induced diabetic nephropathy in mice

(2014) Sang Pil Yoon et al.   ACTA HISTOCHEMICA

Comparative In Vivo Evaluations of Curcumin and Its Analog Difluorinated Curcumin Against Cisplatin-Induced Nephrotoxicity

(2014) Kazim Sahin et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

The pharmacokinetics of anthocyanins and their metabolites in humans

(2014) R M de Ferrars et al.   BRITISH JOURNAL OF PHARMACOLOGY

Epigallocatechin-3-gallate Sensitizes Human 786-O Renal Cell Carcinoma Cells to TRAIL-Induced Apoptosis

(2014) Ruojing Wei et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Oligonol, a Low-Molecular-Weight Polyphenol Derived from Lychee Fruit, Attenuates Diabetes-Induced Renal Damage through the Advanced Glycation End Product–Related Pathway in db/db Mice

(2014) Chan Hum Park et al.   JOURNAL OF NUTRITION

(+)-Catechin ameliorates diabetic nephropathy by trapping methylglyoxal in type 2 diabetic mice

(2014) Dina Zhu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Curcumin Significantly Enhances Dual PI3K/Akt and mTOR Inhibitor NVP-BEZ235-Induced Apoptosis in Human Renal Carcinoma Caki Cells through Down-Regulation of p53-Dependent Bcl-2 Expression and Inhibition of Mcl-1 Protein Stability

(2014) Bo Ram Seo et al.   PLoS One

Grape seed proanthocyanidin extracts ameliorate podocyte injury by activating peroxisome proliferator-activated receptor-γ coactivator 1α in low-dose streptozotocin-and high-carbohydrate/high-fat diet-induced diabetic rats

(2014) Lei Bao et al.   Food & Function

EGCG inhibit chemical reactivity of iron through forming an Ngal–EGCG–iron complex

(2013) Guan-Hu Bao et al.   BIOMETALS

Mitochondria-mediated mitigatory role of curcumin in cisplatin-induced nephrotoxicity

(2013) Mohammad Waseem et al.   CELL BIOCHEMISTRY AND FUNCTION

Explicit role of peroxisome proliferator–activated receptor gamma in gallic acid–mediated protection against ischemia-reperfusion–induced acute kidney injury in rats

(2013) Jaswinder Pal Singh et al.   JOURNAL OF SURGICAL RESEARCH

Resveratrol as a therapeutic agent for renal fibrosis induced by unilateral ureteral obstruction

(2013) Jin Liang et al.   RENAL FAILURE

Resveratrol attenuates cisplatin renal cortical cytotoxicity by modifying oxidative stress

(2013) Monica A. Valentovic et al.   TOXICOLOGY IN VITRO

Factors associated with 24-hour urinary volume: the Swiss salt survey

(2013) Tobias Schoen et al.   BMC Nephrology

Phenol-Explorer 3.0: a major update of the Phenol-Explorer database to incorporate data on the effects of food processing on polyphenol content

(2013) J. A. Rothwell et al.   Database-The Journal of Biological Databases and Curation

Drug-Induced Nephrotoxicity and Its Biomarkers

(2012) Sun-Young Kim et al.   Biomolecules & Therapeutics

Curcumin ameliorates cisplatin-induced nephrotoxicity by inhibiting renal inflammation in mice

(2012) Masaaki Ueki et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-κB signaling pathway in rat glomerular mesangial cells

(2012) Xi Xie et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Reno-protective effects of epigallocatechingallate in a small piglet model of extracorporeal circulation

(2012) Miriam Twal et al.   PHARMACOLOGICAL RESEARCH

Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: Plausible role of NF-κB

(2012) Muneeb U. Rehman et al.   TOXICOLOGY LETTERS

Alleviation of cisplatin-induced acute kidney injury using phytochemical polyphenols is accompanied by reduced accumulation of indoxyl sulfate in rats

(2011) Masahiro Kusumoto et al.   Clinical and Experimental Nephrology

Tannic acid mitigates cisplatin-induced nephrotoxicity in mice

(2011) S T Ahmad et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury

(2011) Joseph H. Holthoff et al.   KIDNEY INTERNATIONAL

Inhibitory effect of resveratrol on the expression of the VEGF gene and proliferation in renal cancer cells

(2011) Huizhen Zhang   Molecular Medicine Reports

Evaluation of renal protective effects of the green-tea (EGCG) and red grape resveratrol: role of oxidative stress and inflammatory cytokines

(2011) A.M. El-Mowafy et al.   NATURAL PRODUCT RESEARCH

Epigallocatechin-3-gallate protects kidneys from ischemia reperfusion injury by HO-1 upregulation and inhibition of macrophage infiltration

(2011) Yoichi Kakuta et al.   TRANSPLANT INTERNATIONAL

Bioavailability of the Polyphenols: Status and Controversies

(2010) Massimo D’Archivio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of Milk on the Urinary Excretion of Microbial Phenolic Acids after Cocoa Powder Consumption in Humans

(2010) Mireia Urpi-Sarda et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Novel chemotherapeutic and renal protective effects for the green tea (EGCG): Role of oxidative stress and inflammatory-cytokine signaling

(2010) A.M. El-Mowafy et al.   PHYTOMEDICINE

Interaction between Phenolics and Gut Microbiota: Role in Human Health

(2009) María V. Selma et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Green Tea Flavan-3-ols: Colonic Degradation and Urinary Excretion of Catabolites by Humans

(2009) Suri Roowi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Targeted metabolic profiling of phenolics in urine and plasma after regular consumption of cocoa by liquid chromatography–tandem mass spectrometry

(2009) Mireia Urpi-Sarda et al.   JOURNAL OF CHROMATOGRAPHY A

A Metabolite Profiling Approach to Identify Biomarkers of Flavonoid Intake in Humans

(2009) Wai Mun Loke et al.   JOURNAL OF NUTRITION

EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression

(2009) Ding   ONCOLOGY REPORTS